silicon has been researched along with Osteoporosis--Postmenopausal* in 3 studies
3 other study(ies) available for silicon and Osteoporosis--Postmenopausal
| Article | Year |
|---|---|
Short-term administration of water-soluble silicon improves mineral density of the femur and tibia in ovariectomized rats.
Silicon is important for the proper growth and development of bone and connective tissues. This study was designed to investigate if water-soluble silicon could be used for the treatment of postmenopausal osteoporosis. Silicon (Si 20 mg/kg body weight/day) was administrated orally to 17-week-old ovariectomized (OVX) rats for 4 weeks. Silicon did not alter weight gain in OVX rats. Silicon supplementation significantly increased the bone mineral density of the femur (p < 0.05, vs. OVX control group) and tibia in OVX rats (p < 0.05, vs. OVX control group). Serum alkaline phosphatase and osteocalcin, two bone formation biomarkers tested, were not significantly altered, but urinary calcium and phosphorous excretion tended to decrease with silicon supplementation. OVX rats with silicon supplementation showed a relatively higher serum CTx compared to the nonsupplemented OVX group (p < 0.01, vs. OVX control group). According to these results, short-term soluble silicon supplementation improved bone mineral density in OVX-induced osteoporosis. Topics: Alkaline Phosphatase; Animals; Biomarkers; Bone Density; Calcium; Dietary Supplements; Disease Models, Animal; Femur; Humans; Male; Osteocalcin; Osteoporosis, Postmenopausal; Ovariectomy; Rats; Rats, Sprague-Dawley; Silicon; Solubility; Tibia | 2008 |
[Avoid osteoporosis--eat silicon!].
Topics: Bone Density; Diet; Female; Humans; Male; Osteoporosis; Osteoporosis, Postmenopausal; Silicon | 2004 |
Effects of silicon, fluoride, etidronate and magnesium on bone mineral density: a retrospective study.
A retrospective study of bone mineral density (BMD) changes was performed in 53 osteoporotic women prior to carrying out a prospective study. Comparisons between BMD of controls (n = 16) and treated groups over a 14-22 month period showed that fluoride (n = 10) induced a significant (P < 0.05) increase in vertebral and a slight decrease in femoral BMD, whereas silicon (n = 8) induced a significant (P < 0.05) increase in femoral BMD. Etidronate (n = 13) and, to a lesser extent, magnesium (n = 6), induced a slight although statistically non-significant increase in vertebral BMD. Topics: Aged; Bone Density; Etidronic Acid; Female; Fluorides; Humans; Magnesium; Middle Aged; Osteoporosis, Postmenopausal; Retrospective Studies; Silicon | 1993 |