Page last updated: 2024-08-23

silybin and Innate Inflammatory Response

silybin has been researched along with Innate Inflammatory Response in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (5.41)29.6817
2010's22 (59.46)24.3611
2020's13 (35.14)2.80

Authors

AuthorsStudies
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J1
Dhaked, RK; Nagar, DP; Saxena, N1
Bagheri, N; Jafarzadeh, J; Karimi, A; Karimi, M; Musazadeh, V; Niazkar, HR; Sanaie, S; Vajdi, M1
Chen, X; Jiang, T; Li, Y; Lu, Y; Xu, J1
Chang, HY; Cheng, CD; Cheng, WC; Chih, SM; Dyke, TV; Huang, RY; Shieh, YS; Sung, CE; Weng, PW1
Cao, L; Ding, C; Hao, H; He, T; Shuai, Y; Wang, Y; Wu, J; Xie, Z; Xu, W; Zhang, C; Zhang, S1
Chen, Y; Forouzanfar, T; Han, Y; Huang, S; Jaspers, RT; Ji, Y; Li, X; Mao, Y; Shi, L; Sun, X; Wu, G; Zeng, J; Zhang, X; Zhou, R1
Che, L; Fang, Z; Feng, B; Hua, L; Jiang, X; Li, J; Lin, Y; Liu, Y; Ren, Z; Sun, M; Wang, J; Xu, S; Zhuo, Y1
Cho, YK; Jung, TY; Kim, HJ; Kim, JC; Kim, JS; Ko, JW; Lee, IC; Lee, SJ; Lim, JO; Nam, HH; Seo, YS; Shin, IS; Shin, NR1
Chen, J; Li, C; Li, DL; Liu, WF; Liu, X; Ma, YR; Wu, PP; Xie, LN; Xu, XT; Zhang, K; Zheng, X; Zhou, RP1
Ali Karami, M; Pooranian, M; Rezai, A; Sharif Makhmalzadeh, B1
Anagnostopoulos, K; Betsou, A; Georgakopoulou, AE; Konstandi, O; Kostomitsopoulos, N; Lambropoulou, M; Simopoulos, CE; Tsalikidis, C; Tsaroucha, AK; Valsami, G1
Chen, J; Chen, Z; Yang, XD; Yang, YY; Ye, L1
Ali, SA; Godugu, C; Saifi, MA; Talla, V1
Han, J; Liao, W; Pan, W; Shi, W; Song, J; Sun, Y1
Fernandes, V; Kalia, K; Sharma, D; Tiwari, V1
Kang, BS; Kwon, OS; Lee, DE; Lee, DS; Lee, HS; Lee, SJ; Nam, MJ; Park, JW1
Chen, Y; Liu, Y; Yu, Q1
Fernandes, CJDC; Peracoli, MTS; Veiga, MR; Zambuzzi, WF1
Ikejima, T; Jiang, S; Liu, W; Onodera, S; Tashiro, S; Wang, Q; Xie, X; Ye, Y; Zang, G; Zeng, H1
Bellanti, F; Giudetti, AM; Serviddio, G; Siculella, L; Stanca, E; Vendemiale, G1
Ali, F; Hamiza, OO; Hasan, SK; Khan, AQ; Khan, R; Lateef, A; Rehman, MU; Sultana, S; Tahir, M1
Barker, G; Lappas, M; Lim, R; Morwood, CJ1
Choi, MS; Jeon, MT; Jung, UJ; Kim, SR1
Khaleghi, N; Minaiyan, M; Varshosaz, J1
Dickerson, E; Kassie, F; Khammanivong, A; Qian, X; Song, JM; Teferi, F; Upadhyaya, P1
Kassie, F; Luo, X; Molla, K; O Sullivan, G; Qian, X; Song, JM; Teferi, F; Upadhyaya, P1
Bezbaruah, BK; Dwivedi, S; Gogoi, R; Gurjar, SS; Jangra, A; Kasbe, P; Kwatra, M; Lahkar, M; Mishra, M; Pandey, SN; Sarma, N; Sulakhiya, K; Venu, AK1
Du, Z; Li, Y; Liu, W; Zhang, K; Zheng, X1
Ahn, KS; Kim, JH; Kim, JS; Kwon, OK; Oh, SR; Park, JW; Shin, IS; Shin, NR1
Agarwal, C; Agarwal, R; Deep, G; Dhar, D; Guillermo-Lagae, R; Jain, AK; Orlicky, DJ; Rigby, CM; Roy, S1
Cui, L; Hattori, S; Hayashi, T; Ikejima, T; Lei, D; Onodera, S; Song, X; Tashiro, SI; Ushiki-Kaku, Y; Xia, M; Yao, G; Zhang, P; Zhou, B1
Bannwart, CF; Medeiros, LT; Nakaira-Takahagi, E; Peraçoli, JC; Peraçoli, MT; Romão, M; Silva, MG; Souza, CO; Weel, IC1
Agarwal, C; Agarwal, R; Inturi, S; Jain, AK; Tewari-Singh, N; White, CW1
Muthumani, M; Prabu, SM1
Agarwal, R; Chittezhath, M; Deep, G; Dwyer-Nield, LD; Kaur, M; Malkinson, AM; Singh, RP1
Agarwal, C; Agarwal, R; Dhanalakshmi, S; Gu, M; Singh, RP1

Reviews

1 review(s) available for silybin and Innate Inflammatory Response

ArticleYear
The favorable impacts of silibinin polyphenols as adjunctive therapy in reducing the complications of COVID-19: A review of research evidence and underlying mechanisms.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 154

    Topics: Antioxidants; COVID-19 Drug Treatment; Humans; Inflammation; Polyphenols; RNA; SARS-CoV-2; Silybin; Silymarin

2022

Other Studies

36 other study(ies) available for silybin and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature

2010
Silibinin ameliorates abrin induced hepatotoxicity by attenuating oxidative stress, inflammation and inhibiting Fas pathway.
    Environmental toxicology and pharmacology, 2022, Volume: 93

    Topics: Abrin; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Drug Interactions; fas Receptor; Inflammation; Mice; Oxidative Stress; Signal Transduction; Silybin

2022
Network Pharmacology Analysis and Experimental Validation to Explore the Anti-inflammatory Mechanism of Asiatic Acid on Alcoholic Steatohepatitis.
    Mediators of inflammation, 2022, Volume: 2022

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Cholesterol; Eosine Yellowish-(YS); Ethanol; Fatty Liver, Alcoholic; Hematoxylin; Inflammation; Interleukin-1beta; Interleukin-6; Lipids; Liver; Mice; Network Pharmacology; NF-kappa B; Silybin; Tumor Necrosis Factor-alpha

2022
Silibinin alleviates inflammation-induced bone loss by modulating biological interaction between human gingival fibroblasts and monocytes.
    Journal of periodontology, 2023, Volume: 94, Issue:7

    Topics: Cell Differentiation; Cytokines; Fibroblasts; Humans; Inflammation; Lipopolysaccharides; Monocytes; Osteoclasts; Periodontitis; RANK Ligand; Silybin

2023
Polyunsaturated fatty acids drive neutrophil extracellular trap formation in nonalcoholic steatohepatitis.
    European journal of pharmacology, 2023, Apr-15, Volume: 945

    Topics: Animals; Disease Models, Animal; Extracellular Traps; Fatty Acids, Unsaturated; Inflammation; Mice; Neutrophils; Non-alcoholic Fatty Liver Disease; Silybin

2023
Silibinin Attenuates Experimental Periodontitis by Downregulation of Inflammation and Oxidative Stress.
    Oxidative medicine and cellular longevity, 2023, Volume: 2023

    Topics: Animals; Anti-Inflammatory Agents; Down-Regulation; Humans; Inflammation; Lipopolysaccharides; NF-E2-Related Factor 2; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Periodontitis; Rats; Silybin

2023
Silibinin Alleviates Lipopolysaccharide Induced Inflammation in Porcine Mammary Epithelial Cells via mTOR/NF-κB Signaling Pathway.
    Molecular nutrition & food research, 2023, Volume: 67, Issue:14

    Topics: Animals; Epithelial Cells; Female; Inflammation; Lactation; Lipopolysaccharides; Mammals; NF-kappa B; NF-KappaB Inhibitor alpha; Signal Transduction; Silybin; Swine; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha

2023
Silibinin Attenuates Silica Dioxide Nanoparticles-Induced Inflammation by Suppressing TXNIP/MAPKs/AP-1 Signaling.
    Cells, 2020, 03-10, Volume: 9, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Humans; Inflammation; Mice; Mitogen-Activated Protein Kinases; Nanoparticles; Signal Transduction; Silicon Dioxide; Silybin

2020
Synergistic anti-inflammatory effects of silibinin and thymol combination on LPS-induced RAW264.7 cells by inhibition of NF-κB and MAPK activation.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2020, Volume: 78

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Drug Synergism; Inflammation; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; RAW 264.7 Cells; Reactive Oxygen Species; Silybin; Thymol; Tumor Necrosis Factor-alpha

2020
Preparation and optimization of silibinin-loaded chitosan-fucoidan hydrogel: an
    Pharmaceutical development and technology, 2021, Volume: 26, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Chitosan; Delayed-Action Preparations; Female; Hydrogels; Hydrogen Peroxide; Inflammation; Mice; Mice, Hairless; Polysaccharides; Silybin; Skin; Ultraviolet Rays

2021
The hepatoprotective effect of silibinin after hepatic ischemia/reperfusion in a rat model is confirmed by immunohistochemistry and qRT-PCR.
    The Journal of pharmacy and pharmacology, 2021, Aug-12, Volume: 73, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Chemokine CCL2; Freeze Drying; Inflammation; Ischemia; Liver; Liver Diseases; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Phytotherapy; Plant Extracts; Protective Agents; Random Allocation; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Silybin; Silymarin; Tissue Inhibitor of Metalloproteinase-2; Tumor Necrosis Factor-alpha

2021
Esculin protects against methionine choline-deficient diet-induced non-alcoholic steatohepatitis by regulating the Sirt1/NF-
    Pharmaceutical biology, 2021, Volume: 59, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Survival; Choline Deficiency; Cytokines; Esculin; Fatty Acids, Nonesterified; Fibrosis; Hep G2 Cells; Hepatocytes; Humans; Inflammation; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Models, Animal; NF-kappa B; Non-alcoholic Fatty Liver Disease; RNA, Small Interfering; Signal Transduction; Silybin; Sirtuin 1

2021
Silibinin alleviates silica-induced pulmonary fibrosis: Potential role in modulating inflammation and epithelial-mesenchymal transition.
    Phytotherapy research : PTR, 2021, Volume: 35, Issue:9

    Topics: Animals; Bleomycin; Epithelial-Mesenchymal Transition; Inflammation; Mice; Pulmonary Fibrosis; Silicon Dioxide; Silybin

2021
Aspergillus fumigatus-induced early inflammatory response in pulmonary microvascular endothelial cells: Role of p38 MAPK and inhibition by silibinin.
    International immunopharmacology, 2017, Volume: 49

    Topics: Antioxidants; Aspergillus fumigatus; Cells, Cultured; E-Selectin; Endothelium, Vascular; Gene Expression Regulation; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Invasive Pulmonary Aspergillosis; Lung; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; Silybin; Silymarin

2017
Neuroprotective effects of silibinin: an in silico and in vitro study.
    The International journal of neuroscience, 2018, Volume: 128, Issue:10

    Topics: Astrocytes; Cell Line, Tumor; Computer Simulation; Glial Fibrillary Acidic Protein; Humans; In Vitro Techniques; Inflammation; Lipid Peroxidation; Models, Molecular; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Silybin

2018
Silibinin Ameliorates
    International journal of molecular sciences, 2018, Jul-24, Volume: 19, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; beta-N-Acetylhexosaminidases; Choline Deficiency; Humans; Inflammation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; NF-kappa B; Non-alcoholic Fatty Liver Disease; Peroxiredoxins; Proteomics; RAW 264.7 Cells; Silybin; Silymarin

2018
Effect of silibinin on CFLAR-JNK pathway in oleic acid-treated HepG2 cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Down-Regulation; Glucose; Hep G2 Cells; Humans; Inflammation; Insulin Resistance; Lipid Metabolism; MAP Kinase Signaling System; Nitric Oxide; Oleic Acid; Oxidative Stress; Signal Transduction; Silybin; Triglycerides; Up-Regulation

2018
Modulatory effects of silibinin in cell behavior during osteogenic phenotype.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:8

    Topics: Animals; Bone Remodeling; Cell Adhesion; Cell Differentiation; Cell Line; Cell Proliferation; Extracellular Matrix; Humans; Inflammation; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Osteoblasts; Osteogenesis; Osteoporosis; Phenotype; Signal Transduction; Silybin

2019
p53-mediated autophagy adjustment is involved in the protection of silibinin against murine dermal inflammation and epidermal apoptosis induced by UVB irradiation.
    Journal of Asian natural products research, 2013, Volume: 15, Issue:2

    Topics: Animals; Apoptosis; Autophagy; Epidermis; Epithelial Cells; Inflammation; Male; Mice; Molecular Structure; Silybin; Silymarin; Skin Neoplasms; Tumor Suppressor Protein p53

2013
Down-regulation of LPCAT expression increases platelet-activating factor level in cirrhotic rat liver: potential antiinflammatory effect of silybin.
    Biochimica et biophysica acta, 2013, Volume: 1832, Issue:12

    Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Animals; Antioxidants; Blotting, Western; Chromatography, Thin Layer; Down-Regulation; Gene Expression Regulation; Inflammation; Liver Cirrhosis; Male; Microsomes, Liver; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Silybin; Silymarin

2013
Silibinin inhibits tumor promotional triggers and tumorigenesis against chemically induced two-stage skin carcinogenesis in Swiss albino mice: possible role of oxidative stress and inflammation.
    Nutrition and cancer, 2014, Volume: 66, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carcinogenesis; Catalase; Cell Transformation, Neoplastic; Chemoprevention; Cyclooxygenase 2; Down-Regulation; Female; Glucosephosphate Dehydrogenase; Inflammation; Interleukin-1beta; Interleukin-6; Lipid Peroxidation; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Silybin; Silymarin; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A

2014
Effect of silibinin in reducing inflammatory pathways in in vitro and in vivo models of infection-induced preterm birth.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Cyclooxygenase 2; Extraembryonic Membranes; Female; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Interleukin-8; Lipopolysaccharides; Mice; Myometrium; Pregnancy; Premature Birth; Silybin; Silymarin

2014
Silibinin attenuates MPP⁺-induced neurotoxicity in the substantia nigra in vivo.
    Journal of medicinal food, 2014, Volume: 17, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Disease Models, Animal; Dopaminergic Neurons; Dose-Response Relationship, Drug; Female; Inflammation; Interleukin-1beta; Microglia; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide Synthase Type II; Parkinson Disease; Rats; Rats, Sprague-Dawley; Silybin; Silymarin; Substantia Nigra; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase

2014
Eudragit nanoparticles loaded with silybin: a detailed study of preparation, freeze-drying condition and in vitro/in vivo evaluation.
    Journal of microencapsulation, 2015, Volume: 32, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Colon; Dexamethasone; Drug Carriers; Freeze Drying; Inflammation; Interleukin-6; Male; Nanoparticles; Peroxidase; Polymethacrylic Acids; Rats, Wistar; Silybin; Silybum marianum; Silymarin; Tumor Necrosis Factor-alpha

2015
RNA-sequencing studies identify genes differentially regulated during inflammation-driven lung tumorigenesis and targeted by chemopreventive agents.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2015, Volume: 64, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Female; Gene Expression Regulation, Neoplastic; Indoles; Inflammation; Lipopolysaccharides; Lung; Lung Neoplasms; Mice; Mice, Inbred A; RNA; Sequence Analysis, RNA; Silybin; Silymarin

2015
Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators.
    Carcinogenesis, 2015, Volume: 36, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Cyclin D1; Cyclin-Dependent Kinases; Cyclooxygenase 2; Drug Combinations; Female; Humans; I-kappa B Proteins; Indoles; Inflammation; Interleukin-6; Lipopolysaccharides; Lung; Lung Neoplasms; Mice; Mice, Inbred A; NF-KappaB Inhibitor alpha; Nitrosamines; Proto-Oncogene Proteins c-akt; Random Allocation; Retinoblastoma Protein; Silybin; Silymarin; Smoke; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha

2015
Hesperidin and Silibinin Ameliorate Aluminum-Induced Neurotoxicity: Modulation of Antioxidants and Inflammatory Cytokines Level in Mice Hippocampus.
    Biological trace element research, 2015, Volume: 168, Issue:2

    Topics: Aluminum; Animals; Antioxidants; Behavior, Animal; Brain-Derived Neurotrophic Factor; Catalase; Cognition Disorders; Cytokines; Glutathione; Hesperidin; Hippocampus; Inflammation; Interleukin-1beta; Lipid Peroxidation; Male; Maze Learning; Mice; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Nitrogen; Oxidative Stress; Silybin; Silymarin; Tumor Necrosis Factor-alpha

2015
Potent inhibitory effect of silibinin from milk thistle on skin inflammation stimuli by 12-O-tetradecanoylphorbol-13-acetate.
    Food & function, 2015, Volume: 6, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase 2; Dermatitis; Dose-Response Relationship, Drug; Female; Inflammation; Interleukin-1beta; Interleukin-6; Mice; Mice, Inbred BALB C; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Silybin; Silybum marianum; Silymarin; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2015
Silibinin Inhibits Neutrophilic Inflammation and Mucus Secretion Induced by Cigarette Smoke via Suppression of ERK-SP1 Pathway.
    Phytotherapy research : PTR, 2016, Volume: 30, Issue:12

    Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Inflammation; Male; Mice; Mice, Inbred C57BL; Mucus; Neutrophils; Phosphorylation; Plants, Medicinal; Reactive Oxygen Species; Signal Transduction; Silybin; Silymarin

2016
Role of p53 in silibinin-mediated inhibition of ultraviolet B radiation-induced DNA damage, inflammation and skin carcinogenesis.
    Carcinogenesis, 2017, Volume: 38, Issue:1

    Topics: Animals; Antioxidants; Cell Transformation, Neoplastic; DNA Damage; Female; Inflammation; Male; Mice; Mice, Hairless; Mice, Inbred C57BL; Mice, Knockout; Silybin; Silymarin; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays

2017
Silibinin ameliorates Aβ
    Neurochemical research, 2017, Volume: 42, Issue:4

    Topics: Amyloid beta-Peptides; Animals; Antioxidants; Autophagy; Dose-Response Relationship, Drug; Inflammation; Male; Memory Disorders; Oxidative Stress; Peptide Fragments; Random Allocation; Rats; Rats, Sprague-Dawley; Silybin; Silymarin

2017
Hepatoprotective and anti-inflammatory effects of silibinin on experimental preeclampsia induced by L-NAME in rats.
    Life sciences, 2012, Sep-04, Volume: 91, Issue:5-6

    Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunologic Factors; Inflammation; Liver; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Protective Agents; Rats; Rats, Wistar; Silybin; Silymarin

2012
Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Antidotes; Apoptosis; Cells, Cultured; Chemical Warfare Agents; Cyclooxygenase 2; Deoxyguanosine; DNA Damage; Female; Gene Expression Regulation; Humans; Inflammation; Matrix Metalloproteinase 9; Mice; Mice, Hairless; Mustard Gas; Nitric Oxide Synthase Type II; Oxidative Stress; Signal Transduction; Silybin; Silymarin; Skin

2012
Silibinin ameliorates arsenic induced nephrotoxicity by abrogation of oxidative stress, inflammation and apoptosis in rats.
    Molecular biology reports, 2012, Volume: 39, Issue:12

    Topics: Adenosine Triphosphatases; Animals; Antioxidants; Apoptosis; Arsenic; Biomarkers; Caspase 3; Drinking Behavior; Feeding Behavior; Inflammation; Kidney; Kidney Diseases; Membranes; NADPH Oxidases; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Organ Size; Oxidative Stress; Protein Binding; Rats; Real-Time Polymerase Chain Reaction; Silybin; Silymarin; Tumor Necrosis Factor-alpha; Weight Gain

2012
Effect of silibinin on the growth and progression of primary lung tumors in mice.
    Journal of the National Cancer Institute, 2006, Jun-21, Volume: 98, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Blotting, Western; Carcinogens; Cell Proliferation; Cyclin D1; Cyclooxygenase 2; Disease Models, Animal; Fibroblast Growth Factor 2; Immunohistochemistry; Inflammation; Lung Neoplasms; Mice; Microcirculation; Neovascularization, Pathologic; Nitric Oxide Synthase Type II; Platelet Endothelial Cell Adhesion Molecule-1; Proliferating Cell Nuclear Antigen; Silybin; Silymarin; Urethane; Vascular Endothelial Growth Factor A

2006
Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice.
    Cancer research, 2007, Apr-01, Volume: 67, Issue:7

    Topics: Animals; Antioxidants; Cell Growth Processes; Cell Nucleus; Cell Transformation, Neoplastic; Cyclooxygenase 2; Female; Inflammation; Mice; Mice, Hairless; Neovascularization, Pathologic; NF-kappa B; Nitric Oxide Synthase Type II; Phosphorylation; Silybin; Silymarin; Skin; Skin Neoplasms; STAT3 Transcription Factor; Ultraviolet Rays

2007