sevoflurane has been researched along with Parkinson Disease in 5 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| " During induction of anesthesia with propofol (n = 13) or sevoflurane (n = 12) alone, cortical (EEG) and subcortical (ESCoG) electrogenesis were obtained, respectively, from a frontal montage (F3-C3) and through the deep-brain electrode (p0-p3)." | 5.12 | Differential dynamic of action on cortical and subcortical structures of anesthetic agents during induction of anesthesia. ( Bruder, NJ; Gouin, FM; Gouvitsos, FA; Peragut, JC; Regis, JM; Rey, MF; Velly, LJ; Witjas, T, 2007) |
| "An increasing number of patients with Parkinson's disease (PD) will have surgery under general anesthesia." | 3.01 | Minimum Alveolar Concentration-Awake of Sevoflurane is Decreased in Patients with Parkinson's Disease: An Up-and-Down Sequential Allocation Trial. ( Dong, M; Huang, X; Kang, F; Li, J; Meng, W; Wang, S; Yang, C; Zuo, Z, 2021) |
| "Twelve patients with similar Parkinson's disease severity received desflurane (n=6) or sevoflurane (n=6) during DBS surgery." | 1.62 | Desflurane and sevoflurane differentially affect activity of the subthalamic nucleus in Parkinson's disease. ( Chen, SY; Chen, TY; Chen, YC; Pan, JI; Tsai, ST, 2021) |
| "A cohort of 19 patients with Parkinson's disease with comparable disability underwent placement of electrodes under either sevoflurane general anesthesia (n = 10) or local anesthesia (n = 9)." | 1.56 | Sevoflurane and Parkinson's Disease: Subthalamic Nucleus Neuronal Activity and Clinical Outcome of Deep Brain Stimulation. ( Chen, SY; Chen, TY; Kuo, CC; Tsai, ST; Tseng, GF, 2020) |
| "Patients with Parkinson's disease (PD) often require surgery, and therefore may receive inhalation anesthesia." | 1.42 | Effects of sevoflurane on leucine-rich repeat kinase 2-associated Drosophila model of Parkinson's disease. ( Cai, S; Gu, H; Kuang, L; Shan, Z; Wang, Q; Wen, J; Xiu, H; Xu, K; Zhang, T, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsai, ST | 2 |
| Tseng, GF | 1 |
| Kuo, CC | 1 |
| Chen, TY | 2 |
| Chen, SY | 2 |
| Chen, YC | 1 |
| Pan, JI | 1 |
| Yang, C | 1 |
| Kang, F | 1 |
| Meng, W | 1 |
| Dong, M | 1 |
| Huang, X | 1 |
| Wang, S | 1 |
| Zuo, Z | 1 |
| Li, J | 1 |
| Shan, Z | 1 |
| Cai, S | 1 |
| Zhang, T | 1 |
| Kuang, L | 1 |
| Wang, Q | 1 |
| Xiu, H | 1 |
| Wen, J | 1 |
| Gu, H | 1 |
| Xu, K | 1 |
| Velly, LJ | 1 |
| Rey, MF | 1 |
| Bruder, NJ | 1 |
| Gouvitsos, FA | 1 |
| Witjas, T | 1 |
| Regis, JM | 1 |
| Peragut, JC | 1 |
| Gouin, FM | 1 |
2 trials available for sevoflurane and Parkinson Disease
| Article | Year |
|---|---|
Minimum Alveolar Concentration-Awake of Sevoflurane is Decreased in Patients with Parkinson's Disease: An Up-and-Down Sequential Allocation Trial.
Topics: Anesthesia; Anesthesia Recovery Period; Anesthetics; Anesthetics, Inhalation; Dose-Response Relation | 2021 |
Differential dynamic of action on cortical and subcortical structures of anesthetic agents during induction of anesthesia.
Topics: Aged; Anesthesia; Anesthetics; Cerebral Cortex; Consciousness; Deep Brain Stimulation; Dose-Response | 2007 |
3 other studies available for sevoflurane and Parkinson Disease
| Article | Year |
|---|---|
Sevoflurane and Parkinson's Disease: Subthalamic Nucleus Neuronal Activity and Clinical Outcome of Deep Brain Stimulation.
Topics: Action Potentials; Adult; Aged; Anesthetics, Inhalation; Anesthetics, Local; Beta Rhythm; Cohort Stu | 2020 |
Desflurane and sevoflurane differentially affect activity of the subthalamic nucleus in Parkinson's disease.
Topics: Adult; Aged; Anesthetics, Inhalation; Brain Waves; Deep Brain Stimulation; Desflurane; Electroenceph | 2021 |
Effects of sevoflurane on leucine-rich repeat kinase 2-associated Drosophila model of Parkinson's disease.
Topics: Anesthetics, Inhalation; Animals; Animals, Genetically Modified; Disease Models, Animal; Drosophila | 2015 |