Page last updated: 2024-11-04

sibutramine and Arrhythmia

sibutramine has been researched along with Arrhythmia in 6 studies

sibutramine: serotonin and norepinephrine transporter inhibitor; Meridia is tradename for sibutramine hydrochloride

Research Excerpts

ExcerptRelevanceReference
"This study has shown an elevation in QTd, which may lead to cardiac arrhythmias, after sibutramine treatment."7.76Elevation of QT dispersion after obesity drug sibutramine. ( Algul, B; Ata, N; Dal, K; Demirel, G; Deveci, OS; Ertugrul, DT; Kucukazman, M; Tutal, E; Yalcin, AA; Yavuz, B; Yilmaz, H, 2010)
"Addition of low-dose metoprolol to sibutramine therapy increased patient compliance to the treatment, and decreased the frequency and severity of side effects including hypertension and palpitations, without decreasing the drug efficacy or causing significant deleterious changes in metabolic parameters."5.11Effect of low-dose metoprolol in combination with sibutramine therapy in normotensive obese patients: a randomized controlled study. ( Baykan, M; Durmus, I; Erem, C; Ersoz, HO; Hacihasanoglu, A; Telatar, M; Ukinc, K, 2004)
"Sibutramine, a serotonin and norepinephrine transporter blocker, is a common adjunctive obesity treatment."5.11Paradoxical effect of sibutramine on autonomic cardiovascular regulation in obese hypertensive patients--sibutramine and blood pressure. ( Birkenfeld, AL; Jordan, J; Luft, FC; Pischon, T; Schroeder, C; Sharma, AM; Tank, J, 2005)
"This study has shown an elevation in QTd, which may lead to cardiac arrhythmias, after sibutramine treatment."3.76Elevation of QT dispersion after obesity drug sibutramine. ( Algul, B; Ata, N; Dal, K; Demirel, G; Deveci, OS; Ertugrul, DT; Kucukazman, M; Tutal, E; Yalcin, AA; Yavuz, B; Yilmaz, H, 2010)
"Other IMMP case reports suggesting arrhythmias associated with sibutramine were assessed and further reports were obtained from the World Health Organisation (WHO) adverse drug reactions database."1.33QT interval prolongation associated with sibutramine treatment. ( Clark, DW; Harrison-Woolrych, M; Hill, GR; Rees, MI; Skinner, JR, 2006)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yalcin, AA1
Yavuz, B1
Ertugrul, DT1
Algul, B1
Yilmaz, H1
Deveci, OS1
Kucukazman, M1
Ata, N1
Demirel, G1
Dal, K1
Tutal, E1
Ersoz, HO1
Ukinc, K1
Baykan, M1
Erem, C1
Durmus, I1
Hacihasanoglu, A1
Telatar, M1
Birkenfeld, AL1
Schroeder, C1
Pischon, T1
Tank, J1
Luft, FC1
Sharma, AM1
Jordan, J1
Harrison-Woolrych, M1
Clark, DW1
Hill, GR1
Rees, MI1
Skinner, JR1
Wooltorton, E1
Deitel, M1

Trials

2 trials available for sibutramine and Arrhythmia

ArticleYear
Effect of low-dose metoprolol in combination with sibutramine therapy in normotensive obese patients: a randomized controlled study.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2004, Volume: 28, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Anthropometry; Appetite Depressants; Arrhythmias, Cardiac; Cyclo

2004
Paradoxical effect of sibutramine on autonomic cardiovascular regulation in obese hypertensive patients--sibutramine and blood pressure.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2005, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Aged; Appetite Depressants; Arrhythmias, Cardiac; Autonomic Nervous System; Baror

2005

Other Studies

4 other studies available for sibutramine and Arrhythmia

ArticleYear
Elevation of QT dispersion after obesity drug sibutramine.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:11

    Topics: Adult; Anti-Obesity Agents; Arrhythmias, Cardiac; Caloric Restriction; Combined Modality Therapy; Cy

2010
QT interval prolongation associated with sibutramine treatment.
    British journal of clinical pharmacology, 2006, Volume: 61, Issue:4

    Topics: Adult; Amino Acid Substitution; Appetite Depressants; Arrhythmias, Cardiac; Cyclobutanes; Electrocar

2006
Obesity drug sibutramine (Meridia): hypertension and cardiac arrhythmias.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2002, May-14, Volume: 166, Issue:10

    Topics: Appetite Depressants; Arrhythmias, Cardiac; Cyclobutanes; Humans; Hypertension; Obesity

2002
Sibutramine warning: hypertension and cardiac arrhythmias reported.
    Obesity surgery, 2002, Volume: 12, Issue:3

    Topics: Appetite Depressants; Arrhythmias, Cardiac; Contraindications; Cyclobutanes; Humans; Hypertension

2002