Page last updated: 2024-08-24

simendan and Cardiac Output, Low

simendan has been researched along with Cardiac Output, Low in 98 studies

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's35 (35.71)29.6817
2010's46 (46.94)24.3611
2020's17 (17.35)2.80

Authors

AuthorsStudies
Belletti, A; Bianzina, S; Momeni, M; Silvetti, S1
Eagle, SS; Londergan, BP; Staudt, GE1
Dosta-Herrera, JJ; Gutiérrez-Riveroll, KI; Mejía Picazo, HJ1
Lapere, M; Rega, F; Rex, S1
Alexander, JH; Argenziano, M; de Varennes, B; Duncan, AI; Fremes, S; Goodman, SG; Kochar, A; Lopes, RD; Mazer, DC; Mehta, RH; van Diepen, S; Westerhout, CM; Whitlock, R; Zheng, Y1
Mielke, JAR; Ramakrishna, H; Welker, CC1
Dresbach, T; Geipel, A; Holcher, S; Kipfmueller, F; Leyens, J; Mueller, A; Schroeder, L; Strizek, B1
Barrera Serrano, R; Bellido Estevez, I; Cruz Mañas, J; Escalona Belmonte, JJ; Gomez Luque, A; Guerrero Orriach, JL; Hernandez Rodriguez, P; Malo Manso, A; Navarro Arce, I; Raigón Ponferrada, A; Ramirez Aliaga, M; Ramirez Fernandez, A; Rubio Navarro, M; Toledo Medina, CS1
Choi, YH; Deppe, AC; Djordjevic, I; Eghbalzadeh, K; Esser, M; Liakopoulos, O; Madershahian, N; Maier, J; Merkle, J; Sabashnikov, A; Wahlers, TCW; Weber, C1
Cui, C; Fan, Y; Tan, Q; Wang, A; Wang, F; Wang, G; Wang, J; Zhang, J; Zi, J1
Di Chiara, L; Di Molfetta, A; Haiberger, R; Iacobelli, R; Marinari, E; Ricci, Z; Toscano, A1
Beretta-Piccoli, X; Biarent, D; De Bels, D; Honore, PM; Redant, S1
Abubakirov, MN; Belletti, A; Bianchi, A; Brazzi, L; Calabrò, MG; Crivellari, M; Di Tomasso, N; Fominskiy, EV; Garofalo, E; Grigoryev, EV; Guarracino, F; Landoni, G; Lembo, R; Likhvantsev, VV; Lomivorotov, VV; Monaco, F; Oriani, A; Pasyuga, VV; Paternoster, G; Pisano, A; Scandroglio, AM; Yavorovskiy, A; Zangrillo, A1
Álvarez-Castillo, A; Ferrer-Rodríguez, J; García-González, MJ; Iribarren-Sarrías, JL; Jiménez-Rivera, JJ; Jorge-Pérez, P; Lacalzada-Almeida, J; Martínez-Sanz, R; Montoto-López, J; Pérez-Hernández, R1
Dashkevich, A; Juchem, G; Kilger, E; Mehringer, L; Schünemann, M; Weis, M; Woehrle, T1
Efremov, L; Frantz, S; Mikolajczyk, R; Schumann, J; Sedding, D; Tongers, J; Uhlig, K1
Axelsson, B; Grafver, I; Jansson, K; Kiszakiewicz, L; Nilsson, KF; Oikonomakis, I; Seilitz, J1
Filipiak, KJ; Gasecka, A; Jaguszewski, MJ; Szarpak, L1
Belletti, A; Cassina, T; Clivio, S; Putzu, A1
Alexander, JH; Anstrom, KJ; Argenziano, M; Bozinovski, J; Duncan, A; Fremes, S; Goodman, SG; Harrington, RA; Harrison, RW; Hay, D; Heringlake, M; Jankowich, R; Kalavrouziotis, D; Leimberger, JD; Levy, JH; Luber, J; Marcel, R; Mehta, RH; Meza, J; Murphy, E; Nagpal, D; Park, S; Soltesz, EG; Toller, W; van Diepen, S; Wang, A1
Abubakirov, MN; Alvaro, G; Amantea, B; Baiocchi, M; Belletti, A; Bellomo, R; Bertini, P; Bianchi, A; Boboshko, VA; Bove, T; Brazzi, L; Calabrò, MG; Grigoryev, EV; Guarracino, F; Landoni, G; Lembo, R; Likhvantsev, VV; Lobreglio, R; Lomivorotov, VV; Michienzi, MG; Monaco, F; Pappalardo, F; Pasyuga, VV; Pisano, A; Salgado-Filho, MF; Scandroglio, AM; Shukevich, DL; Verniero, L; Zabelina, TS; Zangrillo, A1
Desai, AS; Jarcho, JA1
Hummel, J; Rücker, G; Stiller, B2
Aït Hamou, N; Amour, J; Boughenou, MF; Boyer, J; Carillion, A; Caruba, T; Charles-Nelson, A; Chatellier, G; Cholley, B; Desebbe, O; Durand, M; Fellahi, JL; Girard, C; Grosjean, S; Guidon, C; Guinet, P; Lévy, F; Menasché, P; Miguet, B; Ouattara, A; Pirracchio, R; Radutoiu, M; Robin, E; Rosier, S; Rozec, B; Squara, P; Villacorta, J1
Arcadipane, A; Knight, JB; Lorini, FL; Morelli, A; Pastore, F; Sanfilippo, F; Santonocito, C; Scolletta, S; Tritapepe, L1
Frantz, S; Henrich, EC; Prondzinsky, R; Schumann, J; Strobl, H; Thiele, H; Unverzagt, S; Weiche, S; Werdan, K1
Incalzi, RA; Massini, C; Migale, M; Santillo, E1
Abowali, H; Abuzaid, AS; Elbadawi, A; Elgendy, IY; Goswamy, V; London, B; Megaly, M; Mentias, A; Saad, M; Shahin, HI1
González, JM; González, L; Juarez, P; Portela, F; Sadaba, R; Santana, L; Tena, MÁ; Urso, S1
Chen, P; Li, Z; Tian, X; Wang, J; Wang, Z; Wu, X; Yan, T1
Cheng, B; Gong, Y; He, X; Wang, B1
Di Molfetta, P; Fiore, C; Gregorini, R; Santarpino, G1
Grebenshchikov, OA; Lar'kov, RN; Likhvantsev, VV; Marchenko, DN; Ovezov, AM; Philippovskaya, ZS; Skripkin, YV; Sungurov, VA; Timoshin, SS; Ubasev, YV; Zabelina, TS1
Chen, L; He, Y; Qing, X; Zhang, Y; Zhu, J1
Pirracchio, R1
Fletcher, N1
Caruba, T; Cholley, B1
Banasiak, W; Biegus, J; Jankowska, EA; Kulej, K; Ponikowski, P; Szachniewicz, J; Zymliński, R1
Alvarez, J; Baluja, A; Caruezo, V; Castroagudin, J; Otero, P; Rial, M; Rodriguez, A; Rodriguez, I; Rodriguez, J; Selas, S; Taboada, M; Tome, S; Veiras, S1
Buerke, M; Haerting, J; Hirsch, K; Prondzinsky, R; Thiele, H; Unverzagt, S; Wachsmuth, L; Werdan, K1
Firlinger, F; Gegenhuber, A; Lenz, K; Lohr, G; Piringer, P1
Gluud, C; Keus, F; Koster, G; Scheeren, TW; van der Horst, IC; Wetterslev, J; Zijlstra, JG1
Burkhardt, BE; Rücker, G; Stiller, B1
Balzer, F; Braun, JP; Erb, JM; Geyer, T; Grubitzsch, H; Kastrup, M; Sander, M; Spies, CD; Treskatsch, S; Wernecke, KD1
Altarabsheh, SE; Avery, EG; Cho, YH; Deo, SV; Hang, D; Lim, JY; Markowitz, AH; McGraw, M; Park, SJ; Rababa'h, A1
Bautista-Hernandez, V; Ferrer-Barba, A; Gonzalez-Rivera, I1
Ertl, G; Pauschinger, M; von Scheidt, W1
Carriò, ML; Castro, MJ; Farrero, E; Javierre, C; Lopez-Delgado, JC; Periche, E; Pinseau, A; Rodríguez-Castro, D; Torrado, H; Toscano, JE; Ventura, JL1
Alvaro, G; Amantea, B; Auci, E; Auriemma, S; Baiocchi, M; Bianchi, A; Biondi-Zoccai, G; Bove, T; Bradic, N; Buscaglia, G; Calabrò, MG; Cariello, C; Corcione, A; De Vuono, G; Fominskiy, E; Frontini, M; Galdieri, N; Gemma, M; Gianni, S; Grigoryev, E; Guarracino, F; Landoni, G; Lembo, R; Likhvantsev, V; Lipinski, MJ; Lobreglio, R; Lomivorotov, VV; Monaco, F; Pala, G; Paternoster, G; Pisano, A; Sangalli, F; Wang, CY; Zangrillo, A; Zucchetti, MC1
Mauriat, P; Séguéla, PE; Tafer, N; Thambo, JB1
Anastasiadis, K; Antonitsis, P; Argiriadou, H; Asteriou, C; Grosomanidis, V; Kleontas, A; Tossios, P; Vranis, K1
Almeida, C; Aucouturier, P; Caruba, T; Chatellier, G; Cholley, B; Djadi-Prat, J; Freitas, N; Gomes, N; Hoffart-Jourdain, C; Hourton, D; Menasché, P; Rousseau, D; Sabatier, B; Souag, A; Tibi, A; Yjjou, M1
Altinsoy, HB; Atalay, A; Atalay, H; Azboy, D; Colak, S; Dogan, OF; Temizturk, Z1
Cantinotti, M; Giordano, R; Mannacio, VA; Palma, G1
Boethig, D; Goerler, H; Huber, D; Osthaus, WA; Sasse, M; Sümpelmann, R; Winterhalter, M1
González-Costello, J; Homs, S1
Althabe, M; Balestrini, M; Chang, AC; Charroqui, A; Landry, LM; Lataza, E; Magliola, R; Moreno, G; Salgado, G; Vassallo, JC1
Adanir, T; Aksun, M; Aran, G; Gürbüz, A; Karahan, N; Ozgürbüz, U; Oztürk, T; Sencan, A; Yetkin, U1
Buerke, M; Lemm, H; Russ, M; Schlitt, A; Werdan, K1
Bravo, MC; Bravo, Mdel C; Cabañas, F; López, P; Pellicer, A; Pérez-Fernández, E; Pérez-Rodríguez, J; Quero, J1
Asopa, S; Elahi, MM; Lam, J; Matata, BM1
Läer, S; Vogt, W1
Cogo, PE; Di Chiara, L; Favia, I; Garisto, C; Ricci, Z; Vitale, V1
Freynschlag, R; Gombotz, H; Hofer, A; Lechner, E; Leitner-Peneder, G; Mair, R; Rehak, P; Weinzettel, R1
Algotsson, L; Guarracino, F; Hörmann, C; Knotzer, J; Landoni, G; Lehmann, A; Rajek, A; Salmenperä, M; Schirmer, U; Toller, W; Tritapepe, L; Weis, F1
Caresta, E; Midulla, F; Moretti, C; Papoff, P; Pinto, R; Versacci, P1
Abdalla, M; Cleland, JG; Follath, F; Harjola, VP; Just, H; Lehtonen, L; Mitrovic, V; Papp, JG; Peuhkurinen, K; Sandell, EP; Scholz, H1
Apajasalo, M; Cleland, JG; Kobelt, G; Takala, A; Zethraeus, N1
Nieminen, MS1
Follath, F1
Anifantakis, A; Athanassopoulos, G; Chatzigeorgiou, G; Cokkinos, DV; Iakovis, P; Karatasakis, G; Koutsogiannis, N; Manginas, A; Maounis, T; Papadakis, M; Spargias, KS1
Cavana, M; Fraticelli, A; Mebazaa, A; Pignataro, C1
Mason, P1
Ewert, P; Hetzer, R; Lange, PE; Luther, YC; Mühler, EG; Nasseri, B; Redlin, M; Schulze-Neick, I; Stiller, B1
Amantea, B; Carrata, F; Labriola, C; Santangelo, E; Siro-Brigiani, M1
Ewert, P; Hetzer, R; Lange, PE; Lehmkuhl, HB; Luther, YC; Schulze-Neick, I1
Ng, TM1
Conti, G; De Castro, S; De Luca, L; Di Angelantonio, E; Morelli, A; Orecchioni, A; Pandian, NG; Pietropaoli, P; Rocco, M; Singer, M; Teboul, JL1
Braun, JP; Doepfmer, UR; Dohmen, PM; Jasulaitis, D; Kastrup, M; Konertz, W; Moshirzadeh, M; Spies, C; von Heymann, C1
Bouckaert, Y; Creteur, J; Mélot, C; Vincent, JL1
Delgado, JF1
Alvarez, J; Bouzada, M; Caruezo, V; Fernández, AL; García-Bengoechea, JB; Ginesta, V; González-Juanatey, JR; Rodríguez, J; Rubio, J; Taboada, M1
Al-Shawaf, E; Ayed, A; Dehrab, N; Radomir, B; Tarazi, R; Vislocky, I1
Butt, WW; Crossland, DS; Namachivayam, P; Shekerdemian, LS1
Domínguez-Rodríguez, A; García-González, MJ1
Wessel, DL1
Bröking, K; Ertmer, C; Lange, M; Morelli, A; Rehberg, S; Van Aken, H; Westphal, M1
Brizard, CP; Horton, SB; Mynard, JP; Nørgaard, MA; Penny, DJ; Shekerdemian, LS; Stocker, CF1
Lechner, E; Mair, R; Moosbauer, W; Pinter, M; Tulzer, G1
Bihari, D; Ramaswamykanive, H; Solano, TR1
Antoniou, T; Degiannis, D; Geroulanos, S; Kriaras, I; Papadopoulos, K; Stavridis, G; Tasouli, A1
Adreanides, E; Athanasopoulos, G; Cokkinos, DV; Dritsas, A; Giamouzis, G; Mavrogeni, S; Panagiotakos, D; Papadopoulou, E; Spargias, K; Thomopoulou, S; Vassiliadis, I1
Ghazwinian, N; Hochmair, N; Mueller, T; Plöchl, W; Ponschab, M1
Alvarez, J1
Blanco, N; Botbol, AL; Degrange, MA; del Mazo, CD; Levin, RL; Porcile, R; Salvagio, F; Tanus, E1
Endoh, M1
Laine, M; Lehtonen, L; Nieminen, MS1

Reviews

31 review(s) available for simendan and Cardiac Output, Low

ArticleYear
Effect of Levosimendan Treatment in Pediatric Patients With Cardiac Dysfunction: An Update of a Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Journal of cardiothoracic and vascular anesthesia, 2022, Volume: 36, Issue:3

    Topics: Adolescent; Cardiac Output, Low; Cardiotonic Agents; Child; Humans; Hydrazones; Pyridazines; Randomized Controlled Trials as Topic; Simendan

2022
Levosimendan in paediatric cardiac anaesthesiology: A systematic review and meta-analysis.
    European journal of anaesthesiology, 2022, 08-01, Volume: 39, Issue:8

    Topics: Anesthesiology; Cardiac Output, Low; Cardiotonic Agents; Child; Humans; Hydrazones; Pyridazines; Simendan

2022
Levosimendan and Low Cardiac Output After Cardiac Surgery: Analysis of Trial Data.
    Journal of cardiothoracic and vascular anesthesia, 2023, Volume: 37, Issue:7

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Humans; Hydrazones; Postoperative Complications; Simendan

2023
Levosimendan Reduces Mortality and Low Cardiac Output Syndrome in Cardiac Surgery.
    The Thoracic and cardiovascular surgeon, 2020, Volume: 68, Issue:5

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Heart Disease Risk Factors; Humans; Randomized Controlled Trials as Topic; Risk Assessment; Simendan; Treatment Outcome

2020
Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome.
    The Cochrane database of systematic reviews, 2020, 11-05, Volume: 11

    Topics: Aged; Cardiac Output, Low; Cardiotonic Agents; Cause of Death; Dobutamine; Enoximone; Epinephrine; Humans; Hydrazones; Middle Aged; Myocardial Infarction; Nitric Oxide; Placebos; Pyridazines; Randomized Controlled Trials as Topic; Shock, Cardiogenic; Simendan; Vasodilator Agents

2020
Prophylactic levosimendan for the prevention of low cardiac output syndrome and mortality in paediatric patients undergoing surgery for congenital heart disease.
    The Cochrane database of systematic reviews, 2017, 08-02, Volume: 8

    Topics: Assisted Circulation; Cardiac Output, Low; Cardiotonic Agents; Child, Preschool; Heart Defects, Congenital; Humans; Hydrazones; Infant; Intensive Care Units, Pediatric; Length of Stay; Postoperative Complications; Pyridazines; Randomized Controlled Trials as Topic; Respiration, Artificial; Simendan; Syndrome

2017
Levosimendan for patients with severely reduced left ventricular systolic function and/or low cardiac output syndrome undergoing cardiac surgery: a systematic review and meta-analysis.
    Critical care (London, England), 2017, Oct-19, Volume: 21, Issue:1

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Humans; Hydrazones; Pyridazines; Simendan; Stroke Volume; Ventricular Function, Left

2017
Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome.
    The Cochrane database of systematic reviews, 2018, 01-29, Volume: 1

    Topics: Aged; Cardiac Output, Low; Cardiotonic Agents; Cause of Death; Dobutamine; Enoximone; Humans; Hydrazones; Middle Aged; Myocardial Infarction; Nitric Oxide; Pyridazines; Randomized Controlled Trials as Topic; Shock, Cardiogenic; Simendan; Vasodilator Agents

2018
Levosimendan for Perioperative Cardioprotection: Myth or Reality?
    Current cardiology reviews, 2018, Volume: 14, Issue:3

    Topics: Cardiac Output, Low; Cardiotonic Agents; Humans; Hydrazones; Postoperative Complications; Pyridazines; Retrospective Studies; Simendan

2018
Meta-Analysis of Trials on Prophylactic Use of Levosimendan in Patients Undergoing Cardiac Surgery.
    The Annals of thoracic surgery, 2018, Volume: 105, Issue:5

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Humans; Simendan

2018
Levosimendan versus placebo in cardiac surgery: a systematic review and meta-analysis.
    Interactive cardiovascular and thoracic surgery, 2018, 11-01, Volume: 27, Issue:5

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Humans; Postoperative Complications; Simendan

2018
Effects of levosimendan on mortality in patients undergoing cardiac surgery: A systematic review and meta-analysis.
    Journal of cardiac surgery, 2018, Volume: 33, Issue:6

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Databases, Bibliographic; Humans; Hydrazones; Phosphodiesterase Inhibitors; Postoperative Complications; Pyridazines; Randomized Controlled Trials as Topic; Simendan

2018
Levosimendan in Patients with Left Ventricular Dysfunction Undergoing Cardiac Surgery: An Update Meta-Analysis and Trial Sequential Analysis.
    BioMed research international, 2018, Volume: 2018

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Humans; Hydrazones; Postoperative Complications; Pyridazines; Randomized Controlled Trials as Topic; Renal Replacement Therapy; Simendan; Ventricular Dysfunction, Left

2018
Levosimendan in patients with low cardiac output syndrome undergoing cardiac surgery: A systematic review and meta-analysis.
    Anaesthesia, critical care & pain medicine, 2019, Volume: 38, Issue:3

    Topics: Acute Kidney Injury; Cardiac Output; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Humans; Myocardial Infarction; Odds Ratio; Placebos; Postoperative Complications; Randomized Controlled Trials as Topic; Simendan; Time Factors

2019
Inotropic agents and vasodilator strategies for acute myocardial infarction complicated by cardiogenic shock or low cardiac output syndrome.
    The Cochrane database of systematic reviews, 2014, Jan-02, Issue:1

    Topics: Cardiac Output, Low; Cardiotonic Agents; Dobutamine; Enoximone; Humans; Hydrazones; Myocardial Infarction; Nitric Oxide; Pyridazines; Randomized Controlled Trials as Topic; Shock, Cardiogenic; Simendan; Vasodilator Agents

2014
Effects of levosimendan for low cardiac output syndrome in critically ill patients: systematic review with meta-analysis and trial sequential analysis.
    Intensive care medicine, 2015, Volume: 41, Issue:2

    Topics: Cardiac Output, Low; Cardiotonic Agents; Critical Illness; Humans; Hydrazones; Pyridazines; Simendan; Treatment Outcome

2015
Prophylactic milrinone for the prevention of low cardiac output syndrome and mortality in children undergoing surgery for congenital heart disease.
    The Cochrane database of systematic reviews, 2015, Mar-25, Issue:3

    Topics: Cardiac Output, Low; Cardiotonic Agents; Dobutamine; Heart Defects, Congenital; Humans; Hydrazones; Infant; Infant, Newborn; Milrinone; Postoperative Complications; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Syndrome; Time Factors

2015
Levosimendan Reduces Mortality in Adults with Left Ventricular Dysfunction Undergoing Cardiac Surgery: A Systematic Review and Meta-analysis.
    Journal of cardiac surgery, 2015, Volume: 30, Issue:7

    Topics: Acute Kidney Injury; Adult; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Databases, Bibliographic; Humans; Hydrazones; Postoperative Complications; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Ventricular Dysfunction, Left

2015
Inodilators in the Management of Low Cardiac Output Syndrome After Pediatric Cardiac Surgery.
    Current vascular pharmacology, 2016, Volume: 14, Issue:1

    Topics: Animals; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Child; Humans; Hydrazones; Milrinone; Phosphodiesterase Inhibitors; Pyridazines; Simendan; Vasodilator Agents

2016
Long-term intravenous inotropes in low-output terminal heart failure?
    Clinical research in cardiology : official journal of the German Cardiac Society, 2016, Volume: 105, Issue:6

    Topics: Administration, Intravenous; Cardiac Output; Cardiac Output, Low; Cardiotonic Agents; Chi-Square Distribution; Dobutamine; Drug Administration Schedule; Heart Failure; Heart Transplantation; Humans; Hydrazones; Milrinone; Odds Ratio; Practice Guidelines as Topic; Pyridazines; Risk Factors; Simendan; Time Factors; Treatment Outcome; Waiting Lists

2016
[Use of levosimendan in children].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2016, Volume: 23, Issue:8

    Topics: Cardiac Output, Low; Cardiotonic Agents; Child; Extracorporeal Circulation; Heart Failure; Humans; Hydrazones; Postoperative Complications; Pyridazines; Simendan

2016
Prophylactic levosimendan for the prevention of low cardiac output syndrome and mortality in paediatric patients undergoing surgery for congenital heart disease.
    The Cochrane database of systematic reviews, 2017, Mar-06, Volume: 3

    Topics: Assisted Circulation; Cardiac Output, Low; Cardiotonic Agents; Coronary Care Units; Heart Defects, Congenital; Humans; Hydrazones; Length of Stay; Postoperative Complications; Pyridazines; Randomized Controlled Trials as Topic; Respiration, Artificial; Simendan

2017
[Therapeutic strategies in acute decompensated heart failure and cardiogenic shock].
    Der Internist, 2010, Volume: 51, Issue:8

    Topics: Aged; Cardiac Output, Low; Cardiotonic Agents; Combined Modality Therapy; Comorbidity; Critical Care; Cross-Sectional Studies; Diuretics; Emergency Service, Hospital; Heart Failure; Hospitalization; Humans; Hydrazones; Multicenter Studies as Topic; Myocardial Revascularization; Population Dynamics; Pyridazines; Risk Factors; Shock, Cardiogenic; Simendan; Vasodilator Agents

2010
Levosimendan versus an intra-aortic balloon pump in adult cardiac surgery patients with low cardiac output.
    Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:6

    Topics: Algorithms; Cardiac Output; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Humans; Hydrazones; Intra-Aortic Balloon Pumping; Myocardial Stunning; Preoperative Care; Pyridazines; Randomized Controlled Trials as Topic; Risk Assessment; Simendan

2011
Perioperative use of levosimendan: best practice in operative settings.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:2

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Critical Illness; Humans; Hydrazones; Perioperative Care; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Surgical Procedures, Operative

2013
The clinical experience with levosimendan in anesthesiology and in the intensive care unit.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2003, Volume: 4 Suppl 2

    Topics: Adrenergic beta-Antagonists; Anesthesia; Calcium Channels, L-Type; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Heart Failure; Humans; Hydrazones; Intensive Care Units; Myocardial Contraction; Pyridazines; Shock, Cardiogenic; Simendan; Systole; Ventricular Dysfunction, Left

2003
Levosimendan.
    Intensive & critical care nursing, 2003, Volume: 19, Issue:6

    Topics: Cardiac Output, Low; Cardiotonic Agents; Humans; Hydrazones; Pyridazines; Simendan

2003
Levosimendan, a new calcium-sensitizing inotrope for heart failure.
    Pharmacotherapy, 2004, Volume: 24, Issue:10

    Topics: Animals; Calcium; Cardiac Output, Low; Cardiotonic Agents; Clinical Trials as Topic; Humans; Hydrazones; Myocardial Contraction; Pyridazines; Simendan; Treatment Outcome

2004
[Levosimendan in acute heart failure: past, present and future].
    Revista espanola de cardiologia, 2006, Volume: 59, Issue:4

    Topics: Acute Disease; Cardiac Output, Low; Cardiotonic Agents; Clinical Trials as Topic; Forecasting; Humans; Hydrazones; Pyridazines; Simendan

2006
[Role of Levosimendan in intensive care treatment of myocardial insufficiency].
    Der Anaesthesist, 2007, Volume: 56, Issue:1

    Topics: Calcium; Cardiac Output, Low; Cardiotonic Agents; Critical Care; Humans; Hydrazones; Myocardial Ischemia; Postoperative Care; Pyridazines; Simendan

2007
Mechanism of action of Ca2+ sensitizers--update 2001.
    Cardiovascular drugs and therapy, 2001, Volume: 15, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Calcium; Calcium Signaling; Cardiac Output, Low; Cardiotonic Agents; Hemodynamics; Humans; Hydrazones; Myocardial Contraction; Pyridazines; Simendan

2001

Trials

27 trial(s) available for simendan and Cardiac Output, Low

ArticleYear
[Levosimendan for preventing low output syndrome in pediatric patients with correction of tetralogy of Fallot].
    Revista medica del Instituto Mexicano del Seguro Social, 2022, May-02, Volume: 60, Issue:3

    Topics: Cardiac Output, Low; Cardiotonic Agents; Child; Humans; Hydrazones; Longitudinal Studies; Milrinone; Prospective Studies; Pyridazines; Simendan; Syndrome; Tetralogy of Fallot

2022
Predictors and associated clinical outcomes of low cardiac output syndrome following cardiac surgery: insights from the LEVO-CTS trial.
    European heart journal. Acute cardiovascular care, 2022, Nov-30, Volume: 11, Issue:11

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Humans; Hydrazones; Postoperative Complications; Pyridazines; Simendan; Ventricular Dysfunction, Left

2022
Preservation of renal function in cardiac surgery patients with low cardiac output syndrome: levosimendan vs beta agonists.
    BMC anesthesiology, 2019, 11-17, Volume: 19, Issue:1

    Topics: Adrenergic beta-Agonists; Aged; Aged, 80 and over; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Female; Humans; Incidence; Male; Middle Aged; Postoperative Complications; Renal Insufficiency; Simendan

2019
Prophylactic use of levosimendan in pediatric patients undergoing cardiac surgery: a prospective randomized controlled trial.
    Critical care (London, England), 2019, 12-30, Volume: 23, Issue:1

    Topics: Biomarkers; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cardiotonic Agents; Child, Preschool; Double-Blind Method; Female; Heart Defects, Congenital; Hemodynamics; Humans; Incidence; Infant; Kaplan-Meier Estimate; Length of Stay; Male; Postoperative Complications; Prospective Studies; Respiration, Artificial; Simendan; Treatment Outcome

2019
Long-term outcome of perioperative low cardiac output syndrome in cardiac surgery: 1-year results of a multicenter randomized trial.
    Journal of critical care, 2020, Volume: 58

    Topics: Age Factors; Cardiac Output, Low; Cardiotonic Agents; Cardiovascular Surgical Procedures; Double-Blind Method; Female; Humans; Male; Middle Aged; Postoperative Complications; Simendan; Survival Analysis; Treatment Outcome

2020
Levosimendan in Patients with Left Ventricular Dysfunction Undergoing Cardiac Surgery.
    The New England journal of medicine, 2017, 05-25, Volume: 376, Issue:21

    Topics: Aged; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Double-Blind Method; Female; Heart-Assist Devices; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Mortality; Myocardial Infarction; Perioperative Period; Postoperative Complications; Pyridazines; Renal Replacement Therapy; Simendan; Stroke Volume; Treatment Failure; Ventricular Dysfunction, Left

2017
Levosimendan for Hemodynamic Support after Cardiac Surgery.
    The New England journal of medicine, 2017, 05-25, Volume: 376, Issue:21

    Topics: Aged; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Double-Blind Method; Female; Hemodynamics; Humans; Hydrazones; Infusions, Intravenous; Length of Stay; Male; Middle Aged; Mortality; Perioperative Period; Postoperative Complications; Pyridazines; Respiration, Artificial; Simendan; Stroke Volume; Treatment Failure

2017
Effect of Levosimendan on Low Cardiac Output Syndrome in Patients With Low Ejection Fraction Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass: The LICORN Randomized Clinical Trial.
    JAMA, 2017, 08-08, Volume: 318, Issue:6

    Topics: Aged; Cardiac Output, Low; Cardiopulmonary Bypass; Cardiotonic Agents; Catecholamines; Coronary Artery Bypass; Double-Blind Method; Female; Heart-Assist Devices; Humans; Hydrazones; Infusions, Intravenous; Intention to Treat Analysis; Male; Middle Aged; Postoperative Complications; Premedication; Pyridazines; Renal Replacement Therapy; Simendan; Stroke Volume; Treatment Failure

2017
PREVENTION OF HEART FAILURE PATIENTS WITH DECREASED EJECTION FRACTION IN NON-CARDIAC SURGERY: LEVOSIMENDAN OR ANESTHETIC CARDIOPROTECTION?.
    Anesteziologiia i reanimatologiia, 2016, Volume: 61, Issue:6

    Topics: Aged; Anesthesia, General; Aorta; Cardiac Output, Low; Cardiopulmonary Bypass; Cardiotonic Agents; Female; Heart Failure; Humans; Hydrazones; Male; Perioperative Period; Prospective Studies; Pyridazines; Retrospective Studies; Simendan; Treatment Outcome

2016
A comparison of dobutamine and levosimendan on hepatic blood flow in patients with a low cardiac output state after cardiac surgery: a randomised controlled study.
    Anaesthesia and intensive care, 2013, Volume: 41, Issue:6

    Topics: Aged; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Dobutamine; Female; Hemodynamics; Humans; Hydrazones; Liver Circulation; Male; Postoperative Complications; Pyridazines; Simendan; Vascular Resistance

2013
A randomized controlled trial of levosimendan to reduce mortality in high-risk cardiac surgery patients (CHEETAH): Rationale and design.
    American heart journal, 2016, Volume: 177

    Topics: Acute Kidney Injury; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Double-Blind Method; Humans; Hydrazones; Infusions, Intravenous; Intensive Care Units; Intra-Aortic Balloon Pumping; Length of Stay; Postoperative Complications; Pyridazines; Respiration, Artificial; Simendan

2016
Effectiveness of prophylactic levosimendan in patients with impaired left ventricular function undergoing coronary artery bypass grafting: a randomized pilot study.
    Interactive cardiovascular and thoracic surgery, 2016, Volume: 23, Issue:5

    Topics: Cardiac Output, Low; Cardiotonic Agents; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Female; Finland; Follow-Up Studies; Humans; Hydrazones; Incidence; Infusions, Intravenous; Male; Middle Aged; Pilot Projects; Postoperative Complications; Prospective Studies; Pyridazines; Simendan; Stroke Volume; Survival Rate; Tomography, Emission-Computed, Single-Photon; Ventricular Dysfunction, Left; Ventricular Function, Left

2016
Rationale and design of the multicenter randomized trial investigating the effects of levosimendan pretreatment in patients with low ejection fraction (≤40 %) undergoing CABG with cardiopulmonary bypass (LICORN study).
    Journal of cardiothoracic surgery, 2016, Aug-05, Volume: 11, Issue:1

    Topics: Cardiac Output, Low; Cardiopulmonary Bypass; Cardiotonic Agents; Coronary Artery Bypass; Double-Blind Method; Heart-Assist Devices; Humans; Hydrazones; Perioperative Period; Pyridazines; Renal Replacement Therapy; Research Design; Simendan; Stroke Volume; Ventricular Dysfunction, Left

2016
[Levosimendan, a new inotropic drug: experience in children with acute heart failure].
    Archivos argentinos de pediatria, 2009, Volume: 107, Issue:2

    Topics: Acute Disease; Adolescent; Cardiac Output, Low; Cardiotonic Agents; Child; Child, Preschool; Female; Humans; Hydrazones; Infant; Male; Prospective Studies; Pyridazines; Simendan

2009
Levosimendan infusion in newborns after corrective surgery for congenital heart disease: randomized controlled trial.
    Intensive care medicine, 2012, Volume: 38, Issue:7

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Heart Defects, Congenital; Humans; Hydrazones; Infant, Newborn; Infusions, Intravenous; Italy; Outcome Assessment, Health Care; Postoperative Complications; Pyridazines; Simendan

2012
Levosimendan versus milrinone in neonates and infants after corrective open-heart surgery: a pilot study.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2012, Volume: 13, Issue:5

    Topics: Analysis of Variance; Body Surface Area; Cardiac Output; Cardiac Output, Low; Cardiopulmonary Bypass; Cardiotonic Agents; Double-Blind Method; Female; Heart Defects, Congenital; Humans; Hydrazones; Infant; Infant, Newborn; Intention to Treat Analysis; Male; Milrinone; Pilot Projects; Premedication; Pyridazines; Simendan; Statistics, Nonparametric

2012
Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial.
    Lancet (London, England), 2002, Jul-20, Volume: 360, Issue:9328

    Topics: Cardiac Output, Low; Cardiotonic Agents; Dobutamine; Double-Blind Method; Female; Hemodynamics; Humans; Hydrazones; Male; Middle Aged; Pyridazines; Simendan; Treatment Outcome

2002
Intravenous levosimendan treatment is cost-effective compared with dobutamine in severe low-output heart failure: an analysis based on the international LIDO trial.
    European journal of heart failure, 2003, Volume: 5, Issue:1

    Topics: Aged; Cardiac Output, Low; Cardiotonic Agents; Cost-Benefit Analysis; Dobutamine; Double-Blind Method; Europe; Female; Follow-Up Studies; Heart Failure; Humans; Hydrazones; Infusions, Intravenous; Length of Stay; Life Expectancy; Male; Middle Aged; Patient Admission; Pyridazines; Randomized Controlled Trials as Topic; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Simendan; Survival Analysis; Treatment Outcome

2003
Levosimendan compared with dobutamine in low output patients.
    Minerva anestesiologica, 2003, Volume: 69, Issue:4

    Topics: Cardiac Output, Low; Cardiotonic Agents; Dobutamine; Double-Blind Method; Hemodynamics; Humans; Hydrazones; Pulmonary Wedge Pressure; Pyridazines; Simendan

2003
Levosimendan in patients with low-output heart failure: lessons from the LIDO trial.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2003, Volume: 4 Suppl 2

    Topics: Adrenergic beta-Agonists; Calcium Channels, L-Type; Cardiac Output, Low; Cardiotonic Agents; Death, Sudden, Cardiac; Dobutamine; Dose-Response Relationship, Drug; Double-Blind Method; Europe; Heart Failure; Heart Rate; Humans; Hydrazones; Infusions, Intravenous; Morbidity; Myocardial Contraction; Pulmonary Wedge Pressure; Pyridazines; Risk Factors; Severity of Illness Index; Shock, Cardiogenic; Simendan; Stroke Volume; Survival Analysis; Time; Treatment Outcome; Vasodilator Agents; Ventricular Dysfunction, Left

2003
Hemodynamic effects of levosimendan in patients with low-output heart failure after cardiac surgery.
    International journal of clinical pharmacology and therapeutics, 2004, Volume: 42, Issue:4

    Topics: Aged; Aged, 80 and over; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Female; Hemodynamics; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Pyridazines; Simendan

2004
Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression.
    Intensive care medicine, 2005, Volume: 31, Issue:5

    Topics: Cardiac Output, Low; Cardiotonic Agents; Female; Gastric Mucosa; Hemodynamics; Humans; Hydrazones; Male; Middle Aged; Pyridazines; Shock, Septic; Simendan; Statistics, Nonparametric

2005
[Hemodynamic effects of levosimendan compared with dobutamine in patients with low cardiac output after cardiac surgery].
    Revista espanola de cardiologia, 2006, Volume: 59, Issue:4

    Topics: Aged; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Dobutamine; Female; Hemodynamics; Humans; Hydrazones; Male; Prospective Studies; Pyridazines; Simendan

2006
Levosimendan or milrinone in the type 2 diabetic patient with low ejection fraction undergoing elective coronary artery surgery.
    Journal of cardiothoracic and vascular anesthesia, 2006, Volume: 20, Issue:3

    Topics: Adult; Aged; Blood Pressure; Cardiac Output, Low; Cardiopulmonary Bypass; Coronary Artery Bypass; Diabetes Mellitus, Type 2; Elective Surgical Procedures; Female; Humans; Hydrazones; Male; Middle Aged; Milrinone; Phosphodiesterase Inhibitors; Pyridazines; Simendan; Stroke Volume; Vascular Resistance

2006
Efficacy and safety of perioperative infusion of levosimendan in patients with compromised cardiac function undergoing open-heart surgery: importance of early use.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2007, Volume: 32, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Cardiac Output, Low; Cardiopulmonary Bypass; Cardiotonic Agents; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Hydrazones; Intraoperative Complications; Male; Middle Aged; Pyridazines; Simendan; Syndrome; Treatment Outcome

2007
A 6-month follow-up of intermittent levosimendan administration effect on systolic function, specific activity questionnaire, and arrhythmia in advanced heart failure.
    Journal of cardiac failure, 2007, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Output, Low; Cardiotonic Agents; Drug Administration Schedule; Echocardiography; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Hydrazones; Middle Aged; Mitral Valve Insufficiency; Myocardial Contraction; Pyridazines; Simendan; Stroke Volume; Surveys and Questionnaires; Systole; Ventricular Dysfunction, Left; Ventricular Function, Left

2007
[The calcium sensitizer levosimendan gives superior results to dobutamine in postoperative low cardiac output syndrome].
    Revista espanola de cardiologia, 2008, Volume: 61, Issue:5

    Topics: Cardiac Output, Low; Cardiotonic Agents; Dobutamine; Female; Humans; Hydrazones; Male; Middle Aged; Postoperative Complications; Prospective Studies; Pyridazines; Simendan

2008

Other Studies

40 other study(ies) available for simendan and Cardiac Output, Low

ArticleYear
Take It or Levo It: An Updated Look at the Use of Levosimendan to Prevent Low Cardiac Output Syndrome in Pediatric Patients.
    Journal of cardiothoracic and vascular anesthesia, 2022, Volume: 36, Issue:3

    Topics: Cardiac Output, Low; Child; Humans; Hydrazones; Pyridazines; Simendan

2022
Evaluation of levosimendan as treatment option in a large case-series of preterm infants with cardiac dysfunction and pulmonary hypertension.
    European journal of pediatrics, 2023, Volume: 182, Issue:7

    Topics: Adult; Calcium; Cardiac Output, Low; Cardiotonic Agents; Child; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Infant, Premature; Lactates; Simendan; Ventricular Dysfunction, Left

2023
Effects of levosimendan on ventriculo-arterial coupling and cardiac efficiency in paediatric patients with single-ventricle physiology after surgical palliation: retrospective study.
    Interactive cardiovascular and thoracic surgery, 2020, 04-01, Volume: 30, Issue:4

    Topics: Cardiac Output, Low; Cardiotonic Agents; Echocardiography; Female; Heart Failure; Humans; Hypoplastic Left Heart Syndrome; Infant; Infant, Newborn; Male; Retrospective Studies; Simendan; Stroke Volume; Univentricular Heart; Ventricular Function, Left

2020
Prophylactic use of levosimendan in pediatric patients undergoing cardiac surgery: the jury is still out.
    Critical care (London, England), 2020, 03-23, Volume: 24, Issue:1

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Child; Humans; Prospective Studies; Simendan

2020
Preconditioning with levosimendan reduces postoperative low cardiac output in moderate-severe systolic dysfunction patients who will undergo elective coronary artery bypass graft surgery: a cost-effective strategy.
    Journal of cardiothoracic surgery, 2020, May-24, Volume: 15, Issue:1

    Topics: Aged; Cardiac Output, Low; Cardiotonic Agents; Coronary Artery Bypass; Coronary Artery Disease; Cost-Benefit Analysis; Elective Surgical Procedures; Female; Humans; Incidence; Male; Postoperative Complications; Simendan; Spain; Stroke Volume; Ventricular Function, Left

2020
[Individualized use of levosimendan in cardiac surgery].
    Der Anaesthesist, 2021, Volume: 70, Issue:3

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Humans; Hydrazones; Postoperative Complications; Pyridazines; Retrospective Studies; Simendan; Stroke Volume; Ventricular Function, Left

2021
A Randomized Porcine Study in Low Cardiac Output of Vasoactive and Inotropic Drug Effects on the Gastrointestinal Tract.
    Shock (Augusta, Ga.), 2021, 08-01, Volume: 56, Issue:2

    Topics: Animals; Cardiac Output, Low; Disease Models, Animal; Female; Gastrointestinal Tract; Male; Milrinone; Norepinephrine; Random Allocation; Simendan; Splanchnic Circulation; Swine; Vasodilator Agents; Vasopressins

2021
Levosimendan or dobutamine in patients with low cardiac output syndrome: Results from meta-analysis.
    International journal of cardiology, 2021, 06-15, Volume: 333

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Dobutamine; Humans; Hydrazones; Pyridazines; Simendan

2021
Reply to: Levosimendan or dobutamine in patients with low cardiac output syndrome: Results from meta-analysis.
    International journal of cardiology, 2021, 08-01, Volume: 336

    Topics: Cardiac Output, Low; Dobutamine; Humans; Hydrazones; Pyridazines; Simendan

2021
Levosimendan for the Low Cardiac Output Syndrome after Cardiac Surgery.
    The New England journal of medicine, 2017, 05-25, Volume: 376, Issue:21

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Humans; Hydrazones; Pyridazines; Simendan

2017
Is There Still Room for the Prophylactic Use of Levosimendan in Cardiac Surgery?
    The Annals of thoracic surgery, 2018, Volume: 106, Issue:5

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Humans; Simendan

2018
Should we still prescribe Levosimendan for low cardiac output after cardiac surgery? Perhaps in the good patients!
    Anaesthesia, critical care & pain medicine, 2019, Volume: 38, Issue:3

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Humans; Hydrazones; Simendan

2019
CON: Levosimendan should be used in clinical practice for patients with significantly impaired left ventricular function undergoing cardiac surgery.
    Anaesthesia, critical care & pain medicine, 2019, Volume: 38, Issue:3

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Humans; Hydrazones; Simendan; Ventricular Function, Left

2019
Should we keep levosimendan in our pharmacies? Yes, undoubtedly!
    Anaesthesia, critical care & pain medicine, 2019, Volume: 38, Issue:3

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Humans; Hydrazones; Pharmacies; Pyridazines; Simendan

2019
[Application of levosimendan in acute heart failure patients with symptoms of low cardiac output: case series report].
    Kardiologia polska, 2013, Volume: 71, Issue:3

    Topics: Adult; Aged; Cardiac Output, Low; Cardiotonic Agents; Heart Failure; Hemodynamics; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Pyridazines; Simendan

2013
[Pilot study of levosimendan : Effect on liver blood flow and liver function in acute decompensated heart failure].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2014, Volume: 109, Issue:4

    Topics: Adult; Aged; Cardiac Output, Low; Cardiotonic Agents; Female; Heart Failure; Hemodynamics; Humans; Hydrazones; Indocyanine Green; Infusions, Intravenous; Liver; Liver Failure; Liver Function Tests; Male; Middle Aged; Pilot Projects; Pyridazines; Regional Blood Flow; Simendan

2014
Early levosimendan administration is associated with decreased mortality after cardiac surgery.
    Journal of critical care, 2015, Volume: 30, Issue:4

    Topics: Aged; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Coronary Artery Bypass; Female; Heart Valve Prosthesis Implantation; Hospital Mortality; Humans; Hydrazones; Intensive Care Units; Logistic Models; Male; Middle Aged; Odds Ratio; Postoperative Complications; Proportional Hazards Models; Pyridazines; Renal Insufficiency; Renal Replacement Therapy; Retrospective Studies; Simendan; Stroke Volume; Survival Rate; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left

2015
Five-year mortality in cardiac surgery patients with low cardiac output syndrome treated with levosimendan: prognostic evaluation of NT-proBNP and C-reactive protein.
    Minerva cardioangiologica, 2016, Volume: 64, Issue:2

    Topics: Aged; C-Reactive Protein; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Female; Follow-Up Studies; Humans; Hydrazones; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Prognosis; Proportional Hazards Models; Prospective Studies; Pyridazines; Risk Factors; Simendan; Time Factors; Treatment Outcome

2016
Levosimendan Use Increases Cardiac Performance after Coronary Artery Bypass Grafting in End-Stage Renal Disease Patients.
    The heart surgery forum, 2016, Oct-27, Volume: 19, Issue:5

    Topics: Aged; Cardiac Output, Low; Coronary Artery Bypass; Female; Hemodynamics; Humans; Hydrazones; Kidney Failure, Chronic; Male; Middle Aged; Postoperative Complications; Preoperative Care; Pyridazines; Simendan; Vasodilator Agents

2016
First Experience With Levosimendan Therapy After Correction of Congenital Heart Disease.
    Journal of cardiothoracic and vascular anesthesia, 2017, Volume: 31, Issue:1

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Child; Child, Preschool; Female; Heart Defects, Congenital; Hemodynamics; Humans; Hydrazones; Infant; Infusions, Intravenous; Male; Postoperative Care; Pyridazines; Simendan

2017
First experiences with intraoperative Levosimendan in pediatric cardiac surgery.
    European journal of pediatrics, 2009, Volume: 168, Issue:6

    Topics: Cardiac Output; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Heart; Heart Defects, Congenital; Hemodynamics; Humans; Hydrazones; Infant; Infant, Newborn; Infusions, Intravenous; Intraoperative Period; Lactic Acid; Length of Stay; Oxygen; Postoperative Complications; Pyridazines; Respiration, Artificial; Retrospective Studies; Simendan; Transposition of Great Vessels

2009
[Superiority of levosimendan to dobutamine in postoperative low cardiac output syndrome: is it due to previous beta-blocker treatment?].
    Revista espanola de cardiologia, 2008, Volume: 61, Issue:11

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cardiac Output, Low; Dobutamine; Drug Interactions; Humans; Hydrazones; Length of Stay; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Vasodilator Agents

2008
Timing of levosimendan in cardiac surgery.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2009, Volume: 9, Issue:3

    Topics: Aged; Cardiac Output, Low; Cardiotonic Agents; Drug Administration Schedule; Female; Hemodynamics; Humans; Hydrazones; Intraoperative Care; Male; Middle Aged; Myocardial Contraction; Patient Selection; Postoperative Care; Pyridazines; Retrospective Studies; Simendan; Time Factors; Ventricular Dysfunction, Left

2009
Acute effects of levosimendan on cerebral and systemic perfusion and oxygenation in newborns: an observational study.
    Neonatology, 2011, Volume: 99, Issue:3

    Topics: Blood Pressure; Cardiac Output, Low; Cardiotonic Agents; Cerebrovascular Circulation; Heart Defects, Congenital; Heart Rate; Hemoglobins; Humans; Hydrazones; Infant, Newborn; Lactic Acid; Prospective Studies; Pyridazines; Respiration; Simendan; Statistics, Nonparametric

2011
Prevention for pediatric low cardiac output syndrome: results from the European survey EuLoCOS-Paed.
    Paediatric anaesthesia, 2011, Volume: 21, Issue:12

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Child, Preschool; Dobutamine; Dopamine; Drug Therapy, Combination; Epinephrine; Europe; Health Care Surveys; Hospitals; Humans; Hydrazones; Infant; Milrinone; Pediatrics; Practice Patterns, Physicians'; Pyridazines; Simendan; Surveys and Questionnaires

2011
Beneficial effects of levosimendan in infants with sepsis-associated cardiac dysfunction: report of 2 cases.
    Pediatric emergency care, 2012, Volume: 28, Issue:10

    Topics: Cardiac Output; Cardiac Output, Low; Cardiotonic Agents; Humans; Hydrazones; Infant; Infusions, Intravenous; Male; Myocardial Contraction; Pyridazines; Shock, Septic; Simendan

2012
Preliminary clinical experience with the repetitive administration of levosimendan in patients with end-stage heart failure.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2003, Volume: 4 Suppl 2

    Topics: Adolescent; Adult; Aged; Biomarkers; Blood Pressure; Calcium Channels, L-Type; Cardiac Output, Low; Cardiotonic Agents; Diastole; Dobutamine; Dopamine; Drug Therapy, Combination; Echocardiography; Electrocardiography; Female; Follow-Up Studies; Greece; Heart Failure; Heart Ventricles; Hematocrit; Hemoglobins; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Myocardial Contraction; Potassium; Pyridazines; Severity of Illness Index; Simendan; Stimulation, Chemical; Survival Analysis; Systole; Treatment Outcome; Ventricular Dysfunction, Left

2003
[Levosimendan-long-term inodilation in an infant with myocardial infarction].
    Zeitschrift fur Kardiologie, 2004, Volume: 93, Issue:3

    Topics: Cardiac Output, Low; Cardiotonic Agents; Coronary Stenosis; Coronary Vessel Anomalies; Echocardiography, Doppler; Electrocardiography, Ambulatory; Humans; Hydrazones; Hypertension, Pulmonary; Infant; Infant, Newborn; Long-Term Care; Male; Myocardial Infarction; Postoperative Complications; Pulmonary Artery; Pulmonary Wedge Pressure; Pyridazines; Simendan; Stroke Volume; Treatment Outcome; Vascular Resistance; Vasodilator Agents

2004
End-stage heart failure with pulmonary hypertension: levosimendan to evaluate for heart transplantation alone versus combined heart-lung transplantation.
    Transplantation, 2004, Oct-27, Volume: 78, Issue:8

    Topics: Adolescent; Cardiac Output, Low; Cardiotonic Agents; Heart Transplantation; Heart-Lung Transplantation; Humans; Hydrazones; Hypertension, Pulmonary; Male; Pyridazines; Simendan

2004
Levosimendan may improve survival in patients requiring mechanical assist devices for post-cardiotomy heart failure.
    Critical care (London, England), 2006, Volume: 10, Issue:1

    Topics: Aged; Cardiac Output, Low; Cardiac Surgical Procedures; Female; Heart-Assist Devices; Humans; Hydrazones; Intensive Care Units; Male; Middle Aged; Postoperative Complications; Pyridazines; Retrospective Studies; Simendan; Survival Rate; Vasodilator Agents

2006
Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression.
    Intensive care medicine, 2006, Volume: 32, Issue:5

    Topics: Belgium; Cardiac Output, Low; Humans; Hydrazones; Pyridazines; Shock, Septic; Simendan; Vasodilator Agents

2006
Early experience with Levosimendan in children with ventricular dysfunction.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2006, Volume: 7, Issue:5

    Topics: Adolescent; Cardiac Output, Low; Cardiotonic Agents; Catecholamines; Child; Child, Preschool; Cohort Studies; Critical Illness; Humans; Hydrazones; Infant; Infant, Newborn; Intensive Care Units, Pediatric; Pyridazines; Retrospective Studies; Simendan; Stroke Volume; Ultrasonography; Ventricular Dysfunction

2006
[Effect of levosimendan treatment of myocardial stunning and low-output syndrome after cardiac surgery].
    Revista espanola de cardiologia, 2006, Volume: 59, Issue:8

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Humans; Hydrazones; Myocardial Stunning; Pyridazines; Simendan

2006
Testing new drugs for heart failure in children.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2006, Volume: 7, Issue:5

    Topics: Adolescent; Cardiac Output, Low; Cardiotonic Agents; Catecholamines; Child; Child, Preschool; Humans; Hydrazones; Infant; Milrinone; Pyridazines; Simendan

2006
Mechanisms of a reduced cardiac output and the effects of milrinone and levosimendan in a model of infant cardiopulmonary bypass.
    Critical care medicine, 2007, Volume: 35, Issue:1

    Topics: Age Factors; Animals; Cardiac Output; Cardiac Output, Low; Cardiopulmonary Bypass; Cardiotonic Agents; Diastole; Disease Models, Animal; Drug Evaluation, Preclinical; Heart Rate; Humans; Hydrazones; Infant; Milrinone; Oxygen Consumption; Pulmonary Gas Exchange; Pyridazines; Risk Factors; Simendan; Swine; Time Factors; Vascular Resistance; Ventricular Function, Left

2007
Use of levosimendan, a new inodilator, for postoperative myocardial stunning in a premature neonate.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2007, Volume: 8, Issue:1

    Topics: Cardiac Output, Low; Cardiotonic Agents; Echocardiography; Follow-Up Studies; Gestational Age; Heart Failure; Humans; Hydrazones; Infant; Infant, Newborn; Infant, Premature, Diseases; Intensive Care Units, Pediatric; Male; Myocardial Stunning; Postoperative Complications; Pyridazines; Simendan; Time Factors; Transposition of Great Vessels; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Function, Left

2007
Myocardial depression associated with pneumococcal septic shock reversed by levosimendan.
    Anaesthesia and intensive care, 2007, Volume: 35, Issue:3

    Topics: Aged; Cardiac Output, Low; Female; Humans; Hydrazones; Pneumococcal Infections; Pyridazines; Shock, Septic; Simendan; Vasodilator Agents

2007
Levosimendan infusion improves haemodynamics in elderly heart failure patients undergoing urgent hip fracture repair.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:8

    Topics: Aged; Aged, 80 and over; Cardiac Output, Low; Cardiotonic Agents; Emergencies; Female; Heart Failure; Hemodynamics; Hip Fractures; Humans; Hydrazones; Infusions, Intravenous; Male; Natriuretic Peptides; Patient Selection; Preoperative Care; Pyridazines; Simendan; Survival Rate; Time Factors; Treatment Outcome; Troponin

2008
[Levosimendan and low cardiac output syndrome. Does mortality really decrease? ].
    Revista espanola de cardiologia, 2008, Volume: 61, Issue:5

    Topics: Cardiac Output, Low; Cardiotonic Agents; Humans; Hydrazones; Pyridazines; Simendan

2008
[Calcium sensitizers--a new group of drugs that increase myocardium contractility].
    Duodecim; laaketieteellinen aikakauskirja, 2000, Volume: 116, Issue:20

    Topics: Animals; Calcium; Cardiac Output, Low; Cardiotonic Agents; Clinical Trials as Topic; Heart; Heart Failure; Humans; Hydrazones; Myocardial Contraction; Pyridazines; Simendan; Ventricular Function, Left

2000