silicon and Metabolic-Diseases

Due to the importance of early detection of metabolic diseases in newborns, it is essential to measure organoacids; L-Tryptophan, Sebacic acid, and Glutaric acid in very low concentrations. Therefore, the necessity of the construction of a powerful nondestructive biosensor just like the surface-enhanced Raman scattering (SERS) sensor is demonstrated. Through the growth of silver dendritic nanostructures on different substrates like aluminum (Al), copper (Cu), indium tin oxide (ITO), and silicon (Si), a new SERS-based biosensor was developed. Because the Raman signal of molecules adsorbed on dendritic nanostructures is significantly increased, SERS biosensors based on these nanostructures can be used to detect very low concentrations of materials. In this study, first, the organoacid L-Lysine was detected up to a concentration of 10

Topics: Aluminum; Biosensing Techniques; Humans; Infant, Newborn; Metabolic Diseases; Metal Nanoparticles; Silicon; Silver; Spectrum Analysis, Raman; Tryptophan

Topics: Adrenal Gland Diseases; Adult; Androsterone; Catalysis; Chemistry, Clinical; Child; Chromatography, Gas; Clinical Laboratory Techniques; Dehydroepiandrosterone; Ethers; Etiocholanolone; Evaluation Studies as Topic; Female; Glass; Humans; Hydrolysis; Hyperplasia; Infant; Ketosteroids; Male; Mass Spectrometry; Metabolic Diseases; Methods; Oximes; Pregnanediol; Pregnanes; Pregnanetriol; Silicon; Steroids