sevoflurane has been researched along with Myocardial Ischemia in 53 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| " We hypothesized that sevoflurane compared with propofol reduces the incidence of myocardial ischemia in patients undergoing major noncardiac surgery." | 9.16 | Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery. ( Bolliger, D; Fassl, J; Filipovic, M; Kasper, J; Lurati Buse, GA; Schumacher, P; Schuman, RM; Seeberger, E; Seeberger, MD; Studer, W, 2012) |
| "Sevoflurane is associated with less tachycardia and coronary vasodilation than isoflurane and thus might be associated with less myocardial ischemia." | 9.08 | Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group. ( Ebert, TJ; Kharasch, ED; Muzi, M; Rooke, GA; Shroff, A, 1997) |
| "Sevoflurane (Sevo) prevents hypoxia/reoxygenation (H/R)-induced cardiomyocytes apoptosis." | 8.02 | Sevoflurane inhibits the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes via regulating miR-27a-3p-mediated autophagy. ( Chen, S; Hu, Y; Zhan, B; Zhang, Q; Zhang, Y, 2021) |
| "The inhaled sevoflurane (sevo) is known to protect against myocardial ischemia/reperfusion (I/R) injury (MIRI), in which the functions of microRNAs (miRNAs) have been uncovered." | 7.96 | Sevoflurane up-regulates microRNA-204 to ameliorate myocardial ischemia/reperfusion injury in mice by suppressing Cotl1. ( Bai, TZ; Chen, XX; Li, ZF; Tan, DX; Zhang, J, 2020) |
| "The reduction in hypothermia and ischaemia-induced reperfusion arrhythmias by the addition of sevoflurane to HTK solution may be related to the phosphorylation of Cx43 at serine 368." | 7.91 | Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368. ( Gao, H; Gao, J; Li, WC; Wang, ZJ, 2019) |
| "BACKGROUND The aim of this study was to investigate the effects of sevoflurane (SEV) on myocardial ischemia/reperfusion (I/R) injury in rats and its mechanism." | 7.91 | Effects of Sevoflurane Pretreatment on Myocardial Ischemia-Reperfusion Injury Through the Akt/Hypoxia-Inducible Factor 1-alpha (HIF-1α)/Vascular Endothelial Growth Factor (VEGF) Signaling Pathway. ( Che, X; Dong, J; Xu, M; Zhang, W, 2019) |
| "Inhalation anesthesia with sevoflurane seems superior to intravenous anesthesia with propofol in acute right ventricular ischemic dysfunction." | 7.83 | Sevoflurane anesthesia during acute right ventricular ischemia in pigs preserves cardiac function better than propofol anesthesia. ( Algotsson, L; Haraldsen, P; Ingemansson, R; Lindstedt, S; Metzsch, C, 2016) |
| "Twenty Wistar rats were allocated in three groups: control (CON, n=10), myocardial infarction with sevoflurane (SEV, n=5) and infarcted without sevoflurane (INF, n=5)." | 7.83 | Sevoflurane preconditioning during myocardial ischemia-reperfusion reduces infarct size and preserves autonomic control of circulation in rats. ( Auler, JO; Irigoyen, MC; Mostarda, CT; Otsuki, DA; Pasqualin, RC; Sirvente, R; Souza, LE; Torres, ML; Vane, MF, 2016) |
| "The authors' results suggest that propofol preserves connexin 43 phosphorylation during acute myocardial ischemia, as compared with sevoflurane, and this might protect the heart from serious ventricular arrhythmias during acute coronary occlusion." | 7.75 | Differential effects of propofol and sevoflurane on ischemia-induced ventricular arrhythmias and phosphorylated connexin 43 protein in rats. ( Hirata, N; Kamada, N; Kanaya, N; Kimura, S; Namiki, A, 2009) |
| "Neither halothane nor sevoflurane protected the heart against the effects of acute and severe regional myocardial ischemia." | 7.70 | Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane. ( Coetzee, A; Coetzee, J; Conradie, S, 1999) |
| "Sevoflurane was found to elevate miR-203, and miR-203, in turn, could target and reduce DCX expression." | 5.56 | MicroRNA-203-mediated inhibition of doublecortin underpins cardioprotection conferred by sevoflurane in rats after myocardial ischaemia-reperfusion injury. ( Liu, J; Peng, H; Tan, J; Wu, Z; Yuan, W; Zhang, W, 2020) |
| " We hypothesized that sevoflurane compared with propofol reduces the incidence of myocardial ischemia in patients undergoing major noncardiac surgery." | 5.16 | Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery. ( Bolliger, D; Fassl, J; Filipovic, M; Kasper, J; Lurati Buse, GA; Schumacher, P; Schuman, RM; Seeberger, E; Seeberger, MD; Studer, W, 2012) |
| "Sevoflurane is associated with less tachycardia and coronary vasodilation than isoflurane and thus might be associated with less myocardial ischemia." | 5.08 | Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group. ( Ebert, TJ; Kharasch, ED; Muzi, M; Rooke, GA; Shroff, A, 1997) |
| "Sevoflurane (Sevo) prevents hypoxia/reoxygenation (H/R)-induced cardiomyocytes apoptosis." | 4.02 | Sevoflurane inhibits the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes via regulating miR-27a-3p-mediated autophagy. ( Chen, S; Hu, Y; Zhan, B; Zhang, Q; Zhang, Y, 2021) |
| "The inhaled sevoflurane (sevo) is known to protect against myocardial ischemia/reperfusion (I/R) injury (MIRI), in which the functions of microRNAs (miRNAs) have been uncovered." | 3.96 | Sevoflurane up-regulates microRNA-204 to ameliorate myocardial ischemia/reperfusion injury in mice by suppressing Cotl1. ( Bai, TZ; Chen, XX; Li, ZF; Tan, DX; Zhang, J, 2020) |
| "The reduction in hypothermia and ischaemia-induced reperfusion arrhythmias by the addition of sevoflurane to HTK solution may be related to the phosphorylation of Cx43 at serine 368." | 3.91 | Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368. ( Gao, H; Gao, J; Li, WC; Wang, ZJ, 2019) |
| "BACKGROUND The aim of this study was to investigate the effects of sevoflurane (SEV) on myocardial ischemia/reperfusion (I/R) injury in rats and its mechanism." | 3.91 | Effects of Sevoflurane Pretreatment on Myocardial Ischemia-Reperfusion Injury Through the Akt/Hypoxia-Inducible Factor 1-alpha (HIF-1α)/Vascular Endothelial Growth Factor (VEGF) Signaling Pathway. ( Che, X; Dong, J; Xu, M; Zhang, W, 2019) |
| "Inhalation anesthesia with sevoflurane seems superior to intravenous anesthesia with propofol in acute right ventricular ischemic dysfunction." | 3.83 | Sevoflurane anesthesia during acute right ventricular ischemia in pigs preserves cardiac function better than propofol anesthesia. ( Algotsson, L; Haraldsen, P; Ingemansson, R; Lindstedt, S; Metzsch, C, 2016) |
| "Twenty Wistar rats were allocated in three groups: control (CON, n=10), myocardial infarction with sevoflurane (SEV, n=5) and infarcted without sevoflurane (INF, n=5)." | 3.83 | Sevoflurane preconditioning during myocardial ischemia-reperfusion reduces infarct size and preserves autonomic control of circulation in rats. ( Auler, JO; Irigoyen, MC; Mostarda, CT; Otsuki, DA; Pasqualin, RC; Sirvente, R; Souza, LE; Torres, ML; Vane, MF, 2016) |
| "The authors' results suggest that propofol preserves connexin 43 phosphorylation during acute myocardial ischemia, as compared with sevoflurane, and this might protect the heart from serious ventricular arrhythmias during acute coronary occlusion." | 3.75 | Differential effects of propofol and sevoflurane on ischemia-induced ventricular arrhythmias and phosphorylated connexin 43 protein in rats. ( Hirata, N; Kamada, N; Kanaya, N; Kimura, S; Namiki, A, 2009) |
| "Sevoflurane preconditioning (SPC) in adult hearts reduces myocardial ischemia/reperfusion (I/R) injury, an effect that may be mediated by reductions in intracellular Ca(2+) ([Ca(2+)](i)) and/or mitochondrial Ca(2+) ([Ca(2+)](m)) accumulation during ischemia and reperfusion." | 3.73 | Sevoflurane preconditioning limits intracellular/mitochondrial Ca2+ in ischemic newborn myocardium. ( Eaton, M; Liu, H; Schaefer, S; Wang, L, 2005) |
| "Neither halothane nor sevoflurane protected the heart against the effects of acute and severe regional myocardial ischemia." | 3.70 | Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane. ( Coetzee, A; Coetzee, J; Conradie, S, 1999) |
| "Eighty children scheduled for ventricular septal defect closure under cardioplegic arrest were assigned to preconditioning for five minutes after commencement of cardiopulmonary bypass (CPB) with one minimum alveolar concentration (MAC) of one of the following agents: isoflurane, sevoflurane, desflurane, or placebo (oxygen-air mixture)." | 2.78 | Comparison of cardioprotective effects of volatile anesthetics in children undergoing ventricular septal defect closure. ( Chauhan, S; Jain, G; Kiran, U; Makhija, N; Singh, P; Talwar, S, 2013) |
| "Treatment with sevoflurane before coronary occlusion seem effective in reducing functional myocardial impairment due to ischemia." | 2.71 | [Cardiac protection is a clinical evidence]. ( Baldassarri, R; Cariello, C; Doroni, L; Guarracino, F; Vullo, C, 2004) |
| "Sevoflurane was found to elevate miR-203, and miR-203, in turn, could target and reduce DCX expression." | 1.56 | MicroRNA-203-mediated inhibition of doublecortin underpins cardioprotection conferred by sevoflurane in rats after myocardial ischaemia-reperfusion injury. ( Liu, J; Peng, H; Tan, J; Wu, Z; Yuan, W; Zhang, W, 2020) |
| "Sevoflurane was washed out for 30 min, and 5-HD for 15 min, before 30-min ischemia and 120-min reperfusion." | 1.32 | Preconditioning with sevoflurane reduces changes in nicotinamide adenine dinucleotide during ischemia-reperfusion in isolated hearts: reversal by 5-hydroxydecanoic acid. ( Camara, AK; Chen, Q; Eells, JT; Novalija, E; Riess, ML; Stowe, DF, 2003) |
| "Sevoflurane was washed out for 30 min and 5-HD for 15 min before 30 min of global ischemia and 120 min of reperfusion." | 1.31 | Anesthetic preconditioning attenuates mitochondrial Ca2+ overload during ischemia in Guinea pig intact hearts: reversal by 5-hydroxydecanoic acid. ( Camara, AK; Chen, Q; Novalija, E; Rhodes, SS; Riess, ML; Stowe, DF, 2002) |
| "Ca(2+) loading occurs during myocardial reperfusion injury." | 1.31 | Sevoflurane before or after ischemia improves contractile and metabolic function while reducing myoplasmic Ca(2+) loading in intact hearts. ( An, J; Novalija, E; Stowe, DF; Varadarajan, SG, 2002) |
| "Sevoflurane has been reported to attenuate ischaemia-induced changes of myocardial metabolism, but the mechanism is still unclear." | 1.30 | Sevoflurane preserves endocardial blood flow during coronary ligation in dogs: comparison with adenosine. ( Abiko, Y; Ichihara, K; Ogawa, H; Takahata, O, 1998) |
| "Sevoflurane has been reported to generate oxygen free radicals." | 1.30 | Effects of sevoflurane and isoflurane on free radical formation in the post-ischaemic reperfused heart. ( Ikeya, K; Kashimoto, S; Kumazawa, T; Kume, M, 1998) |
| "Hydroxyl radicals were identified by their reaction with salicylic acid to yield dihydroxybenzoic acids (DHBAs)." | 1.30 | Hydroxyl radical formation during inhalation anesthesia in the reperfused working rat heart. ( Kashimoto, S; Kumazawa, T; Nakamura, T; Oguchi, T, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (24.53) | 18.2507 |
| 2000's | 21 (39.62) | 29.6817 |
| 2010's | 14 (26.42) | 24.3611 |
| 2020's | 5 (9.43) | 2.80 |
| Authors | Studies |
|---|---|
| Xie, D | 1 |
| Zhao, J | 1 |
| Guo, R | 1 |
| Jiao, L | 1 |
| Zhang, Y | 2 |
| Lau, WB | 1 |
| Lopez, B | 1 |
| Christopher, T | 1 |
| Gao, E | 1 |
| Cao, J | 1 |
| Ma, X | 1 |
| Wang, Y | 1 |
| Hong, L | 1 |
| Sun, Y | 1 |
| An, JZ | 1 |
| Wang, C | 1 |
| Qiao, SG | 1 |
| Tan, DX | 1 |
| Chen, XX | 1 |
| Bai, TZ | 1 |
| Zhang, J | 1 |
| Li, ZF | 1 |
| Tan, J | 1 |
| Wu, Z | 1 |
| Liu, J | 1 |
| Zhang, W | 2 |
| Yuan, W | 1 |
| Peng, H | 1 |
| Zhan, B | 1 |
| Hu, Y | 1 |
| Chen, S | 1 |
| Zhang, Q | 1 |
| Guerrero-Orriach, JL | 1 |
| Escalona Belmonte, JJ | 1 |
| Ramirez Fernandez, A | 1 |
| Ramirez Aliaga, M | 1 |
| Rubio Navarro, M | 1 |
| Cruz Mañas, J | 1 |
| Behmenburg, F | 1 |
| Boekholt, Y | 1 |
| van Caster, P | 1 |
| Dorsch, M | 1 |
| Heinen, A | 1 |
| Hollmann, MW | 1 |
| Huhn, R | 1 |
| Li, WC | 1 |
| Gao, H | 1 |
| Gao, J | 1 |
| Wang, ZJ | 1 |
| Dong, J | 1 |
| Xu, M | 1 |
| Che, X | 1 |
| Singh, P | 1 |
| Chauhan, S | 1 |
| Jain, G | 1 |
| Talwar, S | 1 |
| Makhija, N | 1 |
| Kiran, U | 1 |
| Mellidis, K | 1 |
| Ordodi, V | 1 |
| Galatou, E | 1 |
| Săndesc, D | 1 |
| Bubenek, S | 1 |
| Duicu, O | 1 |
| Muntean, D | 1 |
| Lazou, A | 1 |
| Kopić, J | 1 |
| Jiang, JJ | 1 |
| Li, C | 1 |
| Li, H | 2 |
| Zhang, L | 1 |
| Lin, ZH | 1 |
| Fu, BJ | 1 |
| Zeng, YM | 1 |
| Haraldsen, P | 1 |
| Metzsch, C | 1 |
| Lindstedt, S | 1 |
| Algotsson, L | 1 |
| Ingemansson, R | 1 |
| Gao, S | 1 |
| Yang, Z | 1 |
| Shi, R | 1 |
| Xu, D | 1 |
| Xia, Z | 1 |
| Wu, QP | 1 |
| Yao, S | 1 |
| Wang, T | 1 |
| Yuan, S | 1 |
| Pasqualin, RC | 1 |
| Mostarda, CT | 1 |
| Souza, LE | 1 |
| Vane, MF | 1 |
| Sirvente, R | 1 |
| Otsuki, DA | 1 |
| Torres, ML | 1 |
| Irigoyen, MC | 1 |
| Auler, JO | 1 |
| Landoni, G | 1 |
| Zangrillo, A | 1 |
| Fochi, O | 1 |
| Maj, G | 1 |
| Scandroglio, AM | 1 |
| Morelli, A | 1 |
| Tritapepe, L | 1 |
| Montorfano, M | 1 |
| Colombo, A | 1 |
| Hirata, N | 1 |
| Kanaya, N | 1 |
| Kamada, N | 1 |
| Kimura, S | 1 |
| Namiki, A | 1 |
| Yao, YT | 1 |
| Li, LH | 1 |
| Sanders, RD | 1 |
| Maze, M | 1 |
| Lurati Buse, GA | 1 |
| Schumacher, P | 1 |
| Seeberger, E | 1 |
| Studer, W | 1 |
| Schuman, RM | 1 |
| Fassl, J | 1 |
| Kasper, J | 1 |
| Filipovic, M | 1 |
| Bolliger, D | 1 |
| Seeberger, MD | 1 |
| Kersten, JR | 2 |
| Riess, ML | 5 |
| Camara, AK | 5 |
| Novalija, E | 7 |
| Chen, Q | 4 |
| Rhodes, SS | 2 |
| Stowe, DF | 7 |
| Eells, JT | 1 |
| Kevin, LG | 1 |
| Katz, P | 1 |
| Tang, Y | 1 |
| Wang, QY | 1 |
| de Ruijter, W | 2 |
| Musters, RJP | 1 |
| Boer, C | 3 |
| Stienen, GJM | 1 |
| Simonides, WS | 1 |
| de Lange, JJ | 3 |
| Zhong, C | 1 |
| Zhou, Y | 1 |
| Liu, H | 4 |
| Guarracino, F | 1 |
| Doroni, L | 1 |
| Cariello, C | 1 |
| Baldassarri, R | 1 |
| Vullo, C | 1 |
| Wang, L | 1 |
| Eaton, M | 1 |
| Schaefer, S | 1 |
| Lutz, M | 1 |
| Bouwman, RA | 2 |
| Salic, K | 1 |
| Padding, FG | 1 |
| Eringa, EC | 1 |
| van Beek-Harmsen, BJ | 2 |
| Matsuda, T | 1 |
| Baba, A | 1 |
| Musters, RJ | 2 |
| Paulus, WJ | 1 |
| van't Hof, FN | 1 |
| Yu, CH | 1 |
| Beattie, WS | 1 |
| Deyhimy, DI | 1 |
| Fleming, NW | 1 |
| Brodkin, IG | 1 |
| Pagel, PS | 2 |
| Takahata, O | 2 |
| Ichihara, K | 2 |
| Ogawa, H | 2 |
| Oguchi, T | 3 |
| Kashimoto, S | 4 |
| Yamaguchi, T | 2 |
| Nakamura, T | 3 |
| Kumazawa, T | 4 |
| Brayer, AP | 1 |
| Tessmer, JP | 1 |
| Warltier, DC | 1 |
| Kim, Y | 1 |
| Shibutani, T | 1 |
| Hirota, Y | 1 |
| Hori, T | 1 |
| Matsuura, H | 1 |
| Searle, NR | 1 |
| Martineau, RJ | 1 |
| Conzen, P | 1 |
| al-Hasani, A | 1 |
| Mark, L | 1 |
| Ebert, T | 1 |
| Muzi, M | 2 |
| Hodgins, LR | 1 |
| Ebert, TJ | 1 |
| Kharasch, ED | 1 |
| Rooke, GA | 1 |
| Shroff, A | 1 |
| Mathur, S | 1 |
| Karmazyn, M | 1 |
| Abiko, Y | 1 |
| Kume, M | 1 |
| Ikeya, K | 1 |
| Conradie, S | 1 |
| Coetzee, A | 1 |
| Coetzee, J | 1 |
| Heindl, B | 1 |
| Becker, BF | 1 |
| Varadarajan, SG | 2 |
| An, J | 2 |
| Hogg, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sevoflurane and Cardiac Protection in High Risk Patients Undergoing Cardiac Surgery. A Randomized Controlled Study.[NCT00821262] | Phase 4 | 200 participants (Actual) | Interventional | 2008-09-30 | Completed | ||
| Effect of Sevoflurane on CKMB Release After PCI With Drug-eluting Stents: a Randomised Trial[NCT02671084] | Phase 4 | 701 participants (Actual) | Interventional | 2016-02-29 | Terminated (stopped due to interim analysis suggests futility) | ||
| Multi-Center Trial on the Effect of Anesthetics on Morbidity and Mortality in Patients Undergoing Major Non-cardiac Surgery[NCT00286585] | Phase 4 | 385 participants (Actual) | Interventional | 2006-02-28 | Completed | ||
| Perioperative Multimodal General Anesthesia Focusing on Specific CNS Targets in Patients Undergoing Cardiac Surgeries[NCT04016740] | Early Phase 1 | 22 participants (Actual) | Interventional | 2019-08-20 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for sevoflurane and Myocardial Ischemia
| Article | Year |
|---|---|
Cardioprotection with halogenated gases: how does it occur?
Topics: Animals; Cardiotonic Agents; Gases; Humans; Methyl Ethers; Myocardial Ischemia; Propofol; Sevofluran | 2017 |
Sevoflurane versus propofol for myocardial protection in patients undergoing coronary artery bypass grafting surgery: a meta-analysis of randomized controlled trials.
Topics: Adult; Anesthetics; Cardiotonic Agents; Coronary Artery Bypass; Humans; Methyl Ethers; Myocardial Is | 2009 |
The effects of volatile anesthetics on cardiac ischemic complications and mortality in CABG: a meta-analysis.
Topics: Anesthetics, Inhalation; Coronary Artery Bypass; Creatine Kinase, MB Form; Desflurane; Electrocardio | 2006 |
7 trials available for sevoflurane and Myocardial Ischemia
| Article | Year |
|---|---|
Comparison of cardioprotective effects of volatile anesthetics in children undergoing ventricular septal defect closure.
Topics: Anesthetics, Inhalation; Cardiopulmonary Bypass; Cardiotonic Agents; Creatine Kinase, MB Form; Desfl | 2013 |
Volatile anaesthetics and cardiac protection in abdominal surgery.
Topics: Abdomen; Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Cardiotonic Agents; Colectomy; Col | 2015 |
Cardiac protection with volatile anesthetics in stenting procedures.
Topics: Aged; Anesthetics, Inhalation; Cardiotonic Agents; Coronary Artery Bypass; Humans; Methyl Ethers; Mi | 2008 |
Cardiac protection with volatile anesthetics in stenting procedures.
Topics: Aged; Anesthetics, Inhalation; Cardiotonic Agents; Coronary Artery Bypass; Humans; Methyl Ethers; Mi | 2008 |
Cardiac protection with volatile anesthetics in stenting procedures.
Topics: Aged; Anesthetics, Inhalation; Cardiotonic Agents; Coronary Artery Bypass; Humans; Methyl Ethers; Mi | 2008 |
Cardiac protection with volatile anesthetics in stenting procedures.
Topics: Aged; Anesthetics, Inhalation; Cardiotonic Agents; Coronary Artery Bypass; Humans; Methyl Ethers; Mi | 2008 |
Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery.
Topics: Aged; Aged, 80 and over; Anesthetics; Female; Follow-Up Studies; Humans; Intraoperative Complication | 2012 |
Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery.
Topics: Aged; Aged, 80 and over; Anesthetics; Female; Follow-Up Studies; Humans; Intraoperative Complication | 2012 |
Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery.
Topics: Aged; Aged, 80 and over; Anesthetics; Female; Follow-Up Studies; Humans; Intraoperative Complication | 2012 |
Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery.
Topics: Aged; Aged, 80 and over; Anesthetics; Female; Follow-Up Studies; Humans; Intraoperative Complication | 2012 |
[Cardiac protection is a clinical evidence].
Topics: Aged; Anesthetics, Inhalation; Coronary Disease; Female; Humans; Male; Methyl Ethers; Myocardial Isc | 2004 |
Comparison of sevoflurane/fentanyl and isoflurane/fentanyl during elective coronary artery bypass surgery. Sevoflurane Venture Group.
Topics: Aged; Anesthetics, Inhalation; Coronary Artery Bypass; Electrocardiography, Ambulatory; Ethers; Fema | 1996 |
Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Coronary Disease; Ethers; Female; Heart Dis | 1997 |
43 other studies available for sevoflurane and Myocardial Ischemia
| Article | Year |
|---|---|
Sevoflurane Pre-conditioning Ameliorates Diabetic Myocardial Ischemia/Reperfusion Injury Via Differential Regulation of p38 and ERK.
Topics: Animals; Cardiotonic Agents; Diabetes Mellitus, Experimental; Diet, High-Fat; Extracellular Signal-R | 2020 |
Sevoflurane Preconditioning Confers Delayed Cardioprotection by Upregulating AMP-Activated Protein Kinase Levels to Restore Autophagic Flux in Ischemia-Reperfusion Rat Hearts.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Cardiotonic Agents; China; Ischemic Preconditioni | 2020 |
Sevoflurane up-regulates microRNA-204 to ameliorate myocardial ischemia/reperfusion injury in mice by suppressing Cotl1.
Topics: Anesthetics, Inhalation; Animals; Disease Progression; Hemodynamics; Male; Mice; Mice, Inbred C57BL; | 2020 |
MicroRNA-203-mediated inhibition of doublecortin underpins cardioprotection conferred by sevoflurane in rats after myocardial ischaemia-reperfusion injury.
Topics: Animals; Antagomirs; Cardiotonic Agents; Disease Models, Animal; Doublecortin Domain Proteins; Doubl | 2020 |
Sevoflurane inhibits the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes via regulating miR-27a-3p-mediated autophagy.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Autophagy; Cell Line; Cell Survival; Down-Regulation; H | 2021 |
Extended Second Window of Protection of Sevoflurane-induced Preconditioning.
Topics: Animals; Ischemic Preconditioning, Myocardial; Male; Methyl Ethers; Myocardial Infarction; Myocardia | 2017 |
Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Connexin 43; Disease Models, Animal; Gap Junc | 2019 |
Effects of Sevoflurane Pretreatment on Myocardial Ischemia-Reperfusion Injury Through the Akt/Hypoxia-Inducible Factor 1-alpha (HIF-1α)/Vascular Endothelial Growth Factor (VEGF) Signaling Pathway.
Topics: Animals; Apoptosis; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Myocardial Ischemia; Myocardial | 2019 |
Activation of prosurvival signaling pathways during the memory phase of volatile anesthetic preconditioning in human myocardium: a pilot study.
Topics: Aged; Anesthetics, General; Anesthetics, Inhalation; Extracellular Signal-Regulated MAP Kinases; Fem | 2014 |
Sevoflurane postconditioning affects post-ischaemic myocardial mitochondrial ATP-sensitive potassium channel function and apoptosis in ageing rats.
Topics: Aging; Animals; Apoptosis; bcl-2-Associated X Protein; Coronary Circulation; Decanoic Acids; Hemodyn | 2016 |
Sevoflurane anesthesia during acute right ventricular ischemia in pigs preserves cardiac function better than propofol anesthesia.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cardiac Output; Coronary Cir | 2016 |
Diabetes blocks the cardioprotective effects of sevoflurane postconditioning by impairing Nrf2/Brg1/HO-1 signaling.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Line; Diabetes Mellitus, Experimental; DNA Helicases; H | 2016 |
Sevoflurane preconditioning during myocardial ischemia-reperfusion reduces infarct size and preserves autonomic control of circulation in rats.
Topics: Anesthetics, Inhalation; Animals; Autonomic Nervous System; Blood Pressure; Echocardiography; Heart | 2016 |
Differential effects of propofol and sevoflurane on ischemia-induced ventricular arrhythmias and phosphorylated connexin 43 protein in rats.
Topics: Animals; Arrhythmias, Cardiac; Connexin 43; Heart Rate; Male; Methyl Ethers; Myocardial Ischemia; Ph | 2009 |
Neuroinflammation and postoperative cognitive dysfunction: can anaesthesia be therapeutic?
Topics: Aged; Anesthesia; Anesthetics, Inhalation; Animals; Cognition Disorders; Coronary Vessels; Humans; I | 2010 |
A recipe for perioperative cardioprotection: what matters most? The ingredients or the chef?
Topics: Female; Humans; Intraoperative Complications; Male; Methyl Ethers; Myocardial Ischemia; Perioperativ | 2012 |
Anesthetic preconditioning attenuates mitochondrial Ca2+ overload during ischemia in Guinea pig intact hearts: reversal by 5-hydroxydecanoic acid.
Topics: Anesthetics; Animals; Calcium; Decanoic Acids; Guinea Pigs; Heart Rate; Hydroxy Acids; Ischemic Prec | 2002 |
Preconditioning with sevoflurane reduces changes in nicotinamide adenine dinucleotide during ischemia-reperfusion in isolated hearts: reversal by 5-hydroxydecanoic acid.
Topics: Anesthetics, Inhalation; Animals; ATP-Binding Cassette Transporters; Blood Pressure; Coronary Circul | 2003 |
Anesthetic preconditioning: effects on latency to ischemic injury in isolated hearts.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Blood Pressure; Coronary Circulation; Guinea Pigs; In | 2003 |
[Effects of sevoflurane-induced and anoxia-induced preconditioning on HSP70 expression in neonatal rat cardiomyocytes].
Topics: Animals; Animals, Newborn; Cells, Cultured; HSP70 Heat-Shock Proteins; Ischemic Preconditioning, Myo | 2003 |
The cardioprotective effect of sevoflurane depends on protein kinase C activation, opening of mitochondrial K(+)(ATP) channels, and the production of reactive oxygen species.
Topics: Anesthetics, Inhalation; Animals; ATP-Binding Cassette Transporters; Enzyme Activation; Enzyme Inhib | 2003 |
Nuclear factor kappaB and anesthetic preconditioning during myocardial ischemia-reperfusion.
Topics: Anesthetics, Inhalation; Animals; Blotting, Western; Cell Nucleus; Creatine Kinase; DNA; Hemodynamic | 2004 |
Sevoflurane preconditioning limits intracellular/mitochondrial Ca2+ in ischemic newborn myocardium.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Calcium; Ischemic Preconditioning, Myocardial; M | 2005 |
Inhaled sevoflurane produces better delayed myocardial protection at 48 versus 24 hours after exposure.
Topics: Administration, Inhalation; Animals; Male; Methyl Ethers; Myocardial Ischemia; Myocardium; Rats; Rat | 2006 |
Cardioprotection via activation of protein kinase C-delta depends on modulation of the reverse mode of the Na+/Ca2+ exchanger.
Topics: Anesthetics, Inhalation; Aniline Compounds; Animals; Calcium Signaling; Cardiotonic Agents; Enzyme A | 2006 |
The mechanism of sevoflurane-induced cardioprotection is independent of the applied ischaemic stimulus in rat trabeculae.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Enzyme Activation; Heart Ventricles; Hypoxia; Ischemic | 2006 |
Anesthetic preconditioning combined with postconditioning offers no additional benefit over preconditioning or postconditioning alone.
Topics: Anesthetics, Inhalation; Animals; Heart Rate; Ischemic Preconditioning, Myocardial; Male; Methyl Eth | 2007 |
When lack of addition really does add up.
Topics: Animals; Drug Dosage Calculations; Methyl Ethers; Myocardial Ischemia; Rats; Sevoflurane | 2007 |
Effects of sevoflurane on ischaemic myocardium in dogs.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Blood Pressure; Dog | 1995 |
Comparative effects of halothane, enflurane, isoflurane and sevoflurane on function and metabolism in the ischaemic rat heart.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Cardiac Output; Coronary Circulation; Enfl | 1995 |
Perfusion of ischemic myocardium during anesthesia with sevoflurane.
Topics: Anesthesia, Endotracheal; Anesthetics; Animals; Blood Pressure; Coronary Disease; Dogs; Dose-Respons | 1994 |
Is pentobarbital appropriate for basal anesthesia in the working rat heart model?
Topics: Administration, Inhalation; Anesthesia; Animals; Ethers; Heart; Hemodynamics; Injections, Intraperit | 1993 |
Giant negative T waves after maxillofacial surgery.
Topics: Anesthesia, Dental; Anesthesia, General; Arrhythmias, Cardiac; Electrocardiography; Ethers; Heart Co | 1992 |
Interaction between anesthetics and the sodium-hydrogen exchange inhibitor HOE 642 (cariporide) in ischemic and reperfused rat hearts.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Drug Interactions; Ethers; Guanidines; H | 1997 |
Sevoflurane preserves endocardial blood flow during coronary ligation in dogs: comparison with adenosine.
Topics: Adenosine; Anesthetics, Inhalation; Animals; Coronary Circulation; Dogs; Female; Hemodynamics; Male; | 1998 |
Effects of sevoflurane and isoflurane on free radical formation in the post-ischaemic reperfused heart.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Cardiac Output; Chromatography, High Pressure Liqu | 1998 |
Prior preconditioning by ischemia or sevoflurane improves cardiac work per oxygen use in isolated guinea pig hearts after global ischemia.
Topics: Adenosine; Analysis of Variance; Animals; Guinea Pigs; Heart; Heart Arrest, Induced; In Vitro Techni | 1998 |
Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane.
Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Fentanyl; Halotha | 1999 |
Hydroxyl radical formation during inhalation anesthesia in the reperfused working rat heart.
Topics: Anesthetics, Inhalation; Animals; Halothane; Hydroxyl Radical; Isoflurane; Male; Methyl Ethers; Myoc | 1999 |
Sevoflurane and isoflurane do not enhance the pre- and postischemic eicosanoid production in guinea pig hearts.
Topics: Anesthetics, Inhalation; Animals; Coronary Circulation; Dinoprost; Eicosanoids; Guinea Pigs; Hemodyn | 2000 |
Sevoflurane before or after ischemia improves contractile and metabolic function while reducing myoplasmic Ca(2+) loading in intact hearts.
Topics: Anesthetics, Inhalation; Animals; Calcium; Guinea Pigs; Halothane; In Vitro Techniques; Ischemic Pre | 2002 |
Anesthetic preconditioning: triggering role of reactive oxygen and nitrogen species in isolated hearts.
Topics: Anesthetics; Animals; Coronary Circulation; Enzyme Inhibitors; Guinea Pigs; Heart; In Vitro Techniqu | 2002 |
Altered NADH and improved function by anesthetic and ischemic preconditioning in guinea pig intact hearts.
Topics: Anesthetics; Animals; Creatine Kinase; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Heart V | 2002 |