silicon and Premature-Birth

silicon has been researched along with Premature-Birth* in 1 studies

Other Studies

1 other study(ies) available for silicon and Premature-Birth

ArticleYear
Device Fabrication and Fluorescent Labeling of Preterm Birth Biomarkers for Microchip Electrophoresis.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1972

    An unmet need exists for a clinical diagnostic to determine preterm birth (PTB) risk. Such an assessment is possible with high sensitivity and specificity using a panel of nine biomarkers. An integrated microfluidic analysis system for these biomarkers is being developed which includes microchip electrophoresis (μCE) separation. A t-shaped microchip device can be used to test the μCE portion of this integrated system to find appropriate separation conditions. These t-shaped microchips can be fabricated using photolithographically patterned Si templates and hot embossing. PTB biomarkers can be fluorescently labeled using an amine-reactive dye prior to μCE. The μCE conditions established using this t-shaped device should be useful in developing a complete integrated microfluidic system for PTB risk assessment.

    Topics: Biomarkers; Electrodes; Electrophoresis, Microchip; Fluorescent Dyes; Humans; Premature Birth; Silicon

2019