silicon and Pleural-Diseases

silicon has been researched along with Pleural-Diseases* in 3 studies

Reviews

1 review(s) available for silicon and Pleural-Diseases

ArticleYear
Human epidemiology: a review of fiber type and characteristics in the development of malignant and nonmalignant disease.
    Environmental health perspectives, 1990, Volume: 88

    Consideration of the human epidemiology of diseases arising from exposure to naturally occurring and man-made mineral fibers encompasses the several forms of asbestos (chrysotile, crocidolite, amosite, anthophyllite, tremolite-actinolite), other naturally occurring silicates (talc, sepiolite, erionite, attapulgite, vermiculite, and wollastonite), and man-made mineral fibers (glass continuous filament, glass/rock/slag insulation wools, ceramic and other refractory fibers, and glass microfibers). The diseases arising from exposures to some of these fibers include pleural thickening (plaques, diffuse pleural thickening, and calcification), pulmonary fibrosis, lung cancers, mesothelioma of the pleura and peritoneum, and other cancers). Risk factors important in assessing these diseases include assessment of latency, duration of exposure, cumulative exposure, fiber origin and characteristics (length and diameter), other possible confounding occupational or environmental exposures, and smoking. Methodological issues commonly presenting problems in evaluation of these data include assessment of the adequacy of environmental exposures, particularly in regard to fiber identification, distribution, and concentration over the duration of exposure, and the adequacy of study design to detect health effects (disease frequency, latency, and cohort size). Research priorities include further assessment and standardization of pleural thickening relative to fiber exposure, uniform mesothelioma surveillance, further epidemiological assessment of certain silicate and man-made mineral fiber cohorts with emphasis given to assessment of tremolite and small diameter glass and ceramic fibers. Further assessment of possible health risks of the general public should await improved definition of relevant fiber exposure in ambient air.

    Topics: Asbestos; Asbestosis; Humans; Lung Neoplasms; Mesothelioma; Minerals; Neoplasms; Pleural Diseases; Respiratory Tract Diseases; Silicon

1990

Other Studies

2 other study(ies) available for silicon and Pleural-Diseases

ArticleYear
[Spectra study on the varied features of crocidolite fibers in rat].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2004, Volume: 35, Issue:1

    To further study the pathogenic mechanism of crocidolite, the imperceptible changes of crocidolite surface in rat were observed.. The animal model was established and the changes in the rat infected with dust were observed by use of microscopy, SEM, differential thermal analysis and IR spectroscopy.. In the course of interaction between organism protein and crocidolite, the protein symmetry decreased and structure loosened. The silicon of crocidolite was bonded with the alkyl, amido- of protein. New absorption bands of Si-O-C(N), Si-R clearly appeared. The organism cleared the dust by means of dissolution, enwrapping, winding or in the way of biochemical dissolution, and the fibre became shortened, broken, bifurcated, ends-rounded, and also it could dissolve, transfer and chemically react on surface.. The results showed that the surface radicals of asbestos fibre reacted with some albumen in tissue and hence formed new surface mediator. It is a new form of dissolution and reaction of fibre in vivo that fibres in alveoli transform to carbonate. The residual substances of crocidolite are mainly Si-O. Tissue membrane is the retardation cingulum of dust transference in vivo.

    Topics: Animals; Asbestos, Crocidolite; Asbestosis; Dust; Microscopy, Electron, Scanning; Mineral Fibers; Pleural Diseases; Pulmonary Fibrosis; Rats; Silicon

2004
Mechanisms of mesothelioma induction with asbestos and fibrous glass.
    Journal of the National Cancer Institute, 1972, Volume: 48, Issue:3

    Topics: Animals; Asbestos; Carcinogens; Female; Glass; Mesothelioma; Neoplasms, Experimental; Nickel; Pleural Diseases; Pleural Neoplasms; Rats; Silicon; Stainless Steel

1972