sibutramine has been researched along with Coronary Disease in 7 studies
sibutramine: serotonin and norepinephrine transporter inhibitor; Meridia is tradename for sibutramine hydrochloride
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Sibutramine, a serotonin and norepinephrine transporter blocker, is widely used as an adjunctive obesity treatment, but its impact on endothelial function in obese patients with CAD has not yet been investigated." | 9.12 | Short-term sibutramine therapy is associated with weight loss and improved endothelial function in obese patients with coronary artery disease. ( Beigel, R; Feinberg, MS; Freimark, D; Matetzky, S; Shechter, M, 2006) |
| " Sibutramine, a serotonin and norepinephrine transporter blocker, is widely used as an adjunctive obesity treatment, but its impact on endothelial function in obese patients with CAD has not yet been investigated." | 5.12 | Short-term sibutramine therapy is associated with weight loss and improved endothelial function in obese patients with coronary artery disease. ( Beigel, R; Feinberg, MS; Freimark, D; Matetzky, S; Shechter, M, 2006) |
| "Obesity has long been known to accompany a host of chronic diseases, e." | 2.41 | Treating obesity: a new target for prevention of coronary heart disease. ( Aronne, LJ, 2001) |
| "Overweight and obesity have not only a significant psychological impact but also result in an increased risk for development of numerous chronic and sometimes fatal diseases." | 2.41 | Epidemiology, morbidity, and treatment of overweight and obesity. ( Aronne, LJ, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blackburn, GL | 1 |
| Waltman, BA | 1 |
| Shechter, M | 1 |
| Beigel, R | 1 |
| Freimark, D | 1 |
| Matetzky, S | 1 |
| Feinberg, MS | 1 |
| Brennan, A | 2 |
| Ara, R | 2 |
| Sterz, R | 1 |
| Matiba, B | 1 |
| Bergemann, R | 1 |
| McLaughlin, T | 1 |
| Abbasi, F | 1 |
| Kim, HS | 1 |
| Lamendola, C | 1 |
| Schaaf, P | 1 |
| Reaven, G | 1 |
| Aronne, LJ | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Progressive Weight Loss and Metabolic Health[NCT01299519] | 59 participants (Actual) | Interventional | 2011-02-28 | Completed | |||
| Evaluation of the Effectiveness of Cryotherapy in Slimming of the Abdomen and Saddlebags[NCT04287153] | 30 participants (Actual) | Interventional | 2017-09-17 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for sibutramine and Coronary Disease
| Article | Year |
|---|---|
Pharmacotherapy to reduce visceral fat.
Topics: Anti-Obesity Agents; Coronary Disease; Cyclobutanes; Exercise; Feeding Behavior; Humans; Intra-Abdom | 2005 |
Treating obesity: a new target for prevention of coronary heart disease.
Topics: Anti-Obesity Agents; Coronary Disease; Cyclobutanes; Humans; Lactones; Obesity; Orlistat; Randomized | 2001 |
Epidemiology, morbidity, and treatment of overweight and obesity.
Topics: Adult; Aged; Antipsychotic Agents; Appetite Depressants; Body Height; Body Mass Index; Body Weight; | 2001 |
2 trials available for sibutramine and Coronary Disease
| Article | Year |
|---|---|
Short-term sibutramine therapy is associated with weight loss and improved endothelial function in obese patients with coronary artery disease.
Topics: Aged; Appetite Depressants; Brachial Artery; Coronary Disease; Cyclobutanes; Endothelium, Vascular; | 2006 |
The cost-effectiveness of sibutramine in non-diabetic obese patients: evidence from four Western countries.
Topics: Adult; Age Distribution; Aged; Appetite Depressants; Cohort Studies; Coronary Disease; Cost-Benefit | 2007 |
2 other studies available for sibutramine and Coronary Disease
| Article | Year |
|---|---|
Assessment of clinical and economic benefits of weight management with sibutramine in general practice in Germany.
Topics: Adult; Appetite Depressants; Coronary Disease; Cost-Benefit Analysis; Cyclobutanes; Diabetes Mellitu | 2006 |
Relationship between insulin resistance, weight loss, and coronary heart disease risk in healthy, obese women.
Topics: Appetite Depressants; Body Mass Index; Coronary Disease; Cyclobutanes; Energy Intake; Fasting; Femal | 2001 |