Page last updated: 2024-08-24

sezolamide and Intraocular Pressure

sezolamide has been researched along with Intraocular Pressure in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (12.00)	18.7374
1990's	22 (88.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hunt, CA; Mallorga, PJ; Michelson, SR; Schwam, H; Shepard, KL; Smith, RL; Sondey, JM; Sugrue, MF	1
Brechue, WF; Maren, TH	3
Challa, P; Fanous, MM; Maren, TH	1
Camras, CB; Deasy, D; Framm, L; Lippa, EA; Lustgarten, J; Payne, JE; Podos, SM; Serle, JB	1
Gelatt, KN; Gum, GG; King, TC	1
Béchetoille, A; Gerling, J; Grehn, F; Greve, E; Gunning, F; Jaquet-Müller, F; Lippa, EA; Pfeiffer, N	1
Aasved, H; Airaksinen, PJ; Alm, A; Bertelsen, T; Calissendorff, B; Dithmer, O; Eriksson, LO; Gustad, L; Høvding, G; Lippa, EA	1
Bénichou, C; Bron, A; Clineschmidt, C; Flament, J; Gunning, F; Lesure, P; Lippa, EA; Panebianco, D; Royer, J; Sirbat, D	1
Deasy, DA; Epstein, DL; Higginbotham, EJ; Holder, DJ; Kass, MA; Lippa, EA; Schuman, JS; Shaw, B; Skuta, GL; Weinreb, RN	1
Brunner-Ferber, FL; Gerling, J; Grehn, F; Lippa, EA; Panebianco, D; Pfeiffer, N	1
Brunner-Ferber, F; Gerling, J; Grehn, F; Lippa, E; Pfeiffer, N	1
Camras, CB; Lippa, EA; Lustgarten, JS; Panebianco, DL; Podos, SM; Serle, JB	1
Garus, H; Grehn, F; Hennekes, R; Pfeiffer, N	1
Brunner-Ferber, FL; Garus, H; Grehn, F; Hennekes, R; Lippa, EA; Pfeiffer, N	1
Brunner-Ferber, F; Feicht, B; Hofmann, HM; Lippa, E; Merté, HJ; von Denffer, H	1
Bar-Ilan, A; Brechue, WF; Conroy, CW; Maren, TH	1
Podos, SM; Serle, JB; Surgrue, MF; Wang, RF	1
Bechetoille, A; Brunner-Ferber, F; Diestelhorst, M; Krieglstein, GK; Lippa, E	1
Baldwin, JJ; Christy, ME; Gautheron, P; Grove, J; Mallorga, P; Ponticello, GS; Schwam, H; Sugrue, MF; Viader, MP	1
Batenhorst, RL; Higginbotham, EJ; Kass, MA; Lippa, EA; Panebianco, DL; Wilensky, JT	1
Bron, AM; Brunner-Ferber, FL; Feicht, BI; Hofmann, HM; Lippa, EA; Panebianco, DL; Royer, JG; Von Denffer, HA	1
Kass, MA	1
Brunner-Ferber, FL; Hofmann, HM; Lippa, EA; von Denffer, HA	1

Trials

15 trial(s) available for sezolamide and Intraocular Pressure

Article	Year
Six week safety study of 2% MK-927 administered twice daily to ocular hypertensive volunteers. Journal of ocular pharmacology, 1992,Spring, Volume: 8, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Safety; Sulfonamides; Thiophenes; Timolol	1992
[Additive effect of timolol and the local carbonic anhydrase inhibitor MK-417 (sezolamide)]. Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1991, Volume: 88, Issue:6 Topics: Aged; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol	1991
Multiple-dose, dose-response relationship for the topical carbonic anhydrase inhibitor MK-927. Archives of ophthalmology (Chicago, Ill. : 1960), 1991, Volume: 109, Issue:1 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Analysis of Variance; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Placebos; Sulfonamides; Thiophenes	1991
Multiple-dose efficacy comparison of the two topical carbonic anhydrase inhibitors sezolamide and MK-927. Archives of ophthalmology (Chicago, Ill. : 1960), 1991, Volume: 109, Issue:1 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Stereoisomerism; Sulfonamides; Thiophenes	1991
MK-507 versus sezolamide. Comparative efficacy of two topically active carbonic anhydrase inhibitors. Ophthalmology, 1991, Volume: 98, Issue:3 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes	1991
Comparative tolerability of topical carbonic anhydrase inhibitor MK-927 and its S-enantiomer MK-417. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1991, Volume: 229, Issue:2 Topics: Administration, Topical; Adult; Carbonic Anhydrase Inhibitors; Cornea; Double-Blind Method; Drug Tolerance; Humans; Intraocular Pressure; Male; Pupil; Stereoisomerism; Sulfonamides; Thiophenes	1991
[Local carbonic anhydrase inhibitors MK-927 and Mk-417. Effect and tolerance]. Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1990, Volume: 87, Issue:6 Topics: Adult; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sulfonamides; Thiophenes	1990
MK-927, a topical carbonic anhydrase inhibitor. Dose response and reproducibility. Archives of ophthalmology (Chicago, Ill. : 1960), 1990, Volume: 108, Issue:6 Topics: Administration, Topical; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Time Factors	1990
[Decrease in intraocular pressure following administration of the local carbonic anhydrase inhibitor (MK-927)--comparison of the effect with pilocarpine]. Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1990, Volume: 87, Issue:2 Topics: Carbonic Anhydrase Inhibitors; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes	1990
A single dose of the topical carbonic anhydrase inhibitor MK-927 decreases IOP in patients. The British journal of ophthalmology, 1990, Volume: 74, Issue:7 Topics: Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes	1990
[A new topical carbonic anhydrase inhibitor (MK-927). Tolerance comparison with betaxolol in healthy probands]. Klinische Monatsblatter fur Augenheilkunde, 1990, Volume: 197, Issue:3 Topics: Administration, Topical; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Tolerance; Humans; Intraocular Pressure; Male; Sulfonamides; Thiophenes; Time Factors	1990
[Stereospecificity of lowering intraocular pressure using a locally administered carbonic anhydrase inhibitor]. Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1990, Volume: 87, Issue:2 Topics: Adult; Aged; Carbonic Anhydrase Inhibitors; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Racemases and Epimerases; Sulfonamides; Thiophenes	1990
MK-927: a topical carbonic anhydrase inhibitor. Dose response and duration of action. Archives of ophthalmology (Chicago, Ill. : 1960), 1990, Volume: 108, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Time Factors; Visual Acuity	1990
MK-927: a topically effective carbonic anhydrase inhibitor in patients. Archives of ophthalmology (Chicago, Ill. : 1960), 1989, Volume: 107, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Double-Blind Method; Eye Color; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Placebos; Random Allocation; Sulfonamides; Thiophenes	1989
Local tolerance and activity of MK-927, a novel topical carbonic anhydrase inhibitor. Archives of ophthalmology (Chicago, Ill. : 1960), 1988, Volume: 106, Issue:12 Topics: Adult; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Double-Blind Method; Eye; Humans; Hyperemia; Intraocular Pressure; Male; Ophthalmic Solutions; Placebos; Random Allocation; Sulfonamides; Thiophenes	1988

Other Studies

10 other study(ies) available for sezolamide and Intraocular Pressure

Article	Year
3-substituted thieno[2,3-b][1,4]thiazine-6-sulfonamides. A novel class of topically active carbonic anhydrase inhibitors. Journal of medicinal chemistry, 1994, Jan-21, Volume: 37, Issue:2 Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Humans; In Vitro Techniques; Intraocular Pressure; Models, Molecular; Rabbits; Solubility; Sulfonamides	1994
pH and drug ionization affects ocular pressure lowering of topical carbonic anhydrase inhibitors. Investigative ophthalmology & visual science, 1993, Volume: 34, Issue:8 Topics: Animals; Carbonic Anhydrase Inhibitors; Eye; Hydrogen-Ion Concentration; Imidazoles; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Osmolar Concentration; Rabbits; Solubility; Sulfonamides; Thiophenes	1993
A comparison between the effect of topical and systemic carbonic anhydrase inhibitors on aqueous humor secretion. Experimental eye research, 1993, Volume: 57, Issue:1 Topics: Administration, Topical; Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Ethoxzolamide; Injections, Intravenous; Intraocular Pressure; Male; Methazolamide; Rabbits; Sulfonamides; Thiophenes; Time Factors; Uvea	1993
Carbonic anhydrase inhibitory activity and ocular pharmacology of organic sulfamates. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2 Topics: Animals; Carbonic Anhydrase Inhibitors; Eye; Hydrogen-Ion Concentration; Imidazoles; Intraocular Pressure; Rabbits; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids; Thiophenes	1993
Comparison of intraocular pressure lowering by topical and systemic carbonic anhydrase inhibitors in the rabbit. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1999, Volume: 15, Issue:1 Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Hydrogen-Ion Concentration; Injections, Intravenous; Intraocular Pressure; Male; Methazolamide; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes; Tonometry, Ocular	1999
Evaluation of a topically administered carbonic anhydrase inhibitor (MK-927) in normotensive and glaucomatous beagles. American journal of veterinary research, 1991, Volume: 52, Issue:12 Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Female; Glaucoma; Intraocular Pressure; Male; Sulfonamides; Thiophenes	1991
Chemical and pharmacological properties of MK-927, a sulfonamide carbonic anhydrase inhibitor that lowers intraocular pressure by the topical route. Experimental eye research, 1990, Volume: 50, Issue:1 Topics: Administration, Topical; Animals; Anterior Eye Segment; Carbonic Anhydrase Inhibitors; Intraocular Pressure; Male; Rabbits; Sulfonamides; Thiophenes	1990
The effect of MK-927, a topical carbonic anhydrase inhibitor, on IOP in glaucomatous monkeys. Current eye research, 1990, Volume: 9, Issue:2 Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Female; Glaucoma; Intraocular Pressure; Macaca fascicularis; Sulfonamides; Thiophenes; Time Factors; Tonometry, Ocular	1990
MK-927: a topically active ocular hypotensive carbonic anhydrase inhibitor. Journal of ocular pharmacology, 1990,Spring, Volume: 6, Issue:1 Topics: Administration, Topical; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Chymotrypsin; Ciliary Body; Dose-Response Relationship, Drug; Female; Intraocular Pressure; Iris; Kinetics; Macaca fascicularis; Male; Ocular Hypertension; Rabbits; Sulfonamides; Thiophenes	1990
Topical carbonic anhydrase inhibitors. American journal of ophthalmology, 1989, Mar-15, Volume: 107, Issue:3 Topics: Administration, Topical; Benzothiazoles; Carbonic Anhydrase Inhibitors; Ethoxzolamide; Gels; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiazoles; Thiophenes	1989