silybin has been researched along with Breast Neoplasms in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (17.50) | 29.6817 |
| 2010's | 26 (65.00) | 24.3611 |
| 2020's | 7 (17.50) | 2.80 |
| Authors | Studies |
|---|---|
| Motamed, N; Ranapour, S | 1 |
| Feng, NP; Gu, XY; Liu, Y; Shi, JP; Sun, YW; Zhang, RG | 1 |
| Binienda, A; Pluciennik, E; Ziolkowska, S | 1 |
| He, K; Jiang, M; Liu, Q; Qiu, T; Sun, J; Zhang, X; Zheng, H | 1 |
| Chen, H; Feng, N; He, Y; Hou, X; Liu, Y; Shen, J; Shi, J; Wang, Z; Xie, X | 1 |
| Fu, J; Hayashi, T; Ikejima, T; Ji, Y; Liu, W; Onodera, S; Si, L; Sun, Y | 1 |
| Dadashpour, M; Firouzi Amandi, A; Mousapour, A; Pourgholi, A; Zarghami, N | 1 |
| Hakamivala, A; Kashanian, S; Maharat, Z; Moghassemi, S; Omidfar, K; Yazdi Rouholamini, SE | 1 |
| Dong, XY; Lang, TQ; Li, YP; Yin, Q; Zhang, PC | 1 |
| Asbaghi, N; Chatran, M; Dadashpour, M; Faramarzi, L; Jafari-Gharabaghlou, D; Pilehvar-Soltanahmadi, Y; Rasouli, S; Zarghami, N | 1 |
| Chen, L; Li, Y; Shen, J; Xu, P; Yin, Q; Yu, H; Zhang, Z | 1 |
| Alibakhshi, A; Barkhordari, A; Esfahlan, RJ; Koshki, KN; Moghaddam, MP; Mollazadeh, M; Nasiri, M; Yamchi, MR; Zarghami, N | 1 |
| Abhari, A; Akbarzadeh, A; Dariushnejad, H; Nejati-Koshki, K; Pourhasan-Moghaddam, M | 1 |
| Kim, KH; Kim, TH; Kim, YK; Woo, JS | 1 |
| Alimoghaddam, K; Ghaffari, SH; Ghavamzadeh, A; Hassani, S; Yousefi, M; Zekri, A | 1 |
| Bosch-Barrera, J; Brunet, J; Corominas-Faja, B; Cuyàs, E; Martin-Castillo, B; Menendez, JA | 1 |
| Abdollahi, P; Ebrahimi, M; Motamed, N; Samani, FS | 1 |
| Ji, Z; Jiang, K; Jin, X; Meng, G; Wang, W; Wang, Z | 1 |
| Hayashi, T; Huang, H; Ikejima, T; Liu, L; Liu, W; Onodera, S; Tashiro, S; Xia, M; Zang, L; Zhang, P; Zhang, Y; Zheng, N | 1 |
| Aristarco, V; Bonanni, B; Caldarella, P; Cazzaniga, M; DeCensi, A; Gandini, S; Guerrieri-Gonzaga, A; Johansson, H; Lazzeroni, M; Mora, S; Morazzoni, P; Pagani, G; Petrangolini, G; Pruneri, G; Puccio, A; Riva, A; Serrano, D | 1 |
| Li, YP; Meng, QS; Su, JH; Sun, HP; Wang, SL; Yin, Q; Yu, HJ; Zhang, PC; Zhang, ZW | 1 |
| Bakhshandeh, B; Jahanafrooz, Z; Motameh, N | 1 |
| Bayram, D; Candan, IA; Çetin, ES; Kara, M; Özgöçmen, M | 1 |
| Akbarzadeh, A; Amiri, B; Chiani, M; Ebrahimi-Far, M; Saffari, Z; Soleimani, E | 1 |
| Hayashi, T; Ikejima, T; Li, F; Liu, L; Liu, WW; Onodera, S; Tashiro, SI; Zheng, N | 1 |
| Asiaee, F; Hejazi, M; Lai, R; Molavi, O; Narimani, F; Sharifi, S; Shayanfar, A; Tarhriz, V | 1 |
| Ikejima, T; Onodera, S; Tashiro, S; Wang, HJ | 1 |
| Choe, JH; Choi, JH; Kim, JH; Kim, JS; Kim, S; Kim, WW; Lee, JE; Lee, SK; Lim, HI; Nam, SJ; Yang, JH | 1 |
| Lin, CJ; Pelletier, J; Sukarieh, R | 1 |
| Choe, JH; Hur, SM; Kim, JH; Kim, JS; Kim, S; Kim, SH; Kim, WW; Lee, JE; Lee, SK; Nam, SJ; Yang, JH | 1 |
| Huang, H; Ikejima, T; Jiang, YY; Onodera, S; Tashiro, S; Wang, HJ; Wei, XF | 1 |
| Fan, SM; Huang, H; Ikejima, T; Jiang, YY; Onodera, S; Tashiro, S; Wang, HJ; Wei, XF; Yang, Y; Zang, LH | 1 |
| Balakrishnan, S; Kumar, A; Kushwaha, HS; Mishra, KP; Tiwari, P | 1 |
| Azadmanesh, K; Dastpeyman, M; Jahanian-Najafabadi, A; Kia, V; Mostafavi, E; Motamed, N; Shokrgozar, MA | 1 |
| Choe, JH; Han, J; Kim, JH; Kim, JS; Kim, S; Lee, JE; Nam, SJ; Yang, JH | 1 |
| Chen, H; King, TD; Li, Y; Lin, C; Lu, W; Reynolds, RC | 1 |
| Han, J; Jung, SP; Kim, JH; Kim, JS; Kim, S; Lee, JE; Nam, SJ; Oh, SJ | 1 |
| Agarwal, C; Agarwal, R; Chan, DC; Tyagi, AK | 1 |
| Chang, YC; Im, HG; Jeong, YJ; Kim, CH; Lee, IS; Lee, SO | 1 |
| Agarwal, R; Raina, K | 1 |
2 review(s) available for silybin and Breast Neoplasms
| Article | Year |
|---|---|
The Anticancer Properties of Silibinin: Its Molecular Mechanism and Therapeutic Effect in Breast Cancer.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Humans; Molecular Structure; Silybin | 2020 |
Combinatorial strategies for cancer eradication by silibinin and cytotoxic agents: efficacy and mechanisms.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cytotoxins; Female; Humans; Lung Neoplasms; Male; Neoplasms; Prostatic Neoplasms; Silybin; Silymarin | 2007 |
1 trial(s) available for silybin and Breast Neoplasms
| Article | Year |
|---|---|
A Presurgical Study of Oral Silybin-Phosphatidylcholine in Patients with Early Breast Cancer.
Topics: Administration, Oral; Antineoplastic Agents; Biological Availability; Biomarkers, Tumor; Breast Neoplasms; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydrolysis; Middle Aged; Phosphatidylcholines; Reproducibility of Results; Silybin; Silymarin; Tandem Mass Spectrometry | 2016 |
37 other study(ies) available for silybin and Breast Neoplasms
| Article | Year |
|---|---|
Effect of Silibinin on the Expression of Mir-20b, Bcl2L11, and Erbb2 in Breast Cancer Cell Lines.
Topics: Apoptosis; Breast Neoplasms; Caspase 9; Cell Line, Tumor; Cell Proliferation; Female; Humans; MCF-7 Cells; MicroRNAs; Receptor, ErbB-2; Silybin | 2023 |
[Effects of Platycodonis Radix-Curcumae Rhizoma on oral nanoparticle uptake and in vitro inhibition against breast cancer metastasis].
Topics: Animals; Breast Neoplasms; Caco-2 Cells; Cell Line, Tumor; Female; Humans; Melanoma, Cutaneous Malignant; Mice; Nanoparticles; Polymers; Silybin; Tumor Microenvironment | 2023 |
Tumor-targeted delivery of silibinin and IPI-549 synergistically inhibit breast cancer by remodeling the microenvironment.
Topics: Administration, Intravenous; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Breast Neoplasms; Cancer-Associated Fibroblasts; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Isoquinolines; Mice; Nanoparticles; Polyesters; Polyethylene Glycols; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Silybin; Tumor Microenvironment | 2020 |
Functional oral nanoparticles for delivering silibinin and cryptotanshinone against breast cancer lung metastasis.
Topics: Animals; Antineoplastic Agents; Biological Availability; Breast Neoplasms; Caco-2 Cells; Cell Movement; HT29 Cells; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mucus; Nanoparticles; Neoplasms, Experimental; Phenanthrenes; Rats, Sprague-Dawley; Silybin; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2020 |
Estrogen receptors participate in silibinin-caused nuclear translocation of apoptosis-inducing factor in human breast cancer MCF-7 cells.
Topics: Active Transport, Cell Nucleus; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Inducing Factor; Breast Neoplasms; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Humans; MCF-7 Cells; Silybin | 2020 |
Anticancer Potential of Silibinin Loaded Polymeric Nanoparticles against Breast Cancer Cells: Insight into the Apoptotic Genes Targets.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Drug Carriers; Drug Liberation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Nanoparticles; Polymers; Silybin; Tumor Cells, Cultured | 2021 |
Effect of silibinin-loaded nano-niosomal coated with trimethyl chitosan on miRNAs expression in 2D and 3D models of T47D breast cancer cell line.
Topics: Breast Neoplasms; Cell Line, Tumor; Chitosan; Coated Materials, Biocompatible; Drug Carriers; Female; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Nanoparticles; RNA, Neoplasm; Silybin; Silymarin | 2018 |
Co-delivery of docetaxel and silibinin using pH-sensitive micelles improves therapy of metastatic breast cancer.
Topics: Acrylic Resins; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Proliferation; Docetaxel; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Hydrogen-Ion Concentration; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Polyethylene Glycols; Silybin; Silymarin; Structure-Activity Relationship; Taxoids; Tumor Cells, Cultured | 2017 |
Synergistic Anti-proliferative Effects of Metformin and Silibinin Combination on T47D Breast Cancer Cells via hTERT and Cyclin D1 Inhibition.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Drug Screening Assays, Antitumor; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Metformin; Silybin; Telomerase | 2018 |
Synergistic inhibition of breast cancer metastasis by silibinin-loaded lipid nanoparticles containing TPGS.
Topics: Animals; Antineoplastic Agents; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Carriers; Drug Synergism; Female; Humans; Lung Neoplasms; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Nude; Nanoparticles; Neoplasm Invasiveness; Particle Size; Phosphatidylcholines; Polyethylene Glycols; Silybin; Silymarin; Snail Family Transcription Factors; Solubility; Technology, Pharmaceutical; Time Factors; Tissue Distribution; Transcription Factors; Vitamin E; Wound Healing; Xenograft Model Antitumor Assays | 2013 |
Curcumin and silibinin inhibit telomerase expression in T47D human breast cancer cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Breast Neoplasms; Cell Proliferation; Curcumin; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Silybin; Silymarin; Telomerase; Tumor Cells, Cultured | 2013 |
Inhibition of leptin and leptin receptor gene expression by silibinin-curcumin combination.
Topics: Antineoplastic Agents; Antioxidants; Breast Neoplasms; Cell Proliferation; Curcumin; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Neoplastic; Humans; Leptin; Real-Time Polymerase Chain Reaction; Receptors, Leptin; Signal Transduction; Silybin; Silymarin | 2014 |
Silibinin induces cell death through reactive oxygen species-dependent downregulation of notch-1/ERK/Akt signaling in human breast cancer cells.
Topics: Active Transport, Cell Nucleus; Antineoplastic Agents; Antioxidants; Apoptosis Inducing Factor; Breast Neoplasms; Caspase 3; Cell Death; Cell Line, Tumor; Cell Nucleus; Down-Regulation; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptor, Notch1; Signal Transduction; Silybin; Silymarin | 2014 |
Silibinin induces apoptosis and inhibits proliferation of estrogen receptor (ER)-negative breast carcinoma cells through suppression of nuclear factor kappa B activation.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; NF-kappa B; Phosphorylation; Real-Time Polymerase Chain Reaction; Silybin; Silymarin | 2014 |
Silibinin administration improves hepatic failure due to extensive liver infiltration in a breast cancer patient.
Topics: Adult; Breast Neoplasms; Female; Humans; Liver; Liver Failure; Silybin; Silymarin; Vitamin E | 2014 |
Silibinin affects tumor cell growth because of reduction of stemness properties and induction of apoptosis in 2D and 3D models of MDA-MB-468.
Topics: Anticarcinogenic Agents; Antioxidants; Apoptosis; Breast Neoplasms; Cell Culture Techniques; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Humans; Neoplastic Stem Cells; Silybin; Silymarin | 2015 |
Silibinin, a natural flavonoid, induces autophagy via ROS-dependent mitochondrial dysfunction and loss of ATP involving BNIP3 in human MCF7 breast cancer cells.
Topics: Adenosine Triphosphate; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Breast Neoplasms; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Membrane Proteins; Mitochondria; Proto-Oncogene Proteins; Reactive Oxygen Species; Signal Transduction; Silybin; Silymarin | 2015 |
ERα down-regulation plays a key role in silibinin-induced autophagy and apoptosis in human breast cancer MCF-7 cells.
Topics: Apoptosis; Autophagy; Breast Neoplasms; Down-Regulation; Estrogen Receptor alpha; Female; Gene Expression; Humans; MAP Kinase Signaling System; MCF-7 Cells; Silybin; Silymarin; TOR Serine-Threonine Kinases | 2015 |
Silibinin and indocyanine green-loaded nanoparticles inhibit the growth and metastasis of mammalian breast cancer cells in vitro.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Liberation; Female; Humans; Indocyanine Green; Nanoparticles; Neoplasm Metastasis; Particle Size; Silybin; Silymarin; Wound Healing | 2016 |
Comparative Evaluation of Silibinin Effects on Cell Cycling and Apoptosis in Human Breast Cancer MCF-7 and T47D Cell Lines.
Topics: Antioxidants; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Proliferation; Female; Humans; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Silybin; Silymarin; Tumor Cells, Cultured | 2016 |
The apoptotic effects of silibinin on MDA-MB-231 and MCF-7 human breast carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Humans; In Situ Nick-End Labeling; Poly(ADP-ribose) Polymerases; Silybin; Silymarin; Spheroids, Cellular | 2017 |
Preparation, Characterization and Cytotoxicity of Silibinin- Containing Nanoniosomes in T47D Human Breast Carcinoma Cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Drug Delivery Systems; Female; Humans; Liposomes; Nanoparticles; Particle Size; Silybin; Silymarin | 2016 |
Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro.
Topics: Adenine; Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; Reactive Nitrogen Species; Reactive Oxygen Species; Silybin; Silymarin; Up-Regulation | 2017 |
Silibinin sensitizes chemo-resistant breast cancer cells to chemotherapy.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; MAP Kinase Signaling System; Paclitaxel; Silybin; Silymarin; STAT3 Transcription Factor | 2017 |
Inhibition of insulin-like growth factor 1 receptor signaling enhanced silibinin-induced activation of death receptor and mitochondrial apoptotic pathways in human breast cancer MCF-7 cells.
Topics: Apoptosis; Breast Neoplasms; Female; Humans; Mitochondria; Receptor, IGF Type 1; Receptors, Death Domain; Signal Transduction; Silybin; Silymarin; Tumor Cells, Cultured | 2008 |
Silibinin prevents TPA-induced MMP-9 expression and VEGF secretion by inactivation of the Raf/MEK/ERK pathway in MCF-7 human breast cancer cells.
Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Phosphorylation; Protein Kinase Inhibitors; Silybin; Silymarin; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2009 |
Silibinin inhibits translation initiation: implications for anticancer therapy.
Topics: Antineoplastic Agents; Antioxidants; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cyclin D1; Dose-Response Relationship, Drug; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4F; Fluorescent Antibody Technique; Humans; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Protein Biosynthesis; Protein Transport; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Silybin; Silymarin; TOR Serine-Threonine Kinases; Transcription Factors; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2009 |
Silibinin prevents TPA-induced MMP-9 expression by down-regulation of COX-2 in human breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Breast Neoplasms; Butadienes; Celecoxib; Cell Line, Tumor; Cyclooxygenase 2; Down-Regulation; Humans; MAP Kinase Kinase Kinases; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Nitriles; Phytotherapy; Protein Kinase Inhibitors; Pyrazoles; Seeds; Silybin; Silybum marianum; Silymarin; Sulfonamides; Tetradecanoylphorbol Acetate | 2009 |
Silibinin induces protective superoxide generation in human breast cancer MCF-7 cells.
Topics: Antioxidants; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cytoprotection; Drug Evaluation, Preclinical; Feedback, Physiological; Female; Homeostasis; Humans; Mitochondria; Models, Biological; p38 Mitogen-Activated Protein Kinases; Protein-Tyrosine Kinases; Reactive Oxygen Species; Silybin; Silymarin; Superoxides; Up-Regulation | 2010 |
Silibinin induces the generation of nitric oxide in human breast cancer MCF-7 cells.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Breast Neoplasms; Caenorhabditis elegans; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Leukocytes, Mononuclear; Mice; Nitric Oxide; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species; Silybin; Silymarin; Time Factors; Tumor Cells, Cultured | 2010 |
Silibinin-induced apoptosis in MCF7 and T47D human breast carcinoma cells involves caspase-8 activation and mitochondrial pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 8; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Female; Humans; Membrane Potential, Mitochondrial; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Silybin; Silymarin; Time Factors | 2011 |
Inhibition of silibinin on migration and adhesion capacity of human highly metastatic breast cancer cell line, MDA-MB-231, by evaluation of β1-integrin and downstream molecules, Cdc42, Raf-1 and D4GDI.
Topics: Antioxidants; Breast Neoplasms; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Integrin beta1; Neoplasm Metastasis; Proto-Oncogene Proteins c-raf; rho Guanine Nucleotide Dissociation Inhibitor beta; RNA, Messenger; Silybin; Silymarin | 2012 |
Silibinin suppresses EGFR ligand-induced CD44 expression through inhibition of EGFR activity in breast cancer cells.
Topics: Antioxidants; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Hyaluronan Receptors; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Real-Time Polymerase Chain Reaction; RNA, Messenger; Silybin; Silymarin; Transforming Growth Factor alpha | 2011 |
Silibinin inhibits Wnt/β-catenin signaling by suppressing Wnt co-receptor LRP6 expression in human prostate and breast cancer cells.
Topics: Antineoplastic Agents; beta Catenin; Breast Neoplasms; Cell Line, Tumor; Female; HEK293 Cells; Humans; Low Density Lipoprotein Receptor-Related Protein-6; Male; Phosphorylation; Prostatic Neoplasms; Signal Transduction; Silybin; Silymarin; Wnt Proteins | 2012 |
Silibinin inhibits TPA-induced cell migration and MMP-9 expression in thyroid and breast cancer cells.
Topics: Breast Neoplasms; Butadienes; Cell Movement; Female; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 9; MCF-7 Cells; Neoplasm Invasiveness; Nitriles; Phosphorylation; Silybin; Silymarin; Tetradecanoylphorbol Acetate; Thyroid Neoplasms | 2013 |
Synergistic anti-cancer effects of silibinin with conventional cytotoxic agents doxorubicin, cisplatin and carboplatin against human breast carcinoma MCF-7 and MDA-MB468 cells.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Carboplatin; Cell Division; Cell Line, Tumor; Cell Survival; Cisplatin; Doxorubicin; Drug Synergism; Female; Humans; Kinetics; Silybin; Silybum marianum; Silymarin | 2004 |
Silibinin suppresses PMA-induced MMP-9 expression by blocking the AP-1 activation via MAPK signaling pathways in MCF-7 human breast carcinoma cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Combinations; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Silybin; Silymarin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 2007 |