sevoflurane has been researched along with Injury, Ischemia-Reperfusion in 157 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Excerpt | Relevance | Reference |
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"From our results, the positive preconditioning impact of sevoflurane on ischemia-reperfusion injury in patients undergoing free flap surgery is expressed in the early postoperative hours, but it does not persist in the long-term." | 9.22 | Protective effect of sevoflurane preconditioning on ischemia-reperfusion injury in patients undergoing reconstructive plastic surgery with microsurgical flap, a randomized controlled trial. ( Claroni, C; Covotta, M; Forastiere, E; Marcelli, ME; Naccarato, A; Scotto Di Uccio, A; Sofra, M; Torregiani, G, 2016) |
" The authors tested whether inhalation of sevoflurane at subanesthetic concentrations provides protection against postocclusive endothelial dysfunction induced by ischemia-reperfusion injury of the forearm in humans." | 9.12 | Sevoflurane inhalation at sedative concentrations provides endothelial protection against ischemia-reperfusion injury in humans. ( Aguirre, J; Ambrosio, S; Härter, L; Herrmann, P; Keel, M; Lucchinetti, E; Meier, T; Zaugg, M, 2007) |
"To investigate the protective effect of sevoflurane preconditioning on renal ischemia-reperfusion injury (renalischemiareperfusionmodel, RIRI) and its related mechanism." | 8.31 | Sevoflurane participates in the protection of rat renal ischemia-reperfusion injury by down-regulating the expression of TRPM7. ( Deng, R; Gan, T; Pan, X; Sheng, Z; Xu, D; Xu, X; Zou, L, 2023) |
"We aimed to study the influence of sevoflurane on the nucleotide-binding domain and Leucine-rich repeat protein 3 (NLRP3) pathways in rats with cerebral ischemia/reperfusion (I/R) injury." | 8.31 | Sevoflurane preconditioning improves neuroinflammation in cerebral ischemia/reperfusion induced rats through ROS-NLRP3 pathway. ( Shang, S; Shao, W; Sun, F; Wang, Z; Yi, X; Yu, J; Yu, L; Zhu, Y, 2023) |
"This study aimed to investigate the effects of fullerene C60 on rat liver tissue in a liver ischemia reperfusion injury (IRI) model under sevoflurane anesthesia to evaluate the ability of nanoparticles to prevent hepatic complications." | 8.31 | Effects of fullerene C60 on liver tissue in liver ischemia reperfusion injury in rats undergoing sevoflurane anesthesia. ( Arslan, M; Kasapbaşı, E; Kavutçu, M; Küçük, A; Kurtipek, Ö; Mortas, T; Ozdemir, C; Tuna, AT; Yavuz, A, 2023) |
"The inhaled sevoflurane (Sev) has been demonstrated to protect multiple organs against ischemia/reperfusion injury (IRI)." | 8.12 | Sevoflurane activates MEF2D-mediated Wnt/β-catenin signaling pathway via microRNA-374b-5p to affect renal ischemia/reperfusion injury. ( Guan, X; Peng, Q; Wang, J, 2022) |
"To determine whether sevoflurane postconditioning protects against cerebral ischemia reperfusion (I/R) injury and its potential mechanism, we employed bioinformatic analysis, neurological assessments, and western blot analysis, as well as triphenyl tetrazolium chloride, hematoxylin and eosin, Nissl, and immunofluorescence staining." | 8.12 | Sevoflurane postconditioning ameliorates cerebral ischemia-reperfusion injury in rats via TLR4/MyD88/TRAF6 signaling pathway. ( Chi, F; Hou, Z; Li, Y; Ma, L; Wang, Q; Zhao, Z, 2022) |
"Sevoflurane (SEV) has been reported to be an effective neuroprotective agent for cerebral ischemia/reperfusion injury (CIRI)." | 8.02 | Sevoflurane protects against cerebral ischemia/reperfusion injury via microrna-30c-5p modulating homeodomain-interacting protein kinase 1. ( Deng, M; Li, G; Qu, Y; Su, G, 2021) |
"Sevoflurane (Sevo) prevents hypoxia/reoxygenation (H/R)-induced cardiomyocytes apoptosis." | 8.02 | Sevoflurane inhibits the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes via regulating miR-27a-3p-mediated autophagy. ( Chen, S; Hu, Y; Zhan, B; Zhang, Q; Zhang, Y, 2021) |
"To investigate the expression of miR-203 by sevoflurane treatment and its effect on neuroinflammation induced by cerebral ischemia-reperfusion." | 7.96 | Sevoflurane Post-treatment Upregulated miR-203 Expression to Attenuate Cerebral Ischemia-Reperfusion-Induced Neuroinflammation by Targeting MyD88. ( Chen, H; Gu, C; Zhong, H, 2020) |
"To explore the specific mechanism of sevoflurane in alleviating cerebral ischemia-reperfusion injury (CIRI) in rats through the c-Jun N-terminal kinase (JNK) signaling pathway." | 7.96 | Research on mechanism of sevoflurane in alleviating cerebral ischemia-reperfusion injury in rats through JNK signaling pathway. ( Guo, YQ; Hao, YH; Hu, CY; Qi, YH; Zheng, LN, 2020) |
"Objective To determine whether regulatory T cells (Tregs) are involved in sevoflurane preconditioning-induced brain protection against cerebral ischemia/reperfusion injury." | 7.91 | [Regulatory T cells are involved in sevoflurane preconditioning-induced mouse brain protection against cerebral ischemia injury]. ( Chen, J; Jia, W; Wang, S; Wei, H; Zhen, L, 2019) |
"To investigate the effect of sevoflurane preconditioning on ischemia/reperfusion (I/R)-induced pulmonary/hepatic injury." | 7.91 | Effect of sevoflurane pretreatment in relieving liver ischemia/reperfusion-induced pulmonary and hepatic injury. ( Ma, X; Qu, L; Wang, X; Xiong, Y; Xu, G, 2019) |
"To investigate the effect of sevoflurane on hepatic ischemia-reperfusion injury in rats via janus kinase 2/signal transducer and activator of transcription 3 (JAK2-STAT3) pathway." | 7.91 | Effect of sevoflurane on hepatic ischemia-reperfusion injury in rats via JAK2-STAT3 pathway. ( Ma, XW; Sima, LJ, 2019) |
"Propofol may help to protect against ischaemic acute kidney injury (AKI); however, research on this topic is sparse." | 7.91 | Effect of sevoflurane-based or propofol-based anaesthesia on the incidence of postoperative acute kidney injury: A retrospective propensity score-matched analysis. ( Han, S; Jheon, S; Ji, E; Kim, J; Kim, K; Oh, TK, 2019) |
"Sevoflurane (sevo) has been reported to be an effective neuroprotective agent in cerebral ischemia/reperfusion injury (CIRI)." | 7.91 | Sevoflurane prevents miR-181a-induced cerebral ischemia/reperfusion injury. ( Ai, Y; Shan, Z; Zhang, Y; Zhao, Y, 2019) |
"We aim to investigate the effects of sevoflurane on the ATPase activity of the hippocampal neurons in rats with cerebral ischemia-reperfusion injury (IRI) via the cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA) signaling pathway." | 7.88 | Effect of sevoflurane on the ATPase activity of hippocampal neurons in a rat model of cerebral ischemia-reperfusion injury via the cAMP-PKA signaling pathway. ( Cheng, AB; Gao, XZ; Liu, TJ; Tan, ZB; Wang, JJ; Zhang, JC; Zhang, PP; Zhang, SB, 2018) |
"The aim of the study was to investigate the anti-inflammatory effect of sevoflurane post-conditioning on cerebral ischemia-reperfusion injury in rats." | 7.88 | Effects of sevoflurane post-conditioning in cerebral ischemia-reperfusion injury via TLR4/NF-κB pathway in rats. ( Ding, YB; Jin, FYJ; Li, KZ; Li, T; Ma, JH; Pan, WZ; Qiao, LY; Shi, CX, 2018) |
" Sevoflurane postconditioning prevents neuronal apoptosis against cerebral ischemia/reperfusion injury." | 7.88 | Sevoflurane postconditioning improves the spatial learning and memory impairments induced by hemorrhagic shock and resuscitation through suppressing IRE1α-caspase-12-mediated endoplasmic reticulum stress pathway. ( Duan, X; Hu, X; Huang, C; Huang, L; Zhang, M; Zhang, Q; Zhang, Y, 2018) |
"Rat brain endothelial cells (RBE4) were exposed to severe hypoxia and reoxygenated in air in the presence or absence of sevoflurane." | 7.85 | Sevoflurane protects rat brain endothelial barrier structure and function after hypoxia-reoxygenation injury. ( Beck-Schimmer, B; Booy, C; Dumrese, C; Kajdi, ME; Restin, T; Roth Z'graggen, B; Schläpfer, M, 2017) |
"Hepatic ischemia induced significant degree of I/R injuries in both isoflurane and sevoflurane non-IP groups." | 7.85 | Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats. ( Gwak, MS; Han, S; Jeong, JS; Kim, D; Kim, GS; Kim, KY; Ko, JS; Ryu, S; Shin, BS, 2017) |
"Preconditioning or postconditioning of lungs using sevoflurane exhibits a significant protective effect against early phase of ischemia-reperfusion injury in a rat lung transplantation model." | 7.85 | Sevoflurane Attenuates Ischemia-Reperfusion Injury in a Rat Lung Transplantation Model. ( Cypel, M; Guan, Z; Hwang, DM; Keshavjee, S; Kim, H; Liu, M; Marseu, K; McRae, K; Ohsumi, A; Slinger, P, 2017) |
"Sevoflurane has been shown to improve ischemia/reperfusion injury (IRI) through several mechanisms, including amelioration of inflammatory response." | 7.83 | Molecular studies of the immunological effects of the sevoflurane preconditioning in the liver and lung in a rat model of liver ischemia/reperfusion injury. ( Kalimeris, KA; Kostopanagiotou, GG; Lilis, I; Mikrou, A; Nastos, K; Papadaki, H; Papoutsidakis, N; Zarkadis, IK, 2016) |
" Previous studies have demonstrated that sevoflurane, a volatile anesthetic, can preserve the endothelial glycocalyx in heart tissues against ischemia-reperfusion injury." | 7.83 | Protective effects of sevoflurane in hepatic ischemia-reperfusion injury. ( Li, J; Liu, HQ; Lv, GY; Yuan, T; Zhao, X, 2016) |
"Both propofol and sevoflurane attenuated the extent of hepatic ischemia/reperfusion injury which is evident from the hisopathological studies and alterations in liver enzymes such as AST and LDH by inhibiting Nuclear factor kappa B (NFx03BA;B) activation and subsequent alterations in inflammatory cytokines interleukin-1(IL-1), interleukin-6(IL-6), tumor necrosis factor-alpha (TNF-α) and increased IL10 release." | 7.83 | The Effects of Two Anesthetics, Propofol and Sevoflurane, on Liver Ischemia/Reperfusion Injury. ( Qi, F; Wang, H; Wang, Z; Wu, J; Xu, Z; Yu, J, 2016) |
"Potential additive effects of estrogens and sevoflurane against cerebral infarction after transient or permanent middle cerebral artery occlusion (MCAO) have not been addressed." | 7.83 | Protective effects of estrogen combined with sevoflurane in an experimental model of cerebral infarction and focal cerebral ischemia-reperfusion injury. ( Liu, JJ; Pan, SY, 2016) |
"Postconditioning with sevoflurane has been shown to protect against focal cerebral ischemia and reperfusion injury." | 7.81 | Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury involving mitochondrial ATP-dependent potassium channel and mitochondrial permeability transition pore. ( Liu, XZ; Wang, JK; Wu, HF; Yang, B; Zhou, H, 2015) |
"To evaluate the underlying mechanisms by which sevoflurane protects the liver against ischemia/reperfusion injury evaluate the mechanism by which sevoflurane exerts this protective effect." | 7.81 | Mechanisms of the beneficial effect of sevoflurane in liver ischemia/reperfusion injury. ( Cavalcante, FP; Chaib, E; Coelho, AM; D'Albuquerque, LA; Diniz, MA; Machado, MC; Patzina, RA; Sampietre, SN, 2015) |
"To investigate the effect of sevoflurane on tissue permeability of lung ischemia-reperfusion injury (LIRI) in rats." | 7.80 | Effect of sevoflurane on tissue permeability of lung ischemia-reperfusion injury in rats. ( Che, JB; Li, XH; Li, Y; Liu, WC; Liu, ZH; Ma, HB; Shi, GN; Zhao, H, 2014) |
"The aim of current study was to investigate the protective effect of sevoflurane preconditioning at different doses on hepatic ischaemia/reperfusion injury in rats." | 7.79 | Protective effect of sevoflurane on hepatic ischaemia/reperfusion injury in the rat: A dose-response study. ( Jiang, P; Liu, H; Liu, L; Zhou, SP, 2013) |
"It has been proved that sevoflurane postconditioning (SpostC) could protect the heart against myocardial ischemia/reperfusion injury, however, there has been few research focused on the electrophysiological effects of SpostC." | 7.78 | Sevoflurane postconditioning alleviates action potential duration shortening and L-type calcium current suppression induced by ischemia/reperfusion injury in rat epicardial myocytes. ( Fang, NX; Gong, JS; Huang, J; Li, LH; Yao, YT, 2012) |
" The present study examined the hypothesis that neuroprotection of sevoflurane postconditioning (PostC) against spinal cord reperfusion injury is associated with free radicals-mediated up-regulation of antioxidant enzymes in rabbits." | 7.77 | Sevoflurane postconditioning attenuates spinal cord reperfusion injury through free radicals-mediated up-regulation of antioxidant enzymes in rabbits. ( Chen, Q; Deng, J; Ding, Q; Lu, Y; Peng, Y; Wang, Q; Xiong, L; Yang, Q, 2011) |
"Postconditioning with sevoflurane reduces neuronal damage after OGD-reperfusion injury in the CA1 area of rat hippocampus, in vitro." | 7.77 | Sevoflurane postconditioning ameliorates oxygen-glucose deprivation-reperfusion injury in the rat hippocampus. ( Kalikiri, P; Liu, GJ; Mychaskiw, G; Peng, S; Shen, ZY; Wang, GL; Zhang, D; Zhang, Y, 2011) |
"The roles of reactive oxygen species (ROS), extracellular signal-regulated kinase 1/2 (ERK 1/2) and mitochondrial permeability transition pore (mPTP) in sevoflurane postconditioning induced cardioprotection against ischemia-reperfusion injury in Langendorff rat hearts were investigated." | 7.76 | Sevoflurane postconditioning protects isolated rat hearts against ischemia-reperfusion injury: the role of radical oxygen species, extracellular signal-related kinases 1/2 and mitochondrial permeability transition pore. ( Chen, L; Gao, CQ; Li, LB; Li, LH; Wang, WP; Yao, YT, 2010) |
" The hearts with persistent ventricular fibrillation (n=16) present after 15 min of reperfusion were then randomly assigned into one of the two groups: controls (n=8), reperfusion was continued for 25 min without any intervention, and sevoflurane postconditioning (n=8), rat hearts in the sevoflurane postconditioning group were exposed to sevoflurane at a concentration of 8." | 7.75 | Sevoflurane postconditioning converts persistent ventricular fibrillation into regular rhythm. ( Chen, C; Chen, G; Yan, M; Zhang, F, 2009) |
"We evaluated the cardioprotection against myocardial ischemia-reperfusion injury induced by sevoflurane postconditioning (SpostC) in chronically-infarcted rat hearts, and investigated the roles of phosphoinositide 3-kinase (PI3K)-protein kinase B/Akt (PKB/Akt), mitogen-activated extracellular regulated kinase 1/2 (MEK 1/2)-extracellular regulated kinase 1/2 (ERK 1/2), and mitochondrial permeability transition pore (mPTP)." | 7.75 | Sevoflurane postconditioning protects chronically-infarcted rat hearts against ischemia-reperfusion injury by activation of pro-survival kinases and inhibition of mitochondrial permeability transition pore opening upon reperfusion. ( Gao, C; Li, L; Shi, C; Yao, Y, 2009) |
"Sevoflurane pretreatment can protect neuron on ischemia-reperfusion injury by attenuating neuronal apoptosis in rats." | 7.75 | [Protective effects of sevoflurane preconditioning on cerebral ischemia-reperfusion injury in rats]. ( Hu, ZY; Lin, HF; Zhu, ZR, 2009) |
"To investigate whether postconditioning with sevoflurane could alleviate spinal cord ischemia reperfusion injury in rabbits, and whether the beneficial effect is dependent on oxygen free radicals." | 7.74 | [Effect of sevoflurane postconditioning on spinal cord ischemia reperfusion injury via the release of oxygen free radicals in rabbits]. ( Chen, Q; Ma, R; Song, WY; Wang, Q; Xiong, LZ, 2008) |
"Use of sevoflurane compared with propofol attenuated the haemodynamic sequelae of reperfusion injury in our model." | 7.74 | Effects of sevoflurane and propofol on ischaemia-reperfusion injury after thoracic-aortic occlusion in pigs. ( Annecke, T; Bittmann, I; Conzen, PF; Hilberath, JM; Kahr, S; Kemming, GI; Kubitz, JC; Langer, K; Rehm, M, 2007) |
"Preconditioning, but not postconditioning, with Sevoflurane reduces pulmonary neutrophil accumulation after ischaemia/reperfusion injury of the lower body." | 7.74 | Preconditioning, but not postconditioning, with Sevoflurane reduces pulmonary neutrophil accumulation after lower body ischaemia/reperfusion injury in rats. ( Kalb, R; Loer, SA; Schober, P; Schwarte, LA; Weimann, J, 2008) |
" We compared the effect of preconditioning with sevoflurane and preconditioning with short episodes of ischaemia on renal ischaemia/reperfusion injury in the rat in vivo." | 7.73 | Effect of sevoflurane preconditioning on ischaemia/reperfusion injury in the rat kidney in vivo. ( Dettwiler, S; Favoccia, C; Obal, D; Preckel, B; Rascher, K; Schlack, W, 2006) |
" We hypothesized that APC of the rat spinal cord with sevoflurane would reduce neurologic deficit after an ischemic-reperfusion injury." | 7.73 | Anesthetic preconditioning with sevoflurane does not protect the spinal cord after an ischemic-reperfusion injury in the rat. ( Bryant, AJ; Campos, KM; Deal, DD; DeMarco, MP; Mansfield, CM; Tytell, M; Zvara, DA, 2006) |
"Sevoflurane was found to elevate miR-203, and miR-203, in turn, could target and reduce DCX expression." | 5.56 | MicroRNA-203-mediated inhibition of doublecortin underpins cardioprotection conferred by sevoflurane in rats after myocardial ischaemia-reperfusion injury. ( Liu, J; Peng, H; Tan, J; Wu, Z; Yuan, W; Zhang, W, 2020) |
"Sevoflurane was applied in 100% oxygen at a rate of 2." | 5.56 | The Effect of Cerium Oxide on Lung Tissue in Lower Extremity Ischemia Reperfusion Injury in Sevoflurane Administered Rats. ( Arslan, M; Boyunaga, H; Gunes, I; Kucuk, A; Ozdemirkan, A; Sezen, SC; Sivgin, V; Tuncay, A, 2020) |
"Sevoflurane has been widely used during hepatobiliary surgery and was reported to exhibit preconditioning (PreC) properties against hepatic IR injury; however, its postconditioning (PostC) properties remain unknown." | 5.51 | Sevoflurane has postconditioning as well as preconditioning properties against hepatic warm ischemia-reperfusion injury in rats. ( Akiyama, D; Cho, S; Hara, T; Ichinomiya, T; Maekawa, T; Miyaaki, H; Ozawa, E; Shibata, I; Shiraishi, S; Yoshitomi, O, 2019) |
"Sevoflurane pretreatment promoted pulmonary expression of occludin and ZO-1 after reperfusion and inhibited the translocation of PKC-α." | 5.42 | Effects of sevoflurane on tight junction protein expression and PKC-α translocation after pulmonary ischemia-reperfusion injury. ( Chai, J; Chen, W; Han, N; Li, Y; Liu, X; Long, B; Zhao, P, 2015) |
"Sevoflurane pretreatment were performed on WT and HIF-2α knockout mice before renal ischemia/reperfusion." | 5.42 | Sevoflurane pretreatment enhance HIF-2α expression in mice after renal ischemia/reperfusion injury. ( Chen, J; He, Z; Xu, H; Zhan, Q; Zheng, B, 2015) |
"Focal cerebral ischemia was performed via 1h of middle cerebral artery occlusion (MCAO) followed by reperfusion." | 5.39 | Preconditioning with sevoflurane ameliorates spatial learning and memory deficit after focal cerebral ischemia-reperfusion in rats. ( Hu, X; Li, W; Li, Y; Liu, J; Zhang, Y, 2013) |
"Sevoflurane pretreatment comprised exposure to 2." | 5.39 | Effects of sevoflurane pretreatment on renal Src and FAK expression in diabetic rats after renal ischemia/reperfusion injury. ( Liao, WT; Sun, L; Yang, LK; Zhou, SP, 2013) |
"Sixty patients undergoing intracranial aneurysm clipping were randomized into a propofol post-conditioning group or a sevoflurane group." | 5.30 | Propofol post-conditioning after temporary clipping reverses oxidative stress in aneurysm surgery. ( Guo, D; Hua, W; Li, Y; Miao, L; Tang, Q; Wang, G; Wang, H; Wang, X, 2019) |
"Ischemia was induced by reducing the baseline perfusion pressure from 1." | 5.29 | Effects of halothane, isoflurane and sevoflurane on ischemia-reperfusion injury in the perfused liver of fasted rats. ( Imai, M; Inaba, H; Kon, S, 1996) |
"From our results, the positive preconditioning impact of sevoflurane on ischemia-reperfusion injury in patients undergoing free flap surgery is expressed in the early postoperative hours, but it does not persist in the long-term." | 5.22 | Protective effect of sevoflurane preconditioning on ischemia-reperfusion injury in patients undergoing reconstructive plastic surgery with microsurgical flap, a randomized controlled trial. ( Claroni, C; Covotta, M; Forastiere, E; Marcelli, ME; Naccarato, A; Scotto Di Uccio, A; Sofra, M; Torregiani, G, 2016) |
"The aim of this study is to compare the effects of sevoflurane and propofol on one lung ventilation (OLV) induced ischemia-reperfusion injury (IRI) by determining the blood gas, ischemia-modified albumin (IMA), and malonyldialdehyde (MDA)." | 5.19 | The comparison of the effects of sevoflurane inhalation anesthesia and intravenous propofol anesthesia on oxidative stress in one lung ventilation. ( Beşir, A; Demirci, Y; Dohman, D; Erturk, E; Kayir, S; Kutanis, D; Mentese, A; Topaloglu, S, 2014) |
"These data confirm that TIVA with propofol attenuates oxidative stress related to tourniquet-induced ischaemia-reperfusion injury in children." | 5.17 | Tourniquet-induced ischemia-reperfusion injuries during extremity surgery at children's age: impact of anesthetic chemical structure. ( Budic, I; Cvetkovic, T; Jevtovic-Stoimenov, T; Kitic, D; Kocic, G; Pavlovic, D; Simic, D, 2013) |
" The authors tested whether inhalation of sevoflurane at subanesthetic concentrations provides protection against postocclusive endothelial dysfunction induced by ischemia-reperfusion injury of the forearm in humans." | 5.12 | Sevoflurane inhalation at sedative concentrations provides endothelial protection against ischemia-reperfusion injury in humans. ( Aguirre, J; Ambrosio, S; Härter, L; Herrmann, P; Keel, M; Lucchinetti, E; Meier, T; Zaugg, M, 2007) |
" As the ischemia-reperfusion injury could occur, inhalatory anesthetics as sevoflurane (that attenuate the consequences of this process) seem to be the anesthetics of choice." | 4.85 | Anesthesia for free vascularized tissue transfer. ( Hagau, N; Longrois, D, 2009) |
"To investigate the protective effect of sevoflurane preconditioning on renal ischemia-reperfusion injury (renalischemiareperfusionmodel, RIRI) and its related mechanism." | 4.31 | Sevoflurane participates in the protection of rat renal ischemia-reperfusion injury by down-regulating the expression of TRPM7. ( Deng, R; Gan, T; Pan, X; Sheng, Z; Xu, D; Xu, X; Zou, L, 2023) |
"We aimed to study the influence of sevoflurane on the nucleotide-binding domain and Leucine-rich repeat protein 3 (NLRP3) pathways in rats with cerebral ischemia/reperfusion (I/R) injury." | 4.31 | Sevoflurane preconditioning improves neuroinflammation in cerebral ischemia/reperfusion induced rats through ROS-NLRP3 pathway. ( Shang, S; Shao, W; Sun, F; Wang, Z; Yi, X; Yu, J; Yu, L; Zhu, Y, 2023) |
"This study aimed to investigate the effects of fullerene C60 on rat liver tissue in a liver ischemia reperfusion injury (IRI) model under sevoflurane anesthesia to evaluate the ability of nanoparticles to prevent hepatic complications." | 4.31 | Effects of fullerene C60 on liver tissue in liver ischemia reperfusion injury in rats undergoing sevoflurane anesthesia. ( Arslan, M; Kasapbaşı, E; Kavutçu, M; Küçük, A; Kurtipek, Ö; Mortas, T; Ozdemir, C; Tuna, AT; Yavuz, A, 2023) |
"The inhaled sevoflurane (Sev) has been demonstrated to protect multiple organs against ischemia/reperfusion injury (IRI)." | 4.12 | Sevoflurane activates MEF2D-mediated Wnt/β-catenin signaling pathway via microRNA-374b-5p to affect renal ischemia/reperfusion injury. ( Guan, X; Peng, Q; Wang, J, 2022) |
"To determine whether sevoflurane postconditioning protects against cerebral ischemia reperfusion (I/R) injury and its potential mechanism, we employed bioinformatic analysis, neurological assessments, and western blot analysis, as well as triphenyl tetrazolium chloride, hematoxylin and eosin, Nissl, and immunofluorescence staining." | 4.12 | Sevoflurane postconditioning ameliorates cerebral ischemia-reperfusion injury in rats via TLR4/MyD88/TRAF6 signaling pathway. ( Chi, F; Hou, Z; Li, Y; Ma, L; Wang, Q; Zhao, Z, 2022) |
"Sevoflurane (SEV) has been reported to be an effective neuroprotective agent for cerebral ischemia/reperfusion injury (CIRI)." | 4.02 | Sevoflurane protects against cerebral ischemia/reperfusion injury via microrna-30c-5p modulating homeodomain-interacting protein kinase 1. ( Deng, M; Li, G; Qu, Y; Su, G, 2021) |
"To investigate the role of GluN2A and GluN2B in neuroprotective effect of sevoflurane preconditioning against cerebral ischemia-reperfusion injury (CIRI)." | 4.02 | Neuroprotection of sevoflurane against ischemia/reperfusion-induced brain injury through inhibiting GluN2A/GluN2B-PSD-95-MLK3 module. ( Bo, XM; Jin, L, 2021) |
"Sevoflurane (Sevo) prevents hypoxia/reoxygenation (H/R)-induced cardiomyocytes apoptosis." | 4.02 | Sevoflurane inhibits the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes via regulating miR-27a-3p-mediated autophagy. ( Chen, S; Hu, Y; Zhan, B; Zhang, Q; Zhang, Y, 2021) |
"To investigate the expression of miR-203 by sevoflurane treatment and its effect on neuroinflammation induced by cerebral ischemia-reperfusion." | 3.96 | Sevoflurane Post-treatment Upregulated miR-203 Expression to Attenuate Cerebral Ischemia-Reperfusion-Induced Neuroinflammation by Targeting MyD88. ( Chen, H; Gu, C; Zhong, H, 2020) |
"To explore the specific mechanism of sevoflurane in alleviating cerebral ischemia-reperfusion injury (CIRI) in rats through the c-Jun N-terminal kinase (JNK) signaling pathway." | 3.96 | Research on mechanism of sevoflurane in alleviating cerebral ischemia-reperfusion injury in rats through JNK signaling pathway. ( Guo, YQ; Hao, YH; Hu, CY; Qi, YH; Zheng, LN, 2020) |
"Objective To determine whether regulatory T cells (Tregs) are involved in sevoflurane preconditioning-induced brain protection against cerebral ischemia/reperfusion injury." | 3.91 | [Regulatory T cells are involved in sevoflurane preconditioning-induced mouse brain protection against cerebral ischemia injury]. ( Chen, J; Jia, W; Wang, S; Wei, H; Zhen, L, 2019) |
"To investigate the effect of sevoflurane preconditioning on ischemia/reperfusion (I/R)-induced pulmonary/hepatic injury." | 3.91 | Effect of sevoflurane pretreatment in relieving liver ischemia/reperfusion-induced pulmonary and hepatic injury. ( Ma, X; Qu, L; Wang, X; Xiong, Y; Xu, G, 2019) |
"To investigate the effect of sevoflurane on hepatic ischemia-reperfusion injury in rats via janus kinase 2/signal transducer and activator of transcription 3 (JAK2-STAT3) pathway." | 3.91 | Effect of sevoflurane on hepatic ischemia-reperfusion injury in rats via JAK2-STAT3 pathway. ( Ma, XW; Sima, LJ, 2019) |
"Propofol may help to protect against ischaemic acute kidney injury (AKI); however, research on this topic is sparse." | 3.91 | Effect of sevoflurane-based or propofol-based anaesthesia on the incidence of postoperative acute kidney injury: A retrospective propensity score-matched analysis. ( Han, S; Jheon, S; Ji, E; Kim, J; Kim, K; Oh, TK, 2019) |
"Sevoflurane (sevo) has been reported to be an effective neuroprotective agent in cerebral ischemia/reperfusion injury (CIRI)." | 3.91 | Sevoflurane prevents miR-181a-induced cerebral ischemia/reperfusion injury. ( Ai, Y; Shan, Z; Zhang, Y; Zhao, Y, 2019) |
"We aim to investigate the effects of sevoflurane on the ATPase activity of the hippocampal neurons in rats with cerebral ischemia-reperfusion injury (IRI) via the cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA) signaling pathway." | 3.88 | Effect of sevoflurane on the ATPase activity of hippocampal neurons in a rat model of cerebral ischemia-reperfusion injury via the cAMP-PKA signaling pathway. ( Cheng, AB; Gao, XZ; Liu, TJ; Tan, ZB; Wang, JJ; Zhang, JC; Zhang, PP; Zhang, SB, 2018) |
"The aim of the study was to investigate the anti-inflammatory effect of sevoflurane post-conditioning on cerebral ischemia-reperfusion injury in rats." | 3.88 | Effects of sevoflurane post-conditioning in cerebral ischemia-reperfusion injury via TLR4/NF-κB pathway in rats. ( Ding, YB; Jin, FYJ; Li, KZ; Li, T; Ma, JH; Pan, WZ; Qiao, LY; Shi, CX, 2018) |
"After approval by the institutional animal care and use committee, 36 Japanese White rabbits underwent partial hepatic ischemia for 90 min either under sevoflurane or propofol anesthesia." | 3.88 | Interaction between anesthetic conditioning and ischemic preconditioning on metabolic function after hepatic ischemia-reperfusion in rabbits. ( Kosugi, S; Kotake, Y; Morisaki, H; Nagata, H; Suzuki, T; Yamada, T, 2018) |
" Sevoflurane postconditioning prevents neuronal apoptosis against cerebral ischemia/reperfusion injury." | 3.88 | Sevoflurane postconditioning improves the spatial learning and memory impairments induced by hemorrhagic shock and resuscitation through suppressing IRE1α-caspase-12-mediated endoplasmic reticulum stress pathway. ( Duan, X; Hu, X; Huang, C; Huang, L; Zhang, M; Zhang, Q; Zhang, Y, 2018) |
"The study shows that sevoflurane postconditioning affects apoptosis of hepatocytes after ischemia-reperfusion injury in patients." | 3.88 | Sevoflurane Protects Hepatocytes From Ischemic Injury by Reducing Reactive Oxygen Species Signaling of Hepatic Stellate Cells: Translational Findings Based on a Clinical Trial. ( Beck-Schimmer, B; Booy, C; Köppel, S; Roth Z'graggen, B; Schadde, E; Schläpfer, M; Spahn, DR, 2018) |
"Rat brain endothelial cells (RBE4) were exposed to severe hypoxia and reoxygenated in air in the presence or absence of sevoflurane." | 3.85 | Sevoflurane protects rat brain endothelial barrier structure and function after hypoxia-reoxygenation injury. ( Beck-Schimmer, B; Booy, C; Dumrese, C; Kajdi, ME; Restin, T; Roth Z'graggen, B; Schläpfer, M, 2017) |
"Hepatic ischemia induced significant degree of I/R injuries in both isoflurane and sevoflurane non-IP groups." | 3.85 | Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats. ( Gwak, MS; Han, S; Jeong, JS; Kim, D; Kim, GS; Kim, KY; Ko, JS; Ryu, S; Shin, BS, 2017) |
"The antiapoptotic effects of sevoflurane postconditioning are responsible for neuroprotection against cerebral ischemia-reperfusion injury." | 3.85 | Sevoflurane Postconditioning Reduces Apoptosis by Activating the JAK-STAT Pathway After Transient Global Cerebral Ischemia in Rats. ( Bae, JI; Hwang, JW; Jeon, YT; Kim, E; Kim, HC; Lee, KH; Lim, YJ; Min, SW; Park, HP, 2017) |
" In vivo studies demonstrated that sevoflurane post-conditioning (SpostC) was cardioprotective against ischaemia/reperfusion injury, which was blocked by hyperglycaemia." | 3.85 | High glucose concentration abrogates sevoflurane post-conditioning cardioprotection by advancing mitochondrial fission but dynamin-related protein 1 inhibitor restores these effects. ( Ma, HP; Maimaitili, Y; Wang, J; Wu, JJ; Xie, P; Yang, YN; Yu, J; Zheng, H, 2017) |
"Preconditioning or postconditioning of lungs using sevoflurane exhibits a significant protective effect against early phase of ischemia-reperfusion injury in a rat lung transplantation model." | 3.85 | Sevoflurane Attenuates Ischemia-Reperfusion Injury in a Rat Lung Transplantation Model. ( Cypel, M; Guan, Z; Hwang, DM; Keshavjee, S; Kim, H; Liu, M; Marseu, K; McRae, K; Ohsumi, A; Slinger, P, 2017) |
"Sevoflurane, a widely used inhaled anesthetic, showed valid protective effect against ischemia reperfusion injury in lung, however, the underlying molecular mechanisms has yet to be explained." | 3.85 | Pharmacological postconditioning with sevoflurane activates PI3K/AKT signaling and attenuates cardiopulmonary bypass-induced lung injury in dog. ( Chen, S; Dou, X; Han, M; Li, D; Luo, J; Zhang, H; Zhang, Y, 2017) |
"Sevoflurane has been shown to improve ischemia/reperfusion injury (IRI) through several mechanisms, including amelioration of inflammatory response." | 3.83 | Molecular studies of the immunological effects of the sevoflurane preconditioning in the liver and lung in a rat model of liver ischemia/reperfusion injury. ( Kalimeris, KA; Kostopanagiotou, GG; Lilis, I; Mikrou, A; Nastos, K; Papadaki, H; Papoutsidakis, N; Zarkadis, IK, 2016) |
" Previous studies have demonstrated that sevoflurane, a volatile anesthetic, can preserve the endothelial glycocalyx in heart tissues against ischemia-reperfusion injury." | 3.83 | Protective effects of sevoflurane in hepatic ischemia-reperfusion injury. ( Li, J; Liu, HQ; Lv, GY; Yuan, T; Zhao, X, 2016) |
"Both propofol and sevoflurane attenuated the extent of hepatic ischemia/reperfusion injury which is evident from the hisopathological studies and alterations in liver enzymes such as AST and LDH by inhibiting Nuclear factor kappa B (NFx03BA;B) activation and subsequent alterations in inflammatory cytokines interleukin-1(IL-1), interleukin-6(IL-6), tumor necrosis factor-alpha (TNF-α) and increased IL10 release." | 3.83 | The Effects of Two Anesthetics, Propofol and Sevoflurane, on Liver Ischemia/Reperfusion Injury. ( Qi, F; Wang, H; Wang, Z; Wu, J; Xu, Z; Yu, J, 2016) |
"Potential additive effects of estrogens and sevoflurane against cerebral infarction after transient or permanent middle cerebral artery occlusion (MCAO) have not been addressed." | 3.83 | Protective effects of estrogen combined with sevoflurane in an experimental model of cerebral infarction and focal cerebral ischemia-reperfusion injury. ( Liu, JJ; Pan, SY, 2016) |
"Postconditioning with sevoflurane has been shown to protect against focal cerebral ischemia and reperfusion injury." | 3.81 | Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury involving mitochondrial ATP-dependent potassium channel and mitochondrial permeability transition pore. ( Liu, XZ; Wang, JK; Wu, HF; Yang, B; Zhou, H, 2015) |
"Preconditioning with sevoflurane (SEV) can protect against ischemia-reperfusion injury in several organs, however, the benefits of SEV against acute lung injury (ALI), induced by intestinal ischemia-reperfusion (IIR), and the underlying mechanisms remain to be elucidated." | 3.81 | Sevoflurane ameliorates intestinal ischemia-reperfusion-induced lung injury by inhibiting the synergistic action between mast cell activation and oxidative stress. ( Chen, H; Hei, Z; Luo, C; Luo, G; Su, G; Yuan, D; Zhao, W, 2015) |
"To evaluate the underlying mechanisms by which sevoflurane protects the liver against ischemia/reperfusion injury evaluate the mechanism by which sevoflurane exerts this protective effect." | 3.81 | Mechanisms of the beneficial effect of sevoflurane in liver ischemia/reperfusion injury. ( Cavalcante, FP; Chaib, E; Coelho, AM; D'Albuquerque, LA; Diniz, MA; Machado, MC; Patzina, RA; Sampietre, SN, 2015) |
"To investigate the effect of sevoflurane on tissue permeability of lung ischemia-reperfusion injury (LIRI) in rats." | 3.80 | Effect of sevoflurane on tissue permeability of lung ischemia-reperfusion injury in rats. ( Che, JB; Li, XH; Li, Y; Liu, WC; Liu, ZH; Ma, HB; Shi, GN; Zhao, H, 2014) |
"The aim of current study was to investigate the protective effect of sevoflurane preconditioning at different doses on hepatic ischaemia/reperfusion injury in rats." | 3.79 | Protective effect of sevoflurane on hepatic ischaemia/reperfusion injury in the rat: A dose-response study. ( Jiang, P; Liu, H; Liu, L; Zhou, SP, 2013) |
"Sevoflurane preconditioning protects mitochondria from cerebral ischemia/reperfusion injury and ameliorates long-term neurological deficits." | 3.78 | Sevoflurane preconditioning improves mitochondrial function and long-term neurologic sequelae after transient cerebral ischemia: role of mitochondrial permeability transition. ( Han, J; Kong, X; Li, N; Liu, X; Xiong, L; Yang, Q; Ye, R; Zhang, Y; Zhao, G, 2012) |
"It has been proved that sevoflurane postconditioning (SpostC) could protect the heart against myocardial ischemia/reperfusion injury, however, there has been few research focused on the electrophysiological effects of SpostC." | 3.78 | Sevoflurane postconditioning alleviates action potential duration shortening and L-type calcium current suppression induced by ischemia/reperfusion injury in rat epicardial myocytes. ( Fang, NX; Gong, JS; Huang, J; Li, LH; Yao, YT, 2012) |
" The present study examined the hypothesis that neuroprotection of sevoflurane postconditioning (PostC) against spinal cord reperfusion injury is associated with free radicals-mediated up-regulation of antioxidant enzymes in rabbits." | 3.77 | Sevoflurane postconditioning attenuates spinal cord reperfusion injury through free radicals-mediated up-regulation of antioxidant enzymes in rabbits. ( Chen, Q; Deng, J; Ding, Q; Lu, Y; Peng, Y; Wang, Q; Xiong, L; Yang, Q, 2011) |
"Postconditioning with sevoflurane reduces neuronal damage after OGD-reperfusion injury in the CA1 area of rat hippocampus, in vitro." | 3.77 | Sevoflurane postconditioning ameliorates oxygen-glucose deprivation-reperfusion injury in the rat hippocampus. ( Kalikiri, P; Liu, GJ; Mychaskiw, G; Peng, S; Shen, ZY; Wang, GL; Zhang, D; Zhang, Y, 2011) |
"The roles of reactive oxygen species (ROS), extracellular signal-regulated kinase 1/2 (ERK 1/2) and mitochondrial permeability transition pore (mPTP) in sevoflurane postconditioning induced cardioprotection against ischemia-reperfusion injury in Langendorff rat hearts were investigated." | 3.76 | Sevoflurane postconditioning protects isolated rat hearts against ischemia-reperfusion injury: the role of radical oxygen species, extracellular signal-related kinases 1/2 and mitochondrial permeability transition pore. ( Chen, L; Gao, CQ; Li, LB; Li, LH; Wang, WP; Yao, YT, 2010) |
"Sevoflurane postconditioning prevents activation of caspase 3 and 9, mediators of apoptosis in ischemia-reperfusion injury." | 3.76 | Sevoflurane postconditioning prevents activation of caspase 3 and 9 through antiapoptotic signaling after myocardial ischemia-reperfusion. ( Domae, N; Inamura, Y; Kotani, J; Miyamae, M; Sugioka, S, 2010) |
"Sevoflurane can produce delayed protection against cerebral ischemia-reperfusion injury by down-regulating TNF-alpha, IL-1beta protein, and mRNA expression." | 3.75 | [Sevoflurane preconditioning induced delayed neuroprotection against focal cerebral ischemia in rats]. ( Guo, Q; Pan, Y; Shi, M; Wang, E; Ye, Z, 2009) |
" The hearts with persistent ventricular fibrillation (n=16) present after 15 min of reperfusion were then randomly assigned into one of the two groups: controls (n=8), reperfusion was continued for 25 min without any intervention, and sevoflurane postconditioning (n=8), rat hearts in the sevoflurane postconditioning group were exposed to sevoflurane at a concentration of 8." | 3.75 | Sevoflurane postconditioning converts persistent ventricular fibrillation into regular rhythm. ( Chen, C; Chen, G; Yan, M; Zhang, F, 2009) |
"We evaluated the cardioprotection against myocardial ischemia-reperfusion injury induced by sevoflurane postconditioning (SpostC) in chronically-infarcted rat hearts, and investigated the roles of phosphoinositide 3-kinase (PI3K)-protein kinase B/Akt (PKB/Akt), mitogen-activated extracellular regulated kinase 1/2 (MEK 1/2)-extracellular regulated kinase 1/2 (ERK 1/2), and mitochondrial permeability transition pore (mPTP)." | 3.75 | Sevoflurane postconditioning protects chronically-infarcted rat hearts against ischemia-reperfusion injury by activation of pro-survival kinases and inhibition of mitochondrial permeability transition pore opening upon reperfusion. ( Gao, C; Li, L; Shi, C; Yao, Y, 2009) |
"Sevoflurane pretreatment can protect neuron on ischemia-reperfusion injury by attenuating neuronal apoptosis in rats." | 3.75 | [Protective effects of sevoflurane preconditioning on cerebral ischemia-reperfusion injury in rats]. ( Hu, ZY; Lin, HF; Zhu, ZR, 2009) |
"To investigate whether postconditioning with sevoflurane could alleviate spinal cord ischemia reperfusion injury in rabbits, and whether the beneficial effect is dependent on oxygen free radicals." | 3.74 | [Effect of sevoflurane postconditioning on spinal cord ischemia reperfusion injury via the release of oxygen free radicals in rabbits]. ( Chen, Q; Ma, R; Song, WY; Wang, Q; Xiong, LZ, 2008) |
"Use of sevoflurane compared with propofol attenuated the haemodynamic sequelae of reperfusion injury in our model." | 3.74 | Effects of sevoflurane and propofol on ischaemia-reperfusion injury after thoracic-aortic occlusion in pigs. ( Annecke, T; Bittmann, I; Conzen, PF; Hilberath, JM; Kahr, S; Kemming, GI; Kubitz, JC; Langer, K; Rehm, M, 2007) |
"Preconditioning, but not postconditioning, with Sevoflurane reduces pulmonary neutrophil accumulation after ischaemia/reperfusion injury of the lower body." | 3.74 | Preconditioning, but not postconditioning, with Sevoflurane reduces pulmonary neutrophil accumulation after lower body ischaemia/reperfusion injury in rats. ( Kalb, R; Loer, SA; Schober, P; Schwarte, LA; Weimann, J, 2008) |
"We conclude that the severity of remote lung injury was not different between sevoflurane and propofol anaesthesia in this porcine model of severe lower-body ischaemia and reperfusion injury." | 3.74 | Lung injury following thoracic aortic occlusion: comparison of sevoflurane and propofol anaesthesia. ( Annecke, T; Bittmann, I; Conzen, PF; Hilberath, JM; Kahr, S; Kemming, GI; Krombach, F; Kubitz, JC; Langer, K; Rehm, M, 2008) |
"In the present study, we tested the ability of sevoflurane to induce early and late preconditioning against ischemic neuronal injury using an in vivo model of global cerebral ischemia in the rat." | 3.73 | Sevoflurane-induced preconditioning protects against cerebral ischemic neuronal damage in rats. ( Akca, O; Kehl, F; Payne, RS; Roewer, N; Schurr, A, 2005) |
" We compared the effect of preconditioning with sevoflurane and preconditioning with short episodes of ischaemia on renal ischaemia/reperfusion injury in the rat in vivo." | 3.73 | Effect of sevoflurane preconditioning on ischaemia/reperfusion injury in the rat kidney in vivo. ( Dettwiler, S; Favoccia, C; Obal, D; Preckel, B; Rascher, K; Schlack, W, 2006) |
" We hypothesized that APC of the rat spinal cord with sevoflurane would reduce neurologic deficit after an ischemic-reperfusion injury." | 3.73 | Anesthetic preconditioning with sevoflurane does not protect the spinal cord after an ischemic-reperfusion injury in the rat. ( Bryant, AJ; Campos, KM; Deal, DD; DeMarco, MP; Mansfield, CM; Tytell, M; Zvara, DA, 2006) |
" Seven minutes before hypoxia reoxygenation, muscles were exposed to 4 min of hypoxia and 7 min of reoxygenation or 15 min of sevoflurane at concentrations of 1, 2, and 3%." | 3.72 | Mechanisms of sevoflurane-induced myocardial preconditioning in isolated human right atria in vitro. ( Babatasi, G; Bricard, H; Ducouret, P; Gérard, JL; Haelewyn, B; Hanouz, JL; Khayat, A; Massetti, M; Terrien, X; Yvon, A, 2003) |
"Ischemiareperfusion damage is a major cause of early renal dysfunction during the perioperative period." | 2.90 | Effects of Different Volatile Anesthetics on Cytokine and Chemokine Production After Ischemia-Reperfusion Injury in Patients Undergoing Living-Donor Kidney Transplant. ( Nane, I; Oguz, F; Oktar, T; Savran Karadeniz, M; Senturk Ciftci, H; Tefik, T; Tugrul, KM; Turkmen, A, 2019) |
"Ischemia reperfusion injury (IRI) is inevitable in kidney transplantation and negatively impacts graft and patient outcome." | 2.72 | Molecular Aspects of Volatile Anesthetic-Induced Organ Protection and Its Potential in Kidney Transplantation. ( Bosch, DJ; Leuvenink, HGD; Nieuwenhuijs-Moeke, GJ, 2021) |
"Sevoflurane was found to elevate miR-203, and miR-203, in turn, could target and reduce DCX expression." | 1.56 | MicroRNA-203-mediated inhibition of doublecortin underpins cardioprotection conferred by sevoflurane in rats after myocardial ischaemia-reperfusion injury. ( Liu, J; Peng, H; Tan, J; Wu, Z; Yuan, W; Zhang, W, 2020) |
"Sevoflurane was applied in 100% oxygen at a rate of 2." | 1.56 | The Effect of Cerium Oxide on Lung Tissue in Lower Extremity Ischemia Reperfusion Injury in Sevoflurane Administered Rats. ( Arslan, M; Boyunaga, H; Gunes, I; Kucuk, A; Ozdemirkan, A; Sezen, SC; Sivgin, V; Tuncay, A, 2020) |
"Sevoflurane after-treatment revived the intensity of fluorescence of the endothelial glycocalyx compared to the hydrogen peroxide group." | 1.51 | Sevoflurane Promotes Regeneration of the Endothelial Glycocalyx by Upregulating Sialyltransferase. ( Azumaguchi, R; Hamada, K; Kazuma, S; Kimizuka, M; Tokinaga, Y; Yamakage, M, 2019) |
"Sevoflurane has been widely used during hepatobiliary surgery and was reported to exhibit preconditioning (PreC) properties against hepatic IR injury; however, its postconditioning (PostC) properties remain unknown." | 1.51 | Sevoflurane has postconditioning as well as preconditioning properties against hepatic warm ischemia-reperfusion injury in rats. ( Akiyama, D; Cho, S; Hara, T; Ichinomiya, T; Maekawa, T; Miyaaki, H; Ozawa, E; Shibata, I; Shiraishi, S; Yoshitomi, O, 2019) |
"Bilirubin levels were significantly lower in group 1 versus group 2 at day 1 (3." | 1.43 | Anti-inflammatory signaling during ex vivo liver perfusion improves the preservation of pig liver grafts before transplantation. ( Adeyi, OA; Barbas, AS; Echeverri, J; Goldaracena, N; Grant, DR; Kaths, JM; Louis, KS; Selzner, M; Selzner, N; Spetzler, VN, 2016) |
"Sevoflurane pretreatment promoted pulmonary expression of occludin and ZO-1 after reperfusion and inhibited the translocation of PKC-α." | 1.42 | Effects of sevoflurane on tight junction protein expression and PKC-α translocation after pulmonary ischemia-reperfusion injury. ( Chai, J; Chen, W; Han, N; Li, Y; Liu, X; Long, B; Zhao, P, 2015) |
"Sevoflurane pretreatment were performed on WT and HIF-2α knockout mice before renal ischemia/reperfusion." | 1.42 | Sevoflurane pretreatment enhance HIF-2α expression in mice after renal ischemia/reperfusion injury. ( Chen, J; He, Z; Xu, H; Zhan, Q; Zheng, B, 2015) |
"Hepatic ischemia-reperfusion injury has a significant impact on liver resection and transplantation." | 1.40 | Ischemic versus pharmacologic hepatic preconditioning. ( Azambuja, G; Balzan, SM; de Souza, PL; Gava, VG; Horta, JA; Pra, D; Rieger, A; Schopf, L; Trombini, L; Zenkner, FF, 2014) |
"Sevoflurane has been reported to protect against neuronal apoptosis during cerebral IR." | 1.40 | Sevoflurane preconditioning ameliorates neuronal deficits by inhibiting microglial MMP-9 expression after spinal cord ischemia/reperfusion in rats. ( Cao, XZ; Fang, B; Li, XQ; Ma, H; Tan, WF; Wang, J, 2014) |
"Focal cerebral ischemia was performed via 1h of middle cerebral artery occlusion (MCAO) followed by reperfusion." | 1.39 | Preconditioning with sevoflurane ameliorates spatial learning and memory deficit after focal cerebral ischemia-reperfusion in rats. ( Hu, X; Li, W; Li, Y; Liu, J; Zhang, Y, 2013) |
"Sevoflurane pretreatment comprised exposure to 2." | 1.39 | Effects of sevoflurane pretreatment on renal Src and FAK expression in diabetic rats after renal ischemia/reperfusion injury. ( Liao, WT; Sun, L; Yang, LK; Zhou, SP, 2013) |
"Successful resuscitation after cardiac arrest is typically associated with cerebral and myocardial ischemia/reperfusion (I/R)-injury." | 1.38 | Hypothermia and anesthetic postconditioning influence the expression and activity of small intestinal proteins possibly involved in ischemia/reperfusion-mediated events following cardiopulmonary resuscitation. ( Albrecht, M; Bein, B; Gruenewald, M; Meybohm, P; Scholz, J; Zacharowski, K; Zitta, K, 2012) |
"Ischemia-reperfusion lung injury is doubly important in thoracic surgery because of the associated ventilation damage to 1 lung." | 1.37 | The effects of anesthetic preconditioning with sevoflurane in an experimental lung autotransplant model in pigs. ( Azcarate, L; Casanova, J; Garcia, C; Garutti, I; Giraldez, A; Gonzalez, G; Martin, B; Simon, C; Vara, E, 2011) |
"Ischemia-induced adverse effects such as pulmonary edema and acute brain swelling were observed primarily in propofol-anesthetized rabbits." | 1.36 | Cerebral pial vascular changes under propofol or sevoflurane anesthesia during global cerebral ischemia and reperfusion in rabbits. ( Ichikawa, M; Ishiyama, T; Kiuchi, R; Masamune, T; Matsukawa, T; Sessler, DI; Shibuya, K, 2010) |
"Sevoflurane-treated hearts (1 and 2 MAC) also showed decreased adhesion of PMNs (23 +/- 2." | 1.30 | Halothane, isoflurane, and sevoflurane reduce postischemic adhesion of neutrophils in the coronary system. ( Becker, BF; Conzen, PF; Flaucher, A; Gerlach, E; Kowalski, C; Peter, K; Zahler, S, 1997) |
"Ischemia was induced by reducing the baseline perfusion pressure from 1." | 1.29 | Effects of halothane, isoflurane and sevoflurane on ischemia-reperfusion injury in the perfused liver of fasted rats. ( Imai, M; Inaba, H; Kon, S, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (1.27) | 18.2507 |
2000's | 28 (17.83) | 29.6817 |
2010's | 95 (60.51) | 24.3611 |
2020's | 32 (20.38) | 2.80 |
Authors | Studies |
---|---|
Su, G | 3 |
Qu, Y | 1 |
Li, G | 1 |
Deng, M | 1 |
Ji, H | 1 |
Li, H | 2 |
Zhang, H | 3 |
Cheng, Z | 1 |
Li, T | 2 |
Zeng, QS | 1 |
She, SZ | 1 |
Yang, L | 1 |
Chen, H | 3 |
Guan, L | 1 |
Xu, Y | 2 |
Guan, X | 1 |
Peng, Q | 1 |
Wang, J | 5 |
Yu, X | 1 |
Ma, X | 2 |
Lyu, J | 1 |
Jiang, N | 1 |
Lu, Y | 2 |
Liao, Y | 1 |
Wang, K | 1 |
Yu, W | 1 |
Zhao, Z | 1 |
Li, Y | 11 |
Chi, F | 1 |
Ma, L | 1 |
Hou, Z | 1 |
Wang, Q | 4 |
Liang, Z | 1 |
Lei, S | 1 |
Wu, X | 1 |
Yuan, T | 2 |
Ma, K | 2 |
Chi, K | 1 |
Xu, X | 1 |
Deng, R | 1 |
Zou, L | 1 |
Pan, X | 1 |
Sheng, Z | 1 |
Xu, D | 1 |
Gan, T | 1 |
Benoit, L | 1 |
Dieu, A | 1 |
Foguenne, M | 1 |
Bonaccorsi-Riani, E | 1 |
Shang, S | 1 |
Sun, F | 1 |
Zhu, Y | 1 |
Yu, J | 5 |
Yu, L | 2 |
Shao, W | 1 |
Wang, Z | 3 |
Yi, X | 1 |
Yavuz, A | 1 |
Tuna, AT | 1 |
Ozdemir, C | 1 |
Mortas, T | 1 |
Küçük, A | 2 |
Kasapbaşı, E | 1 |
Arslan, M | 2 |
Kavutçu, M | 1 |
Kurtipek, Ö | 1 |
Zhen, L | 1 |
Jia, W | 1 |
Wei, H | 1 |
Wang, S | 1 |
Chen, J | 3 |
Xu, G | 1 |
Wang, X | 4 |
Xiong, Y | 1 |
Qu, L | 1 |
Liu, C | 3 |
Ding, R | 1 |
Huang, W | 2 |
Miao, L | 4 |
Li, J | 3 |
Shi, CX | 4 |
Jin, J | 1 |
Wang, XQ | 1 |
Song, T | 1 |
Li, GH | 1 |
Li, KZ | 2 |
Ma, JH | 2 |
Zhong, H | 1 |
Gu, C | 1 |
Yamamoto, M | 1 |
Morita, T | 1 |
Ishikawa, M | 1 |
Sakamoto, A | 1 |
Qiu, S | 1 |
Liu, B | 1 |
Mo, Y | 1 |
Zhong, L | 1 |
Han, X | 1 |
Mi, F | 1 |
Deng, Y | 1 |
Shi, C | 2 |
Gu, Y | 1 |
Yang, N | 1 |
Xu, M | 2 |
Xu, T | 1 |
Guo, X | 1 |
Hu, CY | 1 |
Guo, YQ | 1 |
Hao, YH | 1 |
Zheng, LN | 1 |
Qi, YH | 1 |
Yu, F | 1 |
Tong, LJ | 1 |
Cai, DS | 1 |
Maldonado, F | 1 |
Morales, D | 1 |
Gutiérrez, R | 1 |
Barahona, M | 1 |
Cerda, O | 1 |
Cáceres, M | 1 |
Hong, L | 1 |
Sun, Y | 2 |
An, JZ | 1 |
Wang, C | 1 |
Qiao, SG | 1 |
Tan, J | 1 |
Wu, Z | 1 |
Liu, J | 2 |
Zhang, W | 1 |
Yuan, W | 1 |
Peng, H | 1 |
Li, W | 2 |
Zhang, Y | 13 |
Hu, Z | 1 |
Tuncay, A | 1 |
Sivgin, V | 1 |
Ozdemirkan, A | 1 |
Sezen, SC | 1 |
Boyunaga, H | 1 |
Gunes, I | 1 |
Rozier, R | 1 |
Paul, R | 1 |
Madji Hounoum, B | 1 |
Villa, E | 1 |
Mhaidly, R | 1 |
Chiche, J | 1 |
Verhoeyen, E | 1 |
Marchetti, S | 1 |
Vandenberghe, A | 1 |
Raucoules, M | 1 |
Carles, M | 2 |
Ricci, JE | 1 |
Bertani, A | 1 |
Miceli, V | 1 |
De Monte, L | 1 |
Occhipinti, G | 1 |
Pagano, V | 1 |
Liotta, R | 1 |
Badami, E | 1 |
Tuzzolino, F | 1 |
Arcadipane, A | 1 |
Ma, H | 3 |
Yang, B | 2 |
Gao, Y | 1 |
Ye, X | 1 |
Liu, Y | 3 |
Li, Z | 2 |
Li, E | 1 |
Xiao, X | 1 |
Liu, D | 1 |
Chen, S | 3 |
Li, X | 2 |
Ge, M | 1 |
Nieuwenhuijs-Moeke, GJ | 2 |
Bosch, DJ | 1 |
Leuvenink, HGD | 2 |
Jin, L | 1 |
Bo, XM | 1 |
Zhan, B | 1 |
Hu, Y | 1 |
Zhang, Q | 4 |
Nickkholgh, A | 1 |
Maluf, D | 1 |
Nieuwenhuijs, VB | 1 |
Seelen, MAJ | 1 |
Berger, SP | 1 |
van den Heuvel, MC | 1 |
Burgerhof, JGM | 1 |
Ottens, PJ | 1 |
Ploeg, RJ | 1 |
Struys, MMRF | 1 |
Hu, F | 1 |
Wen, J | 1 |
Wei, X | 1 |
Zeng, Y | 2 |
Luo, S | 1 |
Sun, L | 3 |
Restin, T | 1 |
Kajdi, ME | 1 |
Schläpfer, M | 2 |
Roth Z'graggen, B | 2 |
Booy, C | 2 |
Dumrese, C | 1 |
Beck-Schimmer, B | 6 |
Jeong, JS | 1 |
Kim, D | 1 |
Kim, KY | 1 |
Ryu, S | 1 |
Han, S | 2 |
Shin, BS | 1 |
Kim, GS | 1 |
Gwak, MS | 1 |
Ko, JS | 1 |
Liu, TJ | 1 |
Zhang, JC | 1 |
Gao, XZ | 1 |
Tan, ZB | 1 |
Wang, JJ | 1 |
Zhang, PP | 1 |
Cheng, AB | 1 |
Zhang, SB | 1 |
Parapanov, R | 1 |
Francioli, C | 1 |
Perentes, JY | 1 |
Letovanec, I | 1 |
Gonzalez, M | 1 |
Kern, C | 1 |
Ris, HB | 1 |
Piquilloud, L | 1 |
Marcucci, C | 1 |
Krueger, T | 1 |
Liaudet, L | 1 |
Gronchi, F | 1 |
Ding, YB | 1 |
Jin, FYJ | 1 |
Qiao, LY | 1 |
Pan, WZ | 1 |
Hu, X | 4 |
Zhang, L | 3 |
Duan, X | 3 |
Mangus, RS | 1 |
Kinsella, SB | 1 |
Farar, DT | 1 |
Fridell, JA | 1 |
Woolf, LT | 1 |
Kubal, CA | 1 |
Guo, D | 1 |
Wang, H | 2 |
Hua, W | 1 |
Tang, Q | 1 |
Wang, G | 2 |
Yamada, T | 1 |
Nagata, H | 1 |
Kosugi, S | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Sevoflurane vs Propofol Effect on Endothelial Damage Markers After Knee Ligament Surgery. A Randomized Controlled Trial[NCT03772054] | 16 participants (Actual) | Interventional | 2018-12-20 | Completed | |||
"Volatile Anesthetic Protection Of Renal Transplants: VAPOR-1-trail"[NCT01248871] | 120 participants (Actual) | Interventional | 2010-09-30 | Completed | |||
Sevoflurane Protective Effect on Ischemia-reperfusion Injury in Patients Undergoing Reconstructive Plastic Surgery With Microsurgical Flap. Multicenter, Randomized Controlled Trial.[NCT01905501] | 132 participants (Actual) | Interventional | 2013-02-28 | Completed | |||
Role of Volatile Anesthetics for Hepatic Protection in Ischemia-reperfusion[NCT00516711] | 0 participants | Interventional | 2006-03-31 | Completed | |||
Pharmacological Preconditioning With Desflurane in Liver Surgery[NCT03848780] | 46 participants (Actual) | Interventional | 2016-04-01 | Completed | |||
Digestive ENdoscopy afTeR Out-of-hospitAl Cardiac arresT[NCT02349074] | 221 participants (Actual) | Interventional | 2014-11-12 | Completed | |||
Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Long-term Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT02660411] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Completed | |||
Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on 5-year Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT05343260] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Active, not recruiting | |||
Clonidine for Tourniquet-related Pain in Children: A Pilot Study[NCT04564430] | Phase 4 | 20 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
Effect of Sevoflurane-induced Postconditioning on the Incidence of Postoperative Cerebral Hyperperfusion Syndrome After Revascularization Surgery in Adult Patients With Moyamoya Disease[NCT02510586] | 152 participants (Anticipated) | Interventional | 2015-08-31 | Not yet recruiting | |||
Effects on Bleeding in Knee Arthroplasty After Ischemic Preconditioning With Sevoflurane[NCT03379103] | 30 participants (Actual) | Interventional | 2018-02-02 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
4 reviews available for sevoflurane and Injury, Ischemia-Reperfusion
Article | Year |
---|---|
Experimental and Clinical Aspects of Sevoflurane Preconditioning and Postconditioning to Alleviate Hepatic Ischemia-Reperfusion Injury: A Scoping Review.
Topics: Humans; Ischemia; Liver Diseases; Reperfusion Injury; Sevoflurane | 2023 |
Molecular Aspects of Volatile Anesthetic-Induced Organ Protection and Its Potential in Kidney Transplantation.
Topics: Anesthetics, Inhalation; Animals; Humans; Isoflurane; Kidney; Kidney Transplantation; Reperfusion In | 2021 |
Emerging graft protective strategies in clinical liver transplantation.
Topics: Anesthetics, Inhalation; Anti-Inflammatory Agents; Desflurane; Graft Rejection; Graft Survival; Huma | 2017 |
Anesthesia for free vascularized tissue transfer.
Topics: Anesthesia; Anesthesia, Conduction; Anesthetics, Inhalation; Hematocrit; Hemodilution; Hemodynamics; | 2009 |
16 trials available for sevoflurane and Injury, Ischemia-Reperfusion
Article | Year |
---|---|
Limb Remote Ischemic Preconditioning Applied During Sevoflurane Anesthesia Does Not Protect the Lungs in Patients Undergoing Adult Heart Valve Surgery.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Aorta; Bronchoalveolar Lavage; Const | 2021 |
Effect of sevoflurane and propofol on tourniquet-induced endothelial damage: a pilot randomized controlled trial for knee-ligament surgery.
Topics: Adult; Endothelium; Glycocalyx; Heparitin Sulfate; Humans; Knee; Ligaments; Pilot Projects; Propofol | 2020 |
Propofol-based anaesthesia versus sevoflurane-based anaesthesia for living donor kidney transplantation: results of the VAPOR-1 randomized controlled trial.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anest | 2017 |
Propofol post-conditioning after temporary clipping reverses oxidative stress in aneurysm surgery.
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Brain; Female; Humans; Intracranial Aneurys | 2019 |
Effects of Different Volatile Anesthetics on Cytokine and Chemokine Production After Ischemia-Reperfusion Injury in Patients Undergoing Living-Donor Kidney Transplant.
Topics: Adult; Anesthetics, Inhalation; Biomarkers; Cytokines; Desflurane; Female; Graft Survival; Humans; I | 2019 |
The comparison of the effects of sevoflurane inhalation anesthesia and intravenous propofol anesthesia on oxidative stress in one lung ventilation.
Topics: Administration, Intravenous; Adolescent; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Doub | 2014 |
The effects of spinal, inhalation, and total intravenous anesthetic techniques on ischemia-reperfusion injury in arthroscopic knee surgery.
Topics: Acetaminophen; Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Spina | 2014 |
Hepatic cytoprotective effect of ischemic and anesthetic preconditioning before liver resection when using intermittent vascular inflow occlusion: a randomized clinical trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Caspase 3; Female; Hepatectomy; Humans; Isc | 2015 |
Comparison of the neuroprotective effects and recovery profiles of isoflurane, sevoflurane and desflurane as neurosurgical pre-conditioning on ischemia/reperfusion cerebral injury.
Topics: Aged; Cerebrovascular Circulation; Desflurane; Female; Hemodynamics; Humans; Isoflurane; Male; Methy | 2015 |
Protective effect of sevoflurane preconditioning on ischemia-reperfusion injury in patients undergoing reconstructive plastic surgery with microsurgical flap, a randomized controlled trial.
Topics: Adult; Anesthetics, Inhalation; Biomarkers; Female; Humans; Ischemic Preconditioning; Mammaplasty; M | 2016 |
A randomized controlled trial on pharmacological preconditioning in liver surgery using a volatile anesthetic.
Topics: Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Colorectal | 2008 |
A randomized controlled trial on pharmacological preconditioning in liver surgery using a volatile anesthetic.
Topics: Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Colorectal | 2008 |
A randomized controlled trial on pharmacological preconditioning in liver surgery using a volatile anesthetic.
Topics: Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Colorectal | 2008 |
A randomized controlled trial on pharmacological preconditioning in liver surgery using a volatile anesthetic.
Topics: Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Colorectal | 2008 |
Protection of pharmacological postconditioning in liver surgery: results of a prospective randomized controlled trial.
Topics: Aged; Anesthetics, Inhalation; Aspartate Aminotransferases; Female; Hepatectomy; Humans; Ischemic Po | 2012 |
Tourniquet-induced ischemia-reperfusion injuries during extremity surgery at children's age: impact of anesthetic chemical structure.
Topics: Adolescent; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Inhalation; Antioxidants; | 2013 |
Sevoflurane inhalation at sedative concentrations provides endothelial protection against ischemia-reperfusion injury in humans.
Topics: Administration, Inhalation; Adult; Anesthetics, Inhalation; CD11b Antigen; Cross-Over Studies; Cytop | 2007 |
The effects of propofol or sevoflurane on free radical production after tourniquet induced ischaemia-reperfusion injury during knee arthroplasty.
Topics: Aged; Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Arthroplasty, Replace | 2007 |
Sevoflurane but not propofol increases interstitial glycolysis metabolites availability during tourniquet-induced ischaemia-reperfusion.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Female; Glucose; | 2008 |
137 other studies available for sevoflurane and Injury, Ischemia-Reperfusion
Article | Year |
---|---|
Sevoflurane protects against cerebral ischemia/reperfusion injury via microrna-30c-5p modulating homeodomain-interacting protein kinase 1.
Topics: Animals; Base Sequence; Brain Ischemia; Cell Line; Disease Models, Animal; Down-Regulation; Glucose; | 2021 |
Role of microRNA‑218‑5p in sevoflurane‑induced protective effects in hepatic ischemia/reperfusion injury mice by regulating GAB2/PI3K/AKT pathway.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Ischemia; Liver; Liver Diseases; Male; Mic | 2022 |
Sevoflurane Offers Neuroprotection in a Cerebral Ischemia/Reperfusion Injury Rat Model Through the E2F1/EZH2/TIMP2 Regulatory Axis.
Topics: Animals; Apoptosis; Brain Ischemia; E2F1 Transcription Factor; Enhancer of Zeste Homolog 2 Protein; | 2022 |
Sevoflurane activates MEF2D-mediated Wnt/β-catenin signaling pathway via microRNA-374b-5p to affect renal ischemia/reperfusion injury.
Topics: Animals; Apoptosis; beta Catenin; Kidney; MEF2 Transcription Factors; Mice; MicroRNAs; Reperfusion I | 2022 |
Ferroptosis involved in sevoflurane-aggravated young rats brain injury induced by liver transplantation.
Topics: Animals; Brain Injuries; Child; Deferoxamine; Ferroptosis; Humans; Iron; Ischemia; Liver; Liver Tran | 2022 |
Sevoflurane postconditioning ameliorates cerebral ischemia-reperfusion injury in rats via TLR4/MyD88/TRAF6 signaling pathway.
Topics: Animals; Brain Ischemia; Myeloid Differentiation Factor 88; Rats; Rats, Sprague-Dawley; Reperfusion | 2022 |
Sevoflurane Preconditioning Downregulates GRIA1 Expression to Attenuate Cerebral Ischemia-Reperfusion-Induced Neuronal Injury.
Topics: Animals; Apoptosis; Brain Ischemia; Cerebral Infarction; Glucose; Neurons; Neuroprotective Agents; O | 2023 |
Sevoflurane participates in the protection of rat renal ischemia-reperfusion injury by down-regulating the expression of TRPM7.
Topics: Animals; bcl-2-Associated X Protein; Caspase 3; Creatinine; Male; Malondialdehyde; Proto-Oncogene Pr | 2023 |
Sevoflurane preconditioning improves neuroinflammation in cerebral ischemia/reperfusion induced rats through ROS-NLRP3 pathway.
Topics: Animals; Brain Ischemia; Caspase 1; Cerebral Infarction; Interleukin-18; Interleukin-6; Neuroinflamm | 2023 |
Effects of fullerene C60 on liver tissue in liver ischemia reperfusion injury in rats undergoing sevoflurane anesthesia.
Topics: Anesthesia; Animals; Female; Ischemia; Liver; Rats; Rats, Wistar; Reperfusion Injury; Sevoflurane; T | 2023 |
[Regulatory T cells are involved in sevoflurane preconditioning-induced mouse brain protection against cerebral ischemia injury].
Topics: Animals; Brain; Brain Ischemia; Ischemic Preconditioning; Mice; Mice, Inbred C57BL; Reperfusion Inju | 2019 |
Effect of sevoflurane pretreatment in relieving liver ischemia/reperfusion-induced pulmonary and hepatic injury.
Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Disease Models, | 2019 |
Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Disease Models, Animal; Interleukin-6; Intestinal Mucos | 2020 |
Sevoflurane attenuates brain damage through inhibiting autophagy and apoptosis in cerebral ischemia‑reperfusion rats.
Topics: Animals; Apoptosis; Cerebral Cortex; Disease Models, Animal; Male; Neurons; Rats; Rats, Sprague-Dawl | 2020 |
Sevoflurane Post-treatment Upregulated miR-203 Expression to Attenuate Cerebral Ischemia-Reperfusion-Induced Neuroinflammation by Targeting MyD88.
Topics: Animals; Brain Ischemia; Drug Delivery Systems; Gene Expression; Inflammation; Male; MicroRNAs; Myel | 2020 |
Specific microRNAs are involved in the reno‑protective effects of sevoflurane preconditioning and ischemic preconditioning against ischemia reperfusion injury in rats.
Topics: Animals; Blotting, Western; Creatinine; Hemodynamics; Ischemic Preconditioning; Male; MicroRNAs; Rat | 2020 |
MicroRNA-153-3p increases autophagy in sevoflurane-preconditioned mice to protect against ischaemic/reperfusion injury after knee arthroplasty.
Topics: Animals; Arthroplasty, Replacement, Knee; Autophagy; Beclin-1; Chondrocytes; Down-Regulation; Humans | 2020 |
A study of optimal concentration range and time window of sevoflurane preconditioning for brain protection in MCAO rats.
Topics: Animals; Brain; Brain Ischemia; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery | 2020 |
Research on mechanism of sevoflurane in alleviating cerebral ischemia-reperfusion injury in rats through JNK signaling pathway.
Topics: Animals; Apoptosis; JNK Mitogen-Activated Protein Kinases; Male; Rats; Rats, Sprague-Dawley; Reperfu | 2020 |
Sevoflurane inhibits neuronal apoptosis and expressions of HIF-1 and HSP70 in brain tissues of rats with cerebral ischemia/reperfusion injury.
Topics: Animals; Apoptosis; Brain; Disease Models, Animal; HSP70 Heat-Shock Proteins; Hypoxia-Inducible Fact | 2020 |
Sevoflurane Preconditioning Confers Delayed Cardioprotection by Upregulating AMP-Activated Protein Kinase Levels to Restore Autophagic Flux in Ischemia-Reperfusion Rat Hearts.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Cardiotonic Agents; China; Ischemic Preconditioni | 2020 |
MicroRNA-203-mediated inhibition of doublecortin underpins cardioprotection conferred by sevoflurane in rats after myocardial ischaemia-reperfusion injury.
Topics: Animals; Antagomirs; Cardiotonic Agents; Disease Models, Animal; Doublecortin Domain Proteins; Doubl | 2020 |
Overexpression of NLRC3 enhanced inhibition effect of sevoflurane on inflammation in an ischaemia reperfusion cell model.
Topics: Animals; Inflammasomes; Inflammation; Intercellular Signaling Peptides and Proteins; NF-kappa B; PC1 | 2020 |
The Effect of Cerium Oxide on Lung Tissue in Lower Extremity Ischemia Reperfusion Injury in Sevoflurane Administered Rats.
Topics: Animals; Cerium; Lower Extremity; Lung; Lung Injury; Oxidative Stress; Rats, Wistar; Reperfusion Inj | 2020 |
Pharmacological preconditioning protects from ischemia/reperfusion-induced apoptosis by modulating Bcl-xL expression through a ROS-dependent mechanism.
Topics: Animals; Apoptosis; bcl-X Protein; Cell Survival; Humans; Hypoglycemic Agents; Metformin; Myocardial | 2021 |
Donor Preconditioning with Inhaled Sevoflurane Mitigates the Effects of Ischemia-Reperfusion Injury in a Swine Model of Lung Transplantation.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Disease Models, Animal; Ischemic Preco | 2021 |
Sevoflurane protects the liver from ischemia-reperfusion injury by regulating Nrf2/HO-1 pathway.
Topics: Animals; Apoptosis; Cell Line; Disease Models, Animal; Heme Oxygenase (Decyclizing); Heme Oxygenase- | 2021 |
Sevoflurane preconditioning activates HGF/Met-mediated autophagy to attenuate hepatic ischemia-reperfusion injury in mice.
Topics: Animals; Apoptosis; Hepatocyte Growth Factor; Hepatocytes; Liver Diseases; Male; Mice; Mice, Inbred | 2021 |
Neuroprotection of sevoflurane against ischemia/reperfusion-induced brain injury through inhibiting GluN2A/GluN2B-PSD-95-MLK3 module.
Topics: Animals; Brain Injuries; MAP Kinase Kinase Kinases; Neuroprotection; Rats; Rats, Sprague-Dawley; Rec | 2021 |
Sevoflurane inhibits the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes via regulating miR-27a-3p-mediated autophagy.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Autophagy; Cell Line; Cell Survival; Down-Regulation; H | 2021 |
Effects of sevoflurane on NF-кB and TNF-α expression in renal ischemia-reperfusion diabetic rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Blood Urea Nitrogen; Diabetes Mellitus, Experimental; I | 2017 |
Sevoflurane protects rat brain endothelial barrier structure and function after hypoxia-reoxygenation injury.
Topics: Animals; Apoptosis; Brain; Cell Membrane Permeability; Cells, Cultured; Endothelium, Vascular; Hypox | 2017 |
Ischemic Preconditioning Produces Comparable Protection Against Hepatic Ischemia/Reperfusion Injury Under Isoflurane and Sevoflurane Anesthesia in Rats.
Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Ischemia; Ischemic Precond | 2017 |
Effect of sevoflurane on the ATPase activity of hippocampal neurons in a rat model of cerebral ischemia-reperfusion injury via the cAMP-PKA signaling pathway.
Topics: Animals; Brain-Derived Neurotrophic Factor; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP- | 2018 |
Experimental ex vivo lung perfusion with sevoflurane: effects on damaged donor lung grafts.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Extracorporeal Circulation; Lung; Lung Tra | 2018 |
Effects of sevoflurane post-conditioning in cerebral ischemia-reperfusion injury via TLR4/NF-κB pathway in rats.
Topics: Animals; Brain Ischemia; Cytokines; Ischemic Postconditioning; Neuroprotective Agents; NF-kappa B; R | 2018 |
Postconditioning with sevoflurane ameliorates spatial learning and memory deficit via attenuating endoplasmic reticulum stress induced neuron apoptosis in a rat model of hemorrhage shock and resuscitation.
Topics: Animals; Apoptosis; Brain Ischemia; CA1 Region, Hippocampal; Disease Models, Animal; Endoplasmic Ret | 2018 |
Impact of Volatile Anesthetic Agents on Early Clinical Outcomes in Liver Transplantation.
Topics: Anesthetics, Inhalation; Desflurane; Female; Graft Survival; Humans; Isoflurane; Liver; Liver Functi | 2018 |
Interaction between anesthetic conditioning and ischemic preconditioning on metabolic function after hepatic ischemia-reperfusion in rabbits.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Disease Models, Animal; Hemodynamics; Ischemic Precond | 2018 |
Sevoflurane postconditioning improves the spatial learning and memory impairments induced by hemorrhagic shock and resuscitation through suppressing IRE1α-caspase-12-mediated endoplasmic reticulum stress pathway.
Topics: Animals; Caspase 12; Endoplasmic Reticulum Stress; Endoribonucleases; Ischemic Postconditioning; Mal | 2018 |
Downregulation of the long noncoding RNA MBNL1-AS1 protects sevoflurane-pretreated mice against ischemia-reperfusion injury by targeting KCNMA1.
Topics: Animals; Apoptosis; Arthroplasty, Replacement, Knee; Cell Cycle; Cell Proliferation; Cyclic GMP; Cyc | 2018 |
Sevoflurane Protects Hepatocytes From Ischemic Injury by Reducing Reactive Oxygen Species Signaling of Hepatic Stellate Cells: Translational Findings Based on a Clinical Trial.
Topics: Antioxidants; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Culture Media, Conditioned; C | 2018 |
Effect of pharmacological preconditioning with sevoflurane during hepatectomy with intermittent portal triad clamping.
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Constriction; Female; Hepatectomy; Humans; | 2019 |
Effect of sevoflurane on hepatic ischemia-reperfusion injury in rats via JAK2-STAT3 pathway.
Topics: Administration, Inhalation; Animals; Cytokines; Disease Models, Animal; Janus Kinase 2; Liver; Liver | 2019 |
Sevoflurane Promotes Regeneration of the Endothelial Glycocalyx by Upregulating Sialyltransferase.
Topics: Anesthetics, Inhalation; Animals; Aorta; beta-D-Galactoside alpha 2-6-Sialyltransferase; Disease Mod | 2019 |
Sevoflurane has postconditioning as well as preconditioning properties against hepatic warm ischemia-reperfusion injury in rats.
Topics: Alanine Transaminase; Animals; Liver; Male; Protoporphyrins; Rats; Rats, Wistar; Reperfusion Injury; | 2019 |
Effect of sevoflurane-based or propofol-based anaesthesia on the incidence of postoperative acute kidney injury: A retrospective propensity score-matched analysis.
Topics: Acute Kidney Injury; Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; C | 2019 |
Sevoflurane prevents miR-181a-induced cerebral ischemia/reperfusion injury.
Topics: 3' Untranslated Regions; Animals; Antagomirs; Apoptosis; Base Sequence; Down-Regulation; Infarction, | 2019 |
Postischemic sevoflurane offers no additional neuroprotective benefit to preischemic dexmedetomidine.
Topics: Actins; Anesthetics, Inhalation; Animals; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; | 2013 |
Preconditioning with sevoflurane ameliorates spatial learning and memory deficit after focal cerebral ischemia-reperfusion in rats.
Topics: Animals; Brain Ischemia; Cholinergic Neurons; Hippocampus; Male; Maze Learning; Memory Disorders; Me | 2013 |
Protective effect of sevoflurane on hepatic ischaemia/reperfusion injury in the rat: A dose-response study.
Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Biomarkers; Cyt | 2013 |
Effects of conditioning with sevoflurane before reperfusion on hippocampal ischemic injury and insulin-like growth factor-1 expression in rats.
Topics: Animals; Hippocampus; Insulin-Like Growth Factor I; Ischemic Postconditioning; JNK Mitogen-Activated | 2013 |
Hypertrophied myocardium is refractory to sevoflurane-induced protection with alteration of reperfusion injury salvage kinase/glycogen synthase kinase 3β signals.
Topics: Animals; Glycogen Synthase Kinase 3; Male; Methyl Ethers; Myocardium; Phosphorylation; Proto-Oncogen | 2013 |
Effects of sevoflurane pretreatment on renal Src and FAK expression in diabetic rats after renal ischemia/reperfusion injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Experim | 2013 |
Activation of K(2)P channel-TREK1 mediates the neuroprotection induced by sevoflurane preconditioning.
Topics: Animals; Brain; Brain Ischemia; Carbon Monoxide; Cell Differentiation; Cell Hypoxia; Cell Survival; | 2014 |
The mechanism of sevoflurane preconditioning-induced protections against small intestinal ischemia reperfusion injury is independent of mast cell in rats.
Topics: Anesthetics, Inhalation; Animals; beta-N-Acetylhexosaminidases; Cromolyn Sodium; Female; Immunoenzym | 2013 |
Effect of sevoflurane on tissue permeability of lung ischemia-reperfusion injury in rats.
Topics: Animals; Lung; Male; Methyl Ethers; Permeability; Protective Agents; Random Allocation; Rats; Rats, | 2014 |
Ischemic versus pharmacologic hepatic preconditioning.
Topics: Anesthetics, Inhalation; Animals; Bilirubin; Biomarkers; C-Reactive Protein; DNA Damage; Ischemic Pr | 2014 |
Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury involving mitochondrial ATP-dependent potassium channel and mitochondrial permeability transition pore.
Topics: Animals; Apoptosis; Brain Edema; Brain Ischemia; Disease Models, Animal; Infarction, Middle Cerebral | 2015 |
Sevoflurane postconditioning attenuates cerebral ischemia-reperfusion injury via protein kinase B/nuclear factor-erythroid 2-related factor 2 pathway activation.
Topics: Animals; Brain Infarction; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Enzyme Inhi | 2014 |
Sevoflurane preconditioning ameliorates neuronal deficits by inhibiting microglial MMP-9 expression after spinal cord ischemia/reperfusion in rats.
Topics: Animals; Apoptosis; Cell Movement; Chemokines; Inflammation Mediators; Male; Matrix Metalloproteinas | 2014 |
Does ischemia-reperfusion injury after solid organ transplantation damage native organs?
Topics: Anesthetics, Inhalation; Animals; Liver; Lung; Methyl Ethers; Reperfusion Injury; Sevoflurane | 2014 |
Sevoflurane prevents liver inflammatory response induced by lung ischemia-reperfusion.
Topics: Anesthetics, Inhalation; Animals; C-Reactive Protein; Caspase 3; Chemokine CCL2; Ferritins; Hemodyna | 2014 |
Isoflurane but not sevoflurane or desflurane aggravates injury to neurons in vitro and in vivo via p75NTR-NF-ĸB activation.
Topics: Anesthetics, Inhalation; Animals; Binding Sites; Cell Death; Cell Hypoxia; Cell Line, Tumor; Desflur | 2014 |
Neuroprotection induced by sevoflurane-delayed post-conditioning is attributable to increased phosphorylation of mitochondrial GSK-3β through the PI3K/Akt survival pathway.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Glycogen Synthase Kinase 3; Glycogen Synthase Kina | 2015 |
Sevoflurane protects against intestinal ischemia-reperfusion injury partly by phosphatidylinositol 3 kinases/Akt pathway in rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Blood Gas Analysis; Drug Evaluation, Preclinical; Hemod | 2015 |
Neuroprotection of Sevoflurane Against Ischemia/Reperfusion-Induced Brain Injury Through Inhibiting JNK3/Caspase-3 by Enhancing Akt Signaling Pathway.
Topics: Androstadienes; Animals; Apoptosis; Brain Injuries; CA1 Region, Hippocampal; Caspase 3; Chromones; E | 2016 |
Sevoflurane ameliorates intestinal ischemia-reperfusion-induced lung injury by inhibiting the synergistic action between mast cell activation and oxidative stress.
Topics: Acetophenones; Acute Lung Injury; Anesthetics, Inhalation; Animals; Antioxidants; Cell Degranulation | 2015 |
Sevoflurane preconditioning improving cerebral focal ischemia-reperfusion damage in a rat model via PI3K/Akt signaling pathway.
Topics: Animals; Antioxidants; Apoptosis; Brain Ischemia; Gene Expression Regulation; Methyl Ethers; Oncogen | 2015 |
Effects of sevoflurane on tight junction protein expression and PKC-α translocation after pulmonary ischemia-reperfusion injury.
Topics: Anesthetics, Inhalation; Animals; Capillary Permeability; Gene Expression Regulation; Lung; Lung Dis | 2015 |
Sevoflurane Preconditioning Reduces Intestinal Ischemia-Reperfusion Injury: Role of Protein Kinase C and Mitochondrial ATP-Sensitive Potassium Channel.
Topics: Animals; Benzophenanthridines; Intestinal Mucosa; Intestines; Ischemic Preconditioning; KATP Channel | 2015 |
Mechanisms of the beneficial effect of sevoflurane in liver ischemia/reperfusion injury.
Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Capillary Perme | 2015 |
The effect of propofol and sevoflurane on antioxidants and proinflammatory cytokines in a porcine ischemia-reperfusion model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Methyl Ethers; Myocytes, Sm | 2016 |
Sevoflurane pretreatment enhance HIF-2α expression in mice after renal ischemia/reperfusion injury.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Basic Helix-Loop-Helix Transcription Factors | 2015 |
Molecular studies of the immunological effects of the sevoflurane preconditioning in the liver and lung in a rat model of liver ischemia/reperfusion injury.
Topics: Animals; Apoptosis; Complement Activation; Complement C3; Intercellular Adhesion Molecule-1; Ischemi | 2016 |
Protective effects of sevoflurane in hepatic ischemia-reperfusion injury.
Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Endothelium; Fe | 2016 |
The Effects of Two Anesthetics, Propofol and Sevoflurane, on Liver Ischemia/Reperfusion Injury.
Topics: Animals; bcl-2-Associated X Protein; Disease Models, Animal; Interleukin-1; Interleukin-6; Liver; Ma | 2016 |
Propofol but not sevoflurane prevents mitochondrial dysfunction and oxidative stress by limiting HIF-1α activation in hepatic ischemia/reperfusion injury.
Topics: Anesthetics; Animals; Apoptosis; Free Radicals; Humans; Hydrogen Peroxide; Hypoxia-Inducible Factor | 2016 |
Protective effects of estrogen combined with sevoflurane in an experimental model of cerebral infarction and focal cerebral ischemia-reperfusion injury.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Estrogens; Female; Infarction, Middle Cerebral Artery; | 2016 |
Sevoflurane anesthetic preconditioning protects the lung endothelial glycocalyx from ischemia reperfusion injury in an experimental lung autotransplant model.
Topics: Anesthetics; Animals; Glycocalyx; Intercellular Adhesion Molecule-1; Lung; Methyl Ethers; One-Lung V | 2016 |
Sevoflurane Postconditioning Reduces Apoptosis by Activating the JAK-STAT Pathway After Transient Global Cerebral Ischemia in Rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Disease Models, Animal; Ischemic Attack, Transient; Jan | 2017 |
Adenosine Receptor Adora2b Plays a Mechanistic Role in the Protective Effect of the Volatile Anesthetic Sevoflurane during Liver Ischemia/Reperfusion.
Topics: Adult; Anesthetics, Inhalation; Animals; Disease Models, Animal; Humans; Liver; Liver Diseases; Meth | 2016 |
Anti-inflammatory signaling during ex vivo liver perfusion improves the preservation of pig liver grafts before transplantation.
Topics: Acetylcysteine; Allografts; Alprostadil; Animals; Anti-Inflammatory Agents; Aspartate Aminotransfera | 2016 |
High glucose concentration abrogates sevoflurane post-conditioning cardioprotection by advancing mitochondrial fission but dynamin-related protein 1 inhibitor restores these effects.
Topics: Animals; Cell Survival; Cells, Cultured; Disease Models, Animal; Dynamins; Glucose; Hyperglycemia; I | 2017 |
Postconditioning with sevoflurane ameliorates spatial learning and memory deficit after hemorrhage shock and resuscitation in rats.
Topics: Animals; Biomarkers; Choline O-Acetyltransferase; Cholinergic Neurons; Hippocampus; Ischemic Postcon | 2016 |
Kelch-like ECH-associated Protein 1-dependent Nuclear Factor-E2-related Factor 2 Activation in Relation to Antioxidation Induced by Sevoflurane Preconditioning.
Topics: Anesthetics, Inhalation; Animals; Antioxidants; Disease Models, Animal; Kelch-Like ECH-Associated Pr | 2017 |
Sevoflurane Attenuates Ischemia-Reperfusion Injury in a Rat Lung Transplantation Model.
Topics: Animals; Ischemic Postconditioning; Ischemic Preconditioning; Lung; Lung Injury; Lung Transplantatio | 2017 |
Pharmacological postconditioning with sevoflurane activates PI3K/AKT signaling and attenuates cardiopulmonary bypass-induced lung injury in dog.
Topics: Animals; Cardiopulmonary Bypass; Dogs; Lung Injury; Methyl Ethers; Phosphatidylinositol 3-Kinases; P | 2017 |
Induction of heat shock protein 70 and preconditioning by sevoflurane: a potent protective interaction against myocardial ischemia-reperfusion injury.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Heart; HSP70 Heat-Shock Proteins; Humans; Ischemic Prec | 2008 |
[Effect of sevoflurane postconditioning on spinal cord ischemia reperfusion injury via the release of oxygen free radicals in rabbits].
Topics: Animals; Disease Models, Animal; Female; Methyl Ethers; Platelet Aggregation Inhibitors; Rabbits; Re | 2008 |
[Sevoflurane preconditioning induced delayed neuroprotection against focal cerebral ischemia in rats].
Topics: Animals; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Interleukin-1beta; Ischemic Pr | 2009 |
Sevoflurane postconditioning converts persistent ventricular fibrillation into regular rhythm.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Hemodynamics; Ischemic Preconditioning, My | 2009 |
[Effects of sevoflurane postconditioning on renal ischemia-reperfusion injury: experiment with rats].
Topics: Animals; Disease Models, Animal; Kidney Diseases; Male; Methyl Ethers; Rats; Rats, Sprague-Dawley; R | 2009 |
Sevoflurane postconditioning protects isolated rat hearts against ischemia-reperfusion injury: the role of radical oxygen species, extracellular signal-related kinases 1/2 and mitochondrial permeability transition pore.
Topics: Animals; Hemodynamics; In Vitro Techniques; Male; Malondialdehyde; MAP Kinase Kinase 2; Methyl Ether | 2010 |
Sevoflurane preconditioning induces rapid ischemic tolerance against spinal cord ischemia/reperfusion through activation of extracellular signal-regulated kinase in rabbits.
Topics: Anesthetics, Inhalation; Animals; Aorta, Abdominal; Apoptosis; Butadienes; Cell Survival; Constricti | 2009 |
Sevoflurane postconditioning protects chronically-infarcted rat hearts against ischemia-reperfusion injury by activation of pro-survival kinases and inhibition of mitochondrial permeability transition pore opening upon reperfusion.
Topics: Anesthetics, Inhalation; Animals; Blotting, Western; Enzyme Activation; Male; Methyl Ethers; Mitocho | 2009 |
Cerebral pial vascular changes under propofol or sevoflurane anesthesia during global cerebral ischemia and reperfusion in rabbits.
Topics: Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Arterioles; Blo | 2010 |
[Protective effects of sevoflurane preconditioning on cerebral ischemia-reperfusion injury in rats].
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Disease Models, Animal; Ischemic Preconditioning; Male; M | 2009 |
Sevoflurane postconditioning prevents activation of caspase 3 and 9 through antiapoptotic signaling after myocardial ischemia-reperfusion.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Blotting, Western; Caspase 3; Caspase 9; Chromones; Enz | 2010 |
Sevoflurane postconditioning attenuates spinal cord reperfusion injury through free radicals-mediated up-regulation of antioxidant enzymes in rabbits.
Topics: Animals; Antioxidants; Aorta; Catalase; Constriction; Free Radicals; Ischemic Postconditioning; Male | 2011 |
Attenuation of ischemia-reperfusion injury by sevoflurane postconditioning involves protein kinase B and glycogen synthase kinase 3 beta activation in isolated rat hearts.
Topics: Animals; Blotting, Western; Cytochromes c; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen S | 2010 |
Effects of sevoflurane preconditioning and postconditioning on rat myocardial stunning in ischemic reperfusion injury.
Topics: Anesthetics, Inhalation; Animals; Heart; Hemodynamics; Humans; Ischemic Preconditioning, Myocardial; | 2010 |
[Delayed neuroprotective effect of sevoflurane on the expression of NF-kappaB following transient focal ischemia-reperfusion in rats].
Topics: Animals; Ischemic Attack, Transient; Male; Methyl Ethers; Neuroprotective Agents; NF-kappa B; Random | 2010 |
Sevoflurane postconditioning protects isolated rat hearts against ischemia-reperfusion injury.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Heart; Male; Methyl Ethers; Random Allocation; Rats; Ra | 2010 |
Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury via PI3K/Akt pathway.
Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Brain Ischemia; Immunohistochemistry; I | 2010 |
Volatile anesthetics might be more beneficial than propofol for postoperative liver function in cirrhotic patients receiving hepatectomy.
Topics: Anesthetics, Inhalation; Desflurane; Heme Oxygenase (Decyclizing); Hepatectomy; Humans; Hypoxia-Indu | 2010 |
Sevoflurane postconditioning ameliorates oxygen-glucose deprivation-reperfusion injury in the rat hippocampus.
Topics: Amino Acids; Anesthetics, Inhalation; Animals; Coloring Agents; Electrophysiological Phenomena; Evok | 2011 |
[Neuroprotection of sevoflurane against the ischemia injury in hippocampal slices of rat].
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Excitatory Amino Acid Antagonists; Hippocampus; In | 2008 |
Enhanced glucose uptake via GLUT4 fuels recovery from calcium overload after ischaemia-reperfusion injury in sevoflurane- but not propofol-treated hearts.
Topics: AMP-Activated Protein Kinase Kinases; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Bl | 2011 |
Delayed preconditioning by sevoflurane elicits changes in the mitochondrial proteome in ischemia-reperfused rat hearts.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Blotting, Western; Electrophoresis, Gel, T | 2011 |
Hypothermia and anesthetic postconditioning influence the expression and activity of small intestinal proteins possibly involved in ischemia/reperfusion-mediated events following cardiopulmonary resuscitation.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Biomarkers; Blotting, Western; Cardiopulmo | 2012 |
Sevoflurane reduces leukocyte and platelet adhesion after ischemia-reperfusion by protecting the endothelial glycocalyx.
Topics: Anesthetics, Inhalation; Animals; Cell Adhesion; Coronary Circulation; Edema; Endothelium; Flow Cyto | 2011 |
The effects of anesthetic preconditioning with sevoflurane in an experimental lung autotransplant model in pigs.
Topics: Anesthetics, Inhalation; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Cytoprotection | 2011 |
Inhibition of sevoflurane postconditioning against cerebral ischemia reperfusion-induced oxidative injury in rats.
Topics: Animals; Brain; Glutathione; Infarction, Middle Cerebral Artery; Inflammation Mediators; Interleukin | 2011 |
Sevoflurane-induced delayed neuroprotection involves mitoK(ATP) channel opening and PKC ε activation.
Topics: Animals; Enzyme Activation; Infarction, Middle Cerebral Artery; Ion Channel Gating; Ischemic Precond | 2012 |
Ischemia-reperfusion-induced unmeasured anion generation and glycocalyx shedding: sevoflurane versus propofol anesthesia.
Topics: Acid-Base Equilibrium; Anesthetics; Animals; Capillary Permeability; Disease Models, Animal; Endothe | 2012 |
Sevoflurane preconditioning improves mitochondrial function and long-term neurologic sequelae after transient cerebral ischemia: role of mitochondrial permeability transition.
Topics: Animals; Brain; Disease Models, Animal; Ischemic Attack, Transient; Ischemic Preconditioning; Methyl | 2012 |
Volatile anesthetics reduce invasion of colorectal cancer cells through down-regulation of matrix metalloproteinase-9.
Topics: Anesthetics, Inhalation; Colorectal Neoplasms; Desflurane; Down-Regulation; Enzyme-Linked Immunosorb | 2012 |
Volatile anesthetics reduce invasion of colorectal cancer cells through down-regulation of matrix metalloproteinase-9.
Topics: Anesthetics, Inhalation; Colorectal Neoplasms; Desflurane; Down-Regulation; Enzyme-Linked Immunosorb | 2012 |
Volatile anesthetics reduce invasion of colorectal cancer cells through down-regulation of matrix metalloproteinase-9.
Topics: Anesthetics, Inhalation; Colorectal Neoplasms; Desflurane; Down-Regulation; Enzyme-Linked Immunosorb | 2012 |
Volatile anesthetics reduce invasion of colorectal cancer cells through down-regulation of matrix metalloproteinase-9.
Topics: Anesthetics, Inhalation; Colorectal Neoplasms; Desflurane; Down-Regulation; Enzyme-Linked Immunosorb | 2012 |
"What does not kill you makes you stronger".
Topics: Animals; Ischemic Attack, Transient; Ischemic Preconditioning; Methyl Ethers; Mitochondrial Membrane | 2012 |
Sevoflurane postconditioning alleviates action potential duration shortening and L-type calcium current suppression induced by ischemia/reperfusion injury in rat epicardial myocytes.
Topics: Action Potentials; Animals; Calcium; Electrocardiography; Methyl Ethers; Patch-Clamp Techniques; Per | 2012 |
Does pharmacological conditioning with the volatile anaesthetic sevoflurane offer protection in liver surgery?
Topics: Administration, Inhalation; Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Anesthetics, | 2012 |
Mechanisms of sevoflurane-induced myocardial preconditioning in isolated human right atria in vitro.
Topics: Aged; Anesthetics, Inhalation; ATP-Binding Cassette Transporters; Benzamides; Decanoic Acids; Heart | 2003 |
Sevoflurane-induced preconditioning protects against cerebral ischemic neuronal damage in rats.
Topics: Action Potentials; Anesthetics, Inhalation; Animals; Brain Ischemia; Cell Death; Disease Models, Ani | 2005 |
Improved mitochondrial bioenergetics by anesthetic preconditioning during and after 2 hours of 27 degrees C ischemia in isolated hearts.
Topics: Anesthetics; Anesthetics, Inhalation; Animals; ATP-Binding Cassette Transporters; Blood Pressure; Co | 2005 |
Effect of sevoflurane preconditioning on ischaemia/reperfusion injury in the rat kidney in vivo.
Topics: Animals; Ischemic Preconditioning; Kidney; Male; Methyl Ethers; Rats; Rats, Wistar; Reperfusion Inju | 2006 |
Anesthetic preconditioning with sevoflurane does not protect the spinal cord after an ischemic-reperfusion injury in the rat.
Topics: Anesthetics, Inhalation; Animals; Male; Methyl Ethers; Motor Skills; Rats; Rats, Sprague-Dawley; Rep | 2006 |
The long-term effect of sevoflurane on neuronal cell damage and expression of apoptotic factors after cerebral ischemia and reperfusion in rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis Regulatory Proteins; Blood Flow Velocity; Brain Ischemia | 2006 |
Effects of sevoflurane and propofol on ischaemia-reperfusion injury after thoracic-aortic occlusion in pigs.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Aortic Aneurysm, Thoracic; Blood Pressur | 2007 |
Hepatic energy metabolism and the differential protective effects of sevoflurane and isoflurane anesthesia in a rat hepatic ischemia-reperfusion injury model.
Topics: Adenosine Triphosphate; Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotrans | 2008 |
Preconditioning, but not postconditioning, with Sevoflurane reduces pulmonary neutrophil accumulation after lower body ischaemia/reperfusion injury in rats.
Topics: Anesthetics, Inhalation; Animals; Aorta; Cell Movement; Constriction; Ischemic Preconditioning; Lapa | 2008 |
Sevoflurane protects against renal ischemia and reperfusion injury in mice via the transforming growth factor-beta1 pathway.
Topics: Anesthetics, Inhalation; Animals; Cells, Cultured; Kidney Diseases; Kidney Medulla; Methyl Ethers; M | 2008 |
Lung injury following thoracic aortic occlusion: comparison of sevoflurane and propofol anaesthesia.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Aorta, Thoracic; Arterial Oc | 2008 |
Effects of halothane, isoflurane and sevoflurane on ischemia-reperfusion injury in the perfused liver of fasted rats.
Topics: Anesthetics, Inhalation; Animals; Ethers; Halothane; Ischemia; Isoflurane; L-Lactate Dehydrogenase; | 1996 |
Halothane, isoflurane, and sevoflurane reduce postischemic adhesion of neutrophils in the coronary system.
Topics: Anesthetics, Inhalation; Animals; Cell Adhesion; Cells, Cultured; Coronary Vessels; Endothelium, Vas | 1997 |
Isoflurane-sevoflurane adminstration before ischemia attenuates ischemia-reperfusion-induced injury in isolated rat lungs.
Topics: Anesthetics, Inhalation; Animals; Capillary Permeability; In Vitro Techniques; Isoflurane; L-Lactate | 2000 |
Ischemic and anesthetic preconditioning reduces cytosolic [Ca2+] and improves Ca(2+) responses in intact hearts.
Topics: Anesthetics, Inhalation; Animals; Calcium; Cytosol; Diastole; Guinea Pigs; Heart; Ischemic Precondit | 2001 |
Anesthetic preconditioning: triggering role of reactive oxygen and nitrogen species in isolated hearts.
Topics: Anesthetics; Animals; Coronary Circulation; Enzyme Inhibitors; Guinea Pigs; Heart; In Vitro Techniqu | 2002 |