silybin has been researched along with Malignant Melanoma in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katayama, K; Ohta, T; Shoyama, Y; Uto, T | 1 |
| Abyaneh, HS; Lai, R; Lavasanifar, A; Loebenberg, R; Makhmalzadeh, BS; Molavi, O; Solimani, A; Vakili, MR; Zhang, HF | 1 |
| Ikejima, T; Jiang, YY; Onodera, S; Tashiro, S; Wang, HJ; Wang, J | 1 |
| Huang, H; Ikejima, T; Jiang, YY; Onodera, S; Tashiro, S; Wang, HJ; Wu, D; Yang, R | 2 |
5 other study(ies) available for silybin and Malignant Melanoma
| Article | Year |
|---|---|
Silibinin promotes melanogenesis through the PKA and p38 MAPK signaling pathways in melanoma cells.
Topics: Animals; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Humans; MAP Kinase Signaling System; Melanins; Melanoma; Mice; Monophenol Monooxygenase; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Silybin | 2022 |
Functionalized Caprolactone-Polyethylene Glycol Based Thermo-Responsive Hydrogels of Silibinin for the Treatment of Malignant Melanoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Caproates; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Hydrogels; Lactones; Melanoma; Melanoma, Cutaneous Malignant; Mice; Mice, Inbred C57BL; Molecular Structure; Polyethylene Glycols; Silybin; Skin Neoplasms; Temperature | 2018 |
The protective effect of silibinin against mitomycin C-induced intrinsic apoptosis in human melanoma A375-S2 cells.
Topics: Antibiotics, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytoprotection; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Formazans; Humans; L-Lactate Dehydrogenase; Melanoma; Membrane Potential, Mitochondrial; Mitochondria; Mitomycin; Molecular Structure; Silybin; Silymarin; Sirtuin 1; Tetrazolium Salts; Time Factors; Tumor Suppressor Protein p53 | 2009 |
Mechanism of autophagy induction and role of autophagy in antagonizing mitomycin C-induced cell apoptosis in silibinin treated human melanoma A375-S2 cells.
Topics: Adenine; Apoptosis; Autophagy; Cell Line, Tumor; Down-Regulation; Humans; Melanoma; Mitomycin; NF-kappa B; Pyrrolidines; Silybin; Silymarin; Thiocarbamates; Time Factors; Tumor Suppressor Protein p53 | 2011 |
Interruption of mitochondrial complex IV activity and cytochrome c expression activated O₂·⁻-mediated cell survival in silibinin-treated human melanoma A375-S2 cells via IGF-1R-PI3K-Akt and IGF-1R-PLC γ-PKC pathways.
Topics: Antioxidants; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochromes c; Electron Transport Complex IV; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Melanoma; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Protein Kinase C; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Signal Transduction; Silybin; Silymarin; Superoxide Dismutase; Superoxides | 2011 |