sevoflurane has been researched along with Huntington Disease in 3 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with Huntington's disease develop a progressive but variable dementia." | 2.40 | Huntington's disease: review and anesthetic case management. ( Cangemi, CF; Miller, RJ, 1998) |
| "Isoflurane is known to increase β-amyloid aggregation and neuronal damage." | 1.37 | The common inhaled anesthetic isoflurane increases aggregation of huntingtin and alters calcium homeostasis in a cell model of Huntington's disease. ( Eckenhoff, MF; Liang, G; Wang, Q; Wang, S; Wei, H; Yang, H, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Q | 1 |
| Liang, G | 1 |
| Yang, H | 1 |
| Wang, S | 1 |
| Eckenhoff, MF | 1 |
| Wei, H | 1 |
| Cangemi, CF | 1 |
| Miller, RJ | 1 |
| Nagele, P | 1 |
| Hammerle, AF | 1 |
1 review available for sevoflurane and Huntington Disease
| Article | Year |
|---|---|
Huntington's disease: review and anesthetic case management.
Topics: Aged; Analgesics, Opioid; Anesthesia, Dental; Anesthesia, General; Anesthetics, Inhalation; Anesthet | 1998 |
2 other studies available for sevoflurane and Huntington Disease
| Article | Year |
|---|---|
The common inhaled anesthetic isoflurane increases aggregation of huntingtin and alters calcium homeostasis in a cell model of Huntington's disease.
Topics: Anesthetics, Inhalation; Animals; Calcium; Cell Survival; Cells, Cultured; Corpus Striatum; Desflura | 2011 |
Sevoflurane and mivacurium in a patient with Huntington's chorea.
Topics: Adolescent; Anesthetics, Inhalation; Appendectomy; Female; Humans; Huntington Disease; Isoquinolines | 2000 |