Page last updated: 2024-08-23

silybin and Hepatitis C, Chronic

silybin has been researched along with Hepatitis C, Chronic in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (27.78)29.6817
2010's13 (72.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brambilla, N; Bringiotti, RS; Castellaneta, A; Castellaneta, NM; D'Amato, M; Di Leo, A; Giacovelli, G; Rendina, M; Rizzi, SF; Rovati, L; Zappimbulso, M1
Bander, D; Jurczyk, K; Karpińska, E; Lachtara, M; Laurans, Ł; Socha, Ł; Wawrzynowicz-Syczewska, M1
Galle, PR; Knapstein, J; Wörns, MA; Zimmermann, T1
Anagnostopoulos, A; Aouri, M; Böni, J; Braun, DL; Decosterd, L; Durisch, N; Eberhard, N; Fehr, J; Ledergerber, B; Metzner, KJ; Müllhaupt, B; Rauch, A; Weber, R1
Bertino, G; Caraci, F; Chisari, G; Drago, F; Greco, C; Malaguarnera, G; Malaguarnera, M; Motta, M; Nunnari, G; Vacante, M; Vecchio, M1
Beinhardt, S; Ferenci, P; Hofer, H; Holzmann, H; Kerschner, H; Rutter, K; Scherzer, TM; Schöniger-Hekele, M; Steindl-Munda, P1
Fehér, J; Lengyel, G1
Glushenkov, DV; Maevskaia, MV; Tel'nykh, IuV1
Berg, T; Biermer, M1
Berg, T; Biermer, M; Eurich, D; Neuhaus, P; Neumann, UP1
Beinhardt, S; Ferenci, P; Payer, BA; Peck-Radosavljevic, M; Reiberger, T; Rutter, K; Staettermayer, AF1
Beinhardt, S; Ferenci, P; Rasoul-Rockenschaub, S; Scherzer, TM1
Hokari, A1
Beinhardt, S; Ferenci, P; Hofer, H; Kerschner, H; Popow-Kraupp, T; Rutter, K; Scherzer, TM; Stättermayer, AF; Steindl-Munda, P1
Bourlière, M; Le Folgoc, G; Lecomte, L; Wartelle-Bladou, C1
Berg, T; Biermer, M; Brodzinski, A; Fülöp, B; Heyne, R; Keller, K; Sarrazin, C; Schlosser, B; van Bömmel, F1
Bartenschlager, R; Binder, M; Eisenbach, C; Esser-Nobis, K; Ganten, TM; Gouttenoire, J; Harak, C; Klein, R; Lohmann, V; Moradpour, D; Penin, F; Polyak, SJ; Romero-Brey, I; Schemmer, P; Schnitzler, P; Stremmel, W1
D'Auria, M; de Sio, I; Di Leva, A; Federico, A; Loguercio, C; Niosi, M; Trappoliere, M; Tuccillo, C1

Reviews

3 review(s) available for silybin and Hepatitis C, Chronic

ArticleYear
[Silymarin in the treatment of chronic liver diseases: past and future].
    Orvosi hetilap, 2008, Dec-21, Volume: 149, Issue:51

    Topics: Antioxidants; Carcinoma, Hepatocellular; Chronic Disease; Colorectal Neoplasms; Fatty Liver; Fatty Liver, Alcoholic; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Diseases; Liver Diseases, Alcoholic; Liver Neoplasms; Oxidative Stress; Silybin; Silymarin; Survival Analysis; Treatment Outcome

2008
[Improved virologic response in chronic hepatitis C treated with peginterferon, ribavirin and add-on drug].
    Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69 Suppl 4

    Topics: Antiviral Agents; Cyclosporine; Diterpenes; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fatty Alcohols; Female; Fluvastatin; Hepatitis C, Chronic; Humans; Indoles; Interferon-alpha; Male; Metformin; Nitro Compounds; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Silybin; Silymarin; Thiazoles

2011
Hepatitis C therapy in non-genotype 1 patients: the near future.
    Journal of viral hepatitis, 2012, Volume: 19, Issue:8

    Topics: Antioxidants; Antiviral Agents; Clinical Trials as Topic; Cyclophilins; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Protease Inhibitors; Ribavirin; Silybin; Silymarin

2012

Trials

6 trial(s) available for silybin and Hepatitis C, Chronic

ArticleYear
Antiviral activity and safety profile of silibinin in HCV patients with advanced fibrosis after liver transplantation: a randomized clinical trial.
    Transplant international : official journal of the European Society for Organ Transplantation, 2014, Volume: 27, Issue:7

    Topics: Antiviral Agents; Double-Blind Method; Hepatitis C, Chronic; Humans; Interferon-alpha; Liver Transplantation; Polyethylene Glycols; Prospective Studies; Ribavirin; Silybin; Silymarin

2014
A Lead-In with Silibinin Prior to Triple-Therapy Translates into Favorable Treatment Outcomes in Difficult-To-Treat HIV/Hepatitis C Coinfected Patients.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Adult; Antiretroviral Therapy, Highly Active; Antiviral Agents; Coinfection; Drug Administration Schedule; Female; Hepacivirus; Hepatitis C, Chronic; HIV; HIV Infections; Humans; Injections, Intravenous; Interferon-alpha; Liver Cirrhosis; Male; Middle Aged; Oligopeptides; Patient Safety; Polyethylene Glycols; Prospective Studies; Protease Inhibitors; Recombinant Proteins; Ribavirin; RNA, Viral; Silybin; Silymarin; Treatment Outcome; Viral Load

2015
Silybin supplementation during HCV therapy with pegylated interferon-α plus ribavirin reduces depression and anxiety and increases work ability.
    BMC psychiatry, 2016, Nov-15, Volume: 16, Issue:1

    Topics: Adult; Antioxidants; Antiviral Agents; Anxiety; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Psychiatric Status Rating Scales; Ribavirin; Silybin; Silymarin; Treatment Outcome; Work Performance

2016
Silibinin is a potent antiviral agent in patients with chronic hepatitis C not responding to pegylated interferon/ribavirin therapy.
    Gastroenterology, 2008, Volume: 135, Issue:5

    Topics: Antioxidants; Antiviral Agents; Dose-Response Relationship, Drug; Drug Carriers; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Free Radical Scavengers; Hepacivirus; Hepatitis C, Chronic; Humans; Infusions, Intravenous; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Polymerase Chain Reaction; Recombinant Proteins; Ribavirin; RNA, Viral; Silybin; Silybum marianum; Silymarin; Time Factors; Treatment Outcome; Viral Load

2008
[The use of hepatoprotector LiverPro in combined therapy of chronic viral hepatitis C].
    Klinicheskaia meditsina, 2008, Volume: 86, Issue:11

    Topics: Adult; Antiviral Agents; Drug Combinations; Drug Therapy; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interferons; Liver; Male; Phosphatidylcholines; Silybin; Silymarin; Young Adult

2008
[Effects of a new pharmacological complex (silybin + vitamin-E + phospholipids) on some markers of the metabolic syndrome and of liver fibrosis in patients with hepatic steatosis. Preliminary study].
    Minerva gastroenterologica e dietologica, 2005, Volume: 51, Issue:2

    Topics: Adult; Aged; Biomarkers; Drug Combinations; Fatty Liver; Female; Hepatitis C, Chronic; Humans; Insulin Resistance; Liver Cirrhosis; Male; Metabolic Syndrome; Middle Aged; Phospholipids; Pilot Projects; Silybin; Silymarin; Vitamin E

2005

Other Studies

9 other study(ies) available for silybin and Hepatitis C, Chronic

ArticleYear
Rescue therapy with intravenous silibinin in liver transplant recipients with recurrent HCV hepatitis - two case reports.
    Annals of transplantation, 2014, Apr-08, Volume: 19

    Topics: Administration, Intravenous; Antiviral Agents; Carcinoma, Hepatocellular; Hepatitis C, Chronic; Humans; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Recurrence; Salvage Therapy; Silybin; Silymarin

2014
Combination therapy with silibinin, pegylated interferon and ribavirin in a patient with hepatitis C virus genotype 3 reinfection after liver transplantation: a case report.
    Journal of medical case reports, 2014, Jul-21, Volume: 8

    Topics: Antiviral Agents; Drug Therapy, Combination; Genotype; Hepatitis C, Chronic; Humans; Immunosuppressive Agents; Interferon-alpha; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Recurrence; Ribavirin; Silybin; Silymarin

2014
Rapid suppression of hepatitis C viremia induced by intravenous silibinin plus ribavirin.
    Gastroenterology, 2009, Volume: 137, Issue:1

    Topics: Aged; Antiviral Agents; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Infusions, Intravenous; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Silybin; Silymarin; Treatment Outcome; Viral Load

2009
Successful prevention of hepatitis C virus (HCV) liver graft reinfection by silibinin mono-therapy.
    Journal of hepatology, 2010, Volume: 52, Issue:6

    Topics: Antioxidants; Hepatitis C, Chronic; Humans; Liver Transplantation; Male; Middle Aged; Postoperative Complications; Secondary Prevention; Silybin; Silymarin

2010
Successful HCV eradication and inhibition of HIV replication by intravenous silibinin in an HIV-HCV coinfected patient.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2010, Volume: 49, Issue:2

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Female; Hepacivirus; Hepatitis C, Chronic; HIV; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Silybin; Silymarin; Treatment Outcome; Viral Load

2010
Silibinin monotherapy prevents graft infection after orthotopic liver transplantation in a patient with chronic hepatitis C.
    Journal of hepatology, 2011, Volume: 54, Issue:3

    Topics: Antiviral Agents; End Stage Liver Disease; Hepatitis C, Chronic; Humans; Liver Transplantation; Male; Middle Aged; Secondary Prevention; Silybin; Silymarin; Viral Load

2011
Intravenous silibinin as 'rescue treatment' for on-treatment non-responders to pegylated interferon/ribavirin combination therapy.
    Antiviral therapy, 2011, Volume: 16, Issue:8

    Topics: Adult; Antioxidants; Antiviral Agents; Austria; Cohort Studies; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Injections, Intravenous; Interferon-alpha; Interferons; Interleukins; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Recurrence; Ribavirin; RNA, Viral; Silybin; Silymarin; Treatment Outcome; Viral Load; Virus Replication

2011
High-dose silibinin rescue treatment for HCV-infected patients showing suboptimal virologic response to standard combination therapy.
    Journal of viral hepatitis, 2012, Volume: 19, Issue:8

    Topics: Adult; Aged; Antioxidants; Antiviral Agents; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Infusions, Intravenous; Interferon-alpha; Male; Middle Aged; Ribavirin; Silybin; Silymarin; Treatment Outcome; Viremia

2012
Analysis of hepatitis C virus resistance to silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:3

    Topics: Antioxidants; Antiviral Agents; Cells, Cultured; Drug Resistance, Viral; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; In Vitro Techniques; Male; Phenotype; Silybin; Silymarin; Viral Nonstructural Proteins; Virus Replication

2013