silicon and Granuloma

Topics: Biochemical Phenomena; Biochemistry; Granuloma; Humans; Research; Silicon; Silicosis

Ga citrate is frequently used in the workup of fever of unknown origin. Here, we report a case of avid Ga-citrate in bilateral gluteal regions of a patient with a history of free silicon injection buttock augmentation referred for suspected diagnosis of sarcoidosis. CT findings were equivocal for inflammation/infection in the buttock region, and nuclear scintigraphy allowed for more definitive diagnosis.

Topics: Adult; Buttocks; Citrates; Diagnosis, Differential; Female; Gallium; Granuloma; Humans; Injections, Intramuscular; Radiopharmaceuticals; Sarcoidosis; Silicon

To explore the source of the fine particulate matter (PM(2.5)) in the sarcoidosis granulomatous cell and the relationship between the sarcoidosis and the PM(2.5) in the atmosphere.. Paraffin-embedded tissues of 50 cases of human sarcoidosis biopsy samples, 10 cases of non-sarcoidosis autopsy lung samples, 18 cases of lung tissues (with granulomatous lesions) of rats exposed to PM(2.5) by bronchial infusion, and the free PM(2.5) sample in the atmosphere were collected. The characteristics of tissues above mentioned were observed under the light microscopy, which stained by HE staining and Warthin-Starry silver staining. The characteristics of the PM(2.5) in the four groups were analyzed using confocal Raman microscopy. The component of the PM(2.5) in the sarcoidosis granuloma was analyzed using transmission electron microscope-energy dispersive X-ray detector (TEM-EDX), and the component of the PM(2.5) in the atmosphere was analyzed with X-ray fluorescence separately.. The PM(2.5) in the four groups have the similar Raman spectrum, they share the feature of carbonaceous composition, the element component of PM(2.5) in the human sarcoidosis was the same as PM(2.5) in the atmosphere.. The study provided the further evidence that the PM(2.5) in the sarcoidosis lesion was from PM(2.5) in the atmosphere, and it should be not excepted that sarcoidosis may be a sensitive individual reaction to the PM(2.5) inhaled from the atmosphere.

Topics: Adolescent; Adult; Aged; Air Pollutants; Aluminum; Animals; Carbon; Child; Female; Granuloma; Granuloma, Respiratory Tract; Humans; Lung; Male; Middle Aged; Particle Size; Particulate Matter; Rats; Sarcoidosis; Sarcoidosis, Pulmonary; Silicon; Skin Diseases; Spectrum Analysis, Raman; Young Adult

To investigate if there are dust particles in the cells of granulomas of sarcoidosis and analyze its composition and the possible correlation between the sarcoidosis and the composition of dust particles.. The samples of 50 patients with sarcoidosis and 6 patients with silicosis as control were collected by biopsy and/or autopsy sampling. The pathological varieties of the granulomas and the situation of the dust particles within the cells of granulomas were observed using hematoxylin and eosin staining, Warthin-Starry silver staining, immunohistochemistry staining as well as the transmission electron microscope, and the X-Ray spectrum chemical element analysis in the samples from these two kinds of diseases.. The dust particles containing silicon as the main chemical element were present in epithelioid cells and multinucleate giant cells in all the samples. The quantity of the particles deposited in sarcoidosis was less than that in the silicosis. Moreover, the dust cells were found in the granulomas and the visceral pleural lymphatic vessels in the pleura and the hilar pulmonary lymph nodes in sarcoidosis and silicosis. The pathological varieties of the granulomas in sarcoidosis and silicosis were similar.. There are less silicon dust particles in the cells of granulomas of sarcoidosis than in those of the silicotic nodules, which indicates that the silicon dust particles may be related to the sarcoidosis.

Topics: Adolescent; Adult; Aged; Child; Dust; Female; Granuloma; Humans; Male; Middle Aged; Sarcoidosis; Silicon; Silicosis

A 42-year-old man developed a papulonodular exanthema 10 years following an injury from a shell explosion. The differential diagnosis between sarcoid-like, foreign-body granulomas and Boeck's sarcoid was inconclusive by histology, but x-ray spectroanalytic examination revealed silicon particles within the epitheloid cell granulomas.

Topics: Adult; Diagnosis, Differential; Foreign Bodies; Granuloma; Humans; Male; Sarcoidosis; Silicon

Topics: Dermatitis, Occupational; Foreign Bodies; Granuloma; Humans; Male; Silicon; Silicones

Topics: Adult; Collagen Diseases; Cytoplasm; Eyebrows; Female; Fluorescent Antibody Technique; Granuloma; Humans; Immune Sera; Immunoglobulin G; Lip; Male; Middle Aged; Silicon; Skin Diseases

Topics: Adult; Explosions; Granuloma; Humans; Male; Purpura; Silicon; Silicosis; Skin Diseases; Skin Neoplasms

Topics: Child; Female; Granuloma; Humans; Silicon; Skin Diseases; Surgery, Plastic; Wounds and Injuries

Topics: Animals; Breast; Breast Neoplasms; Carcinogens; Face; Granuloma; Haplorhini; Humans; Injections; Pathology; Plastics; Research; Silicon; Silicon Compounds; Skin Neoplasms; Surgery, Plastic; Toxicology

Topics: Czechoslovakia; Dust; Eye Manifestations; Granuloma; Iron; Rabbits; Research; Silicon; Silicosis

Topics: Disease; Face; Granuloma; Granuloma, Foreign-Body; Humans; Medical Records; Silicon; Silicon Dioxide; Skin; Skin Neoplasms

Topics: Granuloma; Granuloma, Foreign-Body; Humans; Silicon; Skin; Skin Diseases

Topics: Animals; Anterior Chamber; Eye Diseases; Granuloma; Rabbits; Salicylates; Silicon; Silicon Dioxide

Topics: Fluorides; Granuloma; Hernia, Inguinal; Humans; Silicon

Topics: Granuloma; Granuloma, Foreign-Body; Humans; Silicon; Skin Neoplasms

Topics: Granuloma; Granuloma, Foreign-Body; Humans; Silicon; Silicon Dioxide; Skin; Skin Diseases