silicon-nitride has been researched along with Heart-Failure* in 1 studies
1 other study(ies) available for silicon-nitride and Heart-Failure
| Article | Year |
|---|---|
A silicon nitride ISFET based immunosensor for tumor necrosis factor-alpha detection in saliva. A promising tool for heart failure monitoring.
According to the European statistics, approximately 26 million patients worldwide suffer from heart failure (HF), and this number seems to be steadily increasing. Inflammation plays a central role in the development of HF, and the pro-inflammatory cytokine Tumor necrosis factor-α (TNF-α) represents inflammation gold-standard biomarker. Early detection plays a crucial role for the prognosis and treatment of HF. An Ion Sensitive Field Effect Transistor (ISFET) based on silicon nitride transducer and biofunctionalized with anti-TNF-α antibody for label-free detection of salivary TNF-α is proposed. Electrochemical impedance spectroscopy (EIS) was used for TNF-α detection. Our ImmunoFET offered a detection limit of 1 pg mL Topics: Biosensing Techniques; Heart Failure; Humans; Immunoassay; Reproducibility of Results; Saliva; Silicon Compounds; Tumor Necrosis Factor-alpha | 2021 |