Page last updated: 2024-11-04

sibutramine and Polycystic Ovary Syndrome

sibutramine has been researched along with Polycystic Ovary Syndrome in 12 studies

sibutramine: serotonin and norepinephrine transporter inhibitor; Meridia is tradename for sibutramine hydrochloride

Polycystic Ovary Syndrome: A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.

Research Excerpts

ExcerptRelevanceReference
"Body weight reduction was greater in the sibutramine group."9.16Sibutramine administration decreases serum anti-Müllerian hormone (AMH) levels in women with polycystic ovary syndrome. ( Armeni, AK; Georgopoulos, NA; Katsikis, I; Panidis, D; Papadakis, E; Roupas, ND; Vosnakis, C, 2012)
"To examine the efficacy of sibutramine together with brief lifestyle modification for weight reduction in obese women with polycystic ovary syndrome (PCOS)."9.13Effect of sibutramine on weight reduction in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. ( Bixo, M; Björn, I; Eliasson, M; Johnson, O; Larsson, A; Lindholm, Å; Poromaa, IS; Wölner-Hanssen, P, 2008)
"Body weight reduced in both groups but the reduction was greater with sibutramine (-15."9.13Effect of hypocaloric diet plus sibutramine treatment on hormonal and metabolic features in overweight and obese women with polycystic ovary syndrome: a randomized, 24-week study. ( Diamanti-Kandarakis, E; Florakis, D; Georgopoulos, N; Karkanaki, A; Katsikis, I; Nassis, GP; Panidis, D, 2008)
"To evaluate the effectiveness of sibutramine therapy alone and in combination with ethinyl estradiol-cyproterone acetate (EE-CPA) on the clinical and metabolic parameters of obese women with polycystic ovary syndrome (PCOS)."9.10Sibutramine has a positive effect on clinical and metabolic parameters in obese patients with polycystic ovary syndrome. ( Harma, M; Kilic, F; Nazligul, Y; Sabuncu, T, 2003)
" The aim of the study was to assess serum vaspin levels in PCOS and the effects on vaspin levels of metformin or of weight loss."7.77The effect of weight loss and treatment with metformin on serum vaspin levels in women with polycystic ovary syndrome. ( Delkos, D; Dinas, K; Kalaitzakis, E; Kandaraki, EA; Katsikis, I; Koiou, E; Panidis, D; Tziomalos, K, 2011)
"Obesity is considered important factor contributing development of PCOS."5.32[Sibutramine administration in polycystic ovary syndrome treatment]. ( Banaś, M; Jochemczyk-Banek, U; Olszanecka-Glinianowicz, M; Zahorska-Markiewicz, B; Zurakowski, A, 2004)
" We assessed serum lipocalin-2 levels in polycystic ovary syndrome (PCOS) and the effects of weight loss or metformin on these levels."5.16Weight loss significantly reduces serum lipocalin-2 levels in overweight and obese women with polycystic ovary syndrome. ( Delkos, D; Kalaitzakis, E; Kandaraki, EA; Katsikis, I; Koiou, E; Panidis, D; Tziomalos, K; Vosnakis, C, 2012)
"Body weight reduction was greater in the sibutramine group."5.16Sibutramine administration decreases serum anti-Müllerian hormone (AMH) levels in women with polycystic ovary syndrome. ( Armeni, AK; Georgopoulos, NA; Katsikis, I; Panidis, D; Papadakis, E; Roupas, ND; Vosnakis, C, 2012)
"To examine the efficacy of sibutramine together with brief lifestyle modification for weight reduction in obese women with polycystic ovary syndrome (PCOS)."5.13Effect of sibutramine on weight reduction in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. ( Bixo, M; Björn, I; Eliasson, M; Johnson, O; Larsson, A; Lindholm, Å; Poromaa, IS; Wölner-Hanssen, P, 2008)
"Body weight reduced in both groups but the reduction was greater with sibutramine (-15."5.13Effect of hypocaloric diet plus sibutramine treatment on hormonal and metabolic features in overweight and obese women with polycystic ovary syndrome: a randomized, 24-week study. ( Diamanti-Kandarakis, E; Florakis, D; Georgopoulos, N; Karkanaki, A; Katsikis, I; Nassis, GP; Panidis, D, 2008)
"Aim of this study was to compare the effects of metformin and a body weight reduction regimen using sibutramine on insulinemia, insulin sensitivity, and ovarian function in women with anovulatory cycles or infertility."5.11Metformin versus sibutramine in the treatment of hyperinsulinemia in chronically anovulating women. ( Dravecka, I; Kraus, V; Lazurova, I; Petrovicova, J, 2004)
"To evaluate the effectiveness of sibutramine therapy alone and in combination with ethinyl estradiol-cyproterone acetate (EE-CPA) on the clinical and metabolic parameters of obese women with polycystic ovary syndrome (PCOS)."5.10Sibutramine has a positive effect on clinical and metabolic parameters in obese patients with polycystic ovary syndrome. ( Harma, M; Kilic, F; Nazligul, Y; Sabuncu, T, 2003)
" The aim of the study was to assess serum vaspin levels in PCOS and the effects on vaspin levels of metformin or of weight loss."3.77The effect of weight loss and treatment with metformin on serum vaspin levels in women with polycystic ovary syndrome. ( Delkos, D; Dinas, K; Kalaitzakis, E; Kandaraki, EA; Katsikis, I; Koiou, E; Panidis, D; Tziomalos, K, 2011)
"Obesity is considered important factor contributing development of PCOS."1.32[Sibutramine administration in polycystic ovary syndrome treatment]. ( Banaś, M; Jochemczyk-Banek, U; Olszanecka-Glinianowicz, M; Zahorska-Markiewicz, B; Zurakowski, A, 2004)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (66.67)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhuang, J1
Wang, X1
Xu, L1
Wu, T1
Kang, D1
Georgopoulos, NA2
Katsikis, I5
Florakis, D2
Panidis, D5
Kandarakis, ED1
Koiou, E2
Tziomalos, K2
Dinas, K1
Kalaitzakis, E2
Delkos, D2
Kandaraki, EA2
Vosnakis, C2
Armeni, AK1
Papadakis, E1
Roupas, ND1
Sabuncu, T1
Harma, M2
Nazligul, Y1
Kilic, F1
Olszanecka-Glinianowicz, M1
Zahorska-Markiewicz, B1
Jochemczyk-Banek, U1
Banaś, M1
Zurakowski, A1
Lazurova, I1
Dravecka, I1
Kraus, V1
Petrovicova, J1
Karabacak, IY1
Karabacak, O1
Törüner, FB1
Akdemir, O1
Arslan, M1
Lindholm, Å1
Bixo, M1
Björn, I1
Wölner-Hanssen, P1
Eliasson, M1
Larsson, A1
Johnson, O1
Poromaa, IS1
Diamanti-Kandarakis, E1
Nassis, GP1
Karkanaki, A1
Georgopoulos, N1
Aylwin, S1
Al-Zaman, Y1

Reviews

2 reviews available for sibutramine and Polycystic Ovary Syndrome

ArticleYear
Antidepressants for polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2013, May-31, Issue:5

    Topics: Antidepressive Agents; Cyclobutanes; Depression; Female; Fluoxetine; Humans; Polycystic Ovary Syndro

2013
Emerging concepts in the medical and surgical treatment of obesity.
    Frontiers of hormone research, 2008, Volume: 36

    Topics: Adipose Tissue; Amyloid; Anticonvulsants; Antidepressive Agents; Anxiety; Appetite Regulation; Baria

2008

Trials

7 trials available for sibutramine and Polycystic Ovary Syndrome

ArticleYear
Weight loss significantly reduces serum lipocalin-2 levels in overweight and obese women with polycystic ovary syndrome.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2012, Volume: 28, Issue:1

    Topics: Acute-Phase Proteins; Adolescent; Adult; Anti-Obesity Agents; Caloric Restriction; Combined Modality

2012
Sibutramine administration decreases serum anti-Müllerian hormone (AMH) levels in women with polycystic ovary syndrome.
    European journal of obstetrics, gynecology, and reproductive biology, 2012, Volume: 163, Issue:2

    Topics: Adult; Anthropometry; Anti-Mullerian Hormone; Appetite Depressants; Caloric Restriction; Cyclobutane

2012
Sibutramine has a positive effect on clinical and metabolic parameters in obese patients with polycystic ovary syndrome.
    Fertility and sterility, 2003, Volume: 80, Issue:5

    Topics: Adult; Androgen Antagonists; Appetite Depressants; Blood Pressure; Body Constitution; Body Weight; C

2003
Metformin versus sibutramine in the treatment of hyperinsulinemia in chronically anovulating women.
    Bratislavske lekarske listy, 2004, Volume: 105, Issue:5-6

    Topics: Adult; Anovulation; Appetite Depressants; Body Mass Index; Chronic Disease; Cyclobutanes; Diet, Redu

2004
Treatment effect of sibutramine compared to fluoxetine on leptin levels in polycystic ovary disease.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2004, Volume: 19, Issue:4

    Topics: Adult; Appetite Depressants; Body Mass Index; Cyclobutanes; Female; Fluoxetine; Follicle Stimulating

2004
Effect of sibutramine on weight reduction in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial.
    Fertility and sterility, 2008, Volume: 89, Issue:5

    Topics: Adolescent; Adult; Appetite Depressants; Body Weight; Cardiovascular Diseases; Cyclobutanes; Double-

2008
Effect of hypocaloric diet plus sibutramine treatment on hormonal and metabolic features in overweight and obese women with polycystic ovary syndrome: a randomized, 24-week study.
    International journal of obesity (2005), 2008, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Androgens; Anthropometry; Appetite Depressants; Blood Glucose; Body Fat Distribut

2008

Other Studies

3 other studies available for sibutramine and Polycystic Ovary Syndrome

ArticleYear
Effect of sibutramine on weight reduction and insulin resistance in women with polycystic ovary syndrome.
    Fertility and sterility, 2009, Volume: 91, Issue:6

    Topics: Appetite Depressants; Body Mass Index; Body Weight; Cyclobutanes; Female; Humans; Insulin Resistance

2009
The effect of weight loss and treatment with metformin on serum vaspin levels in women with polycystic ovary syndrome.
    Endocrine journal, 2011, Volume: 58, Issue:4

    Topics: Adolescent; Adult; Body Mass Index; Cyclobutanes; Diet, Reducing; Female; Humans; Lactones; Metformi

2011
[Sibutramine administration in polycystic ovary syndrome treatment].
    Ginekologia polska, 2004, Volume: 75, Issue:6

    Topics: Adolescent; Appetite Depressants; Cyclobutanes; Diet, Fat-Restricted; Female; Humans; Obesity; Polyc

2004