sevoflurane has been researched along with Glioma in 24 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This randomized equivalency trial will primarily compare the impacts of sevoflurane-remifentanil and propofol-remifentanil anesthesia on short-term postoperative neurologic function in patients with supratentorial gliomas undergoing craniotomy." | 9.34 | Sevoflurane versus PRopofol combined with Remifentanil anesthesia Impact on postoperative Neurologic function in supratentorial Gliomas (SPRING): protocol for a randomized controlled trial. ( Bebawy, JF; Dong, J; Han, R; Li, J; Li, Y; Lin, N; Liu, X; Nie, L; Peng, Y; Xing, Y; Zeng, M; Zhang, M, 2020) |
| "Sevoflurane (SEV) is a common anesthetic to inhibit glioma progression." | 8.12 | Sevoflurane represses the progression of glioma by the regulation of circ_0037655/miR-130a-5p/RPN2 axis. ( Huang, G; Li, Y; Liu, Z; Xie, B; Zhu, J, 2022) |
| "Sevoflurane alleviated proliferation, migration and invasion, but enhanced apoptosis of glioma cells through regulating circ_VCAN/miR-146b-5p/NFIB axis." | 8.12 | Sevoflurane inhibits the malignant phenotypes of glioma through regulating miR-146b-5p/NFIB axis. ( Cheng, G; Feng, Y; Li, X; Pan, H; Qu, H; Quan, L; Shi, X; Wang, H; Yang, A; Ye, J, 2022) |
| "Sevoflurane has been reported to have anti-tumorigenic effects in glioma." | 8.02 | Sevoflurane impedes glioma progression via regulating circ_0000215/miR-1200/NCR3LG1 axis. ( Gao, B; Gao, R; Zhao, Z; Zong, X, 2021) |
| "Sevoflurane is a common inhalational anesthetic, which has been revealed to have anticancer effect in glioma." | 8.02 | Sevoflurane suppresses glioma tumorigenesis via regulating circ_0079593/miR-633/ROCK1 axis. ( Cheng, J; Cheng, S, 2021) |
| "Effects of sevoflurane on cell viability, proliferation and invasion ability of glioma cells as well as tumor growth in vivo were assessed." | 7.96 | Sevoflurane modulates the cancer stem cell-like properties and mitochondrial membrane potential of glioma via Ca ( Dong, X; Han, XC; Li, KH; Xing, QZ; Zhang, L; Zhang, YJ, 2020) |
| "Sevoflurane (sev) was employed to treat glioma cells." | 7.96 | Sevoflurane impedes the progression of glioma through modulating the circular RNA has_circ_0012129/miR-761/TGIF2 axis. ( Kang, LY; Liu, WW; Tang, L; Wang, W; Wei, WT; Xia, R; Xu, W; Xue, R; Zheng, JW, 2020) |
| " Volatile anesthetic sevoflurane inhibits the migration and invasion of multiple cancer cell lines; however, its effects on glioma cells are unclear." | 7.83 | Sevoflurane inhibits the migration and invasion of glioma cells by upregulating microRNA-637. ( Guo, Y; Huang, B; Li, D; Li, X; Yi, W; Zhang, Y, 2016) |
| " This study investigates the effect of sevoflurane on glioma stem cells (GSCs) in vitro and the underlying molecular mechanisms in this process." | 7.81 | Sevoflurane promotes the expansion of glioma stem cells through activation of hypoxia-inducible factors in vitro. ( Chen, QS; Liu, L; Shi, QY; Yan, M; Yu, LN; Zhang, FJ; Zhang, SJ, 2015) |
| " The aim of this study was to evaluate the effect of propofol on the apoptosis, Aβ accumulation, and inflammation induced by sevoflurane in human neuroglioma cells." | 7.81 | Anesthetic Propofol Attenuates Apoptosis, Aβ Accumulation, and Inflammation Induced by Sevoflurane Through NF-κB Pathway in Human Neuroglioma Cells. ( Guo, S; Guo, Y; Jian, L; Tian, Y, 2015) |
| "H4 human neuroglioma cells (H4 cells), and mouse primary neurones and microglia were treated with 2% isoflurane or 4." | 7.79 | Isoflurane and sevoflurane increase interleukin-6 levels through the nuclear factor-kappa B pathway in neuroglioma cells. ( Dong, Y; Xie, Z; Yang, L; Zhang, J; Zhang, L; Zhang, Y, 2013) |
| "Sevoflurane (Sev) has been reported to inhibit cancer development, and sevoflurane treatment in cancers is implicated with the deregulation of specific non-coding RNAs (ncRNAs)." | 5.62 | Sevoflurane blocks glioma malignant development by upregulating circRELN through circRELN-mediated miR-1290/RORA axis. ( Kang, X; Li, H; Zhang, Z, 2021) |
| "Glioma is the most common brain malignancy and surgical resection is the primary option for patient with glioma." | 5.56 | Sevoflurane inhibits migration and invasion of glioma cells via regulating miR-34a-5p/MMP-2 axis. ( Li, Z; Xing, F; Yuan, J; Zhang, W; Zhao, H, 2020) |
| "Malignant glioma is the most common primary malignancy in the brain." | 5.56 | Sevoflurane Inhibits Glioma Cells Proliferation and Metastasis through miRNA-124-3p/ROCK1 Axis. ( Gao, C; He, XF; Meng, ZX; Shen, J, 2020) |
| "Sevoflurane is a new type of inhalation anesthetic used widely in the clinic." | 5.51 | Sevoflurane downregulates insulin-like growth factor-1 to inhibit cell proliferation, invasion and trigger apoptosis in glioma through the PI3K/AKT signaling pathway. ( Gao, C; He, XF; Shen, J; Xu, QR; Xu, YJ, 2019) |
| "Post-operative cerebral edema is a threat for patients performed gliomas resection." | 5.42 | Effects of propofol and sevoflurane on aquaporin-4 and aquaporin-9 expression in patients performed gliomas resection. ( Chang, FF; Dong, H; Lu, SJ; Qian, H; Song, CY; Yang, WC; Yue, ZY; Zhang, R; Zhou, LJ, 2015) |
| "This randomized equivalency trial will primarily compare the impacts of sevoflurane-remifentanil and propofol-remifentanil anesthesia on short-term postoperative neurologic function in patients with supratentorial gliomas undergoing craniotomy." | 5.34 | Sevoflurane versus PRopofol combined with Remifentanil anesthesia Impact on postoperative Neurologic function in supratentorial Gliomas (SPRING): protocol for a randomized controlled trial. ( Bebawy, JF; Dong, J; Han, R; Li, J; Li, Y; Lin, N; Liu, X; Nie, L; Peng, Y; Xing, Y; Zeng, M; Zhang, M, 2020) |
| "Sevoflurane (SEV) is a common anesthetic to inhibit glioma progression." | 4.12 | Sevoflurane represses the progression of glioma by the regulation of circ_0037655/miR-130a-5p/RPN2 axis. ( Huang, G; Li, Y; Liu, Z; Xie, B; Zhu, J, 2022) |
| "Sevoflurane alleviated proliferation, migration and invasion, but enhanced apoptosis of glioma cells through regulating circ_VCAN/miR-146b-5p/NFIB axis." | 4.12 | Sevoflurane inhibits the malignant phenotypes of glioma through regulating miR-146b-5p/NFIB axis. ( Cheng, G; Feng, Y; Li, X; Pan, H; Qu, H; Quan, L; Shi, X; Wang, H; Yang, A; Ye, J, 2022) |
| "Sevoflurane has been reported to have anti-tumorigenic effects in glioma." | 4.02 | Sevoflurane impedes glioma progression via regulating circ_0000215/miR-1200/NCR3LG1 axis. ( Gao, B; Gao, R; Zhao, Z; Zong, X, 2021) |
| "Sevoflurane is a common inhalational anesthetic, which has been revealed to have anticancer effect in glioma." | 4.02 | Sevoflurane suppresses glioma tumorigenesis via regulating circ_0079593/miR-633/ROCK1 axis. ( Cheng, J; Cheng, S, 2021) |
| "Effects of sevoflurane on cell viability, proliferation and invasion ability of glioma cells as well as tumor growth in vivo were assessed." | 3.96 | Sevoflurane modulates the cancer stem cell-like properties and mitochondrial membrane potential of glioma via Ca ( Dong, X; Han, XC; Li, KH; Xing, QZ; Zhang, L; Zhang, YJ, 2020) |
| "Sevoflurane (sev) was employed to treat glioma cells." | 3.96 | Sevoflurane impedes the progression of glioma through modulating the circular RNA has_circ_0012129/miR-761/TGIF2 axis. ( Kang, LY; Liu, WW; Tang, L; Wang, W; Wei, WT; Xia, R; Xu, W; Xue, R; Zheng, JW, 2020) |
| " Volatile anesthetic sevoflurane inhibits the migration and invasion of multiple cancer cell lines; however, its effects on glioma cells are unclear." | 3.83 | Sevoflurane inhibits the migration and invasion of glioma cells by upregulating microRNA-637. ( Guo, Y; Huang, B; Li, D; Li, X; Yi, W; Zhang, Y, 2016) |
| " This study investigates the effect of sevoflurane on glioma stem cells (GSCs) in vitro and the underlying molecular mechanisms in this process." | 3.81 | Sevoflurane promotes the expansion of glioma stem cells through activation of hypoxia-inducible factors in vitro. ( Chen, QS; Liu, L; Shi, QY; Yan, M; Yu, LN; Zhang, FJ; Zhang, SJ, 2015) |
| " The aim of this study was to evaluate the effect of propofol on the apoptosis, Aβ accumulation, and inflammation induced by sevoflurane in human neuroglioma cells." | 3.81 | Anesthetic Propofol Attenuates Apoptosis, Aβ Accumulation, and Inflammation Induced by Sevoflurane Through NF-κB Pathway in Human Neuroglioma Cells. ( Guo, S; Guo, Y; Jian, L; Tian, Y, 2015) |
| "H4 human neuroglioma cells (H4 cells), and mouse primary neurones and microglia were treated with 2% isoflurane or 4." | 3.79 | Isoflurane and sevoflurane increase interleukin-6 levels through the nuclear factor-kappa B pathway in neuroglioma cells. ( Dong, Y; Xie, Z; Yang, L; Zhang, J; Zhang, L; Zhang, Y, 2013) |
| "Sevoflurane (Sev) has been reported to inhibit cancer development, and sevoflurane treatment in cancers is implicated with the deregulation of specific non-coding RNAs (ncRNAs)." | 1.62 | Sevoflurane blocks glioma malignant development by upregulating circRELN through circRELN-mediated miR-1290/RORA axis. ( Kang, X; Li, H; Zhang, Z, 2021) |
| "Glioma is the most common brain malignancy and surgical resection is the primary option for patient with glioma." | 1.56 | Sevoflurane inhibits migration and invasion of glioma cells via regulating miR-34a-5p/MMP-2 axis. ( Li, Z; Xing, F; Yuan, J; Zhang, W; Zhao, H, 2020) |
| "Malignant glioma is the most common primary malignancy in the brain." | 1.56 | Sevoflurane Inhibits Glioma Cells Proliferation and Metastasis through miRNA-124-3p/ROCK1 Axis. ( Gao, C; He, XF; Meng, ZX; Shen, J, 2020) |
| "Sevoflurane is a new type of inhalation anesthetic used widely in the clinic." | 1.51 | Sevoflurane downregulates insulin-like growth factor-1 to inhibit cell proliferation, invasion and trigger apoptosis in glioma through the PI3K/AKT signaling pathway. ( Gao, C; He, XF; Shen, J; Xu, QR; Xu, YJ, 2019) |
| "Post-operative cerebral edema is a threat for patients performed gliomas resection." | 1.42 | Effects of propofol and sevoflurane on aquaporin-4 and aquaporin-9 expression in patients performed gliomas resection. ( Chang, FF; Dong, H; Lu, SJ; Qian, H; Song, CY; Yang, WC; Yue, ZY; Zhang, R; Zhou, LJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 8 (33.33) | 24.3611 |
| 2020's | 15 (62.50) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, Z | 1 |
| Gao, B | 1 |
| Zong, X | 1 |
| Gao, R | 1 |
| Kang, X | 2 |
| Li, H | 2 |
| Zhang, Z | 1 |
| Bao, X | 1 |
| Peng, Y | 4 |
| Shen, J | 3 |
| Yang, L | 3 |
| Zhu, J | 1 |
| Xie, B | 1 |
| Huang, G | 1 |
| Li, Y | 3 |
| Liu, Z | 1 |
| Wang, H | 1 |
| Cheng, G | 1 |
| Quan, L | 1 |
| Qu, H | 1 |
| Yang, A | 1 |
| Ye, J | 1 |
| Feng, Y | 1 |
| Li, X | 2 |
| Shi, X | 1 |
| Pan, H | 1 |
| Dong, J | 3 |
| Wang, D | 1 |
| Sun, H | 1 |
| Zeng, M | 3 |
| Liu, X | 2 |
| Yan, X | 1 |
| Li, R | 1 |
| Li, S | 1 |
| Han, XC | 1 |
| Zhang, YJ | 1 |
| Dong, X | 1 |
| Xing, QZ | 1 |
| Li, KH | 1 |
| Zhang, L | 4 |
| Xing, Y | 1 |
| Lin, N | 1 |
| Han, R | 3 |
| Bebawy, JF | 1 |
| Li, J | 1 |
| Zhang, M | 1 |
| Nie, L | 1 |
| Xu, W | 1 |
| Xue, R | 1 |
| Xia, R | 1 |
| Liu, WW | 1 |
| Zheng, JW | 1 |
| Tang, L | 1 |
| Kang, LY | 1 |
| Wang, W | 1 |
| Wei, WT | 1 |
| Zhao, H | 1 |
| Xing, F | 1 |
| Yuan, J | 1 |
| Li, Z | 1 |
| Zhang, W | 1 |
| Qu, Y | 1 |
| Shi, C | 1 |
| Qian, M | 1 |
| Yang, N | 1 |
| Wang, L | 1 |
| Gao, X | 1 |
| Ni, C | 1 |
| Zhan, X | 1 |
| Lei, C | 1 |
| Cheng, S | 1 |
| Cheng, J | 1 |
| Ji, N | 1 |
| Hao, S | 1 |
| Zhou, Y | 1 |
| Gao, Z | 1 |
| Gu, H | 1 |
| Ma, D | 1 |
| Gao, C | 2 |
| Meng, ZX | 1 |
| He, XF | 2 |
| Xu, QR | 1 |
| Xu, YJ | 1 |
| Wang, J | 1 |
| Fu, Z | 1 |
| Ai, Y | 1 |
| Wang, Y | 2 |
| Zhang, J | 1 |
| Dong, Y | 1 |
| Zhang, Y | 2 |
| Xie, Z | 1 |
| Shi, QY | 1 |
| Zhang, SJ | 1 |
| Liu, L | 1 |
| Chen, QS | 1 |
| Yu, LN | 1 |
| Zhang, FJ | 1 |
| Yan, M | 1 |
| Tian, Y | 1 |
| Guo, S | 1 |
| Guo, Y | 2 |
| Jian, L | 1 |
| Yang, WC | 1 |
| Zhou, LJ | 1 |
| Zhang, R | 1 |
| Yue, ZY | 1 |
| Dong, H | 1 |
| Song, CY | 1 |
| Qian, H | 1 |
| Lu, SJ | 1 |
| Chang, FF | 1 |
| Yi, W | 1 |
| Li, D | 1 |
| Huang, B | 1 |
| Yang, C | 1 |
| An, L | 1 |
| Wang, B | 1 |
| O'Leary, G | 1 |
| Bacon, CL | 1 |
| Odumeru, O | 1 |
| Fagan, C | 1 |
| Fitzpatrick, T | 1 |
| Gallagher, HC | 1 |
| Moriarty, DC | 1 |
| Regan, CM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Impact of Anesthesia on the Outcome of Supratentorial High- Grade Glioma Patients After Craniotomy[NCT02756312] | 196 participants (Anticipated) | Interventional | 2020-10-01 | Not yet recruiting | |||
| Anesthesia and Immunological and Oxidative Stress in Relation to Abdominal Cancer Surgery[NCT03974984] | 0 participants (Actual) | Observational | 2020-06-04 | Withdrawn (stopped due to Not feasable due to logistics) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for sevoflurane and Glioma
21 other studies available for sevoflurane and Glioma
| Article | Year |
|---|---|
Sevoflurane impedes glioma progression via regulating circ_0000215/miR-1200/NCR3LG1 axis.
Topics: Animals; B7 Antigens; Brain Neoplasms; Cell Movement; Glioma; Humans; Mice; Mice, Nude; MicroRNAs; R | 2021 |
Sevoflurane blocks glioma malignant development by upregulating circRELN through circRELN-mediated miR-1290/RORA axis.
Topics: Anesthetics, Inhalation; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell | 2021 |
Sevoflurane inhibits progression of glioma via regulating the HMMR antisense RNA 1/microRNA-7/cyclin dependent kinase 4 axis.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase 4; Disease Progre | 2021 |
Sevoflurane represses the progression of glioma by the regulation of circ_0037655/miR-130a-5p/RPN2 axis.
Topics: Brain Neoplasms; Cell Line, Tumor; Glioma; Hexosyltransferases; Humans; MicroRNAs; Proteasome Endope | 2022 |
Sevoflurane inhibits the malignant phenotypes of glioma through regulating miR-146b-5p/NFIB axis.
Topics: Animals; Brain Neoplasms; Cell Proliferation; Glioma; Humans; Mice; MicroRNAs; NFI Transcription Fac | 2022 |
Sevoflurane modulates the cancer stem cell-like properties and mitochondrial membrane potential of glioma via Ca
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Cell Prolife | 2020 |
Sevoflurane impedes the progression of glioma through modulating the circular RNA has_circ_0012129/miR-761/TGIF2 axis.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Movement; Cell Proliferation; Cell Survival; D | 2020 |
Sevoflurane inhibits migration and invasion of glioma cells via regulating miR-34a-5p/MMP-2 axis.
Topics: Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Gene Expression Regulation, Neoplas | 2020 |
lncRNAs Are Involved in Sevoflurane Anesthesia-Related Brain Function Modulation through Affecting Mitochondrial Function and Aging Process.
Topics: Aging; Anesthesia; Anesthetics; Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Cognition Disorde | 2020 |
Sevoflurane inhibits cell proliferation and migration of glioma by targeting the miR‑27b/VEGF axis.
Topics: Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Glioma; Human | 2021 |
Sevoflurane suppresses glioma tumorigenesis via regulating circ_0079593/miR-633/ROCK1 axis.
Topics: Animals; Apoptosis; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Prolifera | 2021 |
Impact of Anesthesia on Long-term Outcomes in Patients With Supratentorial High-grade Glioma Undergoing Tumor Resection: A Retrospective Cohort Study.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Cohort Studies; Female; Glioma; Humans; Male; Mid | 2020 |
Sevoflurane Inhibits Glioma Cells Proliferation and Metastasis through miRNA-124-3p/ROCK1 Axis.
Topics: Anesthetics, Inhalation; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Glioma; Hum | 2020 |
Sevoflurane downregulates insulin-like growth factor-1 to inhibit cell proliferation, invasion and trigger apoptosis in glioma through the PI3K/AKT signaling pathway.
Topics: Apoptosis; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplas | 2019 |
Sevoflurane suppresses migration and invasion of glioma cells by regulating miR-146b-5p and MMP16.
Topics: Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Gene Knockdown Techniques; Glioma; | 2019 |
Isoflurane and sevoflurane increase interleukin-6 levels through the nuclear factor-kappa B pathway in neuroglioma cells.
Topics: Anesthetics, Inhalation; Animals; Antimetabolites; Cell Nucleus; Cells, Cultured; Deoxyglucose; Glio | 2013 |
Sevoflurane promotes the expansion of glioma stem cells through activation of hypoxia-inducible factors in vitro.
Topics: Anesthetics, Inhalation; Blotting, Western; Cell Proliferation; Glioma; Humans; Hypoxia-Inducible Fa | 2015 |
Anesthetic Propofol Attenuates Apoptosis, Aβ Accumulation, and Inflammation Induced by Sevoflurane Through NF-κB Pathway in Human Neuroglioma Cells.
Topics: Amyloid beta-Peptides; Anesthetics; Apoptosis; Glioma; Humans; Inflammation; Methyl Ethers; Neurogli | 2015 |
Effects of propofol and sevoflurane on aquaporin-4 and aquaporin-9 expression in patients performed gliomas resection.
Topics: Aquaporin 4; Aquaporins; Blotting, Western; Brain; Brain Edema; Brain Neoplasms; Female; Glioma; Hom | 2015 |
Sevoflurane inhibits the migration and invasion of glioma cells by upregulating microRNA-637.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Ex | 2016 |
Antiproliferative actions of inhalational anesthetics: comparisons to the valproate teratogen.
Topics: Anesthetics, Inhalation; Animals; Blotting, Western; Cell Division; Dimethyl Sulfoxide; Enflurane; F | 2000 |