Page last updated: 2024-11-04

sevoflurane and Pregnancy

sevoflurane has been researched along with Pregnancy in 168 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"This study explored the effects of sevoflurane exposure during different stages of pregnancy on the brain development of offspring."8.02Effects of sevoflurane exposure during different stages of pregnancy on the brain development of rat offspring. ( Cui, FH; Li, J; Li, KZ; Xie, YG; Zhao, XL, 2021)
"Sevoflurane is a widely used obstetric general anesthetic, but the neurotoxic effects of late-pregnancy exposure to one minimum alveolar concentration ([MAC], 2."7.96Effects of Sevoflurane Exposure During Late Pregnancy on Brain Development and Beneficial Effects of Enriched Environment on Offspring Cognition. ( Cui, J; Junzhang, P; Wang, H; Wang, J; Yu, Z, 2020)
"To compare the effects of sevoflurane or propofol combined with remifentanil anesthesia on the clinical efficacy and stress response of pregnancy-induced hypertension (PIHS) in cesarean section."7.88Effects of sevoflurane or propofol combined with remifentanil anesthesia on clinical efficacy and stress response in pregnant women with pregnancy-induced hypertension. ( Guan, Y; Ren, LQ; Sun, XX, 2018)
"These results suggest that the exposure during late pregnancy to a clinically relevant concentration of sevoflurane does not affect neuronal development and learning/memory ability of offspring mice."7.83Effects of sevoflurane exposure during late pregnancy on brain development of offspring mice. ( Maekawa, N; Mizobuchi, S; Morishita, J; Suehara, T; Ueki, M; Ueno, M, 2016)
" We describe a case of torsade de pointes (TdP) caused by sevoflurane in a patient with c-LQTS genotype 2 (LQT2)."7.83Sevoflurane-associated torsade de pointes in a patient with congenital long QT syndrome genotype 2. ( Hara, K; Kumakura, M; Sata, T, 2016)
"Inhalation anesthesia with sevoflurane during IVB treatment in premature infants with ROP may be appropriate for anesthetic management."7.79Inhalation anesthesia with sevoflurane during intravitreal bevacizumab injection in infants with retinopathy of prematurity. ( Celik, F; Ciftçi, T; Cınar, Y; Güzel, A; Sahin, A; Tokgöz, O; Tüfek, A; Yüksel, H, 2013)
"We report on a patient who developed two episodes of severe muscle rigidity, increased endtidal CO2 and increased creatine phosphate kinase associated with sevoflurane anesthesia."7.73Repeat episodes of severe muscle rigidity in a child receiving sevoflurane. ( Cohen, IT; Kaplan, R, 2006)
"Sevoflurane has favorable pharmacodynamic properties such as a rapid, smooth induction and emergence from anesthesia."5.30The use of sevoflurane anesthesia during early pregnancy. ( Fukuyama, H; Kanazawa, M; Kinefuchi, Y; Suzuki, T; Takiguchi, M, 1999)
"Sevoflurane anesthesia with laryngeal mask can achieve satisfactory anesthetic effects in cesarean section in women with heart disease."5.27[Application of sevoflurane and laryngeal mask in cesarean section in women with heart disease]. ( Ma, J; Wang, S; Wang, ZP; Wei, JF; Xu, JD; Yu, LN, 2018)
" Recently, we have found that sevoflurane anesthesia during pregnancy in mice-induced cognitive impairment in the offspring by causing iron deficiency and inhibiting myelinogenesis."5.12Prenatal sevoflurane exposure: Effects of iron metabolic dysfunction on offspring cognition and potential mechanism. ( Chang, Y; Shi, Z; Thirupathi, A; Zhou, C; Zuo, Y, 2021)
"In a prospective randomised study 52 ASA I patients scheduled for ambulatory pregnancy termination were premedicated with lorazepam and received alfentanil prior to anaesthesia induction with propofol (group P, n = 26) or with sevoflurane 8% (group S, n = 26) using the single breath vital capacity technique."5.08Comparison of sevoflurane and propofol for ambulatory anaesthesia in gynaecological surgery. ( Feiss, P; Lahrimi, A; Nathan, N; Peyclit, A, 1998)
"Mid-pregnancy exposure to sevoflurane led to excessive PARP-1 activation, poly (ADP-ribose) (PAR) polymer accumulation, apoptosis-inducing factor (AIF) nuclear translocation, and Nogo-A accumulation."4.12Sevoflurane exposure during the second trimester induces neurotoxicity in offspring rats by hyperactivation of PARP-1. ( Jiang, Q; Wang, C; Zhao, P, 2022)
" However, it's not clear whether RhoA pathway is involved in inhaled general anesthetics sevoflurane-induced synaptic development abnormalities and long-term cognitive dysfunction."4.02Inhibition of RhoA Activity Does Not Rescue Synaptic Development Abnormalities and Long-Term Cognitive Impairment After Sevoflurane Exposure. ( Huang, W; Huang, Z; Li, J; Li, Y; Liao, Z; Liu, Y; Miao, L, 2021)
"These results suggest that oxidative stress and reduced autophagy may underly ribbon-synapse involvement in sevoflurane-induced hearing loss."3.96Ribbon Synapses and Hearing Impairment in Mice After in utero Sevoflurane Exposure. ( Li, W; Li, Y; Liu, H; Shen, X; Yu, H; Yuan, X, 2020)
"To compare the effects of sevoflurane or propofol combined with remifentanil anesthesia on the clinical efficacy and stress response of pregnancy-induced hypertension (PIHS) in cesarean section."3.88Effects of sevoflurane or propofol combined with remifentanil anesthesia on clinical efficacy and stress response in pregnant women with pregnancy-induced hypertension. ( Guan, Y; Ren, LQ; Sun, XX, 2018)
" This study was conducted to investigate the mechanism of potential neurotoxicity on their offspring generation after sevoflurane anesthesia in adult animals during pregnancy based on metabolomics."3.85Potential neurotoxicity of prenatal exposure to sevoflurane on offspring: Metabolomics investigation on neurodevelopment and underlying mechanism. ( Jiang, J; Jin, Y; Li, S; Li, Y; Wang, Y; Xiao, X; Yan, S; Yang, Z, 2017)
" PROCEDURES Anesthesia was induced with propofol and maintained with sevoflurane."3.85Maternal and fetal effects of dexmedetomidine infusion in pregnant ewes anesthetized with sevoflurane. ( Barr, J; Lépiz, ML; Pashmakova, M; Sawant, O; Sayre, R; Washburn, K; Washburn, S, 2017)
" We describe a case of torsade de pointes (TdP) caused by sevoflurane in a patient with c-LQTS genotype 2 (LQT2)."3.83Sevoflurane-associated torsade de pointes in a patient with congenital long QT syndrome genotype 2. ( Hara, K; Kumakura, M; Sata, T, 2016)
"These results suggest that the exposure during late pregnancy to a clinically relevant concentration of sevoflurane does not affect neuronal development and learning/memory ability of offspring mice."3.83Effects of sevoflurane exposure during late pregnancy on brain development of offspring mice. ( Maekawa, N; Mizobuchi, S; Morishita, J; Suehara, T; Ueki, M; Ueno, M, 2016)
"Inhalation anesthesia with sevoflurane during IVB treatment in premature infants with ROP may be appropriate for anesthetic management."3.79Inhalation anesthesia with sevoflurane during intravitreal bevacizumab injection in infants with retinopathy of prematurity. ( Celik, F; Ciftçi, T; Cınar, Y; Güzel, A; Sahin, A; Tokgöz, O; Tüfek, A; Yüksel, H, 2013)
" Anesthesia was initiated with a volatile-based technique which, following delivery of the baby, was changed to target-controlled infusions of propofol and remifentanil."3.78Anesthetic management of a spontaneous spinal-epidural hematoma during pregnancy. ( Chang, YJ; Jo, YY; Kwak, HJ; Lee, D, 2012)
" The principal hypothesis, tested in chronically instrumented near-term pregnant ewes, was that sevoflurane anesthesia may be safe and useful for the mother and fetus during pregnancy, compared with isoflurane."3.75Comparison of the effects of sevoflurane and isoflurane anesthesia on the maternal-fetal unit in sheep. ( Morishima, HO; Okutomi, T; Stein, DJ; Whittington, RA, 2009)
"We report on a patient who developed two episodes of severe muscle rigidity, increased endtidal CO2 and increased creatine phosphate kinase associated with sevoflurane anesthesia."3.73Repeat episodes of severe muscle rigidity in a child receiving sevoflurane. ( Cohen, IT; Kaplan, R, 2006)
" The primary purpose of this study was to investigate the minimal alveolar concentration (MAC) of sevoflurane for cervical dilatation combined with different doses of dexmedetomidine in patients with hysteroscopy surgery."3.11Minimal alveolar concentration of sevoflurane in combination with dexmedetomidine in patients with hysteroscopy: An up-down sequential allocation study. ( Guo, YX; Jiang, PP; Luo, K; Wang, D; Wang, YZ; Yang, XL, 2022)
"Sevoflurane has favourable physical qualities for inhaled analgesia during labour pain."2.73Analgesia with sevoflurane during labour: i. Determination of the optimum concentration. ( Holdcroft, A; Stewart, A; Yentis, SM; Yeo, ST, 2007)
"0% progressive incremental dosing up to 1."2.70Intraoperative fetal oxygen saturation during Caesarean section: general anaesthesia using sevoflurane with either 100% oxygen or 50% nitrous oxide in oxygen. ( Capogna, G; Celleno, D; Fusco, P; Parpaglioni, R, 2002)
"The sevoflurane-treated offspring took longer than the control rats to find the MWM platform during the learning phase."1.91Prenatal Sevoflurane Exposure Impairs the Learning and Memory of Rat Offspring via HMGB1-Induced NLRP3/ASC Inflammasome Activation. ( Ding, X; Liu, H; Liu, P; Shan, Y; Yang, J; Zhou, Y, 2023)
"Sevoflurane could enhance 15LO2-PEBP1 interaction and activate ATM and its downstream P53/SAT1 pathway, which might be attributed to excessive p-ATM nuclear translocation."1.91Multiple sevoflurane exposures during mid-trimester induce neurotoxicity in the developing brain initiated by 15LO2-Mediated ferroptosis. ( Gao, Q; Jiang, Q; Wang, C; Wu, Z; Zhao, P, 2023)
"Sevoflurane is a safe and well-known inhaled anesthetic."1.72Effects of Sevoflurane Exposure on Fetal Brain Development Using Cerebral Organoids. ( Bae, DH; Bang, YS; Cho, CH; Choi, WH; Lee, JA; Yoo, J, 2022)
"Transversus abdominis plane block with subanesthetic concentrations of sevoflurane can provide effective and safe anesthesia in the cesarean section for a patient with ALS."1.62Transversus abdominis plane block provides effective and safe anesthesia in the cesarean section for an amyotrophic lateral sclerosis parturient: A case report. ( Chen, L; Jiang, J; Li, S; Wang, Y; Zhang, Y, 2021)
"Hydrocephalus is an active distension of the ventricular system of the brain."1.56Anaesthetic management of intracranial hypertension and pregnancy. A case report. ( Campos, MJ; Carreira, C; Norte, G; Órfão, R; Raimundo, A; Sampaio, A, 2020)
"Sevoflurane is a widely used volatile anesthetic in clinical practice."1.51Suberoylanilide hydroxamic acid (SAHA) alleviates the learning and memory impairment in rat offspring caused by maternal sevoflurane exposure during late gestation. ( Feng, N; Hu, Y; Li, M; Liu, Y; Liu, Z; Luo, F; Wu, L; Xu, L; Yu, Q; Zhao, W, 2019)
"Medetomidine effects were reversed using atipamezole hydrochloride at 50 μg/puppy sc immediately following delivery and in the bitch iv immediately following surgery."1.46Puppy survival and vigor associated with the use of low dose medetomidine premedication, propofol induction and maintenance of anesthesia using sevoflurane gas-inhalation for cesarean section in the bitch. ( De Cramer, KGM; Joubert, KE; Nöthling, JO, 2017)
"Sevoflurane-treated rats showed hyper-locomotion and impairment of working memory in the behavior tests."1.43A lasting effect of postnatal sevoflurane anesthesia on the composition of NMDA receptor subunits in rat prefrontal cortex. ( Shen, F; Xu, D; Zhang, X; Zhao, X, 2016)
"The corticosterone level was significantly increased immediately after repeated neonatal sevoflurane exposures."1.43Heightened stress response and cognitive impairment after repeated neonatal sevoflurane exposures might be linked to excessive GABAAR-mediated depolarization. ( Li, F; Liu, G; Qian, B; Qian, W; Zhang, A; Zhu, T, 2016)
"Thiopental was used in most cases for historical reasons (37%) or to reduce awareness (31%); other considerations included a clear end-point, dose predictability, cardiovascular stability, effects on the baby and drug licence concerns."1.39Choice of anaesthetic agents for caesarean section: a UK survey of current practice. ( Laxton, CH; Murdoch, H; Scrutton, M, 2013)
"Sevoflurane is a new inhalation anesthetic agent commonly used in the clinic."1.38Chronic exposure of gestation rat to sevoflurane impairs offspring brain development. ( Cheng, Y; Liu, G; Tian, X; Tu, X; Wang, J; Wang, Y, 2012)
"Sevoflurane concentration was adjusted to sustain a constant Bispectral Index (BIS) value of 40-55."1.37The effect of labor on sevoflurane requirements during cesarean delivery. ( Delatioglu, H; Erden, V; Erkalp, K; Kiroglu, S; Ortaküz, S; Ozdemir, B; Yangin, Z, 2011)
"Achondroplasia is the most common of these conditions."1.36Anesthetic management of achondroplastic dwarf undergoing cesarean section--a case report. ( Cevik, B; Colakoğlu, S, 2010)
"Sevoflurane was a vasodilator in the feto-placental vasculature in this in vitro model."1.35Sevoflurane and the feto-placental vasculature: the role of nitric oxide and vasoactive eicosanoids. ( Burke, P; Crowe, S; Farragher, R; Flynn, NM; Higgins, BD; Laffey, CD; Laffey, JG; Maharaj, CH, 2008)
"Propofol was intravenously administered at a bolus dose of 5 mg/kg and then infused a rate of 0."1.32Effects of propofol-sevoflurane anesthesia on the maternal and fetal hemodynamics blood gases, and uterine activity in pregnant goats. ( Fujiki, M; Misumi, K; Sakamoto, H; Setoyama, K; Shinzato, T, 2003)
"Pretreatment with isradipine (10(-6) M) or indomethacin (10(-7) M), concentrations that themselves had no effect on spontaneous contractility, significantly increased the inhibitor responses to sevoflurane on amplitude and frequency of myometrial contractions, beginning at 1 MAC (P<0."1.32Interactive effect of sevoflurane with isradipine or indomethacin on spontaneous contractile activity of isolated pregnant rat myometrium. ( Bagcivan, I; Gursoy, S; Kafali, H; Karadas, B; Kaya, T; Kunt, N, 2004)
"Sevoflurane responses were repeated at concentrations with no effect on spontaneous contractility of TEA, a Ca(2+)-activated K(+) channel blocker, and glibenclamide, an adenosine triphosphate-sensitive K(+) channel blocker, in myometrial strips."1.31The role of K(+) channels on the inhibitor effect of sevoflurane in pregnant rat myometrium. ( Bagcivan, I; Gürsoy, S; Kafali, H; Karadas, B; Kaya, T; Sarioglu, Y, 2002)
"A 28-year-old parturient with acute cortical blindness and eclampsia was scheduled for an emergency cesarean section."1.31[Emergency cesarean section in a patient with acute cortical blindness and eclampsia]. ( Fukuda, H; Hirabayashi, Y; Hiruta, A; Hiruta, M; Saitoh, K; Seo, N, 2002)
"Sevoflurane has favorable pharmacodynamic properties such as a rapid, smooth induction and emergence from anesthesia."1.30The use of sevoflurane anesthesia during early pregnancy. ( Fukuyama, H; Kanazawa, M; Kinefuchi, Y; Suzuki, T; Takiguchi, M, 1999)

Research

Studies (168)

TimeframeStudies, this research(%)All Research%
pre-19902 (1.19)18.7374
1990's15 (8.93)18.2507
2000's55 (32.74)29.6817
2010's57 (33.93)24.3611
2020's39 (23.21)2.80

Authors

AuthorsStudies
Gao, Y3
Zhao, T1
Chen, Y1
Sun, Z1
Lu, J1
Shi, Z3
Song, X1
Wang, Y6
Zhang, Y14
Li, S2
Chen, L2
Jiang, J2
Lian, JF1
Xu, YB1
Zheng, BY1
Shen, LY1
Liao, DY1
Zheng, C1
Lin, CL1
Huang, CB1
Luo, QC1
Guo, GQ1
Lin, XD1
Wu, JW1
Xiao, QS1
Liu, H7
Meng, X1
Li, Y6
Chen, S1
Ji, Y1
Song, S3
Ji, F3
Jin, X2
Song, R2
Wang, R2
Shen, Z1
Chu, H1
Yang, F3
Wu, X3
Tang, Z1
Fan, Z1
Liang, L1
Ma, R1
Xie, R1
Zhao, Y2
Zhang, M1
Guo, B1
Zeng, T1
He, D1
Zhao, X2
Zhang, H1
Wang, C2
Jiang, Q2
Zhao, P8
Guo, YX1
Luo, K1
Jiang, PP1
Wang, D1
Wang, YZ1
Yang, XL1
Kuai, S3
Xue, H4
Wu, Z6
Lee, JA2
Bae, DH2
Choi, WH2
Cho, CH2
Bang, YS2
Yoo, J2
Song, XY1
Liu, XW1
Wang, J7
Bleeser, T2
Basurto, D1
Russo, F1
Vergote, S1
Valenzuela, I1
Van den Broucke, S1
Kunpalin, Y1
Joyeux, L1
Van der Veeken, L2
Vally, JC1
Emam, D1
van der Merwe, J2
Van de Velde, M1
Devroe, S2
Deprest, J2
Rex, S2
Shan, Y3
Liu, P1
Zhou, Y1
Ding, X1
Yang, J2
Song, RX1
Miao, GS1
Dong, H1
Cai, M1
Peng, Y1
Miao, JK1
Lei, XF1
Yu, J1
Gao, Q1
Areias, J1
Sola, C1
Chastagnier, Y1
Pico, J1
Bouquier, N1
Dadure, C1
Perroy, J1
Szabo, V1
Zhou, B1
Liao, P1
Huang, L1
Chen, Z1
Liao, D1
Yang, L1
Yu, G1
Wang, L1
Zhang, J2
Zuo, Y3
Liu, J3
Jiang, R1
Chai, D3
Cheng, Y3
Sun, Y4
Yan, J3
Hu, R2
Zhang, L2
Jiang, H4
Hirotsu, A1
Iwata, Y1
Tatsumi, K1
Miyai, Y1
Matsuyama, T1
Tanaka, T1
Li, B1
Xie, J1
Ma, Z1
Thirupathi, A2
Yu, P1
Gao, G1
Zhou, J1
Zhou, C2
Xu, H1
Chang, Y2
Yu, Z2
Wang, H3
Cui, J2
Junzhang, P1
Sampaio, A1
Norte, G1
Campos, MJ1
Raimundo, A1
Carreira, C1
Órfão, R1
Li, C1
Yang, X1
Chen, B1
Liu, Y4
Cai, Y1
Tang, D1
Xu, S1
Gao, P1
Yu, W1
Jiao, Y1
Li, W3
Sun, H1
Hu, H1
Xu, X1
Tao, T1
Liang, Z1
Yuan, X1
Yu, H2
Shen, X2
Zhang, P2
Li, X2
Wan, Y1
Kimizuka, M1
Tokinaga, Y1
Azumaguchi, R1
Hamada, K1
Kazuma, S1
Yamakage, M2
Liao, Z1
Li, J3
Miao, L1
Huang, Z1
Huang, W1
Chen, Q2
Chu, W2
Sheng, R1
Jiang, M1
Tang, T1
Liang, X1
Qiu, Y1
Liu, S1
Bian, S1
Xie, Y1
Fang, F2
Cang, J2
Wang, HV1
Forestier, S1
Corces, VG1
Liu, M1
Sun, J1
Zhao, XK1
Tian, Y1
Cui, FH1
Li, KZ1
Xie, YG1
Zhao, XL1
Sabetian, G1
Zand, F2
Mirhadi, F1
Hadavi, MR1
Asadpour, E1
Dehghanpisheh, L1
Fattahi Saravi, Z1
Razavi, SM1
Shavit, CW1
Rollins, MD1
Ferschl, MB1
Xing, Q1
Han, XG1
Dong, X1
Lu, Y1
Zhou, M1
Lee, S1
Chung, W1
Park, H2
Yoon, S1
Park, S1
Park, J1
Heo, JY1
Ju, X1
Yoon, SH1
Kim, YH2
Ko, Y1
De Cramer, KGM1
Joubert, KE1
Nöthling, JO1
Tsukamoto, A1
Konishi, Y1
Kawakami, T1
Koibuchi, C1
Sato, R1
Kanai, E1
Inomata, T1
Xiao, X1
Jin, Y1
Yang, Z1
Yan, S1
Stolwijk, LJ1
Weeke, LC1
de Vries, LS1
van Herwaarden, MYA1
van der Zee, DC1
van der Werff, DBM1
Benders, MJNL1
Toet, M1
Lemmers, PMA1
Lépiz, ML1
Sayre, R1
Sawant, O1
Barr, J1
Pashmakova, M1
Washburn, K1
Washburn, S1
Mayorga-Buiza, MJ1
Marquez-Rivas, J1
Gomez-Gonzalez, E1
Yin, S1
Yang, Y1
Zhang, N1
Wang, ZP1
Ma, J1
Wang, S1
Yu, LN1
Wei, JF1
Xu, JD1
Ren, LQ1
Sun, XX1
Guan, Y1
Altıparmak, B1
Çelebi, N1
Canbay, Ö1
Toker, MK1
Kılıçarslan, B1
Aypar, Ü2
Xiao, Y1
Chen, K1
He, J1
Zhu, J1
Sun, S1
Shang, N1
Yu, Q1
Feng, N1
Hu, Y1
Luo, F1
Zhao, W2
Liu, Z1
Li, M1
Xu, L1
Wu, L1
Dong, Y2
Inversetti, A1
Galgano, A1
Meeusen, R1
Kong, X1
Bai, Q1
Liu, F1
Teng, L1
Kong, D1
Eckle, VS1
Hauser, S1
Drexler, B1
Antkowiak, B2
Grasshoff, C2
Cabezón, L1
Nogueira, C1
Ramos, L1
Vázquez-Fidalgo, A1
Tokgöz, O1
Sahin, A2
Tüfek, A1
Cınar, Y1
Güzel, A1
Ciftçi, T1
Celik, F1
Yüksel, H1
Yalcin, S1
Aydoğan, H1
Yuce, HH1
Kucuk, A1
Karahan, MA1
Vural, M1
Camuzcuoğlu, A1
Aksoy, N1
Takaenoki, Y1
Satoh, Y1
Araki, Y1
Kodama, M1
Yonamine, R1
Yufune, S1
Kazama, T1
Ye, Y1
Dong, Z1
Ni, R1
Zheng, L1
Ueki, R1
Tatara, T1
Kariya, N2
Shimode, N1
Hirose, M1
Tashiro, C1
Hadavi, SM1
Chohedri, A1
Sabetian, P1
Sanders, RD2
Absalom, A1
Sleigh, JW2
Gunduz, E1
Arun, O1
Bagci, ST1
Oc, B1
Salman, A1
Yilmaz, SA1
Celik, C1
Duman, A1
Micks, E1
Edelman, A1
Botha, R1
Bednarek, P1
Nichols, M1
Jensen, JT1
Moaveni, D1
Cohn, J1
Brodt, J1
Hoctor, K1
Ranasinghe, J1
Chen, P1
Sinha, A1
Suehara, T1
Morishita, J1
Ueki, M1
Ueno, M1
Maekawa, N1
Mizobuchi, S1
Zhang, X2
Shen, F1
Xu, D1
Liu, G2
Zhu, T1
Zhang, A1
Li, F1
Qian, W1
Qian, B1
Kumakura, M1
Hara, K1
Sata, T1
Lokhande, C1
Riad, I1
Tetzlaff, J1
Ayad, S1
Sasano, T1
Tomimatsu, T1
Kanagawa, T1
Kimura, T1
Yu, Y1
Xi, S1
Tomar, GS1
Goyal, K1
Chandran, R1
Luthra, A1
Chauhan, V1
Kumar, N1
Ling, X1
Peng, M1
Xue, Z2
Aydin, GB1
Coskun, F1
Farragher, R1
Maharaj, CH1
Higgins, BD1
Crowe, S1
Burke, P1
Laffey, CD1
Flynn, NM1
Laffey, JG1
Sun, A1
Rao, Y1
Wang, YL1
Li, H1
Zhang, W1
Gritsan, AI1
Gritsan, GV1
Sivkov, EN1
Shevchenko, YN1
Skorokhodova, TG1
Cortés Franco, MT1
Longás, VJ1
Cortés Franco, S1
Cuartero, LJ1
Okutomi, T1
Whittington, RA1
Stein, DJ1
Morishima, HO1
Hart, SM1
Buchannan, CR1
Alkan, S1
Tiraş, U1
Dallar, Y1
Sunay, D1
Erden, V1
Erkalp, K1
Yangin, Z1
Delatioglu, H1
Kiroglu, S1
Ortaküz, S1
Ozdemir, B1
Cevik, B1
Colakoğlu, S1
Tian, X1
Tu, X1
Suehiro, K1
Okutani, R1
Jo, YY1
Lee, D1
Chang, YJ1
Kwak, HJ1
Choi, WJ1
Kim, SH1
Koh, WU1
Hwang, DI1
Cho, SK1
Park, PH1
Han, SM1
Shin, JW1
Yang, T1
Zhuang, L1
Rei Fidalgo, AM1
Petrides, E1
Terrando, N1
Robertson, NJ1
Johnson, MR1
Maze, M1
Ma, D1
Sadana, N1
Houtchens, M1
Farber, MK1
Murdoch, H1
Scrutton, M1
Laxton, CH1
Liu, C1
Hu, K1
Zeng, M1
Luo, T1
Jiang, W1
Zheng, H1
Xu, Z1
Crosby, G1
Culley, DJ1
Xie, Z1
Hiruta, M1
Fukuda, H1
Hiruta, A1
Saitoh, K1
Hirabayashi, Y1
Seo, N1
Minoda, Y1
Yoshimine, K1
Nagata, E1
Takehara, A1
Kawaguchi, Y1
Ngan Kee, WD1
Khaw, KS1
Ma, KC1
Wong, AS1
Lee, BB1
Turner, RJ1
Lambrost, M1
Holmes, C1
Katz, SG1
Downs, CS1
Collins, DW1
Gatt, SP1
Kuczkowski, KM5
Trevisan, P1
Adams, HA1
Meyer, P1
Stoppa, A1
Müller-Goch, A1
Bayer, P1
Hecker, H1
Dogru, K2
Yildiz, K2
Dalgiç, H2
Sezer, Z2
Yaba, G1
Madenoglu, H2
Yamashita, K1
Yokoyama, T1
Tokai, H1
Imazu, Y1
Lee, M1
Manabe, M1
DAVITTI, L2
Setoyama, K1
Shinzato, T1
Misumi, K1
Fujiki, M1
Sakamoto, H1
Ong, BY1
Baron, K1
Stearns, EL1
Baron, C1
Paetkau, D1
Segstro, R1
Iyilikçi, L1
Erbayraktar, S1
Tural, AN1
Celik, M1
Sannav, S1
Ozcakir, HT1
Lacin, S1
Baytur, YB1
Lüleci, N1
Inceboz, US1
Chin, KJ2
Yeo, SW2
Dahlgren, G1
Törnberg, DC1
Pregner, K1
Irestedt, L1
Gursoy, S2
Kaya, T2
Kunt, N1
Karadas, B2
Bagcivan, I2
Kafali, H2
Aoki, A1
Hosono, Y1
Nishi, S1
Nishikawa, K1
Asada, A1
Matsuda, Y1
Kinouchi, K1
Kagawa, K1
Chun, BM1
Hiuge, Y1
Preckel, B1
Bolten, J1
Serin, IS1
Boyaci, A1
Jirasiritham, S1
Tantivitayatan, K1
Sirivararom, P1
Ducloy-Bouthors, AS1
Marciniak, B1
Vaast, P1
Fayoux, P1
Houfflin-Debarge, V1
Fily, A1
Rakza, T1
Yoo, KY2
Lee, JC1
Yoon, MH1
Shin, MH2
Kim, SJ2
Song, TB1
Lee, J2
Cohen, IT1
Kaplan, R1
McClure, JH1
Yeo, ST2
Holdcroft, A2
Yentis, SM2
Stewart, A2
Bassett, P1
McIver, T1
Jolley, D1
Pescod, D1
Fernández Sánchez, LJ1
Pérez González, R1
Guasch Arévalo, E1
Martín Reyes, R1
Gilsanz Rodríguez, F1
Manrique, S1
Blasco, J1
Munar, F1
Andreu, E1
Mateo, MD1
Suescun, MC1
López Gil, MV1
Grover, S1
Wilkinson, DJ1
Chang, LC1
Ohashi, Y1
Sumikura, H1
Tateda, T1
Palacio, FJ1
Ortiz-Gómez, JR1
Fornet, I1
López, MA1
Morillas, P1
Guasch, E1
Almogueraa, J1
Gilsanz, F1
Jeong, CW1
Kang, MW1
Chung, ST1
Gambling, DR2
Sharma, SK1
White, PF1
Van Beveren, T1
Bala, AS1
Gouldson, R1
Otaka, K1
Enzan, K1
Matsumoto, J1
Nagata, H1
Matsuura, S1
Suzuki, M1
Young, CJ1
Apfelbaum, JL1
Schaut, DJ1
Khona, R1
Gross, JB1
Klafta, JM1
Bhavani-Shankar, K1
Camann, WR1
Sitzman, BT1
Reisner, LS1
Maltby, JR1
Takahashi, K1
Sai, Y1
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Druzin, M1
Sarioglu, Y1
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Namiki, A1
Puig, NR1
Ferrero, P1
Bay, ML1
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Valenti, J1
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Elena, G1
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Parpaglioni, R1
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Fusco, P1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Brain Health & the Microbiome: A Proof-of-Concept Study in Patients With Mild Cognitive Impairment[NCT06039267]90 participants (Anticipated)Observational2023-08-25Recruiting
Effect of Sevoflurane on the Success of External Cephalic Version for Breech Presentation[NCT04346823]Phase 440 participants (Anticipated)Interventional2020-05-25Not yet recruiting
Sevoflurane as an Anesthetic During Dilation and Evacuation Procedures: Does it Increase Blood Loss and Interventions for Blood Loss and Why Do Anesthesiologists Choose to Use It?[NCT01048658]Phase 4160 participants (Actual)Interventional2009-09-30Completed
Comparing Pain Relief in Early Labor: Nitrous Oxide Versus Butorphonol Study[NCT01636999]0 participants (Actual)Interventional2012-09-30Withdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Experiencing Side Effects (Nausea, Dizziness)

(NCT01048658)
Timeframe: Post-procedure, within 30 minutes

InterventionParticipants (Count of Participants)
Sevoflurane13
No Sevoflurane11

Number of Participants Needing Intervention to Treat Blood Loss (a Composite of Use of Uterotonics, Re-aspiration, and Bimanual Massage)

Provider report for need to intervene due to blood loss (yes/no) (NCT01048658)
Timeframe: At time of uterine evacuation and immediately post-operatively, an average of 7.1 minutes

InterventionParticipants (Count of Participants)
Sevoflurane20
No Sevoflurane13

Number of Participants With Estimated Blood Loss Greater Than 300 mL (Yes/no)

Procedural blood loss greater than 300 mL. Blood loss was measured in a standardized fashion (amniotic fluid was discarded, blood was separated from tissue, and all gauze surgical drapes weighed). (NCT01048658)
Timeframe: At time of uterine evacuation, an average of 7.1 minutes

InterventionParticipants (Count of Participants)
Sevoflurane12
No Sevoflurane6

Procedure Time: T-test (Time of Speculum Placement to Time Speculum Removed)

Length of procedure from time of speculum placement to time of speculum removal, in minutes. (NCT01048658)
Timeframe: Time of speculum place to time of speculum removal, an average of 7.1 minutes

Interventionminutes (Mean)
Sevoflurane7.0
No Sevoflurane7.3

Patient and Provider Satisfaction With Anesthesia

Scores reported on 10-cm Visual Analog Scale (VAS anchors: 0= not satisfied at all, 10= completely satisfied) . Reported as mean +/- standard deviation. Subjects and providers were blinded to anesthesia method. Subjects and providers completed post-operative questionnaire within 30 minutes of procedure completion. (NCT01048658)
Timeframe: Post-procedure, within 30 minutes

,
Interventioncm (Mean)
Provider SatisfactionPatient Satisfaction
No Sevoflurane9.38.2
Sevoflurane9.48.4

Reviews

6 reviews available for sevoflurane and Pregnancy

ArticleYear
Prenatal sevoflurane exposure: Effects of iron metabolic dysfunction on offspring cognition and potential mechanism.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2021, Volume: 81, Issue:1

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Animals; Cognition Disorders; Female; Humans; I

2021
[Research Progress of Pharmacological Intervention of Sevoflurane-induced Nerve Injury in the Developing Brain].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2021, Jun-30, Volume: 43, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Apoptosis; Brain; Child; Female; Humans; Methyl Ethers; Neuroprote

2021
Fundamentals of fetal toxicity relevant to sevoflurane exposures during pregnancy.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2019, Volume: 72

    Topics: Anesthetics, Inhalation; Female; Fetus; Humans; Pregnancy; Pregnancy Complications; Prenatal Exposur

2019
Pharmacology of modern volatile anaesthetics.
    Best practice & research. Clinical anaesthesiology, 2005, Volume: 19, Issue:3

    Topics: Anesthetics, Inhalation; Desflurane; Female; Humans; Isoflurane; Methyl Ethers; Pregnancy; Sevoflura

2005
Adult clinical experience with sevoflurane and pharmaco-economic aspects.
    Acta anaesthesiologica Belgica, 1996, Volume: 47, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Anesthetics, Inhalation; Central Nervous System; Ethers; Female; Hea

1996
[Sevoflurane in obstetric anesthesia].
    Der Anaesthesist, 1998, Volume: 47 Suppl 1

    Topics: Anesthesia, Epidural; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics, Inhalation; Cesa

1998

Trials

21 trials available for sevoflurane and Pregnancy

ArticleYear
Comparison of the median effective concentration (EC50) and effect of sevoflurane with or without remifentanil in cesarean section with supreme laryngeal mask under narcotrend monitoring: a randomized trial.
    Annals of palliative medicine, 2021, Volume: 10, Issue:11

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Cesarean Section; Female; Humans; Laryngeal Masks

2021
Minimal alveolar concentration of sevoflurane in combination with dexmedetomidine in patients with hysteroscopy: An up-down sequential allocation study.
    Basic & clinical pharmacology & toxicology, 2022, Volume: 131, Issue:5

    Topics: Anesthetics, Inhalation; Dexmedetomidine; Female; Humans; Hysteroscopy; Methyl Ethers; Oxygen; Pregn

2022
Adequacy of maternal anesthesia depth with two sodium thiopental doses in elective caesarean section: a randomized clinical trial.
    BMC anesthesiology, 2021, 08-10, Volume: 21, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Anesthetics, Intravenous; Apgar Score; Cesarean Section; Consciousne

2021
[Application of sevoflurane and laryngeal mask in cesarean section in women with heart disease].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2018, Feb-20, Volume: 38, Issue:2

    Topics: Anesthesia; Blood Pressure; Cesarean Section; Female; Heart Diseases; Heart Rate; Humans; Infant, Ne

2018
Effect of magnesium sulfate on anesthesia depth, awareness incidence, and postoperative pain scores in obstetric patients. A double-blind randomized controlled trial.
    Saudi medical journal, 2018, Volume: 39, Issue:6

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics,

2018
Effects of sevoflurane and desflurane on oxidative stress during general anesthesia for elective cesarean section.
    Wiener klinische Wochenschrift, 2013, Volume: 125, Issue:15-16

    Topics: Adolescent; Adult; Anesthetics, General; Anesthetics, Inhalation; Cesarean Section; Desflurane; Elec

2013
The effect of sevoflurane on interventions for blood loss during dilation and evacuation procedures at 18-24 weeks of gestation: a randomized controlled trial.
    Contraception, 2015, Volume: 91, Issue:6

    Topics: Abortion, Induced; Adult; Anesthesia, General; Anesthetics, Inhalation; Blood Loss, Surgical; Dilata

2015
Influence of sevoflurane and desflurane on neurological and adaptive capacity scores in newborns.
    Saudi medical journal, 2008, Volume: 29, Issue:6

    Topics: Adaptation, Physiological; Adult; Anesthesia, Obstetrical; Anesthetics, Inhalation; Cesarean Section

2008
[Evalution of sevofluorane based low-flow anaesthesia quality during abdominal delevery].
    Khirurgiia, 2009, Issue:1

    Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Cesarean Section; Dose-Response Relationship

2009
Landiolol attenuates cardiovascular response at induction of general anesthesia for cesarean delivery.
    Journal of anesthesia, 2012, Volume: 26, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Anesthesia, General; Anesthesia, Obstetrical; Blood Pressure; Ce

2012
Effect of pre-exposure to sevoflurane on the bispectral index in women undergoing Caesarean delivery under general anaesthesia.
    British journal of anaesthesia, 2012, Volume: 108, Issue:6

    Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Inhalation; Awareness; Blood Press

2012
Randomized, double-blind comparison of different inspired oxygen fractions during general anaesthesia for Caesarean section.
    British journal of anaesthesia, 2002, Volume: 89, Issue:4

    Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Inhalation; Carbon Dioxide; Cesare

2002
[Anaesthesia for caesarean section. Comparison of two general anaesthetic regimens and spinal anaesthesia].
    Der Anaesthesist, 2003, Volume: 52, Issue:1

    Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics; Anesthetics, D

2003
Bispectral index values at sevoflurane concentrations of 1% and 1.5% in lower segment cesarean delivery.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:4

    Topics: Adult; Age Factors; Anesthesia, Inhalation; Anesthetics, Inhalation; Apgar Score; Cesarean Section;

2004
[General anesthesia by propofol infusion for delivery by cesarean section compared with sevoflurane anesthesia using bispectral index (BIS) monitoring].
    Masui. The Japanese journal of anesthesiology, 2005, Volume: 54, Issue:4

    Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Inhalation; Anesthetics, Intraveno

2005
Analgesia with sevoflurane during labour: ii. Sevoflurane compared with Entonox for labour analgesia.
    British journal of anaesthesia, 2007, Volume: 98, Issue:1

    Topics: Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Anesthetics, Inhalation; Conscious Sed

2007
Analgesia with sevoflurane during labour: i. Determination of the optimum concentration.
    British journal of anaesthesia, 2007, Volume: 98, Issue:1

    Topics: Adaptation, Psychological; Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Anesthetics

2007
Bispectral index values during sevoflurane-nitrous oxide general anesthesia in women undergoing cesarean delivery: a comparison between women with and without prior labor.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:6

    Topics: Adult; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Apgar Score; Blood Pressure; Brain;

2008
Use of sevoflurane during elective cesarean birth: a comparison with isoflurane and spinal anesthesia.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:1

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Inhalation;

1995
Comparison of sevoflurane and propofol for ambulatory anaesthesia in gynaecological surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:12

    Topics: Abortion, Induced; Activities of Daily Living; Adult; Ambulatory Surgical Procedures; Anesthesia, Ge

1998
Intraoperative fetal oxygen saturation during Caesarean section: general anaesthesia using sevoflurane with either 100% oxygen or 50% nitrous oxide in oxygen.
    European journal of anaesthesiology, 2002, Volume: 19, Issue:2

    Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Inhalation; Cesarean Section; Fema

2002

Other Studies

141 other studies available for sevoflurane and Pregnancy

ArticleYear
Prenatal sevoflurane exposure causes abnormal development of the entorhinal cortex in rat offspring.
    Journal of integrative neuroscience, 2021, Sep-30, Volume: 20, Issue:3

    Topics: Animals; Disease Models, Animal; Entorhinal Cortex; Female; GABA-A Receptor Agonists; Interneurons;

2021
Transversus abdominis plane block provides effective and safe anesthesia in the cesarean section for an amyotrophic lateral sclerosis parturient: A case report.
    Medicine, 2021, Oct-29, Volume: 100, Issue:43

    Topics: Abdominal Muscles; Adult; Amyotrophic Lateral Sclerosis; Anesthetics, Inhalation; Cesarean Section;

2021
Neonatal exposure to sevoflurane impairs preference for social novelty in C57BL/6 female mice at early-adulthood.
    Biochemical and biophysical research communications, 2022, 02-19, Volume: 593

    Topics: Animals; Animals, Newborn; Behavior, Animal; Cerebral Cortex; Female; Hippocampus; Male; Mice; Mice,

2022
Sevoflurane diminishes neurogenesis and promotes ferroptosis in embryonic prefrontal cortex via inhibiting nuclear factor-erythroid 2-related factor 2 expression.
    Neuroreport, 2022, 04-06, Volume: 33, Issue:6

    Topics: Female; Ferroptosis; Humans; Neurogenesis; NF-E2-Related Factor 2; Prefrontal Cortex; Pregnancy; Sev

2022
Neuroglobin alleviates the neurotoxicity of sevoflurane to fetal rats by inhibiting neuroinflammation and affecting microglial polarization.
    Brain research bulletin, 2022, 06-01, Volume: 183

    Topics: Animals; Female; Microglia; Neuroglobin; Neuroinflammatory Diseases; Neurotoxicity Syndromes; Pregna

2022
Maternal sevoflurane exposure disrupts oligodendrocyte myelination of the postnatal hippocampus and induces cognitive and motor impairments in offspring.
    Biochemical and biophysical research communications, 2022, 07-23, Volume: 614

    Topics: Animals; Cognition; Female; Hippocampus; Humans; Maternal Exposure; Mice; Mice, Inbred C57BL; Motor

2022
Sevoflurane exposure during the second trimester induces neurotoxicity in offspring rats by hyperactivation of PARP-1.
    Psychopharmacology, 2022, Volume: 239, Issue:9

    Topics: Anesthetics, Inhalation; Animals; Female; Focal Adhesion Kinase 2; Neurotoxicity Syndromes; Nogo Pro

2022
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
    Neurotoxicology, 2022, Volume: 93

    Topics: Animals; Cell Differentiation; Female; Hedgehog Proteins; Methyl Ethers; Neural Stem Cells; NF-E2-Re

2022
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
    Neurotoxicology, 2022, Volume: 93

    Topics: Animals; Cell Differentiation; Female; Hedgehog Proteins; Methyl Ethers; Neural Stem Cells; NF-E2-Re

2022
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
    Neurotoxicology, 2022, Volume: 93

    Topics: Animals; Cell Differentiation; Female; Hedgehog Proteins; Methyl Ethers; Neural Stem Cells; NF-E2-Re

2022
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
    Neurotoxicology, 2022, Volume: 93

    Topics: Animals; Cell Differentiation; Female; Hedgehog Proteins; Methyl Ethers; Neural Stem Cells; NF-E2-Re

2022
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
    Neurotoxicology, 2022, Volume: 93

    Topics: Animals; Cell Differentiation; Female; Hedgehog Proteins; Methyl Ethers; Neural Stem Cells; NF-E2-Re

2022
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
    Neurotoxicology, 2022, Volume: 93

    Topics: Animals; Cell Differentiation; Female; Hedgehog Proteins; Methyl Ethers; Neural Stem Cells; NF-E2-Re

2022
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
    Neurotoxicology, 2022, Volume: 93

    Topics: Animals; Cell Differentiation; Female; Hedgehog Proteins; Methyl Ethers; Neural Stem Cells; NF-E2-Re

2022
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
    Neurotoxicology, 2022, Volume: 93

    Topics: Animals; Cell Differentiation; Female; Hedgehog Proteins; Methyl Ethers; Neural Stem Cells; NF-E2-Re

2022
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
    Neurotoxicology, 2022, Volume: 93

    Topics: Animals; Cell Differentiation; Female; Hedgehog Proteins; Methyl Ethers; Neural Stem Cells; NF-E2-Re

2022
Effects of Sevoflurane Exposure on Fetal Brain Development Using Cerebral Organoids.
    Journal of molecular neuroscience : MN, 2022, Volume: 72, Issue:12

    Topics: Anesthetics, Inhalation; Brain; Female; Fetus; Humans; Organoids; Pregnancy; Sevoflurane

2022
Effects of Sevoflurane Exposure on Fetal Brain Development Using Cerebral Organoids.
    Journal of molecular neuroscience : MN, 2022, Volume: 72, Issue:12

    Topics: Anesthetics, Inhalation; Brain; Female; Fetus; Humans; Organoids; Pregnancy; Sevoflurane

2022
Effects of Sevoflurane Exposure on Fetal Brain Development Using Cerebral Organoids.
    Journal of molecular neuroscience : MN, 2022, Volume: 72, Issue:12

    Topics: Anesthetics, Inhalation; Brain; Female; Fetus; Humans; Organoids; Pregnancy; Sevoflurane

2022
Effects of Sevoflurane Exposure on Fetal Brain Development Using Cerebral Organoids.
    Journal of molecular neuroscience : MN, 2022, Volume: 72, Issue:12

    Topics: Anesthetics, Inhalation; Brain; Female; Fetus; Humans; Organoids; Pregnancy; Sevoflurane

2022
Suberoylanilide hydroxamic acid (SAHA) attenuates memory impairment in the offspring of rats exposed to sevoflurane anesthesia.
    Biochemical and biophysical research communications, 2023, 02-05, Volume: 643

    Topics: Anesthesia; Animals; Female; Hippocampus; Learning; Memory Disorders; MicroRNAs; Pregnancy; Rats; Se

2023
Effects of cumulative duration of repeated anaesthesia exposure on foetal brain development in the ovine model.
    Journal of clinical anesthesia, 2023, Volume: 85

    Topics: Anesthesia; Animals; Brain; Female; Fetus; Inflammation; Pregnancy; Sevoflurane; Sheep

2023
Prenatal Sevoflurane Exposure Impairs the Learning and Memory of Rat Offspring via HMGB1-Induced NLRP3/ASC Inflammasome Activation.
    ACS chemical neuroscience, 2023, 02-15, Volume: 14, Issue:4

    Topics: Amino Acid Transport System ASC; Animals; Female; Glycyrrhizic Acid; HMGB1 Protein; Inflammasomes; L

2023
Dexmedetomidine-mediated neuroprotection against sevoflurane-induced brain development abnormality in fetal mice brain.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:7

    Topics: Anesthetics; Anesthetics, Inhalation; Animals; Brain; Brain Diseases; Dexmedetomidine; Female; Mice;

2023
Prolonged Anesthesia Induction to Delivery Time Did Not Influence Plasma Remifentanil Concentration in Neonates.
    Drug design, development and therapy, 2023, Volume: 17

    Topics: Anesthesia, General; Anesthetics, Intravenous; Cesarean Section; Etomidate; Female; Humans; Infant,

2023
Multiple sevoflurane exposures during mid-trimester induce neurotoxicity in the developing brain initiated by 15LO2-Mediated ferroptosis.
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:10

    Topics: Animals; Brain; Female; Ferroptosis; Iron; Pregnancy; Rats; Rats, Sprague-Dawley; Sevoflurane

2023
Whole-brain characterization of apoptosis after sevoflurane anesthesia reveals neuronal cell death patterns in the mouse neonatal neocortex.
    Scientific reports, 2023, 09-07, Volume: 13, Issue:1

    Topics: Anesthesia, General; Animals; Apoptosis; Brain Death; Cell Death; Female; Mice; Neocortex; Pregnancy

2023
Astroglial dysfunctions drive aberrant synaptogenesis and social behavioral deficits in mice with neonatal exposure to lengthy general anesthesia.
    PLoS biology, 2019, Volume: 17, Issue:8

    Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Animals, Newborn; Astrocytes; Behavior, Anima

2019
Multiple sevoflurane exposures during pregnancy inhibit neuronal migration by upregulating prostaglandin D2 synthase.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2019, Volume: 78

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cell Movement; Cerebral Cortex; Female; Intramol

2019
Maternal exposure to volatile anesthetics induces IL-6 in fetal brains and affects neuronal development.
    European journal of pharmacology, 2019, Nov-15, Volume: 863

    Topics: Anesthetics, General; Animals; Behavior, Animal; Brain; Cell Line; Extracellular Signal-Regulated MA

2019
Sevoflurane anesthesia during pregnancy in mice induces cognitive impairment in the offspring by causing iron deficiency and inhibiting myelinogenesis.
    Neurochemistry international, 2020, Volume: 135

    Topics: Administration, Inhalation; Anemia, Iron-Deficiency; Anesthetics, Inhalation; Animals; Cognitive Dys

2020
Effects of Sevoflurane Exposure During Late Pregnancy on Brain Development and Beneficial Effects of Enriched Environment on Offspring Cognition.
    Cellular and molecular neurobiology, 2020, Volume: 40, Issue:8

    Topics: Anesthetics; Animals; Animals, Newborn; Brain; Cognition; Female; Long-Term Potentiation; Methyl Eth

2020
Anaesthetic management of intracranial hypertension and pregnancy. A case report.
    Revista espanola de anestesiologia y reanimacion, 2020, Volume: 67, Issue:4

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia; Anesthetics, Inhalation; Cesarean Section; Female; Fentany

2020
Sevoflurane inhibits neuronal migration and axon growth in the developing mouse cerebral cortex.
    Aging, 2020, 04-09, Volume: 12, Issue:7

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Antigens, Neoplasm; Axons; Cell Movement; Cerebr

2020
Maternal Treadmill Exercise Reduces the Neurotoxicity of Prenatal Sevoflurane Exposure in Rats via Activation of p300 Histone Acetyltransferase.
    Neurochemical research, 2020, Volume: 45, Issue:7

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; E1A-Associated p300 Protein; Exercise Test; Fema

2020
Hippocampus is more vulnerable to neural damages induced by repeated sevoflurane exposure in the second trimester than other brain areas.
    Acta biochimica et biophysica Sinica, 2020, Aug-05, Volume: 52, Issue:8

    Topics: Animals; Female; Hippocampus; Maternal Exposure; Maze Learning; Memory; Mice; Pregnancy; Prenatal Ex

2020
Key miRNAs associated with memory and learning disorder upon exposure to sevoflurane determined by RNA sequencing.
    Molecular medicine reports, 2020, Volume: 22, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Female; Hippocampus; Male; Maze Learning; Memory

2020
Ribbon Synapses and Hearing Impairment in Mice After in utero Sevoflurane Exposure.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Anesthetics, Inhalation; Animals; Autophagy; Cochlea; Female; Hearing Loss; Mice; Mice, Inbred C57BL

2020
Enriched environment improves sevoflurane-induced cognitive impairment during late-pregnancy via hippocampal histone acetylation.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2020, Volume: 53, Issue:10

    Topics: Acetylation; Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Female; Hippocampus;

2020
Maternal sevoflurane exposure affects differentiation of hippocampal neural stem cells by regulating miR-410-3p and ATN1.
    Stem cell research & therapy, 2020, 09-29, Volume: 11, Issue:1

    Topics: Animals; Cell Differentiation; Female; Hippocampus; MicroRNAs; Nerve Tissue Proteins; Neural Stem Ce

2020
Effects of anesthetic agents on contractions of the pregnant rat myometrium in vivo and in vitro.
    Journal of anesthesia, 2021, Volume: 35, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Female; Myometrium; Oxytocin; Pregnancy; Propofol; Rats; Sevoflura

2021
Inhibition of RhoA Activity Does Not Rescue Synaptic Development Abnormalities and Long-Term Cognitive Impairment After Sevoflurane Exposure.
    Neurochemical research, 2021, Volume: 46, Issue:3

    Topics: Amides; Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Cognitive Dysfunction; Dendri

2021
Maternal anesthesia with sevoflurane during the mid-gestation induces social interaction deficits in offspring C57BL/6 mice.
    Biochemical and biophysical research communications, 2021, 05-14, Volume: 553

    Topics: Aging; Anesthetics, Inhalation; Animals; Brain; Female; Male; Mice; Mice, Inbred C57BL; Mothers; Pre

2021
Maternal sevoflurane exposure induces temporary defects in interkinetic nuclear migration of radial glial progenitors in the fetal cerebral cortex through the Notch signalling pathway.
    Cell proliferation, 2021, Volume: 54, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Cell Line; Cell Movement; Cerebral Cortex; Female; Fetus; Humans;

2021
Exposure to sevoflurane results in changes of transcription factor occupancy in sperm and inheritance of autism†.
    Biology of reproduction, 2021, 09-14, Volume: 105, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Autism Spectrum Disorder; Female; Humans; Inheritance Patterns; Ma

2021
Gut microbiota mediates cognitive impairment in young mice after multiple neonatal exposures to sevoflurane.
    Aging, 2021, 06-28, Volume: 13, Issue:12

    Topics: Anesthesia; Animals; Anti-Bacterial Agents; Behavior, Animal; Cognitive Dysfunction; Feces; Female;

2021
Effects of sevoflurane exposure during different stages of pregnancy on the brain development of rat offspring.
    Journal of anesthesia, 2021, Volume: 35, Issue:5

    Topics: Animals; Female; Hippocampus; Learning; NF-kappa B; Pregnancy; Rats; Rats, Sprague-Dawley; Sevoflura

2021
Maternal convulsion during high-dose sevoflurane anaesthesia for open foetal surgery.
    British journal of anaesthesia, 2017, 04-01, Volume: 118, Issue:4

    Topics: Anesthetics, Inhalation; Female; Fetus; Humans; Intraoperative Complications; Meningomyelocele; Preg

2017
Sevoflurane anesthesia in pregnant rats negatively affects nerve function in offspring potentially via inhibition of the Wnt/β-catenin pathway.
    Molecular medicine reports, 2017, Volume: 15, Issue:5

    Topics: Anesthesia; Animals; beta Catenin; Female; Learning; Memory; Methyl Ethers; Nervous System; Pregnanc

2017
Single and multiple sevoflurane exposures during pregnancy and offspring behavior in mice.
    Paediatric anaesthesia, 2017, Volume: 27, Issue:7

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Excitatory Postsynapt

2017
Puppy survival and vigor associated with the use of low dose medetomidine premedication, propofol induction and maintenance of anesthesia using sevoflurane gas-inhalation for cesarean section in the bitch.
    Theriogenology, 2017, Jul-01, Volume: 96

    Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Animals, Newborn; Cesarean Section; Dogs; Fem

2017
Pharmacological properties of various anesthetic protocols in 10-day-old neonatal rats.
    Experimental animals, 2017, Oct-30, Volume: 66, Issue:4

    Topics: Anesthesia; Anesthetics, Combined; Animals; Animals, Newborn; Butorphanol; Dose-Response Relationshi

2017
Potential neurotoxicity of prenatal exposure to sevoflurane on offspring: Metabolomics investigation on neurodevelopment and underlying mechanism.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2017, Volume: 62

    Topics: Amino Acids; Anesthetics, Inhalation; Animals; Biomarkers; Blood Gas Analysis; Female; Male; Methyl

2017
Effect of general anesthesia on neonatal aEEG-A cohort study of patients with non-cardiac congenital anomalies.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Anesthesia, General; Brain; Congenital Abnormalities; Electroencephalography; Female; Humans; Infant

2017
Maternal and fetal effects of dexmedetomidine infusion in pregnant ewes anesthetized with sevoflurane.
    American journal of veterinary research, 2017, Volume: 78, Issue:11

    Topics: Anesthesia; Animals; Blood Pressure; Dexmedetomidine; Female; Fetus; Heart Rate; Hemodynamics; Infus

2017
Can fetus feel pain in the second trimester? Lessons learned from a sentinel event.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2018, Volume: 34, Issue:2

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-1 Receptor Agonists; Analgesics, Opioid; Anesthesia, General

2018
Mid-gestational sevoflurane exposure inhibits fetal neural stem cell proliferation and impairs postnatal learning and memory function in a dose-dependent manner.
    Developmental biology, 2018, 03-15, Volume: 435, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Cell Division; Cyclin D1; Dose-Response Relationship, Drug; Female

2018
Effects of sevoflurane or propofol combined with remifentanil anesthesia on clinical efficacy and stress response in pregnant women with pregnancy-induced hypertension.
    European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:6

    Topics: Adult; Anesthesia, Obstetrical; Blood Pressure; Cesarean Section; Female; Humans; Hypertension, Preg

2018
Sevoflurane anesthesia during pregnancy in mice induces hearing impairment in the offspring.
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Anesthetics, Inhalation; Animals; Evoked Potentials, Auditory, Brain Stem; Female; Hearing Loss; Mal

2018
Collapsin Response Mediator Protein-2 Ameliorates Sevoflurane-Mediated Neurocyte Injury by Targeting PI3K-mTOR-S6K Pathway.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Jul-18, Volume: 24

    Topics: Animals; Apoptosis; Cell Proliferation; Cell Survival; Cranial Nerve Injuries; Female; Hippocampus;

2018
Dexmedetomidine protects the developing rat brain against the neurotoxicity wrought by sevoflurane: role of autophagy and Drp1-Bax signaling.
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Animals; Animals, Newborn; Autophagy; bcl-2-Associated X Protein; Brain; Dexmedetomidine; Dynamins;

2018
Suberoylanilide hydroxamic acid (SAHA) alleviates the learning and memory impairment in rat offspring caused by maternal sevoflurane exposure during late gestation.
    The Journal of toxicological sciences, 2019, Volume: 44, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Cyclic AMP Response Element-Binding Protein; Female; Hippocampus;

2019
Neuroglobin protects offspring rats from neuronal damage induced by sevoflurane exposure to pregnant rats by inhibiting endogenous apoptosis.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2019, Volume: 76

    Topics: Anesthetics, Inhalation; Animals; Apoptosis; Brain; Brain Chemistry; Cytochromes c; Female; Hemin; H

2019
Maternal surgery during pregnancy has a transient adverse effect on the developing fetal rabbit brain.
    American journal of obstetrics and gynecology, 2019, Volume: 221, Issue:4

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis;

2019
Effects of general anesthesia with combined propofol and sevoflurane on descendant neurobehavioral, learning and memory functions in SD rats in their third trimester of pregnancy.
    Minerva medica, 2021, Volume: 112, Issue:4

    Topics: Anesthesia, General; Anesthetics, Combined; Animals; Avoidance Learning; Female; Maze Learning; Memo

2021
Opposing actions of sevoflurane on GABAergic and glycinergic synaptic inhibition in the spinal ventral horn.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Action Potentials; Anesthetics, Inhalation; Animals; Anterior Horn Cells; Female; GABA-A Receptor An

2013
[General anesthesia for an urgent cesarean in a pregnant woman with an acute cerebrovascular accident].
    Revista espanola de anestesiologia y reanimacion, 2014, Volume: 61, Issue:4

    Topics: Adult; Anesthesia, Obstetrical; Anesthetics, General; Balanced Anesthesia; Brain Ischemia; Carotid A

2014
Inhalation anesthesia with sevoflurane during intravitreal bevacizumab injection in infants with retinopathy of prematurity.
    BioMed research international, 2013, Volume: 2013

    Topics: Anesthesia; Antibodies, Monoclonal, Humanized; Bevacizumab; Female; Gestational Age; Humans; Infant,

2013
Neonatal exposure to sevoflurane in mice causes deficits in maternal behavior later in adulthood.
    Anesthesiology, 2014, Volume: 120, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Antioxidants; Enzyme-Linked Immunosorbent Assay;

2014
Anesthesia management for open fetal intrauterine surgery.
    Clinical and experimental obstetrics & gynecology, 2013, Volume: 40, Issue:3

    Topics: Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; Congenital Abnormalities; Cys

2013
Effect of decreased fetal perfusion on placental clearance of volatile anesthetics in a dual perfused human placental cotyledon model.
    Journal of anesthesia, 2014, Volume: 28, Issue:4

    Topics: Adult; Anesthetics, Inhalation; Cesarean Section; Female; Fetus; Humans; Infant, Newborn; Isoflurane

2014
Survey on the adequacy of depth of anaesthesia with bispectral index and isolated forearm technique in elective Caesarean section under general anaesthesia with sevoflurane.
    British journal of anaesthesia, 2014, Volume: 112, Issue:5

    Topics: Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Inhalation; Awareness; Cesarean Section;

2014
V. 'For now we see through a glass, darkly': the anaesthesia syndrome.
    British journal of anaesthesia, 2014, Volume: 112, Issue:5

    Topics: Anesthesia, General; Anesthesia, Obstetrical; Awareness; Cesarean Section; Electroencephalography; F

2014
Effects of propofol and sevoflurane on isolated human umbilical arteries pre-contracted with dopamine, adrenaline and noradrenaline.
    The journal of obstetrics and gynaecology research, 2015, Volume: 41, Issue:5

    Topics: Adult; Anesthetics, Intravenous; Dopamine; Epinephrine; Female; Humans; Methyl Ethers; Norepinephrin

2015
Scleroderma and pulmonary hypertension complicating two pregnancies: use of neuraxial anesthesia, general anesthesia, epoprostenol and a multidisciplinary approach for cesarean delivery.
    International journal of obstetric anesthesia, 2015, Volume: 24, Issue:4

    Topics: Adult; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Obstetrical; Anesthesia, Spinal; Anest

2015
Anaesthetic management of a parturient with factor VII deficiency and sepsis.
    International journal of obstetric anesthesia, 2015, Volume: 24, Issue:4

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Cesarean Section; Factor VII Deficiency; Female

2015
Effects of sevoflurane exposure during late pregnancy on brain development of offspring mice.
    Paediatric anaesthesia, 2016, Volume: 26, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Caspase 3; Fe

2016
A lasting effect of postnatal sevoflurane anesthesia on the composition of NMDA receptor subunits in rat prefrontal cortex.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2016, Volume: 54

    Topics: Age Factors; Anesthetics, Inhalation; Animals; Animals, Newborn; Exploratory Behavior; Female; Gene

2016
Heightened stress response and cognitive impairment after repeated neonatal sevoflurane exposures might be linked to excessive GABAAR-mediated depolarization.
    Journal of anesthesia, 2016, Volume: 30, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Bumetanide; Cognitive Dysfunction; Corticosteron

2016
Sevoflurane-associated torsade de pointes in a patient with congenital long QT syndrome genotype 2.
    Journal of clinical anesthesia, 2016, Volume: 33

    Topics: Abortion, Therapeutic; Adult; Anesthetics, Inhalation; Electrocardiography; Female; Genotype; Humans

2016
The peri-operative management of a cesarean section in a patient with Goldenhar syndrome (GS): A case report.
    Journal of clinical anesthesia, 2016, Volume: 34

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Bupivacaine; Cesarean Section; Female; Goldenha

2016
Neglected shoulder presentation with foetal death managed by internal podalic version with nitroglycerine and sevoflurane.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2017, Volume: 37, Issue:1

    Topics: Abruptio Placentae; Adult; Anesthetics, Inhalation; Female; Fetal Death; Humans; Labor Presentation;

2017
Sevoflurane induces cognitive impairments via the MiR-27b/LIMK1-signaling pathway in developing rats.
    Inhalation toxicology, 2016, Volume: 28, Issue:14

    Topics: Anesthetics, Inhalation; Animals; Behavior, Animal; Cells, Cultured; Cognitive Dysfunction; Fear; Fe

2016
Aneurysmal hemorrhage in a pregnant patient with coarctation of aorta: An anesthetic challenge.
    Journal of clinical anesthesia, 2017, Volume: 37

    Topics: Adult; Anesthesia, General; Aortic Coarctation; Craniotomy; Female; Fentanyl; Humans; Intracranial A

2017
Multiple sevoflurane anesthesia in pregnant mice inhibits neurogenesis of fetal hippocampus via repressing transcription factor Pax6.
    Life sciences, 2017, Apr-15, Volume: 175

    Topics: Anesthesia; Animals; Cells, Cultured; Cyclin D1; Female; Fetus; Hippocampus; Learning; Maternal Expo

2017
Sevoflurane and the feto-placental vasculature: the role of nitric oxide and vasoactive eicosanoids.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:1

    Topics: Anesthetics, Inhalation; Dose-Response Relationship, Drug; Eicosanoids; Female; Fetus; Humans; In Vi

2008
Subclinical concentration of sevoflurane potentiates neuronal apoptosis in the developing C57BL/6 mouse brain.
    Neuroscience letters, 2008, Dec-12, Volume: 447, Issue:2-3

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Brain; Caspase 3; DNA, Single-Strande

2008
Effects of pregnancy on the solubility of halogenated volatile anaesthetics in rat blood and tissues.
    Anaesthesia and intensive care, 2008, Volume: 36, Issue:6

    Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Brain; Chromatography, Gas; Female; Halothan

2008
[Ventriculo-peritoneal shunt valve malfunction in a pregnant woman at full-term].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:4

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics; Cesarean Section; Consciousness

2009
Comparison of the effects of sevoflurane and isoflurane anesthesia on the maternal-fetal unit in sheep.
    Journal of anesthesia, 2009, Volume: 23, Issue:3

    Topics: Acid-Base Equilibrium; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Gas Analysis;

2009
A failure of M-Entropy to correctly detect burst suppression leading to sevoflurane overdosage.
    Anaesthesia and intensive care, 2009, Volume: 37, Issue:6

    Topics: Adult; Anesthesia, Obstetrical; Anesthetics, Inhalation; Cesarean Section; Drug Overdose; Electroenc

2009
Effect of anaesthetic agents administered to the mothers on transcutaneous bilirubin levels in the neonates.
    Acta paediatrica (Oslo, Norway : 1992), 2010, Volume: 99, Issue:7

    Topics: Adult; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics; Bilirubin;

2010
The effect of labor on sevoflurane requirements during cesarean delivery.
    International journal of obstetric anesthesia, 2011, Volume: 20, Issue:1

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Apgar Score; Carbon Dioxide; Cesarean Section;

2011
Anesthetic management of achondroplastic dwarf undergoing cesarean section--a case report.
    Middle East journal of anaesthesiology, 2010, Volume: 20, Issue:6

    Topics: Achondroplasia; Adult; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Inhalation; Anesth

2010
Chronic exposure of gestation rat to sevoflurane impairs offspring brain development.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2012, Volume: 33, Issue:3

    Topics: Age Factors; Anesthetics, Inhalation; Animals; Apoptosis; Blood Gas Analysis; Brain; Female; GAP-43

2012
Anesthetic management of a spontaneous spinal-epidural hematoma during pregnancy.
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:2

    Topics: Adult; Androstanols; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Back Pain; Cesar

2012
Xenon and sevoflurane provide analgesia during labor and fetal brain protection in a perinatal rat model of hypoxia-ischemia.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Analgesia; Animals; Animals, Newborn; Apoptosis; Brain; Caspase 3; Cell Survival; Cohort Studies; Fe

2012
Anesthetic management of a parturient with neuromyelitis optica.
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Analgesics, Opioid; Androstanols; Anesthesia, General; Anesthesia, O

2012
Choice of anaesthetic agents for caesarean section: a UK survey of current practice.
    International journal of obstetric anesthesia, 2013, Volume: 22, Issue:1

    Topics: Anesthesia, Obstetrical; Anesthetics; Anesthetics, Inhalation; Anesthetics, Intravenous; Cesarean Se

2013
Sevoflurane induces short-term changes in proteins in the cerebral cortices of developing rats.
    Acta anaesthesiologica Scandinavica, 2013, Volume: 57, Issue:3

    Topics: Adenosine Triphosphatases; Anesthesia; Anesthetics, Inhalation; Animals; Animals, Newborn; Blotting,

2013
Sevoflurane anesthesia in pregnant mice induces neurotoxicity in fetal and offspring mice.
    Anesthesiology, 2013, Volume: 118, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Brain; Female; Maze Learning; Methyl Ethers; Mic

2013
[Emergency cesarean section in a patient with acute cortical blindness and eclampsia].
    Masui. The Japanese journal of anesthesiology, 2002, Volume: 51, Issue:6

    Topics: Acute Disease; Adult; Anesthesia, General; Anesthesia, Obstetrical; Blindness, Cortical; Cesarean Se

2002
[Anesthetic factors that influence pH of neonatal umbilical artery from mothers in severe gestosis during cesarean section under sevoflurane anesthesia].
    Masui. The Japanese journal of anesthesiology, 2002, Volume: 51, Issue:8

    Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Birth Weight; Blood Pressure; Cesarean Section;

2002
The effects of sevoflurane on isolated gravid human myometrium.
    Anaesthesia and intensive care, 2002, Volume: 30, Issue:5

    Topics: Analysis of Variance; Anesthesia, Obstetrical; Culture Techniques; Dose-Response Relationship, Drug;

2002
Seizures on emergence from sevoflurane anaesthesia for Caesarean section in a healthy parturient.
    Anaesthesia, 2002, Volume: 57, Issue:12

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics, Inh

2002
Fibre-optic awake intubation for caesarean section in a parturient with predicted difficult airway.
    Minerva anestesiologica, 2002, Volume: 68, Issue:10

    Topics: Administration, Intranasal; Adult; Anesthesia, Inhalation; Anesthesia, Local; Anesthesia, Obstetrica

2002
Inhibitory effects of desflurane and sevoflurane on contractions of isolated gravid rat myometrium under oxytocin stimulation.
    Acta anaesthesiologica Scandinavica, 2003, Volume: 47, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Desflurane; Dose-Response Relationship, Drug; Female; In Vitro Tec

2003
[Anesthetic management for a patient with multiple sclerosis at exacerbation stage under general anesthesia].
    Masui. The Japanese journal of anesthesiology, 2003, Volume: 52, Issue:5

    Topics: Adult; Anesthesia, General; Dilatation and Curettage; Female; Humans; Methyl Ethers; Monitoring, Phy

2003
[Psychophysical labor; experience of a sojourn in France].
    Minerva ginecologica, 1955, Jun-30, Volume: 7, Issue:12

    Topics: Female; France; Humans; Labor, Obstetric; Methyl Ethers; Pregnancy; Sevoflurane

1955
[Psycho-physical labor; experience during a sojourn in France].
    Minerva ginecologica, 1955, Mar-15, Volume: 7, Issue:5

    Topics: Female; France; Humans; Labor, Obstetric; Methyl Ethers; Physical Examination; Pregnancy; Sevofluran

1955
Inhalation induction of anesthesia with sevoflurane for emergency Cesarean section in an amphetamine-intoxicated parturient without an intravenous access.
    Acta anaesthesiologica Scandinavica, 2003, Volume: 47, Issue:9

    Topics: Adult; Amphetamine-Related Disorders; Anesthesia, Inhalation; Anesthesia, Obstetrical; Cesarean Sect

2003
Effects of propofol-sevoflurane anesthesia on the maternal and fetal hemodynamics blood gases, and uterine activity in pregnant goats.
    The Journal of veterinary medical science, 2003, Volume: 65, Issue:10

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Pressure; Conscious Sedation; Drug

2003
Severe fetal bradycardia in a pregnant surgical patient despite normal oxygenation and blood pressure.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2003, Volume: 50, Issue:9

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Apgar Score; Blood Pr

2003
Anesthetic management of lumbar discectomy in a pregnant patient.
    Journal of anesthesia, 2004, Volume: 18, Issue:1

    Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Inhalation; Female; Humans; Interv

2004
Different anesthesiologic strategies have no effect on neonatal jaundice.
    Archives of gynecology and obstetrics, 2004, Volume: 270, Issue:3

    Topics: Anesthesia, Epidural; Anesthesia, General; Anesthesia, Obstetrical; Apgar Score; Bilirubin; Bupivaca

2004
Four cases of the ex utero intrapartum treatment (EXIT) procedure: anesthetic implications.
    International journal of obstetric anesthesia, 2004, Volume: 13, Issue:3

    Topics: Adult; Airway Obstruction; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics, Inhalation;

2004
Sevoflurane and seizures: déjà vu.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:9

    Topics: Adult; Anesthetics, Inhalation; Female; Humans; Intraoperative Complications; Methyl Ethers; Pregnan

2004
Interactive effect of sevoflurane with isradipine or indomethacin on spontaneous contractile activity of isolated pregnant rat myometrium.
    International journal of obstetric anesthesia, 2004, Volume: 13, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers;

2004
A BIS-guided study of sevoflurane requirements for adequate depth of anaesthesia in Caesarean section.
    Anaesthesia, 2004, Volume: 59, Issue:11

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics, Inhalation; Awareness; Blood Pr

2004
Propofol and sevoflurane depress spinal neurons in vitro via different molecular targets.
    Anesthesiology, 2004, Volume: 101, Issue:5

    Topics: Action Potentials; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Bicuculline; Cells, C

2004
[Anesthetic management of the ex-utero intrapartum treatment (EXIT) procedure for congenital high airway obstruction syndrome (CHAOS)].
    Masui. The Japanese journal of anesthesiology, 2005, Volume: 54, Issue:5

    Topics: Adult; Airway Obstruction; Anesthesia, General; Anesthesia, Obstetrical; Female; Fetal Monitoring; F

2005
Inhibitory effects of desflurane and sevoflurane on oxytocin-induced contractions of isolated pregnant human myometrium.
    Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:9

    Topics: Adult; Anesthetics, Inhalation; Desflurane; Female; Humans; In Vitro Techniques; Isoflurane; Methyl

2005
Over half MAC sevoflurane in cesarean section.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2005, Volume: 88, Issue:7

    Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Inhalation; Awareness; Cesarean Se

2005
[Maternal and foetal anaesthesia for ex utero intrapartum treatment (EXIT) procedure].
    Annales francaises d'anesthesie et de reanimation, 2006, Volume: 25, Issue:6

    Topics: Adult; Airway Obstruction; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics, Inhalation;

2006
The effects of volatile anesthetics on spontaneous contractility of isolated human pregnant uterine muscle: a comparison among sevoflurane, desflurane, isoflurane, and halothane.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:2

    Topics: Anesthetics, Inhalation; Calcium; Desflurane; Dose-Response Relationship, Drug; Female; Glyburide; H

2006
Repeat episodes of severe muscle rigidity in a child receiving sevoflurane.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:10

    Topics: Abnormalities, Multiple; Anesthetics, Inhalation; Arrhythmias, Cardiac; Carbon Dioxide; Creatine Kin

2006
Sevoflurane analgesia in labour (Sevo'n'ox).
    British journal of anaesthesia, 2007, Volume: 98, Issue:1

    Topics: Analgesia, Obstetrical; Anesthetics, Inhalation; Drug Administration Schedule; Female; Humans; Methy

2007
General anaesthesia and Caesarean section for a patient with hereditary spastic paraparesis (Strumpell's disease).
    International journal of obstetric anesthesia, 2007, Volume: 16, Issue:2

    Topics: Adult; Androstanols; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Inhalation; Anesthet

2007
[Perioperative treatment of a pregnant woman with recent cerebral infarction secondary to noncompaction cardiomyopathy].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:10

    Topics: Adrenergic beta-Antagonists; Androstanols; Anesthesia, General; Anesthesia, Inhalation; Anesthesia,

2006
[Two cases of congenital airway obstruction managed with ex utero intrapartum treatment procedures: anesthetic implications].
    Revista espanola de anestesiologia y reanimacion, 2007, Volume: 54, Issue:1

    Topics: Adult; Airway Obstruction; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics, Inhalation;

2007
Anesthetic implications of botulinum toxin type A (Botox) injections for the treatment of 'the aging face' in the parturient.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:4

    Topics: Adult; Aging; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics,

2007
Sevoflurane and analgesia.
    British journal of anaesthesia, 2007, Volume: 98, Issue:5

    Topics: Analgesia, Obstetrical; Anesthetics, Inhalation; Female; Humans; Methyl Ethers; Pain; Pregnancy; Sev

2007
The ex utero intrapartum treatment procedure: anesthetic considerations.
    Archives of gynecology and obstetrics, 2008, Volume: 277, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Anesthesia, General; Anesthetics, Inhalation; Fema

2008
Inhibitory effect of alprostadil against sevoflurane-induced myometrial relaxation in rats.
    Journal of anesthesia, 2007, Volume: 21, Issue:3

    Topics: Alprostadil; Anesthetics, Inhalation; Animals; Area Under Curve; Dose-Response Relationship, Drug; F

2007
[Remifentanil bolus for cesarean section in high-risk patients: study of 12 cases].
    Revista espanola de anestesiologia y reanimacion, 2008, Volume: 55, Issue:2

    Topics: Adult; Anesthetics, Intravenous; Atracurium; Cesarean Section; Female; Fentanyl; Fetus; Hemodynamics

2008
[Convulsions after a test dose of ropivacaine and negative aspiration test for combined spinal-epidural analgesia for cesarean section].
    Revista espanola de anestesiologia y reanimacion, 2008, Volume: 55, Issue:2

    Topics: Adult; Amides; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Bupivacaine; Cesar

2008
[Anesthetic management for cesarean section and clipping of aneurysm in a pregnant woman with ruptured cerebral aneurysm].
    Masui. The Japanese journal of anesthesiology, 1993, Volume: 42, Issue:6

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics; Cesarean Section; Ethers; Femal

1993
Sevoflurane inhalation induction for emergency cesarean section in a parturient with no intravenous access.
    Anesthesiology, 1997, Volume: 86, Issue:6

    Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Inhalation; Cesarean Section; Emer

1997
The practice of using sevoflurane inhalation induction for emergency cesarean section and a parturient with no intravenous access.
    Anesthesiology, 1998, Volume: 88, Issue:1

    Topics: Anesthesia, Obstetrical; Anesthetics, Inhalation; Cesarean Section; Emergencies; Ethers; Female; Hum

1998
The practice of using sevoflurane inhalation induction for emergency cesarean section and a parturient with no intravenous access.
    Anesthesiology, 1998, Volume: 88, Issue:1

    Topics: Anesthesia, Obstetrical; Anesthetics, Inhalation; Cesarean Section; Emergencies; Ethers; Female; Hum

1998
The practice of using sevoflurane inhalation induction for emergency cesarean section and a parturient with no intravenous access.
    Anesthesiology, 1998, Volume: 88, Issue:1

    Topics: Anesthesia, Obstetrical; Anesthetics, Inhalation; Cesarean Section; Emergencies; Ethers; Female; Hum

1998
The practice of using sevoflurane inhalation induction for emergency cesarean section and a parturient with no intravenous access.
    Anesthesiology, 1998, Volume: 88, Issue:1

    Topics: Anesthesia, Obstetrical; Anesthetics, Inhalation; Cesarean Section; Emergencies; Ethers; Female; Hum

1998
The practice of using sevoflurane inhalation induction for emergency cesarean section and a parturient with no intravenous access.
    Anesthesiology, 1998, Volume: 88, Issue:1

    Topics: Anesthesia, Obstetrical; Anesthetics, Inhalation; Cesarean Section; Emergencies; Ethers; Female; Hum

1998
Anaesthetic management for caesarean section combined with removal of phaeochromocytoma.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:3

    Topics: Adrenal Gland Neoplasms; Adult; Alprostadil; Anesthesia, Epidural; Anesthesia, General; Anesthesia,

1998
[Occupational exposure in the hospital to laughing gas and the new inhalation anesthetics desflurane and sevoflurane].
    Deutsche medizinische Wochenschrift (1946), 1999, Feb-12, Volume: 124, Issue:6

    Topics: Air Conditioning; Anesthetics, Inhalation; Desflurane; Female; Germany; Humans; Intensive Care Units

1999
Sevoflurane induction for emergency cesarean section in a parturient in status asthmaticus.
    Anesthesiology, 1999, Volume: 90, Issue:5

    Topics: Adult; Anesthesia, Obstetrical; Anesthetics, Inhalation; Cesarean Section; Emergencies; Female; Huma

1999
The use of sevoflurane anesthesia during early pregnancy.
    The Tokai journal of experimental and clinical medicine, 1999, Volume: 24, Issue:2

    Topics: Adult; Anesthetics, Inhalation; Female; Humans; Ileal Diseases; Intestinal Obstruction; Methyl Ether

1999
Mask induction with sevoflurane in a parturient with severe tracheal stenosis.
    Anesthesiology, 2001, Volume: 95, Issue:2

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics, Inhalation; Bronchoscopy; Cesar

2001
The role of K(+) channels on the inhibitor effect of sevoflurane in pregnant rat myometrium.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:1

    Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Female;

2002
Sevoflurane inhibits contraction of uterine smooth muscle from pregnant rats similarly to halothane and isoflurane.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2002, Volume: 49, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Barium; Calcium; Calcium Channels; Female; Fluorescent Dyes; Fura-

2002
Effects of sevoflurane general anesthesia: immunological studies in mice.
    International immunopharmacology, 2002, Volume: 2, Issue:1

    Topics: Adjuvants, Immunologic; Anesthesia, General; Anesthetics, Inhalation; Animals; B-Lymphocytes; Blood

2002
Monitoring of the anaesthetic volatile agent may be impaired in hydrocarbons abusers.
    Anaesthesia, 2002, Volume: 57, Issue:5

    Topics: Abortion, Missed; Adult; Anesthetics; Butanes; Emergencies; Female; Humans; Methyl Ethers; Monitorin

2002