Page last updated: 2024-08-23

silybin and Parkinson Disease

silybin has been researched along with Parkinson Disease in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Feng, YB; Gong, JX; Huang, KX; Li, HB; Li, XK; Qu, J; Spencer, S; Tao, QF; Wang, F; Wu, XM; Wu, YH; Yang, LX; Zeng, S; Zhao, Y1
Chen, W; Fujisaki, H; Hattori, S; Hayashi, T; Ikejima, T; Liu, W; Liu, X; Mizuno, K; Wang, C1
Ebadi, SA; Eyvari Brooshghalan, S; Haddadi, R; Mohajjel Nayebi, A; Sabahi, M; Sadeghian, Z1
Chen, Y; Fujisaki, H; Hattori, S; Hayashi, T; Ikejima, T; Liu, P; Liu, W; Liu, X; Mizuno, K; Wang, C1
Ha, CM; Jang, JH; Jeong, JY; Jin, BK; Jung, UJ; Kim, DW; Kim, HJ; Kim, SR; Leem, E; Moon, GJ; Oh, YS; Shin, M; Shin, WH1
Choi, MS; Jeon, MT; Jung, UJ; Kim, SR1

Other Studies

6 other study(ies) available for silybin and Parkinson Disease

ArticleYear
Design, synthesis, and examination of neuron protective properties of alkenylated and amidated dehydro-silybin derivatives.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: Alkenes; Alzheimer Disease; Amides; Animals; Drug Design; Free Radical Scavengers; Humans; Iron Chelating Agents; Lipid Peroxidation; Liver; Male; Models, Molecular; Molecular Conformation; Neurons; Neuroprotective Agents; Parkinson Disease; PC12 Cells; Rats; Silymarin; Structure-Activity Relationship; Xanthine Oxidase

2009
Silibinin ameliorates depression/anxiety-like behaviors of Parkinson's disease mouse model and is associated with attenuated STING-IRF3-IFN-β pathway activation and neuroinflammation.
    Physiology & behavior, 2021, 11-01, Volume: 241

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anxiety; Depression; Disease Models, Animal; Humans; Interferon Regulatory Factor-3; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Parkinson Disease; Quality of Life; Silybin

2021
Silibinin chronic treatment in a rat model of Parkinson disease: A comprehensive in-vivo evaluation and in silico molecular modeling.
    European journal of pharmacology, 2023, Feb-15, Volume: 941

    Topics: Animals; bcl-2-Associated X Protein; Caspase 3; Interleukin-6; Molecular Docking Simulation; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; Proto-Oncogene Proteins c-bcl-2; Rats; Silybin; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2023
Silibinin attenuates motor dysfunction in a mouse model of Parkinson's disease by suppression of oxidative stress and neuroinflammation along with promotion of mitophagy.
    Physiology & behavior, 2021, 10-01, Volume: 239

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; Mitophagy; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Silybin; Substantia Nigra

2021
Effects of Silibinin Against Prothrombin Kringle-2-Induced Neurotoxicity in the Nigrostriatal Dopaminergic System In Vivo.
    Journal of medicinal food, 2019, Volume: 22, Issue:3

    Topics: Animals; Dopamine; Dopaminergic Neurons; Humans; Interleukin-1beta; Kringles; Male; Mice, Inbred C57BL; Microglia; Parkinson Disease; Prothrombin; Silybin; Tumor Necrosis Factor-alpha

2019
Silibinin attenuates MPP⁺-induced neurotoxicity in the substantia nigra in vivo.
    Journal of medicinal food, 2014, Volume: 17, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Disease Models, Animal; Dopaminergic Neurons; Dose-Response Relationship, Drug; Female; Inflammation; Interleukin-1beta; Microglia; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide Synthase Type II; Parkinson Disease; Rats; Rats, Sprague-Dawley; Silybin; Silymarin; Substantia Nigra; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase

2014