Page last updated: 2024-11-04

sevoflurane and Liver Neoplasms

sevoflurane has been researched along with Liver Neoplasms in 12 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Liver Neoplasms: Tumors or cancer of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"Remifentanil is widely used for ultrasound-guided percutaneous radiofrequency ablation (RFA) of small hepatocellular carcinoma (HCC)."9.30Comparison of dexmedetomidine vs. remifentanil combined with sevoflurane during radiofrequency ablation of hepatocellular carcinoma: a randomized controlled trial. ( Chen, HX; He, Y; Hei, Z; Jian, C; Li, X; Pan, J; Zhou, S, 2019)
"Hepatocellular carcinoma (HCC) cells were treated with sevoflurane for 12 or 24 h."8.31Sevoflurane suppresses hepatocellular carcinoma cell progression via circ_0001649/miR-19a-3p/SGTB axis. ( Gong, J; Liu, J; Sun, N; Yang, X; Zhang, W, 2023)
"We investigated the effects of sevoflurane exposure on the expression of matrix metalloproteinase (MMP), expression and ablation of natural killer group 2, member D (NKG2D) ligands (UL16-binding proteins 1-3 and major histocompatibility complex class I chain-related molecules A/B), and natural killer (NK) cell-mediated cytotoxicity in breast cancer cells."8.31Effects of sevoflurane on metalloproteinase and natural killer group 2, member D (NKG2D) ligand expression and natural killer cell-mediated cytotoxicity in breast cancer: an in vitro study. ( Bae, J; Hong, JM; Jeon, S; Kim, HJ; Kim, JR; Kwon, SK; Lee, HJ; Paek, SI; Park, S; Ri, HS; Yun, EJ, 2023)
"Sevoflurane (SEVO) inactivates the aggressiveness of hepatocellular carcinoma (HCC) cells by mediating microRNAs (miRNAs)."8.02microRNA-148a-3p enhances the effects of sevoflurane on hepatocellular carcinoma cell progression via ROCK1 repression. ( Liu, L; Sun, H; Sun, Y; Xing, W, 2021)
"Sevoflurane (SEVO) is widely applied as an anesthetic, which exerts antitumor capacity in various cancers, including hepatocellular carcinoma (HCC)."8.02lncRNA KCNQ1OT1 reverses the effect of sevoflurane on hepatocellular carcinoma progression via regulating the miR-29a-3p/CBX3 axis. ( Li, H; Liu, F; Shang, S; Zhou, W, 2021)
"Compared with sevoflurane anesthesia, propofol may improve postoperative Aβ-42 and Tau protein levels in patients with hepatocellular carcinoma, and ameliorate postoperative cognitive function."7.91Effect of propofol and sevoflurane anesthesia on postoperative cognitive function and levels of Aβ-42 and Tau in patients undergoing hepatectomy. ( Hou, JF; Xiao, CL, 2019)
"Remifentanil is widely used for ultrasound-guided percutaneous radiofrequency ablation (RFA) of small hepatocellular carcinoma (HCC)."5.30Comparison of dexmedetomidine vs. remifentanil combined with sevoflurane during radiofrequency ablation of hepatocellular carcinoma: a randomized controlled trial. ( Chen, HX; He, Y; Hei, Z; Jian, C; Li, X; Pan, J; Zhou, S, 2019)
"Hepatocellular carcinoma (HCC) cells were treated with sevoflurane for 12 or 24 h."4.31Sevoflurane suppresses hepatocellular carcinoma cell progression via circ_0001649/miR-19a-3p/SGTB axis. ( Gong, J; Liu, J; Sun, N; Yang, X; Zhang, W, 2023)
"We investigated the effects of sevoflurane exposure on the expression of matrix metalloproteinase (MMP), expression and ablation of natural killer group 2, member D (NKG2D) ligands (UL16-binding proteins 1-3 and major histocompatibility complex class I chain-related molecules A/B), and natural killer (NK) cell-mediated cytotoxicity in breast cancer cells."4.31Effects of sevoflurane on metalloproteinase and natural killer group 2, member D (NKG2D) ligand expression and natural killer cell-mediated cytotoxicity in breast cancer: an in vitro study. ( Bae, J; Hong, JM; Jeon, S; Kim, HJ; Kim, JR; Kwon, SK; Lee, HJ; Paek, SI; Park, S; Ri, HS; Yun, EJ, 2023)
"Sevoflurane (SEVO) inactivates the aggressiveness of hepatocellular carcinoma (HCC) cells by mediating microRNAs (miRNAs)."4.02microRNA-148a-3p enhances the effects of sevoflurane on hepatocellular carcinoma cell progression via ROCK1 repression. ( Liu, L; Sun, H; Sun, Y; Xing, W, 2021)
"Sevoflurane (SEVO) is widely applied as an anesthetic, which exerts antitumor capacity in various cancers, including hepatocellular carcinoma (HCC)."4.02lncRNA KCNQ1OT1 reverses the effect of sevoflurane on hepatocellular carcinoma progression via regulating the miR-29a-3p/CBX3 axis. ( Li, H; Liu, F; Shang, S; Zhou, W, 2021)
"Compared with sevoflurane anesthesia, propofol may improve postoperative Aβ-42 and Tau protein levels in patients with hepatocellular carcinoma, and ameliorate postoperative cognitive function."3.91Effect of propofol and sevoflurane anesthesia on postoperative cognitive function and levels of Aβ-42 and Tau in patients undergoing hepatectomy. ( Hou, JF; Xiao, CL, 2019)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's5 (41.67)24.3611
2020's6 (50.00)2.80

Authors

AuthorsStudies
Sun, N1
Gong, J1
Zhang, W1
Yang, X1
Liu, J2
Sun, X1
Li, Q1
Yang, L1
Kim, HJ1
Jeon, S1
Lee, HJ1
Bae, J1
Ri, HS1
Hong, JM1
Paek, SI1
Kwon, SK1
Kim, JR1
Park, S1
Yun, EJ1
Cao, Y1
Lv, W1
Ding, W1
Li, J1
Sun, Y1
Liu, L1
Xing, W1
Sun, H1
Zhou, W1
Li, H1
Shang, S1
Liu, F1
Pan, J1
Li, X1
He, Y1
Jian, C1
Chen, HX1
Hei, Z1
Zhou, S1
Hou, JF1
Xiao, CL1
Song, G1
Tian, L1
Cheng, Y1
Wang, K1
Li, S1
Li, T1
Rodríguez, A1
Taurà, P1
García Domingo, MI1
Herrero, E1
Camps, J1
Forcada, P1
Sabaté, S1
Cugat, E1
Nishiwada, T1
Kawaraguchi, Y1
Uemura, K1
Sugimoto, H1
Kawaguchi, M1
Beck-Schimmer, B1
Breitenstein, S1
Urech, S1
De Conno, E1
Wittlinger, M1
Puhan, M1
Jochum, W1
Spahn, DR1
Graf, R1
Clavien, PA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Role of Volatile Anesthetics for Hepatic Protection in Ischemia-reperfusion[NCT00516711]0 participants Interventional2006-03-31Completed
Pharmacological Preconditioning With Desflurane in Liver Surgery[NCT03848780]46 participants (Actual)Interventional2016-04-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for sevoflurane and Liver Neoplasms

ArticleYear
Comparison of dexmedetomidine vs. remifentanil combined with sevoflurane during radiofrequency ablation of hepatocellular carcinoma: a randomized controlled trial.
    Trials, 2019, Jan-08, Volume: 20, Issue:1

    Topics: Adult; Aged; Anesthesia, General; Carcinoma, Hepatocellular; Catheter Ablation; Dexmedetomidine; Fem

2019
Hepatic cytoprotective effect of ischemic and anesthetic preconditioning before liver resection when using intermittent vascular inflow occlusion: a randomized clinical trial.
    Surgery, 2015, Volume: 157, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Caspase 3; Female; Hepatectomy; Humans; Isc

2015
A randomized controlled trial on pharmacological preconditioning in liver surgery using a volatile anesthetic.
    Annals of surgery, 2008, Volume: 248, Issue:6

    Topics: Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Colorectal

2008
A randomized controlled trial on pharmacological preconditioning in liver surgery using a volatile anesthetic.
    Annals of surgery, 2008, Volume: 248, Issue:6

    Topics: Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Colorectal

2008
A randomized controlled trial on pharmacological preconditioning in liver surgery using a volatile anesthetic.
    Annals of surgery, 2008, Volume: 248, Issue:6

    Topics: Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Colorectal

2008
A randomized controlled trial on pharmacological preconditioning in liver surgery using a volatile anesthetic.
    Annals of surgery, 2008, Volume: 248, Issue:6

    Topics: Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Colorectal

2008

Other Studies

9 other studies available for sevoflurane and Liver Neoplasms

ArticleYear
Sevoflurane suppresses hepatocellular carcinoma cell progression via circ_0001649/miR-19a-3p/SGTB axis.
    Histology and histopathology, 2023, Volume: 38, Issue:5

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Liver Neopla

2023
Sevoflurane Inhibits lncRNA HOTAIR-Modulated Stability of HK2 mRNA in a m6A-Dependent Manner to Dampen Aerobic Glycolysis and Proliferation in Lung Cancer.
    BioMed research international, 2022, Volume: 2022

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glycolysis;

2022
Effects of sevoflurane on metalloproteinase and natural killer group 2, member D (NKG2D) ligand expression and natural killer cell-mediated cytotoxicity in breast cancer: an in vitro study.
    Korean journal of anesthesiology, 2023, Volume: 76, Issue:6

    Topics: Breast Neoplasms; Carcinoma, Hepatocellular; Female; Humans; Killer Cells, Natural; Ligands; Liver N

2023
Sevoflurane inhibits the proliferation and invasion of hepatocellular carcinoma cells through regulating the PTEN/Akt/GSK‑3β/β‑catenin signaling pathway by downregulating miR‑25‑3p.
    International journal of molecular medicine, 2020, Volume: 46, Issue:1

    Topics: Apoptosis; beta Catenin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Glycogen S

2020
microRNA-148a-3p enhances the effects of sevoflurane on hepatocellular carcinoma cell progression via ROCK1 repression.
    Cellular signalling, 2021, Volume: 83

    Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Humans; Liver Neoplasms; Micr

2021
lncRNA KCNQ1OT1 reverses the effect of sevoflurane on hepatocellular carcinoma progression via regulating the miR-29a-3p/CBX3 axis.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2021, Volume: 54, Issue:7

    Topics: Carcinoma, Hepatocellular; Chromosomal Proteins, Non-Histone; Humans; Liver Neoplasms; MicroRNAs; Po

2021
Effect of propofol and sevoflurane anesthesia on postoperative cognitive function and levels of Aβ-42 and Tau in patients undergoing hepatectomy.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:2

    Topics: Adult; Amyloid beta-Peptides; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcino

2019
Antitumor activity of sevoflurane in HCC cell line is mediated by miR-29a-induced suppression of Dnmt3a.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:10

    Topics: 3' Untranslated Regions; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Cel

2019
Effect of sevoflurane on human hepatocellular carcinoma HepG2 cells under conditions of high glucose and insulin.
    Journal of anesthesia, 2015, Volume: 29, Issue:5

    Topics: Anesthetics, Inhalation; Carcinoma, Hepatocellular; Cell Proliferation; Glucose; Hep G2 Cells; Human

2015