silybin has been researched along with Cancer of Skin in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 9 (50.00) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Agarwal, C; Agarwal, R; Deep, G; Kant, R; Maurya, A; Orlicky, DJ; Paudel, S; Raina, B; Raina, K; Rigby, CM; Tiku, VR; You, Z | 1 |
| Abyaneh, HS; Lai, R; Lavasanifar, A; Loebenberg, R; Makhmalzadeh, BS; Molavi, O; Solimani, A; Vakili, MR; Zhang, HF | 1 |
| Agarwal, C; Agarwal, R; Deep, G; Jain, A; Orlicky, DJ; Rigby, C | 1 |
| Ikejima, T; Jiang, S; Liu, W; Onodera, S; Tashiro, S; Wang, Q; Xie, X; Ye, Y; Zang, G; Zeng, H | 1 |
| Agarwal, C; Agarwal, R; Biedermann, D; Deep, G; Kren, V; Tilley, C; Valentová, K; Wempe, MF | 1 |
| Agarwal, R; Deep, G; Tilley, C | 1 |
| Garg, ML; Koul, A; Mohanty, BP; Sati, J | 1 |
| Agarwal, C; Agarwal, R; Deep, G; Dhar, D; Guillermo-Lagae, R; Jain, AK; Orlicky, DJ; Rigby, CM; Roy, S | 1 |
| Agarwal, C; Agarwal, R; Deep, G; Dheeraj, A; O'Bryant, CL; Rigby, CM; Singh, RP | 1 |
| Adriana, M; Clichici, S; Daicoviciu, D; Filip, A; Olteanu, D; Perde-Schrepler, M; Postescu, ID | 1 |
| Agarwal, C; Agarwal, R; Deep, G; Roy, S | 1 |
| Agarwal, R; Dhanalakshmi, S; Mallikarjuna, GU; Singh, RP | 1 |
| Agarwal, C; Agarwal, R; Dhanalakshmi, S; Mallikarjuna, G; Singh, RP | 1 |
| Agarwal, C; Agarwal, R; Dhanalakshmi, S; Singh, RP | 1 |
| Agarwal, R; Dhanalakshmi, S; Gu, M; Singh, RP | 1 |
| Agarwal, R; Singh, RP | 1 |
| Agarwal, R; Dhanalakshmi, S; Gu, M; Mohan, S; Singh, RP | 1 |
| Agarwal, C; Agarwal, R; Dhanalakshmi, S; Gu, M; Singh, RP | 1 |
3 review(s) available for silybin and Cancer of Skin
| Article | Year |
|---|---|
Chemopreventive opportunities to control basal cell carcinoma: Current perspectives.
Topics: Animals; Antioxidants; Biological Products; Carcinoma, Basal Cell; Hedgehog Proteins; Humans; Silybin; Silymarin; Skin; Skin Neoplasms | 2015 |
Photochemoprevention of cutaneous neoplasia through natural products.
Topics: Animals; Anticarcinogenic Agents; Cat's Claw; Flavonoids; Humans; Phenols; Phytotherapy; Plant Preparations; Polyphenols; Polypodium; Silybin; Silymarin; Skin Neoplasms; Ultraviolet Rays | 2009 |
Mechanisms and preclinical efficacy of silibinin in preventing skin cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Communication; Cell Cycle; Cell Proliferation; Dermatitis; DNA Damage; Humans; Mice; Mitogens; Silybin; Silymarin; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays | 2005 |
15 other study(ies) available for silybin and Cancer of Skin
| Article | Year |
|---|---|
Chemopreventive efficacy of silibinin against basal cell carcinoma growth and progression in UVB-irradiated Ptch+/- mice.
Topics: Animals; Carcinoma, Basal Cell; Female; Hedgehog Proteins; Male; Mice; Patched-1 Receptor; Silybin; Skin Neoplasms; Ultraviolet Rays | 2022 |
Functionalized Caprolactone-Polyethylene Glycol Based Thermo-Responsive Hydrogels of Silibinin for the Treatment of Malignant Melanoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Caproates; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Hydrogels; Lactones; Melanoma; Melanoma, Cutaneous Malignant; Mice; Mice, Inbred C57BL; Molecular Structure; Polyethylene Glycols; Silybin; Skin Neoplasms; Temperature | 2018 |
Silibinin inhibits ultraviolet B radiation-induced mast cells recruitment and bone morphogenetic protein 2 expression in the skin at early stages in Ptch(+/-) mouse model of basal cell carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Bone Morphogenetic Protein 2; Carcinoma, Basal Cell; Chemoprevention; Cyclin D1; Disease Models, Animal; DNA Damage; Mast Cells; Mice; Mice, Transgenic; Patched-1 Receptor; Signal Transduction; Silybin; Skin; Skin Neoplasms; Tumor Suppressor Proteins; Ultraviolet Rays | 2019 |
p53-mediated autophagy adjustment is involved in the protection of silibinin against murine dermal inflammation and epidermal apoptosis induced by UVB irradiation.
Topics: Animals; Apoptosis; Autophagy; Epidermis; Epithelial Cells; Inflammation; Male; Mice; Molecular Structure; Silybin; Silymarin; Skin Neoplasms; Tumor Suppressor Protein p53 | 2013 |
Silibinin and its 2,3-dehydro-derivative inhibit basal cell carcinoma growth via suppression of mitogenic signaling and transcription factors activation.
Topics: Allografts; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Carcinoma, Basal Cell; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Enzyme Activation; Humans; Mice; Mice, Knockout; NF-kappa B; Signal Transduction; Silybin; Silymarin; Skin Neoplasms; Transcription Factor AP-1; Transcription Factors; Tumor Stem Cell Assay | 2016 |
Pro-Oxidant Role of Silibinin in DMBA/TPA Induced Skin Cancer: 1H NMR Metabolomic and Biochemical Study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Catalase; In Situ Nick-End Labeling; Magnetic Resonance Spectroscopy; Male; Metabolomics; Mice; Reactive Oxygen Species; Silybin; Silymarin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2016 |
Role of p53 in silibinin-mediated inhibition of ultraviolet B radiation-induced DNA damage, inflammation and skin carcinogenesis.
Topics: Animals; Antioxidants; Cell Transformation, Neoplastic; DNA Damage; Female; Inflammation; Male; Mice; Mice, Hairless; Mice, Inbred C57BL; Mice, Knockout; Silybin; Silymarin; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays | 2017 |
Silibinin Treatment Inhibits the Growth of Hedgehog Inhibitor-Resistant Basal Cell Carcinoma Cells via Targeting EGFR-MAPK-Akt and Hedgehog Signaling.
Topics: Antineoplastic Agents; Carcinoma, Basal Cell; Cell Death; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Hedgehog Proteins; Humans; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Silybin; Skin Neoplasms | 2017 |
Silibinin prevents ultraviolet B radiation-induced epidermal damages in JB6 cells and mouse skin in a p53-GADD45α-dependent manner.
Topics: Animals; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Mice; Mice, Hairless; Nuclear Proteins; Pyrimidine Dimers; RNA Interference; RNA, Small Interfering; S Phase Cell Cycle Checkpoints; Silybin; Silymarin; Skin; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays | 2012 |
Silibinin prevents ultraviolet radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dimerization; DNA Damage; Epidermis; Female; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Hairless; Models, Biological; Proliferating Cell Nuclear Antigen; Pyrimidine Dimers; Silybin; Silymarin; Skin; Skin Neoplasms; Time Factors; Tumor Suppressor Protein p53; Ultraviolet Rays; Up-Regulation | 2004 |
Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling.
Topics: Administration, Oral; Administration, Topical; Animals; Apoptosis; Bromodeoxyuridine; Caspase 3; Caspases; Cell Cycle Proteins; Cell Division; Enzyme Activation; Female; MAP Kinase Signaling System; Mice; Mice, Hairless; Mitogen-Activated Protein Kinases; Neoplasms, Radiation-Induced; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Silybin; Silymarin; Skin; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays; Up-Regulation | 2004 |
Silibinin up-regulates DNA-protein kinase-dependent p53 activation to enhance UVB-induced apoptosis in mouse epithelial JB6 cells.
Topics: Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Caspase 3; Caspases; Cell Cycle Proteins; Cell Line; Chromones; DNA; DNA Damage; DNA-Binding Proteins; Enzyme Activation; Epithelial Cells; ets-Domain Protein Elk-1; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Intracellular Signaling Peptides and Proteins; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Silybin; Silymarin; Skin Neoplasms; Transcription Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Ultraviolet Rays | 2005 |
Dietary feeding of silibinin prevents early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis.
Topics: Animals; Apoptosis; Cell Proliferation; Chemoprevention; Dietary Supplements; DNA Damage; DNA Repair; Epidermis; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Hairless; Models, Animal; Pyrimidine Dimers; Silybin; Silymarin; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays | 2005 |
Differential effect of silibinin on E2F transcription factors and associated biological events in chronically UVB-exposed skin versus tumors in SKH-1 hairless mice.
Topics: Animals; Apoptosis; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; E2F Transcription Factors; Female; Mice; Mice, Hairless; Signal Transduction; Silybin; Silymarin; Skin; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays | 2006 |
Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice.
Topics: Animals; Antioxidants; Cell Growth Processes; Cell Nucleus; Cell Transformation, Neoplastic; Cyclooxygenase 2; Female; Inflammation; Mice; Mice, Hairless; Neovascularization, Pathologic; NF-kappa B; Nitric Oxide Synthase Type II; Phosphorylation; Silybin; Silymarin; Skin; Skin Neoplasms; STAT3 Transcription Factor; Ultraviolet Rays | 2007 |