silicon-nitride and Influenza--Human

Rapid diagnosis of flu before symptom onsets can revolutionize our health through diminishing a risk for serious complication as well as preventing infectious disease outbreak. Sensor sensitivity and selectivity are key to accomplish this goal as the number of virus is quite small at the early stage of infection. Here we report on label-free electrical diagnostics of influenza based on nanopore analytics that distinguishes individual virions by their distinct physical features. We accomplish selective resistive-pulse sensing of single flu virus having negative surface charges in a physiological media by exploiting electroosmotic flow to filter contaminants at the Si

Topics: Electricity; Humans; Influenza A virus; Influenza, Human; Ion Transport; Machine Learning; Nanopores; Nanotechnology; Point-of-Care Systems; Sensitivity and Specificity; Silicon Compounds