Page last updated: 2024-08-23

silybin and Neoplasms

silybin has been researched along with Neoplasms in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (10.53)29.6817
2010's14 (73.68)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L1
Amawi, H; Fetcenko, A; Hussein, N; Karthikeyan, C; Manivannan, E; Narayana Moorthy, NSH; Tiwari, AK; Trivedi, P1
Capasso, D; Di Fabio, G; Di Gaetano, S; Lembo, A; Pagano, R; Romanucci, V; Zarrelli, A1
Cai, H; Huo, M; Li, L; Wang, H; Yin, T; Zhang, P; Zhang, Y; Zhou, J1
Aggarwal, D; Barwal, TS; Iqubal, A; Jain, A; Kaur, G; Kumar, M; Mittal, S; Parashar, G; Parashar, NC; Sak, K; Savla, R; Sharma, AK; Tuli, HS; Upadhyay, SK; Varol, M1
Bosch-Barrera, J; Menendez, JA; Queralt, B1
Baradaran, B; Jahanafrooz, Z; Mokhtarzadeh, A; Motamed, N; Rinner, B1
Agarwal, R; Deep, G2
Siegel, AB; Stebbing, J1
Hagelgans, A; Menschikowski, M; Nacke, B; Siegert, G; Zamaraeva, M1
Wang, Q; Wang, Y; Zhang, D; Zhang, L1
Blagg, BS; Forsberg, LK; Hall, JA1
Bosch-Barrera, J; Menendez, JA1
Cheung, CW; Gibbons, N; Johnson, DW; Nicol, DL1
Gao, Y; He, D; Li, L; Zeng, J1
Barroso-Aranda, J; Contreras, F; McCarty, MF1
Agarwal, R; Raina, K1
Chamulitrat, W; Stremmel, W; Thongphasuk, P1

Reviews

11 review(s) available for silybin and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction

2015
Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance.
    Seminars in cancer biology, 2021, Volume: 73

    Topics: Animals; Antineoplastic Agents, Phytogenic; Humans; Neoplasms; Polyphenols; Silybin

2021
Targeting STAT3 with silibinin to improve cancer therapeutics.
    Cancer treatment reviews, 2017, Volume: 58

    Topics: Antineoplastic Agents; Antioxidants; Drug Resistance, Neoplasm; Humans; Liver Diseases; Neoplasms; Radiation Tolerance; Silybin; Silymarin; STAT3 Transcription Factor

2017
Silibinin to improve cancer therapeutic, as an apoptotic inducer, autophagy modulator, cell cycle inhibitor, and microRNAs regulator.
    Life sciences, 2018, Nov-15, Volume: 213

    Topics: Animals; Apoptosis; Autophagy; Cell Cycle; Cell Cycle Checkpoints; Cell Division; Cell Line, Tumor; Flavonolignans; Humans; MicroRNAs; Neoplasms; Signal Transduction; Silybin

2018
Targeting tumor microenvironment with silibinin: promise and potential for a translational cancer chemopreventive strategy.
    Current cancer drug targets, 2013, Volume: 13, Issue:5

    Topics: Animals; Antioxidants; Humans; Neoplasms; Silybin; Silymarin; Translational Research, Biomedical; Tumor Microenvironment

2013
Recent advances in the nanotechnology-based drug delivery of Silybin.
    Journal of biomedical nanotechnology, 2014, Volume: 10, Issue:4

    Topics: Antioxidants; Crystallization; Evidence-Based Medicine; Humans; Liver Diseases; Macromolecular Substances; Materials Testing; Molecular Conformation; Nanocapsules; Neoplasms; Silybin; Silymarin; Surface Properties; Suspensions; Treatment Outcome

2014
Silibinin and STAT3: A natural way of targeting transcription factors for cancer therapy.
    Cancer treatment reviews, 2015, Volume: 41, Issue:6

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Humans; Neoplasms; Phosphorylation; Silybin; Silymarin; STAT3 Transcription Factor

2015
Silibinin--a promising new treatment for cancer.
    Anti-cancer agents in medicinal chemistry, 2010, Volume: 10, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Neoplasms; Plant Extracts; Silybin; Silybum marianum; Silymarin; Treatment Outcome

2010
Targeting silibinin in the antiproliferative pathway.
    Expert opinion on investigational drugs, 2010, Volume: 19, Issue:2

    Topics: Androgen Receptor Antagonists; Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Proliferation; Clinical Trials as Topic; Drug Delivery Systems; Flavonoids; Humans; Models, Biological; Neoplasms; NF-kappa B; Phytotherapy; Receptor Protein-Tyrosine Kinases; Signal Transduction; Silybin; Silybum marianum; Silymarin; STAT Transcription Factors

2010
Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer.
    Cancer metastasis reviews, 2010, Volume: 29, Issue:3

    Topics: Animals; Antioxidants; Humans; Neoplasm Metastasis; Neoplasms; Signal Transduction; Silybin; Silybum marianum; Silymarin

2010
Combinatorial strategies for cancer eradication by silibinin and cytotoxic agents: efficacy and mechanisms.
    Acta pharmacologica Sinica, 2007, Volume: 28, Issue:9

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cytotoxins; Female; Humans; Lung Neoplasms; Male; Neoplasms; Prostatic Neoplasms; Silybin; Silymarin

2007

Other Studies

8 other study(ies) available for silybin and Neoplasms

ArticleYear
Design and discovery of silybin analogues as antiproliferative compounds using a ring disjunctive - Based, natural product lead optimization approach.
    European journal of medicinal chemistry, 2017, Jun-16, Volume: 133

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Membrane Potential, Mitochondrial; Molecular Docking Simulation; Neoplasms; Silybin; Silymarin; Tubulin; Tubulin Modulators

2017
Phosphodiester Silybin Dimers Powerful Radical Scavengers: A Antiproliferative Activity on Different Cancer Cell Lines.
    Molecules (Basel, Switzerland), 2022, Mar-05, Volume: 27, Issue:5

    Topics: Antioxidants; Cell Line; Neoplasms; Quercetin; Silybin; Silymarin

2022
Co-delivery of silybin and paclitaxel by dextran-based nanoparticles for effective anti-tumor treatment through chemotherapy sensitization and microenvironment modulation.
    Journal of controlled release : official journal of the Controlled Release Society, 2020, 05-10, Volume: 321

    Topics: Cell Line, Tumor; Dextrans; Humans; Nanoparticles; Neoplasms; Paclitaxel; Prospective Studies; Silybin; Tissue Distribution; Tumor Microenvironment; Xenograft Model Antitumor Assays

2020
Milk thistle: early seeds of potential.
    The Lancet. Oncology, 2013, Volume: 14, Issue:10

    Topics: Animals; Clinical Trials as Topic; Humans; Neoplasms; Phytotherapy; Silybin; Silybum marianum; Silymarin

2013
Silibinin down-regulates expression of secreted phospholipase A2 enzymes in cancer cells.
    Anticancer research, 2014, Volume: 34, Issue:4

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Neoplastic Stem Cells; Phospholipases A2, Secretory; RNA Isoforms; Signal Transduction; Silybin; Silymarin; Sp1 Transcription Factor; Tumor Stem Cell Assay

2014
Alternative approaches to Hsp90 modulation for the treatment of cancer.
    Future medicinal chemistry, 2014, Volume: 6, Issue:14

    Topics: Animals; Antineoplastic Agents; Catechin; Drug Discovery; HSP90 Heat-Shock Proteins; Humans; Models, Molecular; Neoplasms; Novobiocin; Silybin; Silymarin

2014
Practical strategies for suppressing hypoxia-inducible factor activity in cancer therapy.
    Medical hypotheses, 2010, Volume: 74, Issue:5

    Topics: Angiogenesis Inhibitors; Anthracyclines; Cardiac Glycosides; Cell Hypoxia; DNA Topoisomerases, Type I; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1; Intracellular Signaling Peptides and Proteins; Neoplasm Invasiveness; Neoplasms; NF-kappa B; Protein Serine-Threonine Kinases; Salicylic Acid; Silybin; Silymarin; TOR Serine-Threonine Kinases

2010
Potent direct or TNF-alpha-promoted anticancer effects of 2,3-dehydrosilybin: comparison study with silybin.
    Chemotherapy, 2008, Volume: 54, Issue:1

    Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Drug Therapy, Combination; Flow Cytometry; Humans; Necrosis; Neoplasms; Silybin; Silymarin; Time Factors; Tumor Necrosis Factor-alpha

2008