Page last updated: 2024-11-04

sevoflurane and Hemorrhage, Uterine

sevoflurane has been researched along with Hemorrhage, Uterine in 2 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Research Excerpts

Excerpt	Relevance	Reference
"In a prospective randomised study 52 ASA I patients scheduled for ambulatory pregnancy termination were premedicated with lorazepam and received alfentanil prior to anaesthesia induction with propofol (group P, n = 26) or with sevoflurane 8% (group S, n = 26) using the single breath vital capacity technique."	5.08	Comparison of sevoflurane and propofol for ambulatory anaesthesia in gynaecological surgery. ( Feiss, P; Lahrimi, A; Nathan, N; Peyclit, A, 1998)
"Operating conditions, recovery and postoperative nausea and vomiting (PONV) were assessed."	2.69	Comparison of sevoflurane-nitrous oxide and propofol-alfentanil-nitrous oxide anaesthesia for minor gynaecological surgery. ( Korttila, K; Nelskylä, K; Yli-Hankala, A, 1999)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Nathan, N	1
Peyclit, A	1
Lahrimi, A	1
Feiss, P	1
Nelskylä, K	1
Korttila, K	1
Yli-Hankala, A	1

Clinical Trials (1)

Trial Overview

Trial			Phase	Enrollment	Study Type	Start Date	Status
Sevoflurane as an Anesthetic During Dilation and Evacuation Procedures: Does it Increase Blood Loss and Interventions for Blood Loss and Why Do Anesthesiologists Choose to Use It?[NCT01048658]			Phase 4	160 participants (Actual)	Interventional	2009-09-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Experiencing Side Effects (Nausea, Dizziness)

(NCT01048658)
Timeframe: Post-procedure, within 30 minutes

Intervention	Participants (Count of Participants)
Sevoflurane	13
No Sevoflurane	11

Number of Participants Needing Intervention to Treat Blood Loss (a Composite of Use of Uterotonics, Re-aspiration, and Bimanual Massage)

Provider report for need to intervene due to blood loss (yes/no) (NCT01048658)
Timeframe: At time of uterine evacuation and immediately post-operatively, an average of 7.1 minutes

Intervention	Participants (Count of Participants)
Sevoflurane	20
No Sevoflurane	13

Number of Participants With Estimated Blood Loss Greater Than 300 mL (Yes/no)

Procedural blood loss greater than 300 mL. Blood loss was measured in a standardized fashion (amniotic fluid was discarded, blood was separated from tissue, and all gauze surgical drapes weighed). (NCT01048658)
Timeframe: At time of uterine evacuation, an average of 7.1 minutes

Intervention	Participants (Count of Participants)
Sevoflurane	12
No Sevoflurane	6

Procedure Time: T-test (Time of Speculum Placement to Time Speculum Removed)

Length of procedure from time of speculum placement to time of speculum removal, in minutes. (NCT01048658)
Timeframe: Time of speculum place to time of speculum removal, an average of 7.1 minutes

Intervention	minutes (Mean)
Sevoflurane	7.0
No Sevoflurane	7.3

Patient and Provider Satisfaction With Anesthesia

Scores reported on 10-cm Visual Analog Scale (VAS anchors: 0= not satisfied at all, 10= completely satisfied) . Reported as mean +/- standard deviation. Subjects and providers were blinded to anesthesia method. Subjects and providers completed post-operative questionnaire within 30 minutes of procedure completion. (NCT01048658)
Timeframe: Post-procedure, within 30 minutes

Intervention	cm (Mean)
	Provider Satisfaction	Patient Satisfaction
No Sevoflurane	9.3	8.2
Sevoflurane	9.4	8.4

Trials

2 trials available for sevoflurane and Hemorrhage, Uterine

Article	Year
Comparison of sevoflurane and propofol for ambulatory anaesthesia in gynaecological surgery. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:12 Topics: Abortion, Induced; Activities of Daily Living; Adult; Ambulatory Surgical Procedures; Anesthesia, Ge	1998
Comparison of sevoflurane-nitrous oxide and propofol-alfentanil-nitrous oxide anaesthesia for minor gynaecological surgery. British journal of anaesthesia, 1999, Volume: 83, Issue:4 Topics: Adult; Alfentanil; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Inhalation; Anest	1999