Compounds > simendan
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simendan and Endotoxemia

simendan has been researched along with Endotoxemia in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, HC; Ka, SM; Liaw, WJ; Tsai, HJ; Tsao, CM; Wang, CC; Wu, CC1
Bent, F; Kopitz, J; Plaschke, K; Wagner, S; Zorn, M1
Dekhuijzen, PN; Heunks, LM; Linkels, M; Scheffer, GJ; Schellekens, WJ; van der Hoeven, JG; van Hees, HW1
Friedrich, O; Hein, S; Schürmann, S; Schüttler, J; Wagner, S1
Bendall, J; Chew, MS; Hawthorne, WJ; Huang, S; McLean, A; Simond, D; Ting, I; Whereat, S1
Abrass, CK; Hanson, SY; Johnson, AC; Lund, S; Zager, RA1
Barán, M; Canales, HS; Dubin, A; Edul, VS; Estenssoro, E; Maskin, B; Murias, G; Pozo, MO; Sottile, JP1
Barán, M; Canales, HS; Dubin, A; Edul, VS; Estenssoro, E; Etcheverry, G; Maskin, B; Murias, G; Pozo, MO; Sottile, JP1
Blomquist, S; Cunha-Goncalves, D; Dahm, P; Grins, E; Perez-de-Sa, V; Thörne, J1
Ertmer, C; Pinto, BB; Rehberg, S; Westphal, M1

Reviews

1 review(s) available for simendan and Endotoxemia

ArticleYear
Role of levosimendan in sepsis and septic shock.
    Current opinion in anaesthesiology, 2008, Volume: 21, Issue:2

    Topics: Animals; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Endotoxemia; Heart Failure; Humans; Hydrazones; Potassium Channels; Pyridazines; Sepsis; Shock, Septic; Simendan

2008

Other Studies

9 other study(ies) available for simendan and Endotoxemia

ArticleYear
Levosimendan mitigates coagulopathy and organ dysfunction in rats with endotoxemia.
    Journal of the Chinese Medical Association : JCMA, 2017, Volume: 80, Issue:7

    Topics: Animals; Blood Coagulation Disorders; Endotoxemia; Hydrazones; Interleukin-6; Lipopolysaccharides; Male; Multiple Organ Failure; Pyridazines; Rats; Rats, Wistar; Simendan; Thrombelastography

2017
In contrast to its anti-inflammatory and anti-apoptotic peripheral effect, levosimendan failed to induce a long-term neuroprotective effect in a rat model of mild septic encephalopathy: a pilot study.
    Neuroscience letters, 2014, Feb-07, Volume: 560

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Brain; Cognition Disorders; Corticosterone; Cytokines; Endotoxemia; Hydrazones; Lipopolysaccharides; Male; Maze Learning; Neuroprotective Agents; Pilot Projects; Pyridazines; Rats, Wistar; Simendan; Spleen; Time Factors

2014
Levosimendan affects oxidative and inflammatory pathways in the diaphragm of ventilated endotoxemic mice.
    Critical care (London, England), 2015, Mar-02, Volume: 19

    Topics: Aldehydes; Animals; Cardiotonic Agents; Chemokines; Diaphragm; Endotoxemia; Hydrazones; Inflammation; Interleukins; Mice, Inbred C57BL; Models, Animal; Nitric Oxide Synthase; Pyridazines; Respiration, Artificial; RNA, Messenger; Simendan

2015
Septic cardiomyopathy in rat LPS-induced endotoxemia: relative contribution of cellular diastolic Ca(2+) removal pathways, myofibrillar biomechanics properties and action of the cardiotonic drug levosimendan.
    Basic research in cardiology, 2015, Volume: 110, Issue:5

    Topics: Animals; Calcium; Cardiomyopathies; Cardiotonic Agents; Endotoxemia; Hemodynamics; Homeostasis; Hydrazones; Lipopolysaccharides; Male; Microscopy, Confocal; Myofibrils; Pyridazines; Rats; Rats, Wistar; Sarcolemma; Simendan

2015
No beneficial effects of levosimendan in acute porcine endotoxaemia.
    Acta anaesthesiologica Scandinavica, 2011, Volume: 55, Issue:7

    Topics: Animals; Blood Pressure; Cardiotonic Agents; Cytokines; Echocardiography; Endotoxemia; Heart Function Tests; Hemodynamics; Hydrazones; Hypertension, Pulmonary; Kidney Function Tests; Lactic Acid; Lipopolysaccharides; Liver Function Tests; Pulmonary Circulation; Pyridazines; Regional Blood Flow; Sample Size; Simendan; Swine; Water-Electrolyte Balance

2011
Levosimendan protects against experimental endotoxemic acute renal failure.
    American journal of physiology. Renal physiology, 2006, Volume: 290, Issue:6

    Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Cardiotonic Agents; Chemokine CCL2; Endotoxemia; Glyburide; Hydrazones; Inflammation; Ischemia; Kidney; Lipopolysaccharides; Male; Mesangial Cells; Mice; Nitric Oxide; Potassium Channel Blockers; Potassium Channels; Pyridazines; Simendan; Tumor Necrosis Factor-alpha

2006
Effects of levosimendan in normodynamic endotoxaemia: a controlled experimental study.
    Resuscitation, 2006, Volume: 69, Issue:2

    Topics: Acidosis; Animals; Disease Models, Animal; Endotoxemia; Escherichia coli Infections; Hemodynamics; Hydrazones; Intestinal Mucosa; Lactic Acid; Oxygen; Pyridazines; Sheep; Simendan; Vasodilator Agents

2006
Effects of levosimendan and dobutamine in experimental acute endotoxemia: a preliminary controlled study.
    Intensive care medicine, 2007, Volume: 33, Issue:3

    Topics: Acidosis; Analysis of Variance; Animals; Cardiotonic Agents; Dobutamine; Endotoxemia; Hydrazones; Lactic Acid; Oxygen; Prospective Studies; Pyridazines; Random Allocation; Sheep; Shock, Septic; Simendan; Splanchnic Circulation

2007
Cardiovascular effects of levosimendan in the early stages of endotoxemia.
    Shock (Augusta, Ga.), 2007, Volume: 28, Issue:1

    Topics: Animals; Calcium; Cardiotonic Agents; Coronary Circulation; Endotoxemia; Female; Hydrazones; Lipopolysaccharides; Myocardium; Oxygen Consumption; Pulmonary Circulation; Pyridazines; Simendan; Sus scrofa; Time Factors

2007