shu-508 and Anemia

shu-508 has been researched along with Anemia* in 1 studies

Other Studies

1 other study(ies) available for shu-508 and Anemia

ArticleYear
Erythrocytes, as well as microbubble contrast agents, are important factors in improving thermal and therapeutic effects of high-intensity focused ultrasound.
    Ultrasound in medicine & biology, 2005, Volume: 31, Issue:3

    Erythrocytes, as well as microbubble contrast agents, are important factors in improving thermal effect of high-intensity focused ultrasound (US), or HIFU, and increasing the coagulation volume produced by HIFU irradiation. In vitro experiments used human plasma with various concentrations of human erythrocytes in combination with or without Levovist. In vivo experiments used eight Japan white rabbits with three degrees of anemia. Using a 2.17-MHz transducer, HIFU was applied for 60 s, and the temperature rise and the volume of coagulation necrosis was evaluated. There was a significant correlation between the HIFU-induced temperature rise and hematocrit, with a correlation coefficient of 0.998 (p=0.0001). Although the temperature rise was smaller at low hematocrit, it was significantly increased by adding Levovist in the suspension (p<0.01). The mean volume of coagulation necrosis was significantly greater in the rabbits with higher hematocrits (p<0.01), and that in the moderate anemia group was significantly increased by using Levovist (p<0.01).

    Topics: Anemia; Animals; Blood Coagulation; Body Temperature; Contrast Media; Erythrocytes; Female; Hematocrit; Hot Temperature; Humans; Liver; Microbubbles; Necrosis; Polysaccharides; Rabbits; Ultrasonic Therapy

2005