Page last updated: 2024-11-04

sevoflurane and Stroke

sevoflurane has been researched along with Stroke in 8 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
" We examined the comparative effects of sevoflurane versus isoflurane on cerebrovascular CO2 reactivity in patients with previous stroke."9.13The comparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with previous stroke. ( Kadoi, Y; Saito, S; Takahashi, K, 2008)
"We observed an increase in mean middle cerebral artery blood flow velocity (V(mca)) after tourniquet deflation during orthopedic surgery under sevoflurane anesthesia in patients with diabetes mellitus or previous stroke."7.77Time course of changes in cerebral blood flow velocity after tourniquet deflation in patients with diabetes mellitus or previous stroke under sevoflurane anesthesia. ( Hinohara, H; Kadoi, Y; Kawauchi, C; Mizutani, A; Saito, S; Takahashi, K, 2011)
" We examined the comparative effects of sevoflurane versus isoflurane on cerebrovascular CO2 reactivity in patients with previous stroke."5.13The comparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with previous stroke. ( Kadoi, Y; Saito, S; Takahashi, K, 2008)
" It has demonstrated that sevoflurane has neuroprotective effects against ischemic stroke, but its effects on ischemia-induced formation of astrogliosis and glial scar are unknown."3.85Sevoflurane postconditioning attenuates reactive astrogliosis and glial scar formation after ischemia-reperfusion brain injury. ( Gao, X; Kent, TA; Li, W; Ni, Y; Qiao, SG; Wang, C; Xu, XX; Zhang, HL; Zhu, YM, 2017)
"We observed an increase in mean middle cerebral artery blood flow velocity (V(mca)) after tourniquet deflation during orthopedic surgery under sevoflurane anesthesia in patients with diabetes mellitus or previous stroke."3.77Time course of changes in cerebral blood flow velocity after tourniquet deflation in patients with diabetes mellitus or previous stroke under sevoflurane anesthesia. ( Hinohara, H; Kadoi, Y; Kawauchi, C; Mizutani, A; Saito, S; Takahashi, K, 2011)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's7 (87.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhu, YM1
Gao, X1
Ni, Y1
Li, W1
Kent, TA1
Qiao, SG1
Wang, C1
Xu, XX1
Zhang, HL1
Dong, P1
Zhao, J1
Zhang, Y2
Dong, J1
Zhang, L1
Li, D1
Li, L2
Zhang, X2
Yang, B1
Lei, W1
Purrucker, JC1
Renzland, J1
Uhlmann, L1
Bruckner, T1
Hacke, W1
Steiner, T1
Bösel, J1
Zhang, H1
Sun, Y1
Xu, S1
Zhao, P1
Liu, T1
Badenes, R1
Bilotta, F1
Hinohara, H1
Kadoi, Y2
Takahashi, K2
Saito, S2
Kawauchi, C1
Mizutani, A1
Gauberti, M1
Obiang, P1
Guedin, P1
Balossier, A1
Gakuba, C1
Diependaele, AS1
Chazalviel, L1
Vivien, D1
Young, AR1
Agin, V1
Orset, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Subanesthetic Sevoflurane for Treatment-Resistant Depression: A Proof-of-Concept Trial[NCT05008939]15 participants (Anticipated)Interventional2021-08-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for sevoflurane and Stroke

ArticleYear
The comparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with previous stroke.
    Journal of anesthesia, 2008, Volume: 22, Issue:2

    Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Flow Velocity; Carbon Di

2008

Other Studies

7 other studies available for sevoflurane and Stroke

ArticleYear
Sevoflurane postconditioning attenuates reactive astrogliosis and glial scar formation after ischemia-reperfusion brain injury.
    Neuroscience, 2017, 07-25, Volume: 356

    Topics: Animals; Astrocytes; Brain Ischemia; Cells, Cultured; Disease Models, Animal; Glial Fibrillary Acidi

2017
Aging causes exacerbated ischemic brain injury and failure of sevoflurane post-conditioning: role of B-cell lymphoma-2.
    Neuroscience, 2014, Sep-05, Volume: 275

    Topics: Age Factors; Aging; Animals; Apoptosis; Brain; Brain Ischemia; Disease Models, Animal; Ischemic Post

2014
Volatile sedation with sevoflurane in intensive care patients with acute stroke or subarachnoid haemorrhage using AnaConDa®: an observational study.
    British journal of anaesthesia, 2015, Volume: 114, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Anesthetics, Inhalation; Conscious Sedation;

2015
Sevoflurane prevents stroke-induced depressive and anxiety behaviors by promoting cannabinoid receptor subtype I-dependent interaction between β-arrestin 2 and extracellular signal-regulated kinases 1/2 in the rat hippocampus.
    Journal of neurochemistry, 2016, Volume: 137, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Anxiety; beta-Arrestin 2; Depression; Dose-Response Relationship,

2016
Inhaled sedation in acute brain injury patients.
    British journal of anaesthesia, 2016, Volume: 116, Issue:6

    Topics: Animals; Boidae; Brain Injuries; Critical Care; Humans; Sevoflurane; Stroke; Subarachnoid Hemorrhage

2016
Time course of changes in cerebral blood flow velocity after tourniquet deflation in patients with diabetes mellitus or previous stroke under sevoflurane anesthesia.
    Journal of anesthesia, 2011, Volume: 25, Issue:3

    Topics: Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Flow Velocity; Blood Gas Analysis; Bloo

2011
Thrombotic stroke in the anesthetized monkey (Macaca mulatta): characterization by MRI--a pilot study.
    Cerebrovascular diseases (Basel, Switzerland), 2012, Volume: 33, Issue:4

    Topics: Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Atracurium; Craniotomy; Dif

2012