Page last updated: 2024-11-04

sevoflurane and Ischemia

sevoflurane has been researched along with Ischemia in 16 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to investigate the effects of fullerene C60 on rat liver tissue in a liver ischemia reperfusion injury (IRI) model under sevoflurane anesthesia to evaluate the ability of nanoparticles to prevent hepatic complications."8.31Effects of fullerene C60 on liver tissue in liver ischemia reperfusion injury in rats undergoing sevoflurane anesthesia. ( Arslan, M; Kasapbaşı, E; Kavutçu, M; Küçük, A; Kurtipek, Ö; Mortas, T; Ozdemir, C; Tuna, AT; Yavuz, A, 2023)
"To investigate the effect of sevoflurane preconditioning on ischemia/reperfusion (I/R)-induced pulmonary/hepatic injury."7.91Effect of sevoflurane pretreatment in relieving liver ischemia/reperfusion-induced pulmonary and hepatic injury. ( Ma, X; Qu, L; Wang, X; Xiong, Y; Xu, G, 2019)
"Hepatic ischemia induced significant degree of I/R injuries in both isoflurane and sevoflurane non-IP groups."7.85Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats. ( Gwak, MS; Han, S; Jeong, JS; Kim, D; Kim, GS; Kim, KY; Ko, JS; Ryu, S; Shin, BS, 2017)
"Sevoflurane has been shown to improve ischemia/reperfusion injury (IRI) through several mechanisms, including amelioration of inflammatory response."7.83Molecular studies of the immunological effects of the sevoflurane preconditioning in the liver and lung in a rat model of liver ischemia/reperfusion injury. ( Kalimeris, KA; Kostopanagiotou, GG; Lilis, I; Mikrou, A; Nastos, K; Papadaki, H; Papoutsidakis, N; Zarkadis, IK, 2016)
"To evaluate the underlying mechanisms by which sevoflurane protects the liver against ischemia/reperfusion injury evaluate the mechanism by which sevoflurane exerts this protective effect."7.81Mechanisms of the beneficial effect of sevoflurane in liver ischemia/reperfusion injury. ( Cavalcante, FP; Chaib, E; Coelho, AM; D'Albuquerque, LA; Diniz, MA; Machado, MC; Patzina, RA; Sampietre, SN, 2015)
"The Langendorff model was used to determine whether pretreatment with sevoflurane, isoflurane, or ischemic preconditioning (IP) could protect the myocardium of rats against global ischemia."7.70Administration of sevoflurane and isoflurane prior to prolonged global ischemia improves heart function in isolated rat heart. ( Hayes, JK; Li, F; Szakacs, J; Wong, KC, 2000)
"Ischemia was induced by reducing the baseline perfusion pressure from 1."5.29Effects of halothane, isoflurane and sevoflurane on ischemia-reperfusion injury in the perfused liver of fasted rats. ( Imai, M; Inaba, H; Kon, S, 1996)
"To examine the antioxidant role of propofol in ischemia-reperfusion during carotid endarterectomy (CEA) and its influence on cognitive dysfunction after CEA."5.17Cognitive function and oxidative stress after carotid endarterectomy: comparison of propofol to sevoflurane anesthesia. ( Fragopoulou, E; Kakisis, J; Kalimeris, K; Kostopanagiotou, G; Kouni, S; Matsota, P; Nomikos, T; Pandazi, A; Vasdekis, S, 2013)
"This study aimed to investigate the effects of fullerene C60 on rat liver tissue in a liver ischemia reperfusion injury (IRI) model under sevoflurane anesthesia to evaluate the ability of nanoparticles to prevent hepatic complications."4.31Effects of fullerene C60 on liver tissue in liver ischemia reperfusion injury in rats undergoing sevoflurane anesthesia. ( Arslan, M; Kasapbaşı, E; Kavutçu, M; Küçük, A; Kurtipek, Ö; Mortas, T; Ozdemir, C; Tuna, AT; Yavuz, A, 2023)
"To investigate the effect of sevoflurane preconditioning on ischemia/reperfusion (I/R)-induced pulmonary/hepatic injury."3.91Effect of sevoflurane pretreatment in relieving liver ischemia/reperfusion-induced pulmonary and hepatic injury. ( Ma, X; Qu, L; Wang, X; Xiong, Y; Xu, G, 2019)
"Hepatic ischemia induced significant degree of I/R injuries in both isoflurane and sevoflurane non-IP groups."3.85Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats. ( Gwak, MS; Han, S; Jeong, JS; Kim, D; Kim, GS; Kim, KY; Ko, JS; Ryu, S; Shin, BS, 2017)
"Sevoflurane has been shown to improve ischemia/reperfusion injury (IRI) through several mechanisms, including amelioration of inflammatory response."3.83Molecular studies of the immunological effects of the sevoflurane preconditioning in the liver and lung in a rat model of liver ischemia/reperfusion injury. ( Kalimeris, KA; Kostopanagiotou, GG; Lilis, I; Mikrou, A; Nastos, K; Papadaki, H; Papoutsidakis, N; Zarkadis, IK, 2016)
"To evaluate the underlying mechanisms by which sevoflurane protects the liver against ischemia/reperfusion injury evaluate the mechanism by which sevoflurane exerts this protective effect."3.81Mechanisms of the beneficial effect of sevoflurane in liver ischemia/reperfusion injury. ( Cavalcante, FP; Chaib, E; Coelho, AM; D'Albuquerque, LA; Diniz, MA; Machado, MC; Patzina, RA; Sampietre, SN, 2015)
"Ischemia was induced by reducing the baseline perfusion pressure from 1."1.29Effects of halothane, isoflurane and sevoflurane on ischemia-reperfusion injury in the perfused liver of fasted rats. ( Imai, M; Inaba, H; Kon, S, 1996)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's1 (6.25)29.6817
2010's9 (56.25)24.3611
2020's5 (31.25)2.80

Authors

AuthorsStudies
Ji, H1
Li, H1
Zhang, H1
Cheng, Z1
Yu, X1
Ma, X2
Lyu, J1
Jiang, N1
Lu, Y1
Liao, Y1
Wang, K1
Yu, W1
Benoit, L1
Dieu, A1
Foguenne, M1
Bonaccorsi-Riani, E1
Lisnyy, II1
Zakalska, KA1
Burlaka, AA1
Lysykh, SA1
Efimenko, OV1
Yavuz, A1
Tuna, AT1
Ozdemir, C1
Mortas, T1
Küçük, A1
Kasapbaşı, E1
Arslan, M1
Kavutçu, M1
Kurtipek, Ö1
Xu, G1
Wang, X1
Xiong, Y1
Qu, L1
Jeong, JS1
Kim, D1
Kim, KY1
Ryu, S1
Han, S1
Shin, BS1
Kim, GS1
Gwak, MS1
Ko, JS1
Kalimeris, K1
Kouni, S1
Kostopanagiotou, G1
Nomikos, T1
Fragopoulou, E1
Kakisis, J1
Vasdekis, S1
Matsota, P1
Pandazi, A1
Wang, C1
Hu, SM1
Xie, H1
Qiao, SG1
Liu, H1
Liu, CF1
Cavalcante, FP1
Coelho, AM1
Machado, MC1
Sampietre, SN1
Patzina, RA1
Diniz, MA1
Chaib, E1
D'Albuquerque, LA1
Mikrou, A1
Kalimeris, KA1
Lilis, I1
Papoutsidakis, N1
Nastos, K1
Papadaki, H1
Kostopanagiotou, GG1
Zarkadis, IK1
Biedrzycka, A1
Kowalik, M1
Pawlaczyk, R1
Jagielak, D1
Świetlik, D1
Szymanowicz, W1
Lango, R1
Hiltunen, P1
Palve, J1
Setälä, L1
Mustonen, PK1
Berg, L1
Ruokonen, E1
Uusaro, A1
Szabadfi, K1
Danyadi, B1
Kiss, P1
Manavalan, S1
Gabriel, R1
Reglodi, D1
Tamas, A1
Trasy, D1
Batai, I1
Imai, M1
Kon, S1
Inaba, H1
Li, F1
Hayes, JK1
Wong, KC1
Szakacs, J1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Protective Effect of Melatonin in Patients Under Carotid Endarterectomy[NCT03115034]Phase 460 participants (Actual)Interventional2016-06-01Completed
Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Incidence of Postoperative Delirium in Elderly Patients After Cancer Surgery: An Open-label, Randomized Controlled Trial[NCT02662257]1,228 participants (Actual)Interventional2015-04-01Completed
Influence of Cardiopulmonary Bypass and Sevoflurane or Propofol Anesthesia on Tissue Oxygen Saturation of Thenar Muscle in Adults.[NCT02593448]Phase 464 participants (Actual)Interventional2012-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for sevoflurane and Ischemia

ArticleYear
Experimental and Clinical Aspects of Sevoflurane Preconditioning and Postconditioning to Alleviate Hepatic Ischemia-Reperfusion Injury: A Scoping Review.
    International journal of molecular sciences, 2023, Jan-25, Volume: 24, Issue:3

    Topics: Humans; Ischemia; Liver Diseases; Reperfusion Injury; Sevoflurane

2023

Trials

2 trials available for sevoflurane and Ischemia

ArticleYear
Cognitive function and oxidative stress after carotid endarterectomy: comparison of propofol to sevoflurane anesthesia.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:6

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

2013
Cognitive function and oxidative stress after carotid endarterectomy: comparison of propofol to sevoflurane anesthesia.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:6

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

2013
Cognitive function and oxidative stress after carotid endarterectomy: comparison of propofol to sevoflurane anesthesia.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:6

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

2013
Cognitive function and oxidative stress after carotid endarterectomy: comparison of propofol to sevoflurane anesthesia.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:6

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

2013
Aortic cross-clamping phase of cardiopulmonary bypass is related to decreased microvascular reactivity after short-term ischaemia of the thenar muscle both under intravenous and volatile anaesthesia: a randomized trial.
    Interactive cardiovascular and thoracic surgery, 2016, Volume: 23, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhala

2016

Other Studies

13 other studies available for sevoflurane and Ischemia

ArticleYear
Role of microRNA‑218‑5p in sevoflurane‑induced protective effects in hepatic ischemia/reperfusion injury mice by regulating GAB2/PI3K/AKT pathway.
    Molecular medicine reports, 2022, Volume: 25, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Ischemia; Liver; Liver Diseases; Male; Mic

2022
Ferroptosis involved in sevoflurane-aggravated young rats brain injury induced by liver transplantation.
    Neuroreport, 2022, 11-02, Volume: 33, Issue:16

    Topics: Animals; Brain Injuries; Child; Deferoxamine; Ferroptosis; Humans; Iron; Ischemia; Liver; Liver Tran

2022
PREVENTION OF PATHOLOGICAL EFFECT OF ISCHEMIA-REPERFUSION IN LIVER RESECTION BY SEVOFLURANE PRECONDITIONING.
    Experimental oncology, 2023, 10-11, Volume: 45, Issue:2

    Topics: Anesthetics, Inhalation; Humans; Ischemia; Ischemic Preconditioning; Lactates; Prospective Studies;

2023
Effects of fullerene C60 on liver tissue in liver ischemia reperfusion injury in rats undergoing sevoflurane anesthesia.
    The Libyan journal of medicine, 2023, Volume: 18, Issue:1

    Topics: Anesthesia; Animals; Female; Ischemia; Liver; Rats; Rats, Wistar; Reperfusion Injury; Sevoflurane; T

2023
Effect of sevoflurane pretreatment in relieving liver ischemia/reperfusion-induced pulmonary and hepatic injury.
    Acta cirurgica brasileira, 2019, Volume: 34, Issue:8

    Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Disease Models,

2019
Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats.
    Transplantation proceedings, 2017, Volume: 49, Issue:9

    Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Ischemia; Ischemic Precond

2017
Role of mitochondrial ATP-sensitive potassium channel-mediated PKC-ε in delayed protection against myocardial ischemia/reperfusion injury in isolated hearts of sevoflurane-preconditioned rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2015, Volume: 48, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Blotting, Western; Caspase 8; Decanoic Acids; Heart; Hemodynamics;

2015
Mechanisms of the beneficial effect of sevoflurane in liver ischemia/reperfusion injury.
    Acta cirurgica brasileira, 2015, Volume: 30, Issue:11

    Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Capillary Perme

2015
Molecular studies of the immunological effects of the sevoflurane preconditioning in the liver and lung in a rat model of liver ischemia/reperfusion injury.
    Molecular immunology, 2016, Volume: 72

    Topics: Animals; Apoptosis; Complement Activation; Complement C3; Intercellular Adhesion Molecule-1; Ischemi

2016
The effects of hypotension and norepinephrine on microvascular flap perfusion.
    Journal of reconstructive microsurgery, 2011, Volume: 27, Issue:7

    Topics: Animals; Female; Glucose; Hypotension; Ischemia; Lactic Acid; Methyl Ethers; Microdialysis; Microsur

2011
Preconditioning with volatile anaesthetic sevoflurane in ischemic retinal lesion in rats.
    Journal of molecular histology, 2012, Volume: 43, Issue:5

    Topics: Animals; Carotid Arteries; Eye; Ischemia; Ischemic Preconditioning; Methyl Ethers; Rats; Rats, Wista

2012
Effects of halothane, isoflurane and sevoflurane on ischemia-reperfusion injury in the perfused liver of fasted rats.
    Acta anaesthesiologica Scandinavica, 1996, Volume: 40, Issue:10

    Topics: Anesthetics, Inhalation; Animals; Ethers; Halothane; Ischemia; Isoflurane; L-Lactate Dehydrogenase;

1996
Administration of sevoflurane and isoflurane prior to prolonged global ischemia improves heart function in isolated rat heart.
    Acta anaesthesiologica Sinica, 2000, Volume: 38, Issue:3

    Topics: Anesthetics, Inhalation; Animals; In Vitro Techniques; Ischemia; Ischemic Preconditioning, Myocardia

2000