Page last updated: 2024-11-04

sevoflurane and Myasthenia Gravis

sevoflurane has been researched along with Myasthenia Gravis in 19 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

Research Excerpts

ExcerptRelevanceReference
"Little information is available regarding the neuromuscular effects of sevoflurane in patients with myasthenia gravis (MG)."7.74Neuromuscular effects of sevoflurane in myasthenia gravis patients. ( Hamada, T; Higa, K; Nitahara, K; Shono, S; Sugi, Y, 2007)
"5% lidocaine with 1:200,000 epinephrine and inhaled anesthesia using nitrous oxide, oxygen and sevoflurane were performed in two patients, (40 and 22 yr-old females) with myasthenia gravis."7.68[Continuous thoracic epidural blockade in combination with general anesthesia with nitrous oxide, oxygen, and sevoflurane in two patients with myasthenia gravis]. ( Fujimura, N; Fujita, S; Kawamata, M; Miyabe, M; Nakae, Y; Namiki, A; Sonoda, H; Sumita, S, 1993)
"Myasthenia gravis is characterized by weakness and easy fatiguability of voluntary muscles."5.34Myasthenia gravis and sevoflurane--a case report. ( Dikmen, B; Erk, G; Karabeyoglu, I, 2007)
"Myasthenia gravis is a challenging situation for anaesthesiologists due to its neuromuscular involvement."5.31Sevoflurane as a sole anaesthetic for thymectomy in myasthenia gravis. ( Choudhury, M; Kapoor, P; Kiran, U; Saxena, N, 2000)
"Little information is available regarding the neuromuscular effects of sevoflurane in patients with myasthenia gravis (MG)."3.74Neuromuscular effects of sevoflurane in myasthenia gravis patients. ( Hamada, T; Higa, K; Nitahara, K; Shono, S; Sugi, Y, 2007)
"5% lidocaine with 1:200,000 epinephrine and inhaled anesthesia using nitrous oxide, oxygen and sevoflurane were performed in two patients, (40 and 22 yr-old females) with myasthenia gravis."3.68[Continuous thoracic epidural blockade in combination with general anesthesia with nitrous oxide, oxygen, and sevoflurane in two patients with myasthenia gravis]. ( Fujimura, N; Fujita, S; Kawamata, M; Miyabe, M; Nakae, Y; Namiki, A; Sonoda, H; Sumita, S, 1993)
"Propofol was discontinued when the sternum was approximated."2.74Bispectral index-monitored anesthesia technique for transsternal thymectomy. ( Maddali, MM; Matreja, PV; Zachariah, M, 2009)
"Patients diagnosed with ocular myasthenia gravis (MG) and mitral valve disease represent a significant perioperative management problem, especially for the anaesthesiologist, due to complex inter-actions between the disease, drugs to treat the disease, and anaesthetic agents, such as neuromuscu-lar blocking agents (NMBAs)."1.51Mitral Valve Replacement with Thymectomy in a Patient with Ocular Myasthenia Gravis: Case Report. ( Chioncel, O; Filipescu, D; Geana, RC; Iliescu, VA; Radu, R; Sorostinean, D; Stefan, M; Stiru, O, 2019)
"Myasthenia gravis is characterized by weakness and easy fatiguability of voluntary muscles."1.34Myasthenia gravis and sevoflurane--a case report. ( Dikmen, B; Erk, G; Karabeyoglu, I, 2007)
"Myasthenia gravis is a challenging situation for anaesthesiologists due to its neuromuscular involvement."1.31Sevoflurane as a sole anaesthetic for thymectomy in myasthenia gravis. ( Choudhury, M; Kapoor, P; Kiran, U; Saxena, N, 2000)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.26)18.2507
2000's16 (84.21)29.6817
2010's1 (5.26)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Hien, VV1
Tu, NH1
Thu, ND1
Stiru, O1
Stefan, M1
Geana, RC1
Sorostinean, D1
Radu, R1
Filipescu, D1
Chioncel, O1
Iliescu, VA1
Maddali, MM1
Matreja, PV1
Zachariah, M1
Madi-Jebara, S1
Yazigi, A1
Hayek, G1
Haddad, F1
Antakly, MC1
Nakamura, S1
Nishiyama, T1
Hanaoka, K1
El-Dawlatly, AA1
Al Kattan, K1
Hajjar, W1
Essa, M1
Delvi, B1
Khoja, A1
Nitahara, K1
Sugi, Y1
Higa, K1
Shono, S1
Hamada, T1
López-Berlanga, JL1
Garutti, I1
Martínez-Campos, E1
Piñeiro, P1
Salvatierra, D1
de Vicente Sánchez, J1
Pérez Ferrer, A1
Reinoso Barbero, F1
Erk, G1
Karabeyoglu, I1
Dikmen, B1
Bogaert, F1
Verhaeghen, D1
Herregods, L1
Kwak, YL1
Choi, YS1
Shim, JK1
Choi, EM1
Kawamata, M1
Miyabe, M1
Nakae, Y1
Sonoda, H1
Fujimura, N1
Sumita, S1
Fujita, S1
Namiki, A1
Kiran, U1
Choudhury, M1
Saxena, N1
Kapoor, P1
Baraka, AS1
Taha, SK1
Kawkabani, NI1
Granell Gil, M1
García Aguado, R1
Ferrándiz Roca, L1
Arnau Obrer, A1
Cantó Armengod, A1
Grau Real, F1
Palanca Sanfrancisco, JM1
Baraka, A1
Siddik, S1
el Rassi, T1
Taha, S1
Haroun-Bizri, S1
Wojcieszek, E1
Itoh, H1
Shibata, K1

Trials

1 trial available for sevoflurane and Myasthenia Gravis

ArticleYear
Bispectral index-monitored anesthesia technique for transsternal thymectomy.
    Asian cardiovascular & thoracic annals, 2009, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Electro

2009

Other Studies

18 other studies available for sevoflurane and Myasthenia Gravis

ArticleYear
Propofol TCI or sevoflurane anesthesia without muscle relaxant for thoracoscopic thymectomy in myasthenia gravis patients: a prospective, observational study.
    BMC anesthesiology, 2023, 10-21, Volume: 23, Issue:1

    Topics: Anesthesia, General; Anesthetics, Intravenous; Humans; Methyl Ethers; Muscles; Myasthenia Gravis; Pr

2023
Mitral Valve Replacement with Thymectomy in a Patient with Ocular Myasthenia Gravis: Case Report.
    The heart surgery forum, 2019, Aug-28, Volume: 22, Issue:5

    Topics: Adult; Anesthetics, Combined; Anti-Inflammatory Agents; Drug Interactions; Female; Fentanyl; Heart V

2019
Sevoflurane anesthesia and intrathecal sufentanil-morphine for thymectomy in myasthenia gravis.
    Journal of clinical anesthesia, 2002, Volume: 14, Issue:7

    Topics: Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Injections, Spinal; M

2002
[General anesthesia for diaphragmatic herniorrhaphy in a patient with myasthenia gravis and severe gibbus].
    Masui. The Japanese journal of anesthesiology, 2005, Volume: 54, Issue:12

    Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Female; Hernia, Diaphragmatic; Humans; Methyl Ether

2005
Anesthetic implications for video assisted thoracoscopic thymectomy in myasthenia gravis.
    Middle East journal of anaesthesiology, 2005, Volume: 18, Issue:2

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; A

2005
Neuromuscular effects of sevoflurane in myasthenia gravis patients.
    British journal of anaesthesia, 2007, Volume: 98, Issue:3

    Topics: Adult; Aged; Anesthetics, Inhalation; Dose-Response Relationship, Drug; Electric Stimulation; Electr

2007
[Bilateral paravertebral block anesthesia for thymectomy by video-assisted thoracoscopy in patients with myasthenia gravis].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:9

    Topics: Adult; Analgesia; Androstanols; Anesthesia, Inhalation; Anesthetics, Local; Combined Modality Therap

2006
[Anesthesia with remifentanil for thoracoscopic thymectomy in a girl with myasthenia gravis].
    Revista espanola de anestesiologia y reanimacion, 2007, Volume: 54, Issue:1

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous;

2007
Myasthenia gravis and sevoflurane--a case report.
    Middle East journal of anaesthesiology, 2007, Volume: 19, Issue:1

    Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Female; Humans; Methyl Ethers; Monitoring, I

2007
Myasthenia gravis and thymectomy: an anaesthetic approach.
    Acta anaesthesiologica Belgica, 2007, Volume: 58, Issue:3

    Topics: Anesthesia; Humans; Male; Methyl Ethers; Middle Aged; Myasthenia Gravis; Neuromuscular Blocking Agen

2007
Persistent train-of-four fade in myasthenia gravis patients after sevoflurane anaesthesia.
    British journal of anaesthesia, 2008, Volume: 100, Issue:5

    Topics: Anesthetics, Inhalation; Electromyography; Humans; Methyl Ethers; Monitoring, Physiologic; Myastheni

2008
[Continuous thoracic epidural blockade in combination with general anesthesia with nitrous oxide, oxygen, and sevoflurane in two patients with myasthenia gravis].
    Masui. The Japanese journal of anesthesiology, 1993, Volume: 42, Issue:6

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics; Ethers; Female; Humans; Lidocaine;

1993
Sevoflurane as a sole anaesthetic for thymectomy in myasthenia gravis.
    Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:3

    Topics: Anesthetics, Inhalation; Child; Humans; Male; Methyl Ethers; Myasthenia Gravis; Sevoflurane; Thymect

2000
Neuromuscular interaction of sevoflurane--cisatracurium in a myasthenic patient.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2000, Volume: 47, Issue:6

    Topics: Adult; Anesthetics, Inhalation; Atracurium; Drug Synergism; Female; Humans; Methyl Ethers; Myastheni

2000
[Fastrach laryngeal mask, sevoflurane and remifentanil: an anesthetic alternative for the myasthenic patient].
    Revista espanola de anestesiologia y reanimacion, 2001, Volume: 48, Issue:2

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Laryngeal Masks; Male; Methyl Ethers; Mid

2001
Sevoflurane anesthesia in a myasthenic patient undergoing transsternal thymectomy.
    Middle East journal of anaesthesiology, 2000, Volume: 15, Issue:6

    Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Electromyography; Humans; Male; Methyl Ether

2000
[Application of sevoflurane in the anesthesia of the patient with myasthenia gravis thymectomized using video-thoracoscopic technique: a case report].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2001, Volume: 54, Issue:5-6

    Topics: Adolescent; Anesthetics, Inhalation; Female; Humans; Methyl Ethers; Myasthenia Gravis; Sevoflurane;

2001
Comparison between sevoflurane and propofol neuromuscular effects in a patient with myasthenia gravis: effective doses of vecuronium.
    Anesthesiology, 2001, Volume: 95, Issue:3

    Topics: Adult; Anesthetics; Humans; Male; Methyl Ethers; Myasthenia Gravis; Neuromuscular Junction; Neuromus

2001