sildenafil-citrate and Amnesia--Transient-Global

A 69 years old male with erectile dysfunction lasting 2 years, took 50 mg of sildenafil for having sex with his wife at about 6 o'clock in the morning. One hour later his wife detected that he had an anterograde memory impairment: this was interpreted as a confusional state. The neurological examination suggested a transient global amnesia (TGA). EEG and cerebral magnetic resonance imaging were non-informative and memory deficits resolved within 24 h. Therefore, a TGA was diagnosed. Since no other trigger was detectable, sildenafil was deemed responsible for its occurrence.

Topics: Aged; Amnesia, Transient Global; Erectile Dysfunction; Humans; Male; Sildenafil Citrate; Vasodilator Agents

Topics: Amnesia, Transient Global; Cerebral Veins; Coitus; Hippocampus; Humans; Male; Middle Aged; Neuroimaging; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfonamides; Sympathetic Nervous System; Vasodilator Agents; Venous Pressure

Topics: Amnesia, Transient Global; Coitus; Cortical Spreading Depression; Humans; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilation

Topics: Amnesia, Transient Global; Contraindications; Humans; Male; Middle Aged; Migraine Disorders; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents