Page last updated: 2024-08-24

simendan and Cardiac Diseases

simendan has been researched along with Cardiac Diseases in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's8 (61.54)24.3611
2020's4 (30.77)2.80

Authors

AuthorsStudies
Chen, J; Chen, WT; Lei, YY; Lin, XF; Liu, DH; Liu, YY; Ning, YL; Xian, SX; Yang, ZQ1
Cheng, Q; Guo, J; Zhang, X; Zhu, Y1
Burton, F; Dietrichs, ES; Ghasemi, M; Selli, AL; Smith, G; Watters, T1
Al-Beidh, F; Antcliffe, DB; Ashby, D; Cross, M; Gordon, AC; Mason, AJ; McAuley, DF; O'Dea, K; Orme, RML; Perkins, GD; Santhakumaran, S; Singer, M; Ward, JK1
Bettex, D; Bouchez, S; Cholley, B; Guarracino, F; Heringlake, M; Kivikko, M; Lomivorotov, VV; Pollesello, P; Rajek, A1
Gao, X; Hu, C; Liu, P; Sun, L; Wang, Y; Xu, Z; Zhang, Y; Zhou, X1
Huo, JH; Luo, X; Qiang, H; Wang, ZQ1
Andreadou, I; Chavdoula, E; Cokkinos, DV; Davos, CH; Efentakis, P; Farmakis, D; Gioti, K; Iliodromitis, EK; Klinakis, A; Kostomitsopoulos, N; Papapetropoulos, A; Sanoudou, D; Sigala, F; Suter, T; Tasouli, A; Tenta, R; Varela, A; Wenzel, P1
Harjola, VP; Kivikko, M; Parissis, J; Pollesello, P1
Bignami, E; Biondi-Zoccai, G; Bruno, G; Corno, L; Gerli, C; Landoni, G; Mizzi, A; Zambon, M; Zangrillo, A1
Boboshko, VA; Cherniavskiy, AM; Karaskov, AM; Kornilov, IA; Lomivorotov, VN; Lomivorotov, VV1
Graudins, A; Kalam, Y1
Cromheecke, S; De Hert, SG; Lorsomradee, S; Van der Linden, PJ1

Reviews

5 review(s) available for simendan and Cardiac Diseases

ArticleYear
Levosimendan versus dobutamine for sepsis-induced cardiac dysfunction: a systematic review and meta-analysis.
    Scientific reports, 2021, 10-13, Volume: 11, Issue:1

    Topics: Disease-Free Survival; Dobutamine; Heart Diseases; Lactic Acid; Sepsis; Simendan; Stroke Volume; Survival Rate

2021
Effect of levosimendan on clinical outcomes in adult patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials.
    Interactive cardiovascular and thoracic surgery, 2018, 06-01, Volume: 26, Issue:6

    Topics: Adult; Cardiac Surgical Procedures; Global Health; Heart Diseases; Humans; Incidence; Length of Stay; Phosphodiesterase 3 Inhibitors; Postoperative Complications; Randomized Controlled Trials as Topic; Simendan; Survival Rate

2018
Perioperative Use of Levosimendan Improves Clinical Outcomes in Patients After Cardiac Surgery: A Systematic Review and Meta-Analysis.
    Journal of cardiovascular pharmacology, 2018, Volume: 72, Issue:1

    Topics: Acute Kidney Injury; Cardiac Surgical Procedures; Cardiovascular Agents; Drug Administration Schedule; Heart Diseases; Humans; Incidence; Intensive Care Units; Length of Stay; Perioperative Care; Renal Replacement Therapy; Respiration, Artificial; Risk Factors; Simendan; Stroke Volume; Time Factors; Treatment Outcome; Ventricular Function, Left

2018
Levosimendan meta-analyses: Is there a pattern in the effect on mortality?
    International journal of cardiology, 2016, Apr-15, Volume: 209

    Topics: Cardiotonic Agents; Cause of Death; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Heart Diseases; Humans; Hydrazones; Meta-Analysis as Topic; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Treatment Outcome

2016
Reducing mortality in cardiac surgery with levosimendan: a meta-analysis of randomized controlled trials.
    Journal of cardiothoracic and vascular anesthesia, 2010, Volume: 24, Issue:1

    Topics: Cardiopulmonary Bypass; Cardiotonic Agents; Coronary Artery Bypass, Off-Pump; Heart Diseases; Humans; Hydrazones; Postoperative Complications; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Treatment Outcome

2010

Trials

3 trial(s) available for simendan and Cardiac Diseases

ArticleYear
Levosimendan in septic shock in patients with biochemical evidence of cardiac dysfunction: a subgroup analysis of the LeoPARDS randomised trial.
    Intensive care medicine, 2019, Volume: 45, Issue:10

    Topics: Aged; Biomarkers; Chemokine CCL2; Double-Blind Method; Female; Heart Diseases; HSP90 Heat-Shock Proteins; Humans; Intensive Care Units; Interleukin-10; Interleukin-6; Interleukin-8; Male; Middle Aged; Natriuretic Peptide, Brain; Organ Dysfunction Scores; Peptide Fragments; Prognosis; Shock, Septic; Simendan; Troponin I; United Kingdom

2019
Levosimendan vs. intra-aortic balloon pump in high-risk cardiac surgery.
    Asian cardiovascular & thoracic annals, 2011, Volume: 19, Issue:2

    Topics: Aged; Biomarkers; Cardiopulmonary Bypass; Cardiotonic Agents; Chi-Square Distribution; Coronary Artery Bypass; Coronary Artery Disease; Female; Heart Diseases; Hemodynamics; Humans; Hydrazones; Intra-Aortic Balloon Pumping; Male; Middle Aged; Pyridazines; Risk Assessment; Risk Factors; Russia; Simendan; Stroke Volume; Treatment Outcome; Troponin I; Ventricular Function, Left

2011
The effects of levosimendan in cardiac surgery patients with poor left ventricular function.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:4

    Topics: Adrenergic beta-Agonists; Aged; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cardiotonic Agents; Dobutamine; Drug Administration Schedule; Drug Therapy, Combination; Elective Surgical Procedures; Female; Heart Diseases; Humans; Hydrazones; Intubation, Intratracheal; Length of Stay; Male; Middle Aged; Milrinone; Phosphodiesterase Inhibitors; Prospective Studies; Pyridazines; Simendan; Single-Blind Method; Stroke Volume; Time Factors; Treatment Outcome; Ventricular Function, Left

2007

Other Studies

5 other study(ies) available for simendan and Cardiac Diseases

ArticleYear
Comparison of dobutamine and levosimendan for treatment of sepsis-induced cardiac dysfunction: A protocol for systematic review and meta-analysis.
    Medicine, 2022, Mar-18, Volume: 101, Issue:11

    Topics: Dobutamine; Heart Diseases; Humans; Meta-Analysis as Topic; Sepsis; Simendan; Systematic Reviews as Topic

2022
Proarrhythmic changes in human cardiomyocytes during hypothermia by milrinone and isoprenaline, but not levosimendan: an experimental in vitro study.
    Scandinavian journal of trauma, resuscitation and emergency medicine, 2023, Oct-25, Volume: 31, Issue:1

    Topics: Cardiotonic Agents; Heart Diseases; Humans; Hydrazones; Hypothermia; Isoproterenol; Milrinone; Myocytes, Cardiac; Pyridazines; Simendan

2023
Use of Levosimendan in Cardiac Surgery: An Update After the LEVO-CTS, CHEETAH, and LICORN Trials in the Light of Clinical Practice.
    Journal of cardiovascular pharmacology, 2018, Volume: 71, Issue:1

    Topics: Cardiac Surgical Procedures; Cardiovascular Agents; Clinical Decision-Making; Congresses as Topic; Consensus; Evidence-Based Medicine; Heart Diseases; Humans; Patient Selection; Perioperative Care; Randomized Controlled Trials as Topic; Risk Factors; Simendan; Treatment Outcome

2018
Levosimendan prevents doxorubicin-induced cardiotoxicity in time- and dose-dependent manner: implications for inotropy.
    Cardiovascular research, 2020, 03-01, Volume: 116, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Calcium Signaling; Calcium-Binding Proteins; Cardiotoxicity; Cardiovascular Agents; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Doxorubicin; Female; Heart Diseases; Male; Mammary Neoplasms, Experimental; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Rats, Wistar; Simendan; Time Factors

2020
Levosimendan infusion improves cardiac output but not blood pressure in a rodent model of severe metoprolol toxicity.
    Human & experimental toxicology, 2012, Volume: 31, Issue:9

    Topics: Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Heart; Heart Diseases; Hydrazones; Male; Metoprolol; Pyridazines; Rats; Rats, Wistar; Simendan; Vasodilator Agents

2012