shu-9119 and Starvation

shu-9119 has been researched along with Starvation* in 1 studies

Other Studies

1 other study(ies) available for shu-9119 and Starvation

Article	Year
Melanocortin system and eating disorders. Annals of the New York Academy of Sciences, 2003, Volume: 994 The melanocortin (MC) system is involved in the regulation of energy balance and in the development of obesity. Here we briefly review why we became interested in investigating whether the MC system - more particularly, the increased activity of the MC system - is also involved in disorders of negative energy balance. We provide evidence that suppression of increased MC receptor activity by treatment with the inverse agonist agouti-related peptide (AgRP) (83-132) rescues rats exposed to an animal model known as activity-based anorexia. Furthermore, we found a polymorphism, Ala67Thr AgRP, that was observed more frequently in anorexia nervosa. Topics: Agouti-Related Protein; alpha-MSH; Animals; Behavior, Animal; Binding Sites; Feeding and Eating Disorders; Hypothalamo-Hypophyseal System; Intercellular Signaling Peptides and Proteins; Melanocyte-Stimulating Hormones; Peptides; Pituitary-Adrenal System; Polymorphism, Genetic; Pro-Opiomelanocortin; Proteins; Rats; Receptors, Corticotropin; Receptors, Melanocortin; Starvation	2003

Article

Year

Melanocortin system and eating disorders.

Annals of the New York Academy of Sciences, 2003, Volume: 994

The melanocortin (MC) system is involved in the regulation of energy balance and in the development of obesity. Here we briefly review why we became interested in investigating whether the MC system - more particularly, the increased activity of the MC system - is also involved in disorders of negative energy balance. We provide evidence that suppression of increased MC receptor activity by treatment with the inverse agonist agouti-related peptide (AgRP) (83-132) rescues rats exposed to an animal model known as activity-based anorexia. Furthermore, we found a polymorphism, Ala67Thr AgRP, that was observed more frequently in anorexia nervosa.

Topics: Agouti-Related Protein; alpha-MSH; Animals; Behavior, Animal; Binding Sites; Feeding and Eating Disorders; Hypothalamo-Hypophyseal System; Intercellular Signaling Peptides and Proteins; Melanocyte-Stimulating Hormones; Peptides; Pituitary-Adrenal System; Polymorphism, Genetic; Pro-Opiomelanocortin; Proteins; Rats; Receptors, Corticotropin; Receptors, Melanocortin; Starvation

2003