shamixanthone and Breast-Neoplasms

shamixanthone has been researched along with Breast-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for shamixanthone and Breast-Neoplasms

Article	Year
Bioactive metabolites from a marine-derived strain of the fungus Emericella variecolor. Journal of natural products, 2002, Volume: 65, Issue:3 From a marine-derived strain of the fungus Emericella variecolor, varitriol (1), varioxirane (2), dihydroterrein (3), and varixanthone (4), besides the known mold metabolites ergosterol, terrein, shamixanthone, and tajixanthone hydrate, were identified. The chemical structures of 1-4 were established by means of spectroscopic techniques and some chemical transformations. In the NCI's 60-cell panel, varitriol (1) displayed increased potency toward selected renal, CNS, and breast cancer cell lines. Varixanthone (4) showed antimicrobial activity. Topics: Animals; Antibiotics, Antineoplastic; Antifungal Agents; Benzyl Alcohols; Breast Neoplasms; Caribbean Region; Central Nervous System Neoplasms; Colonic Neoplasms; Cyclopentanes; Drug Screening Assays, Antitumor; Ergosterol; Female; Fungi; Furans; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Kidney Neoplasms; Leukemia P388; Lung Neoplasms; Male; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Porifera; Prostatic Neoplasms; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured; Xanthenes; Xanthones	2002

Article

Year

Bioactive metabolites from a marine-derived strain of the fungus Emericella variecolor.

Journal of natural products, 2002, Volume: 65, Issue:3

From a marine-derived strain of the fungus Emericella variecolor, varitriol (1), varioxirane (2), dihydroterrein (3), and varixanthone (4), besides the known mold metabolites ergosterol, terrein, shamixanthone, and tajixanthone hydrate, were identified. The chemical structures of 1-4 were established by means of spectroscopic techniques and some chemical transformations. In the NCI's 60-cell panel, varitriol (1) displayed increased potency toward selected renal, CNS, and breast cancer cell lines. Varixanthone (4) showed antimicrobial activity.

Topics: Animals; Antibiotics, Antineoplastic; Antifungal Agents; Benzyl Alcohols; Breast Neoplasms; Caribbean Region; Central Nervous System Neoplasms; Colonic Neoplasms; Cyclopentanes; Drug Screening Assays, Antitumor; Ergosterol; Female; Fungi; Furans; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Kidney Neoplasms; Leukemia P388; Lung Neoplasms; Male; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Porifera; Prostatic Neoplasms; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured; Xanthenes; Xanthones

2002