silybin has been researched along with Bladder Cancer in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Almeida, TC; Barros, TMB; da Silva, GN; Lima, APB | 1 |
| Cheng, Y; Guan, Z; Jiang, Y; Li, Q; Sun, Y; Xu, Y; Zhao, W | 1 |
| Balarino, N; Belgorosky, D; Eiján, AM; Langle, Y; Prack Mc Cormick, B; Sandes, E; Vanzulli, S | 1 |
| Chang, L; Chen, Y; Guo, P; He, D; Jia, J; Jin, B; Li, F; Ma, Z; Sun, Y; Tang, X; Wang, K; Wang, X; Yang, C; Zeng, J | 1 |
| Hadjipavlou, M; Khan, S; Philippou, Y; Rane, A | 1 |
| Chen, Y; Fan, J; Gao, Y; Guo, P; He, D; Li, L; Ning, Z; Wang, B; Wang, X; Wu, K; Zeng, J; Zhang, L; Zhang, T; Zhou, J | 1 |
| Batlle, A; Casas, A; Di Venosa, G; Eiján, AM; Gándara, L; Mamone, L; Prack Mc Cormick, B; Rodriguez, L; Sandes, E | 1 |
| Barbosa, LC; Barros, TM; DA Silva, GN; DE Oliveira, DT; Marcondes, JP; Salvadori, DM; Savio, AL | 1 |
| Chen, Y; He, D; Li, L; Sun, Y; Wang, X; Wang, Z; Wu, K; Xue, Y; Yang, Z; Zeng, J; Zhang, D; Zhang, G; Zhu, G | 1 |
| Agarwal, C; Agarwal, R; Glode, LM; Shroyer, KR; Singh, RP; Tyagi, AK | 1 |
| Agarwal, C; Agarwal, R; Glode, LM; Harrison, G; Tyagi, A | 1 |
| Agarwal, C; Agarwal, R; Singh, RP; Tyagi, A | 1 |
| Agarwal, C; Agarwal, R; Glode, LM; Gu, M; Harrison, G; Raina, K; Singh, RP; Tyagi, A | 1 |
| Agarwal, R; Mohan, S; Sharma, G; Singh, RP; Tyagi, A | 1 |
1 review(s) available for silybin and Bladder Cancer
| Article | Year |
|---|---|
Complementary and alternative medicine (CAM) in prostate and bladder cancer.
Topics: Acupuncture; Antineoplastic Agents; Antioxidants; Camellia sinensis; Complementary Therapies; Drugs, Chinese Herbal; Female; Humans; Male; Plant Extracts; Prostatic Neoplasms; Resveratrol; Selenium; Silybin; Silymarin; Stilbenes; Urinary Bladder Neoplasms; Vitamin E; Vitamins | 2013 |
13 other study(ies) available for silybin and Bladder Cancer
| Article | Year |
|---|---|
Inhibition of urinary bladder cancer cell proliferation by silibinin.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Silybin; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms | 2020 |
Silibinin suppresses bladder cancer cell malignancy and chemoresistance in an NF-κB signal-dependent and signal-independent manner.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Cisplatin; Disease Progression; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Humans; Neoplasm Invasiveness; NF-kappa B; Signal Transduction; Silybin; Silymarin; Urinary Bladder Neoplasms | 2017 |
Flavonoid silybin improves the response to radiotherapy in invasive bladder cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Gamma Rays; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Radiation-Sensitizing Agents; Silybin; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 2018 |
Silibinin attenuates TGF‑β1‑induced migration and invasion via EMT suppression and is associated with COX‑2 downregulation in bladder transitional cell carcinoma.
Topics: Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Invasiveness; Silybin; Transforming Growth Factor beta1; Urinary Bladder Neoplasms | 2018 |
Silibinin inhibits β-catenin/ZEB1 signaling and suppresses bladder cancer metastasis via dual-blocking epithelial-mesenchymal transition and stemness.
Topics: Animals; Anticarcinogenic Agents; beta Catenin; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; Homeodomain Proteins; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplastic Stem Cells; Signal Transduction; Silybin; Silybum marianum; Silymarin; Transcription Factors; Urinary Bladder; Urinary Bladder Neoplasms; Zinc Finger E-box-Binding Homeobox 1 | 2013 |
The natural flavonoid silybin improves the response to Photodynamic Therapy of bladder cancer cells.
Topics: Aminolevulinic Acid; Apoptosis; Cell Line, Tumor; Cell Movement; Drug Synergism; Drug Therapy, Combination; Flavonoids; Humans; Light; Photochemotherapy; Photosensitizing Agents; Silybin; Silybum marianum; Silymarin; Urinary Bladder Neoplasms | 2014 |
Cytotoxic and toxicogenomic effects of silibinin in bladder cancer cells with different TP53 status.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Proto-Oncogene Proteins c-akt; Receptor, Fibroblast Growth Factor, Type 3; Silybin; Silymarin; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms | 2017 |
Chemopreventive and chemotherapeutic effects of intravesical silibinin against bladder cancer by acting on mitochondria.
Topics: Administration, Intravesical; Animals; Antioxidants; Apoptosis; Apoptosis Inducing Factor; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Survival; Cytochromes c; Down-Regulation; Female; High-Temperature Requirement A Serine Peptidase 2; Humans; Inhibitor of Apoptosis Proteins; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Mitochondrial Proteins; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Silybin; Silymarin; Survivin; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2011 |
Silibinin down-regulates survivin protein and mRNA expression and causes caspases activation and apoptosis in human bladder transitional-cell papilloma RT4 cells.
Topics: Apoptosis; Carcinoma, Transitional Cell; Caspases; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Neoplasm Proteins; Papilloma; RNA, Messenger; Silybin; Silymarin; Survivin; Urinary Bladder Neoplasms | 2003 |
Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages.
Topics: Apoptosis; Carcinoma, Transitional Cell; Caspase 3; Caspases; Cell Cycle; Cell Cycle Proteins; Cell Division; Cyclins; Humans; Poly(ADP-ribose) Polymerases; Silybin; Silybum marianum; Silymarin; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 2004 |
Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for a regulatory loop between p53 and caspase 2.
Topics: Apoptosis; Benzothiazoles; Caspase 2; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes c; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Mitochondria; Models, Biological; Silybin; Silymarin; Toluene; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms | 2006 |
Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Butylhydroxybutylnitrosamine; Carcinogens; Cell Proliferation; Cyclin D1; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Phosphorylation; Silybin; Silymarin; Urinary Bladder Neoplasms | 2007 |
Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Transitional Cell; Cell Proliferation; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Male; Mice; Mice, Nude; Microtubule-Associated Proteins; Neovascularization, Pathologic; Repressor Proteins; Silybin; Silymarin; Survivin; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2008 |