silybin has been researched along with Carcinoma, Squamous Cell in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, WC; Chen, YW; Cheng, JC; Hsieh, CC; Li, YH; Lin, CK; Lin, CS; Lin, GJ; Sytwu, HK; Tsao, CH; Wang, YL; Yang, CY | 1 |
| An, L; Bai, B; Chen, J; Li, X; Yang, X | 1 |
| Hayashi, T; He, H; Ikejima, T; Li, L; Liu, W; Onodera, S; Otkur, W; Tashiro, S; Wang, Q; Ye, Y; Zhang, Y | 1 |
| Chang, YC; Hu, FW; Jan, CI; Lai, YC; Peng, CY; Yu, CC | 1 |
| Chan, KT; Chan, KW; Cheung, AL; Guan, XY; Law, S; Lee, NP; Li, B; Li, J; Qin, YR; Tsao, SW; Xu, WW | 1 |
| Bang, CI; Joo, YH; Kim, MS; Paik, SY; Sun, DI | 1 |
| Fan, S; Ikejima, T; Li, L; Onodera, S; Qi, M; Tashiro, S; Yao, G; Yu, Y | 1 |
| Fan, SM; Ikejima, T; Onodera, S; Tashiro, S; Yu, Y; Yuan, SJ | 1 |
| Chen, PN; Chiang, CL; Chiou, HL; Chu, SC; Hsieh, YS; Yang, SF | 1 |
9 other study(ies) available for silybin and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
Downregulation of Jumonji-C domain-containing protein 5 inhibits proliferation by silibinin in the oral cancer PDTX model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Histone Demethylases; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Mouth Neoplasms; Prognosis; Repressor Proteins; Silybin; Survival Rate; Trans-Activators; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
Silibinin induced the apoptosis of Hep-2 cells via oxidative stress and down-regulating survivin expression.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Carcinoma, Squamous Cell; Caspase 3; Cell Line, Tumor; Down-Regulation; Gene Expression; Humans; Inhibitor of Apoptosis Proteins; Laryngeal Neoplasms; Membrane Potential, Mitochondrial; Neoplasm Proteins; Oxidative Stress; Oxides; Reactive Oxygen Species; RNA, Messenger; Silybin; Silymarin; Survivin | 2013 |
Autophagy induced by silibinin protects human epidermoid carcinoma A431 cells from UVB-induced apoptosis.
Topics: Androstadienes; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; Beclin-1; Carcinoma, Squamous Cell; Humans; Membrane Proteins; Microtubule-Associated Proteins; Receptor, IGF Type 1; RNA, Small Interfering; Silybin; Silymarin; Sirolimus; Tumor Cells, Cultured; Ultraviolet Rays; Wortmannin | 2013 |
Activation of microRNA-494-targeting Bmi1 and ADAM10 by silibinin ablates cancer stemness and predicts favourable prognostic value in head and neck squamous cell carcinomas.
Topics: AC133 Antigen; ADAM Proteins; ADAM10 Protein; Aldehyde Dehydrogenase 1 Family; Amyloid Precursor Protein Secretases; Animals; Antigens, CD; Carcinoma, Squamous Cell; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Glycoproteins; Head and Neck Neoplasms; Humans; Hyaluronan Receptors; Incidence; Isoenzymes; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Peptides; Phenotype; Polycomb Repressive Complex 1; Prognosis; Retinal Dehydrogenase; Silybin; Silymarin | 2015 |
Role of AMPK signaling in mediating the anticancer effects of silibinin in esophageal squamous cell carcinoma.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasm Invasiveness; Signal Transduction; Silybin; Silymarin; Xenograft Model Antitumor Assays | 2016 |
Cell growth inhibition and down-regulation of survivin by silibinin in a laryngeal squamous cell carcinoma cell line.
Topics: Antioxidants; Apoptosis; Biomarkers, Tumor; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Laryngeal Neoplasms; Microtubule-Associated Proteins; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Silybin; Silybum marianum; Silymarin; Survivin | 2008 |
P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK.
Topics: Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; Benzothiazoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Genes, p53; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Reactive Oxygen Species; Silybin; Silymarin; Toluene; Tumor Suppressor Protein p53; Vulvar Neoplasms | 2012 |
Nitric oxide (•NO) generation but not ROS plays a major role in silibinin-induced autophagic and apoptotic death in human epidermoid carcinoma A431 cells.
Topics: Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Line, Tumor; Free Radicals; Humans; Lipid Peroxidation; Membrane Potential, Mitochondrial; Membrane Proteins; Nitric Oxide; Reactive Oxygen Species; Signal Transduction; Silybin; Silymarin | 2012 |
Silibinin inhibits invasion of oral cancer cells by suppressing the MAPK pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Carcinoma, Squamous Cell; Cell Line, Tumor; Humans; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; Protease Inhibitors; Silybin; Silymarin; Tongue Neoplasms; Urokinase-Type Plasminogen Activator | 2006 |