silybin has been researched along with Colorectal Cancer in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 10 (66.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bahreini, F; Najafi, R; Saidijam, M; Sameri, S | 1 |
| Alfonso-Moreno, V; López-Serrano, A; Moreno-Osset, E | 1 |
| Agarwal, C; Agarwal, R; Raina, K; Serkova, NJ; Wadhwa, R | 1 |
| Huso, DL; Karim, BO; Liu, G; Rhee, KJ; Zheng, D | 1 |
| Agarwal, R; Raina, K | 1 |
| Chen, LJ; Cheng, JT; Chuang, TW; Chung, KM; Lin, KC; Niu, HS; Tsai, CC | 1 |
| Fehér, J; Lengyel, G | 1 |
| Agarwal, C; Agarwal, R; Deep, G; Katiyar, S; Kaur, M; Tyagi, A; Velmurugan, B | 1 |
| Agarwal, R; Kaur, M; Rajamanickam, S; Singh, RP; Velmurugan, B | 1 |
| Agarwal, C; Agarwal, R; Kaur, M; Singh, RP; Tyagi, A; Velmurugan, B | 1 |
| Agarwal, C; Agarwal, R; Raina, K | 1 |
| Chang, CC; Chen, WM; Chiang, CC; Hung, SC; Wang, JY | 1 |
| Gardner, TR; Grieco, M; Herath, SA; Jang, JH; Kirchoff, D; Naffouje, S; Njoh, L; Shantha Kumara, HM; Whelan, RL; Yan, X | 1 |
| Berry, DP; Boocock, D; Dennison, AR; Euden, S; Farmer, PB; Garcea, G; Gescher, AJ; Hemingway, D; Hoh, C; Marczylo, T; Miller, A; Singh, R; Steward, WP; West, K | 1 |
| Agarwal, R; Gu, M; Singh, RP | 1 |
1 review(s) available for silybin and Colorectal Cancer
| Article | Year |
|---|---|
[Silymarin in the treatment of chronic liver diseases: past and future].
Topics: Antioxidants; Carcinoma, Hepatocellular; Chronic Disease; Colorectal Neoplasms; Fatty Liver; Fatty Liver, Alcoholic; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Diseases; Liver Diseases, Alcoholic; Liver Neoplasms; Oxidative Stress; Silybin; Silymarin; Survival Analysis; Treatment Outcome | 2008 |
14 other study(ies) available for silybin and Colorectal Cancer
| Article | Year |
|---|---|
Cancer Chemopreventive Activities of Silibinin on Colorectal Cancer through Regulation of E-Cadherin/β-Catenin Pathway.
Topics: beta Catenin; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Doublecortin-Like Kinases; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Protein Serine-Threonine Kinases; Silybin; Wnt Signaling Pathway | 2021 |
Chemoprevention of polyp recurrence with curcumin followed by silibinin in a case of multiple colorectal adenomas.
Topics: Antineoplastic Agents; Chemoprevention; Colorectal Neoplasms; Curcumin; Drug Therapy, Combination; Humans; Intestinal Polyps; Male; Middle Aged; Recurrence; Silybin; Silymarin | 2017 |
Energy deprivation by silibinin in colorectal cancer cells: a double-edged sword targeting both apoptotic and autophagic machineries.
Topics: Adenine; AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Cell Line, Tumor; Cell Shape; Cell Survival; Colorectal Neoplasms; Endoplasmic Reticulum Stress; Energy Metabolism; Enzyme Activation; Epidermal Growth Factor; Humans; Macrolides; Metabolomics; Mice; Mitogens; Models, Biological; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Silybin; Silymarin; Somatomedins; TOR Serine-Threonine Kinases; Vacuoles | 2013 |
Chemoprevention utility of silibinin and Cdk4 pathway inhibition in Apc(-/+) mice.
Topics: Adenoma; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemoprevention; Colorectal Neoplasms; Cyclin D1; Cyclin-Dependent Kinase 4; Disease Models, Animal; Female; Genes, APC; Humans; Ki-67 Antigen; Mice; Mice, Knockout; Retinoblastoma Protein; Signal Transduction; Silybin; Silymarin | 2013 |
Promise and potential of silibinin in colorectal cancer management: what patterns can be seen?
Topics: Colorectal Neoplasms; Humans; Metabolomics; Silybin; Silymarin | 2013 |
Increase in apoptosis by combination of metformin with silibinin in human colorectal cancer cells.
Topics: AMP-Activated Protein Kinases; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Synergism; Humans; Metformin; Phosphorylation; PTEN Phosphohydrolase; Signal Transduction; Silybin; Silymarin; TOR Serine-Threonine Kinases | 2015 |
Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Cycle Proteins; Cell Death; Colorectal Neoplasms; Humans; Male; Mice; Mice, Nude; Silybin; Silymarin; Xenograft Model Antitumor Assays | 2009 |
Chemoprevention of intestinal tumorigenesis in APCmin/+ mice by silibinin.
Topics: Adenomatous Polyposis Coli; Animals; Antioxidants; Apoptosis; beta Catenin; Cell Growth Processes; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Intestinal Polyps; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Silybin; Silymarin; Transcriptional Activation | 2010 |
Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of beta-catenin-dependent signaling.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; beta Catenin; Blotting, Western; Cell Proliferation; Colorectal Neoplasms; Cyclin-Dependent Kinase 8; Down-Regulation; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Genes, APC; HCT116 Cells; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Nude; Microscopy, Confocal; Signal Transduction; Silybin; Silymarin; Wnt Proteins; Xenograft Model Antitumor Assays | 2010 |
Effect of silibinin in human colorectal cancer cells: targeting the activation of NF-κB signaling.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Colorectal Neoplasms; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Male; Mice; Mice, Nude; NF-kappa B; Protein Transport; Signal Transduction; Silybin; Silymarin; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays | 2013 |
Silibinin suppresses the maintenance of colorectal cancer stem-like cells by inhibiting PP2A/AKT/mTOR pathways.
Topics: AC133 Antigen; Animals; Antigens, CD; Antineoplastic Agents; Apoptosis; Colorectal Neoplasms; Glycoproteins; HT29 Cells; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Neoplastic Stem Cells; Peptides; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Signal Transduction; Silybin; Silymarin; Spheroids, Cellular; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2012 |
Perioperative polyphenon E- and siliphos-inhibited colorectal tumor growth and metastases without impairment of gastric or abdominal wound healing in mouse models.
Topics: Abdomen; Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Collagen; Colorectal Neoplasms; Drug Combinations; Female; Laparotomy; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasm Transplantation; Perioperative Period; Pneumoperitoneum, Artificial; Pressure; Random Allocation; Silybin; Silymarin; Stomach; Surgical Wound Dehiscence; Wound Healing | 2012 |
Pilot study of oral silibinin, a putative chemopreventive agent, in colorectal cancer patients: silibinin levels in plasma, colorectum, and liver and their pharmacodynamic consequences.
Topics: Administration, Oral; Aged; Anticarcinogenic Agents; Colorectal Neoplasms; Female; Humans; Insulin-Like Growth Factor Binding Protein 3; Male; Metabolic Clearance Rate; Middle Aged; Phytotherapy; Silybin; Silybum marianum; Silymarin | 2006 |
Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis.
Topics: Animals; Antioxidants; Apoptosis; Cell Growth Processes; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 2; Enzyme Activation; HT29 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neovascularization, Pathologic; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oncogene Protein v-akt; Silybin; Silymarin; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2008 |