sevoflurane has been researched along with Nerve Degeneration in 10 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "General anesthesia with sevoflurane is associated with an increased incidence of postoperative cognitive dysfunction." | 3.91 | Nerve growth factor metabolic dysfunction contributes to sevoflurane-induced cholinergic degeneration and cognitive impairments. ( Duan, L; Wang, Z; Xiong, L; Xu, W, 2019) |
| "In the present study, we tested the ability of sevoflurane to induce early and late preconditioning against ischemic neuronal injury using an in vivo model of global cerebral ischemia in the rat." | 3.73 | Sevoflurane-induced preconditioning protects against cerebral ischemic neuronal damage in rats. ( Akca, O; Kehl, F; Payne, RS; Roewer, N; Schurr, A, 2005) |
| "Isoflurane treatments significantly increased apoptosis indicated by the activation of caspase-3 and elevation of poly-(ADP-ribose) polymerase in different brain regions." | 1.36 | Isoflurane causes greater neurodegeneration than an equivalent exposure of sevoflurane in the developing brain of neonatal mice. ( Huang, B; Liang, G; Peng, J; Ward, C; Wei, H; Zhao, Y, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 8 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiong, L | 1 |
| Duan, L | 1 |
| Xu, W | 1 |
| Wang, Z | 1 |
| Goyagi, T | 1 |
| Zheng, SQ | 1 |
| An, LX | 1 |
| Cheng, X | 1 |
| Wang, YJ | 1 |
| Deng, B | 1 |
| Xu, H | 1 |
| Zhang, J | 1 |
| Wang, J | 1 |
| Han, LC | 1 |
| Li, LY | 1 |
| Wu, GL | 1 |
| Hou, YN | 1 |
| Guo, GZ | 1 |
| Wang, Q | 1 |
| Sang, HF | 1 |
| Xu, LX | 1 |
| Bercker, S | 1 |
| Bert, B | 1 |
| Bittigau, P | 1 |
| Felderhoff-Müser, U | 1 |
| Bührer, C | 1 |
| Ikonomidou, C | 1 |
| Weise, M | 1 |
| Kaisers, UX | 1 |
| Kerner, T | 1 |
| Liang, G | 1 |
| Ward, C | 1 |
| Peng, J | 1 |
| Zhao, Y | 1 |
| Huang, B | 1 |
| Wei, H | 1 |
| Piehl, E | 1 |
| Foley, L | 1 |
| Barron, M | 1 |
| D'Ardenne, C | 1 |
| Guillod, P | 1 |
| Wise-Faberowski, L | 1 |
| Cross, DA | 1 |
| Fang, F | 1 |
| Xue, Z | 1 |
| Cang, J | 1 |
| Payne, RS | 1 |
| Akca, O | 1 |
| Roewer, N | 1 |
| Schurr, A | 1 |
| Kehl, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Sevoflurane-induced Postconditioning on the Incidence of Postoperative Cerebral Hyperperfusion Syndrome After Revascularization Surgery in Adult Patients With Moyamoya Disease[NCT02510586] | 152 participants (Anticipated) | Interventional | 2015-08-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 other studies available for sevoflurane and Nerve Degeneration
| Article | Year |
|---|---|
Nerve growth factor metabolic dysfunction contributes to sevoflurane-induced cholinergic degeneration and cognitive impairments.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Basal Forebrain; Choline O-Acetyltransferase; Choliner | 2019 |
Dexmedetomidine reduced sevoflurane-induced neurodegeneration and long-term memory deficits in neonatal rats.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cognition; Conditioning, Classical; Dexmedetomid | 2019 |
Sevoflurane causes neuronal apoptosis and adaptability changes of neonatal rats.
Topics: Adaptation, Physiological; Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Behavior, | 2013 |
Neuroprotective effects of sevoflurane against electromagnetic pulse-induced brain injury through inhibition of neuronal oxidative stress and apoptosis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Behavior, Animal; Brain Injuries; Caspase 3; Cell Su | 2014 |
Neurodegeneration in newborn rats following propofol and sevoflurane anesthesia.
Topics: Analysis of Variance; Anesthetics; Animals; Animals, Newborn; Blood Gas Analysis; Cues; Dose-Respons | 2009 |
Isoflurane causes greater neurodegeneration than an equivalent exposure of sevoflurane in the developing brain of neonatal mice.
Topics: Age Factors; Animals; Animals, Newborn; Biomarkers; Brain; Female; Isoflurane; Male; Methyl Ethers; | 2010 |
The effect of sevoflurane on neuronal degeneration and GABAA subunit composition in a developing rat model of organotypic hippocampal slice cultures.
Topics: Anesthetics, Inhalation; Animals; Blotting, Western; CA1 Region, Hippocampal; Caspase 3; Cell Death; | 2010 |
Multiples of minimal alveolar concentration of volatile agents are not necessarily equipotent.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Brain; Dose-Response Relationship, Drug; Isoflur | 2011 |
Sevoflurane exposure in 7-day-old rats affects neurogenesis, neurodegeneration and neurocognitive function.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cell Proliferation; Cognition; Male; Maze Learni | 2012 |
Sevoflurane-induced preconditioning protects against cerebral ischemic neuronal damage in rats.
Topics: Action Potentials; Anesthetics, Inhalation; Animals; Brain Ischemia; Cell Death; Disease Models, Ani | 2005 |