Page last updated: 2024-09-05

sibenadet and Airflow Obstruction, Chronic

sibenadet has been researched along with Airflow Obstruction, Chronic in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (90.91)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alcaraz, L; Bailey, A; Cadogan, E; Connolly, S; Dainty, I; Jewell, R; Jordan, S; Kindon, N; Lawson, M; Lister, A; Mullen, A; Nicholls, D; Paine, S; Pairaudeau, G; Stocks, MJ; Thorne, P; Young, A1
Rennard, SI1
Dougall, IG; Ince, F; Jackson, DM; Young, A1
Deamer, L; Ind, PW; Laitinen, L; Laursen, L; Nystrom, P; Wenzel, S; Wouters, E1
Hepburn, T; Laursen, LC; Lindqvist, A; Lloyd, J; Perrett, J; Rocchiccioli, K; Sanders, N1
Byrne, N; Celli, B; Goldman, M; Halpin, D; Hepburn, R; Keating, ET1
Alderfer, V; Goldman, M; Hiller, FC1
Jones, MK; Lordan, N; McMillan, C; O'Brien, JA; Ward, AJ1
Jones, MK; Leidy, NK; Lloyd, J; Rocchiccioli, K; Schmier, JK1
Calverley, P; Casty, F; Goldman, M; Keating, ET1
Agnew, JE; Dilworth, JP; Hasani, A; Lloyd, J; Toms, N1

Trials

7 trial(s) available for sibenadet and Airflow Obstruction, Chronic

ArticleYear
Early clinical investigation of Viozan (sibenadet HCl), a novel D2 dopamine receptor, beta2-adrenoceptor agonist for the treatment of chronic obstructive pulmonary disease symptoms.
    Respiratory medicine, 2003, Volume: 97 Suppl A

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Metered Dose Inhalers; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quality of Life; Receptors, Adrenergic, beta-2; Receptors, Dopamine D2; Thiazoles; Treatment Outcome; Vital Capacity

2003
The role of the novel D2/beta2-agonist, Viozan (sibenadet HCl), in the treatment of symptoms of chronic obstructive pulmonary disease: results of a large-scale clinical investigation.
    Respiratory medicine, 2003, Volume: 97 Suppl A

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Metered Dose Inhalers; Middle Aged; Patient Satisfaction; Peak Expiratory Flow Rate; Pulmonary Disease, Chronic Obstructive; Quality of Life; Receptors, Adrenergic, beta-2; Receptors, Dopamine D2; Thiazoles; Treatment Outcome

2003
Symptoms are an important outcome in chronic obstructive pulmonary disease clinical trials: results of a 3-month comparative study using the Breathlessness, Cough and Sputum Scale (BCSS).
    Respiratory medicine, 2003, Volume: 97 Suppl A

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Cough; Double-Blind Method; Dyspnea; Female; Forced Expiratory Volume; Humans; Male; Metered Dose Inhalers; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quality of Life; Receptors, Adrenergic, beta-2; Receptors, Dopamine D2; Sputum; Survival Analysis; Thiazoles; Treatment Outcome; Vital Capacity

2003
Long-term use of Viozan (sibenadet HCl) in patients with chronic obstructive pulmonary disease: results of a 1-year study.
    Respiratory medicine, 2003, Volume: 97 Suppl A

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Long-Term Care; Male; Metered Dose Inhalers; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quality of Life; Receptors, Adrenergic, beta-2; Receptors, Dopamine D2; Smoking; Thiazoles; Treatment Outcome

2003
Utilization of health care services by patients with chronic obstructive pulmonary disease.
    Respiratory medicine, 2003, Volume: 97 Suppl A

    Topics: Adrenergic beta-2 Receptor Agonists; Adult; Aged; Bronchodilator Agents; Double-Blind Method; Female; Health Services; Hospitalization; Humans; Male; Middle Aged; Patient Acceptance of Health Care; Pulmonary Disease, Chronic Obstructive; Receptors, Adrenergic, beta-2; Receptors, Dopamine D2; Thiazoles

2003
Evaluating symptoms in chronic obstructive pulmonary disease: validation of the Breathlessness, Cough and Sputum Scale.
    Respiratory medicine, 2003, Volume: 97 Suppl A

    Topics: Adrenergic beta-Antagonists; Aged; Bronchodilator Agents; Cough; Data Collection; Dopamine Antagonists; Dyspnea; Female; Health Status Indicators; Humans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Reproducibility of Results; Sensitivity and Specificity; Sputum; Thiazoles

2003
Mucociliary clearance in COPD can be increased by both a D2/beta2 and a standard beta2 agonists.
    Respiratory medicine, 2005, Volume: 99, Issue:2

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aged; Albuterol; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Mucociliary Clearance; Peak Expiratory Flow Rate; Pulmonary Disease, Chronic Obstructive; Quality of Life; Risk Factors; Smoking; Sputum; Thiazoles; Treatment Outcome; Vital Capacity

2005

Other Studies

4 other study(ies) available for sibenadet and Airflow Obstruction, Chronic

ArticleYear
From libraries to candidate: the discovery of new ultra long-acting dibasic β₂-adrenoceptor agonists.
    Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Asthma; Bronchodilator Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Cyclic AMP; Drug Design; Guinea Pigs; Humans; Inhibitory Concentration 50; Models, Chemical; Protein Binding; Pulmonary Disease, Chronic Obstructive; Thiazoles; Time Factors

2012
Introduction. The symposium that never occurred: pre-clinical and clinical development of sibenadet.
    Respiratory medicine, 2003, Volume: 97 Suppl A

    Topics: Adrenergic beta-Agonists; Bronchodilator Agents; Dopamine Antagonists; Humans; Pulmonary Disease, Chronic Obstructive; Thiazoles; Treatment Outcome

2003
Dual dopamine D2 receptor and beta2-adrenoceptor agonists for the treatment of chronic obstructive pulmonary disease: the pre-clinical rationale.
    Respiratory medicine, 2003, Volume: 97 Suppl A

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Drug Design; Humans; Models, Biological; Neurons, Afferent; Pulmonary Disease, Chronic Obstructive; Receptors, Dopamine D2; Thiazoles

2003
Conclusion. Lessons from the novel D2 dopamine receptor, beta2-adrenoceptor agonist, Viozan: chronic obstructive pulmonary disease and drug development implications.
    Respiratory medicine, 2003, Volume: 97 Suppl A

    Topics: Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Cough; Drug Design; Dyspnea; Forced Expiratory Volume; Humans; Pulmonary Disease, Chronic Obstructive; Receptors, Adrenergic, beta-2; Receptors, Dopamine D2; Research Design; Sputum; Thiazoles

2003