sibutramine has been researched along with Long QT Syndrome in 2 studies
sibutramine: serotonin and norepinephrine transporter inhibitor; Meridia is tradename for sibutramine hydrochloride
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A previously well 51-year-old woman with obesity but no other relevant past medical history or cardiac risk factors was prescribed sibutramine (initial dose 10 mg daily, increased to 15 mg daily after 10 wk)." | 3.74 | Sibutramine-associated QT interval prolongation and cardiac arrest. ( Corallo, CE; Ernest, D; Gershenzon, A; Nagappan, R, 2008) |
| "Other IMMP case reports suggesting arrhythmias associated with sibutramine were assessed and further reports were obtained from the World Health Organisation (WHO) adverse drug reactions database." | 1.33 | QT interval prolongation associated with sibutramine treatment. ( Clark, DW; Harrison-Woolrych, M; Hill, GR; Rees, MI; Skinner, JR, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ernest, D | 1 |
| Gershenzon, A | 1 |
| Corallo, CE | 1 |
| Nagappan, R | 1 |
| Harrison-Woolrych, M | 1 |
| Clark, DW | 1 |
| Hill, GR | 1 |
| Rees, MI | 1 |
| Skinner, JR | 1 |
2 other studies available for sibutramine and Long QT Syndrome
| Article | Year |
|---|---|
Sibutramine-associated QT interval prolongation and cardiac arrest.
Topics: Appetite Depressants; Cyclobutanes; Defibrillators, Implantable; Drug Monitoring; Electrocardiograph | 2008 |
QT interval prolongation associated with sibutramine treatment.
Topics: Adult; Amino Acid Substitution; Appetite Depressants; Arrhythmias, Cardiac; Cyclobutanes; Electrocar | 2006 |