sevoflurane has been researched along with Neurodegenerative Diseases in 7 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To investigate mechanisms by which early life anesthesia exposure could induce long-term neuronal dysfunction, we exposed rats to 1 minimum alveolar concentration sevoflurane at 7 days of life." | 4.02 | Singular and short-term anesthesia exposure in the developing brain induces persistent neuronal changes consistent with chronic neurodegenerative disease. ( Hogarth, K; Maynes, JT; Stratmann, G; Vanama, RB, 2021) |
| "Sevoflurane treatment decreased microglia activation by suppressing NF-kB and MAPK signaling pathways." | 1.51 | Effect of sevoflurane treatment on microglia activation, NF-kB and MAPK activities. ( Shi, J; Yu, X; Zhang, F, 2019) |
| "Sevoflurane is a volatile anesthetic that is frequently used for pediatric anesthesia." | 1.43 | Neuroprotective effects of caffeic acid phenethyl ester against sevoflurane‑induced neuronal degeneration in the hippocampus of neonatal rats involve MAPK and PI3K/Akt signaling pathways. ( Han, YZ; Tang, ZJ; Wang, LY, 2016) |
| "Our asphyxia cardiac arrest (ACA) rat model is well established." | 1.43 | Anesthesia specific differences in a cardio-pulmonary resuscitation rat model; halothane versus sevoflurane. ( Ebmeyer, U; Esser, T; Keilhoff, G, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, D | 1 |
| Wang, H | 1 |
| Zhou, Y | 1 |
| Chen, Y | 1 |
| Chen, G | 1 |
| Yu, X | 1 |
| Zhang, F | 1 |
| Shi, J | 1 |
| Qu, Y | 1 |
| Li, H | 1 |
| Shi, C | 1 |
| Qian, M | 1 |
| Yang, N | 1 |
| Wang, L | 1 |
| Gao, X | 1 |
| Ni, C | 1 |
| Hogarth, K | 1 |
| Vanama, RB | 1 |
| Stratmann, G | 1 |
| Maynes, JT | 1 |
| Lee, JR | 1 |
| Lin, EP | 1 |
| Hofacer, RD | 1 |
| Upton, B | 1 |
| Lee, SY | 1 |
| Ewing, L | 1 |
| Joseph, B | 1 |
| Loepke, AW | 1 |
| Wang, LY | 1 |
| Tang, ZJ | 1 |
| Han, YZ | 1 |
| Esser, T | 1 |
| Keilhoff, G | 1 |
| Ebmeyer, U | 1 |
7 other studies available for sevoflurane and Neurodegenerative Diseases
| Article | Year |
|---|---|
Ac-YVAD-cmk ameliorated sevoflurane-induced cognitive dysfunction and revised mitophagy impairment.
Topics: Animals; Caspase 1; Cognitive Dysfunction; Inflammasomes; Interleukin-18; Mice; Mitophagy; Neurodege | 2023 |
Effect of sevoflurane treatment on microglia activation, NF-kB and MAPK activities.
Topics: Animals; Brain; Cell Movement; Cells, Cultured; Cytokines; Inflammation Mediators; Lipopolysaccharid | 2019 |
lncRNAs Are Involved in Sevoflurane Anesthesia-Related Brain Function Modulation through Affecting Mitochondrial Function and Aging Process.
Topics: Aging; Anesthesia; Anesthetics; Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Cognition Disorde | 2020 |
Singular and short-term anesthesia exposure in the developing brain induces persistent neuronal changes consistent with chronic neurodegenerative disease.
Topics: Anesthesia; Animals; Animals, Newborn; Apoptosis; Autophagosomes; Brain; Chronic Disease; Homeostasi | 2021 |
Alternative technique or mitigating strategy for sevoflurane-induced neurodegeneration: a randomized controlled dose-escalation study of dexmedetomidine in neonatal rats.
Topics: Anesthetics, Inhalation; Animals; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationshi | 2017 |
Neuroprotective effects of caffeic acid phenethyl ester against sevoflurane‑induced neuronal degeneration in the hippocampus of neonatal rats involve MAPK and PI3K/Akt signaling pathways.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Caffeic Acids; Female; Hippocampus; MAP Kinase S | 2016 |
Anesthesia specific differences in a cardio-pulmonary resuscitation rat model; halothane versus sevoflurane.
Topics: Anesthetics, Inhalation; Animals; Asphyxia; CA1 Region, Hippocampal; Cardiopulmonary Resuscitation; | 2016 |