sevoflurane has been researched along with Local Neoplasm Recurrence in 6 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We tested the primary hypothesis that breast cancer recurrence after potentially curative surgery is lower with regional anaesthesia-analgesia using paravertebral blocks and the anaesthetic propofol than with general anaesthesia with the volatile anaesthetic sevoflurane and opioid analgesia." | 5.30 | Recurrence of breast cancer after regional or general anaesthesia: a randomised controlled trial. ( Ayad, S; Buggy, DJ; Fleischmann, E; Grady, M; Huang, Y; Kurz, A; Marhofer, P; Mascha, EJ; Mayers, DB; Meyer-Treschan, TA; Pei, L; Sessler, DI; Tan, EY, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dubowitz, J | 1 |
| Ziegler, AI | 1 |
| Beare, R | 1 |
| Jost-Brinkmann, F | 1 |
| Walker, AK | 1 |
| Gillis, RD | 1 |
| Chang, A | 1 |
| Chung, NC | 1 |
| Martin, OA | 1 |
| Hollande, F | 1 |
| Riedel, B | 1 |
| Sloan, EK | 1 |
| Sessler, DI | 1 |
| Pei, L | 1 |
| Huang, Y | 1 |
| Fleischmann, E | 1 |
| Marhofer, P | 1 |
| Kurz, A | 1 |
| Mayers, DB | 1 |
| Meyer-Treschan, TA | 1 |
| Grady, M | 1 |
| Tan, EY | 1 |
| Ayad, S | 1 |
| Mascha, EJ | 1 |
| Buggy, DJ | 1 |
| Cata, JP | 1 |
| Forget, P | 1 |
| Zhang, J | 1 |
| Chang, CL | 1 |
| Lu, CY | 1 |
| Chen, HM | 1 |
| Wu, SY | 1 |
| Evans, DR | 1 |
| Fowler-Williams, C | 1 |
| Ma, D | 1 |
| Weatherall, AD | 1 |
| Bennett, TR | 1 |
| Lovell, M | 1 |
| Fung, W | 1 |
| de Lima, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Regional Anesthesia and Breast Cancer Recurrence[NCT00418457] | Phase 3 | 2,108 participants (Actual) | Interventional | 2007-01-31 | Completed | ||
| Impact of Erector Spinae Plane Block With Adjuvant Dexmedetomidine on Chronic Postsurgical Pain in Breast Cancer Patients: a Two-center Randomized Controlled Trial[NCT05494502] | 1,206 participants (Anticipated) | Interventional | 2023-05-23 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
time to breast cancer recurrence from the end of surgery. (NCT00418457)
Timeframe: up to 10 years
| Intervention | participants (Number) |
|---|---|
| General Anesthesia and Opioid | 111 |
| Regional Analgesia and Propofol | 102 |
neuropathic pain is a binary outcome: any pain vs. no pain (NCT00418457)
Timeframe: 6 month and 1 year
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| at 6-month | 1-year | |
| General Anesthesia and Opioid | 89 | 57 |
| Regional Analgesia and Propofol | 87 | 57 |
Brief Pain Inventory is used to evaluate with values of any pain vs. no pain (binary) (NCT00418457)
Timeframe: 6 months and 1 year
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| at 6-month | 1-year | |
| General Anesthesia and Opioid | 456 | 232 |
| Regional Analgesia and Propofol | 442 | 239 |
Physical and Mental Health Composite Scores (PCS & MCS) are computed using the scores of twelve questions and range from 0 to 100, where a zero score indicates the lowest level of health measured by the scales and 100 indicates the highest level of health. (NCT00418457)
Timeframe: 6 month and 1 year
| Intervention | units on a scale (Mean) | |
|---|---|---|
| at 6-month | 1-year | |
| General Anesthesia and Opioid | 48.1 | 48 |
| Regional Analgesia and Propofol | 48.7 | 48.7 |
Physical and Mental Health Composite Scores (PCS & MCS) are computed using the scores of twelve questions and range from 0 to 100, where a zero score indicates the lowest level of health measured by the scales and 100 indicates the highest level of health. (NCT00418457)
Timeframe: 6 month and 1 year
| Intervention | score on a scale (Mean) | |
|---|---|---|
| at 6-month | 1-year | |
| General Anesthesia and Opioid | 49.7 | 52.3 |
| Regional Analgesia and Propofol | 49.8 | 52.1 |
1 review available for sevoflurane and Local Neoplasm Recurrence
| Article | Year |
|---|---|
Is Volatile Anesthesia During Cancer Surgery Likely to Increase the Metastatic Risk?
Topics: Anesthesia; Anesthetics, Inhalation; Humans; Isoflurane; Methyl Ethers; Neoplasm Metastasis; Neoplas | 2016 |
1 trial available for sevoflurane and Local Neoplasm Recurrence
| Article | Year |
|---|---|
Recurrence of breast cancer after regional or general anaesthesia: a randomised controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, Conduction; Anesthesia, General; Ane | 2019 |
4 other studies available for sevoflurane and Local Neoplasm Recurrence