Page last updated: 2024-11-04

sibutramine and Bipolar Disorder

sibutramine has been researched along with Bipolar Disorder in 8 studies

sibutramine: serotonin and norepinephrine transporter inhibitor; Meridia is tradename for sibutramine hydrochloride

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"In this 24-week, open-label, flexible-dose, comparison trial, 46 outpatients with bipolar disorders who had a body mass index (BMI) > or =30 kg/m(2), or > or =27 kg/m(2) with obesity-related comorbidities, and psychotropic-associated weight gain were randomly assigned to receive sibutramine (n = 18; 5-15 mg/day) or topiramate (n = 28; 25-600 mg/day)."9.12A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disorders. ( Altshuler, LL; Black, D; Denicoff, KD; Frye, MA; Hellemann, G; Keck, PE; Kupka, R; Leverich, GS; McElroy, SL; Mintz, J; Nolen, W; Post, RM; Suppes, T, 2007)
"Minimal recommended dose of sibutramine induced manic episode that was the first manifestation of bipolar disorder."7.78Sibutramine-induced mania as the first manifestation of bipolar disorder. ( Simonienko, K; Szajda, SD; Szulc, A; Waszkiewicz, N; Zalewska, A; Zalewska-Szajda, B; Zwierz, K; Ładny, JR, 2012)
"In this 24-week, open-label, flexible-dose, comparison trial, 46 outpatients with bipolar disorders who had a body mass index (BMI) > or =30 kg/m(2), or > or =27 kg/m(2) with obesity-related comorbidities, and psychotropic-associated weight gain were randomly assigned to receive sibutramine (n = 18; 5-15 mg/day) or topiramate (n = 28; 25-600 mg/day)."5.12A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disorders. ( Altshuler, LL; Black, D; Denicoff, KD; Frye, MA; Hellemann, G; Keck, PE; Kupka, R; Leverich, GS; McElroy, SL; Mintz, J; Nolen, W; Post, RM; Suppes, T, 2007)
"Minimal recommended dose of sibutramine induced manic episode that was the first manifestation of bipolar disorder."3.78Sibutramine-induced mania as the first manifestation of bipolar disorder. ( Simonienko, K; Szajda, SD; Szulc, A; Waszkiewicz, N; Zalewska, A; Zalewska-Szajda, B; Zwierz, K; Ładny, JR, 2012)
" Included were 158 patients with schizophrenia or bipolar disorder and a body mass index (BMI) > or = 25 kg/m2 who had received olanzapine treatment in combination with nizatidine (n = 68), sibutramine (n = 42), or amantadine (n = 48)."3.75Predictors and correlates for weight changes in patients co-treated with olanzapine and weight mitigating agents; a post-hoc analysis. ( Heinloth, AN; Hoffmann, VP; Kinon, BJ; Lipkovich, I; McGregor, HS; Stauffer, VL, 2009)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (75.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rocha, FF1
Bamberg, TO1
Pinto, FC1
Gomes, LM1
Silveira, S1
Rihmer, Z1
Purebl, G1
Faludi, G1
Halmy, L1
Stauffer, VL1
Lipkovich, I1
Hoffmann, VP1
Heinloth, AN1
McGregor, HS1
Kinon, BJ1
Binbay, T1
Waszkiewicz, N1
Zalewska-Szajda, B1
Szajda, SD1
Simonienko, K1
Zalewska, A1
Szulc, A1
Ładny, JR1
Zwierz, K1
Cordeiro, Q1
Vallada, H1
McElroy, SL1
Frye, MA1
Altshuler, LL1
Suppes, T1
Hellemann, G1
Black, D1
Mintz, J1
Kupka, R1
Nolen, W1
Leverich, GS1
Denicoff, KD1
Post, RM1
Keck, PE1
Benazzi, F1

Reviews

1 review available for sibutramine and Bipolar Disorder

ArticleYear
[Association of obesity and depression].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2008, Volume: 10, Issue:4

    Topics: Anti-Obesity Agents; Antidepressive Agents; Appetite Depressants; Appetite Regulation; Bipolar Disor

2008

Trials

1 trial available for sibutramine and Bipolar Disorder

ArticleYear
A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disorders.
    Bipolar disorders, 2007, Volume: 9, Issue:4

    Topics: Adult; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Appetite Depressants; Bipolar D

2007

Other Studies

6 other studies available for sibutramine and Bipolar Disorder

ArticleYear
Hypomanic episode secondary to sibutramine in a patient with type-I bipolar disorder.
    Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2008, Volume: 30, Issue:4

    Topics: Adult; Appetite Depressants; Bipolar Disorder; Cyclobutanes; Female; Humans; Obesity

2008
Predictors and correlates for weight changes in patients co-treated with olanzapine and weight mitigating agents; a post-hoc analysis.
    BMC psychiatry, 2009, Mar-28, Volume: 9

    Topics: Adult; Amantadine; Appetite; Benzodiazepines; Bipolar Disorder; Cognition Disorders; Cyclobutanes; D

2009
[First-episode mania with psychotic features induced by over-the-counter diet aids containing sibutramine].
    Turk psikiyatri dergisi = Turkish journal of psychiatry, 2010,Winter, Volume: 21, Issue:4

    Topics: Appetite Depressants; Bipolar Disorder; Cyclobutanes; Humans; Hypnotics and Sedatives; Lorazepam; No

2010
Sibutramine-induced mania as the first manifestation of bipolar disorder.
    BMC psychiatry, 2012, May-18, Volume: 12

    Topics: Antidepressive Agents; Bipolar Disorder; Cyclobutanes; Depressive Disorder; Female; Humans; Young Ad

2012
Sibutramine-induced mania episode in a bipolar patient.
    The international journal of neuropsychopharmacology, 2002, Volume: 5, Issue:3

    Topics: Adolescent; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cyclobutanes; Humans; Male; V

2002
Organic hypomania secondary to sibutramine-citalopram interaction.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:2

    Topics: Adult; Appetite Depressants; Bipolar Disorder; Citalopram; Cyclobutanes; Depressive Disorder; Drug I

2002