sevoflurane has been researched along with Disease Models, Animal in 188 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we compared sevoflurane and isoflurane with particular reference to their hemodynamic effects and ability to modify the effects of acute severe myocardial ischemia and reperfusion on ventricular arrhythmias and mortality in a porcine model of myocardial infarction." | 9.15 | Ventricular arrhythmias and mortality associated with isoflurane and sevoflurane in a porcine model of myocardial infarction. ( Ajenjo-Silverio, JM; Altónaga, JR; Cuellas-Ramón, C; de Prado, AP; Fernández-Vázquez, F; Gonzalo-Orden, JM; Orden, A; Regueiro-Purriños, M, 2011) |
| " Here we aim to explore the immunomodulatory roles of two common anesthetics, propofol and sevoflurane in breast cancer progression." | 8.31 | Immunomodulatory roles of propofol and sevoflurane in murine models of breast cancer. ( Ma, X; Song, T; Tian, J; Wang, W; Yan, R, 2023) |
| "Sevoflurane (Sev) is a commonly used volatile anesthetic that might suppress the process of breast cancer." | 8.31 | Sevoflurane suppresses the malignant progression of breast cancer via the hsa_circ_0000129/miR-578/EPSTI1 axis. ( Chen, T; Lin, Q; Lin, W; Wang, L; Zeng, X; Zheng, Q, 2023) |
| "Sevoflurane postconditioning could attenuate brain injury induced by hemorrhagic shock and resuscitation, and this neuroprotective effect may be partly by upregulation of eNOS through the phosphoinositide-3-kinase/Akt signaling pathway." | 8.12 | Phosphoinositide-3-Kinase/Akt-Endothelial Nitric Oxide Synthase Signaling Pathway Mediates the Neuroprotective Effect of Sevoflurane Postconditioning in a Rat Model of Hemorrhagic Shock and Resuscitation. ( Hu, X; Huang, C; Huang, L; Zhang, L; Zhang, M, 2022) |
| "Sevoflurane (SEV) has been reported to be an effective neuroprotective agent for cerebral ischemia/reperfusion injury (CIRI)." | 8.02 | Sevoflurane protects against cerebral ischemia/reperfusion injury via microrna-30c-5p modulating homeodomain-interacting protein kinase 1. ( Deng, M; Li, G; Qu, Y; Su, G, 2021) |
| " The inhalative anesthetic sevoflurane has been shown to elicit protective effects in various inflammatory studies, but its role in peritonitis-induced sepsis remains elusive." | 8.02 | Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling. ( Fabian, F; Fecher, D; Fuhr, A; Gamper-Tsigaras, J; Konrad, FM; Ngamsri, KC; Reutershan, J; Steinke, M; Straub, A; Walles, H, 2021) |
| "To investigate the effect of sevoflurane preconditioning on ischemia/reperfusion (I/R)-induced pulmonary/hepatic injury." | 7.91 | Effect of sevoflurane pretreatment in relieving liver ischemia/reperfusion-induced pulmonary and hepatic injury. ( Ma, X; Qu, L; Wang, X; Xiong, Y; Xu, G, 2019) |
| "The aim of this study was to explore the influences of sevoflurane inhalation therapy on circulation function and pulmonary fibrosis in rats with pulmonary arterial hypertension (PAH) and the nuclear factor-κB (NF-κB) signaling pathway." | 7.91 | Sevoflurane improves circulatory function and pulmonary fibrosis in rats with pulmonary arterial hypertension through inhibiting NF-κB signaling pathway. ( Bai, X; Li, JL; Li, SM; Xi, J; Zhao, X, 2019) |
| "The reduction in hypothermia and ischaemia-induced reperfusion arrhythmias by the addition of sevoflurane to HTK solution may be related to the phosphorylation of Cx43 at serine 368." | 7.91 | Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368. ( Gao, H; Gao, J; Li, WC; Wang, ZJ, 2019) |
| "To investigate the effect of sevoflurane on hepatic ischemia-reperfusion injury in rats via janus kinase 2/signal transducer and activator of transcription 3 (JAK2-STAT3) pathway." | 7.91 | Effect of sevoflurane on hepatic ischemia-reperfusion injury in rats via JAK2-STAT3 pathway. ( Ma, XW; Sima, LJ, 2019) |
| " In the present study, it was examined whether treatment with PPAR‑γ agonist pioglitazone (PIO) is beneficial in counteracting SEV‑induced neuroinflammation and cognitive decline in a rat model of CIH." | 7.91 | Pioglitazone prevents sevoflurane‑induced neuroinflammation and cognitive decline in a rat model of chronic intermittent hypoxia by upregulating hippocampal PPAR‑γ. ( Dong, P; Fei, J; Li, D; Li, L; Li, N; Lin, Q; Lu, L; Yang, B; Zhang, X, 2019) |
| " Sevoflurane anesthesia has been found to lead to CD and microRNAs (miRNAs) were reported to affect cognitive function." | 7.91 | Neuroprotective effect of miR-410-3p against sevoflurane anesthesia-induced cognitive dysfunction in rats through PI3K/Akt signaling pathway via targeting C-X-C motif chemokine receptor 5. ( Feng, C; Su, R; Sun, P; Xiao, W; Zhang, D; Zhong, L, 2019) |
| "These data suggest that the PI3K/Akt/mTOR pathway contributes to sevoflurane-induced neuroinflammation and that activation of PI3K/Akt/mTOR signaling by DEX could help reduce the neuroinflammatory effects of sevoflurane." | 7.91 | Dexmedetomidine suppresses sevoflurane anesthesia-induced neuroinflammation through activation of the PI3K/Akt/mTOR pathway. ( Wang, M; Wang, N, 2019) |
| "We aim to investigate the effects of sevoflurane on the ATPase activity of the hippocampal neurons in rats with cerebral ischemia-reperfusion injury (IRI) via the cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA) signaling pathway." | 7.88 | Effect of sevoflurane on the ATPase activity of hippocampal neurons in a rat model of cerebral ischemia-reperfusion injury via the cAMP-PKA signaling pathway. ( Cheng, AB; Gao, XZ; Liu, TJ; Tan, ZB; Wang, JJ; Zhang, JC; Zhang, PP; Zhang, SB, 2018) |
| "Objective We compared the effects of sevoflurane and isoflurane on systemic inflammation, sepsis-associated encephalopathy, and memory impairment in a rat sepsis model of cecal ligation and puncture (CLP)-induced polymicrobial peritonitis." | 7.88 | Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis. ( Bagriacik, EU; Bedirli, A; Bedirli, N; Cavunt Bayraktar, A; Kavutçu, M; Ozkose, Z; Yilmaz, G, 2018) |
| "Our colleagues have demonstrated an impressive therapeutic role of sevoflurane in a murine allergic airway inflammation model, but the mechanisms underlying this effect remain undefined." | 7.88 | Sevoflurane Inhibits the Th2 Response and NLRP3 Expression in Murine Allergic Airway Inflammation. ( Cheng, C; Liu, R; Shen, Q; Wang, L; Wu, H; Zha, B; Zou, H, 2018) |
| "To investigate the effect of Toll-like receptor 2 (TLR2) on the inhibition role of sevoflurane on airway inflammation in asthmatic mice." | 7.83 | [Effect of Toll-like receptor 2 on the inhibition role of sevoflurane on airway inflammation in asthmatic mice]. ( Fang, L; He, F; Liu, RY; Shen, QY; Wu, HM; Wu, L, 2016) |
| "Both propofol and sevoflurane attenuated the extent of hepatic ischemia/reperfusion injury which is evident from the hisopathological studies and alterations in liver enzymes such as AST and LDH by inhibiting Nuclear factor kappa B (NFx03BA;B) activation and subsequent alterations in inflammatory cytokines interleukin-1(IL-1), interleukin-6(IL-6), tumor necrosis factor-alpha (TNF-α) and increased IL10 release." | 7.83 | The Effects of Two Anesthetics, Propofol and Sevoflurane, on Liver Ischemia/Reperfusion Injury. ( Qi, F; Wang, H; Wang, Z; Wu, J; Xu, Z; Yu, J, 2016) |
| "Postconditioning with sevoflurane has been shown to protect against focal cerebral ischemia and reperfusion injury." | 7.81 | Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury involving mitochondrial ATP-dependent potassium channel and mitochondrial permeability transition pore. ( Liu, XZ; Wang, JK; Wu, HF; Yang, B; Zhou, H, 2015) |
| "Repeated inhalation of sevoflurane (SVF) can benefit asthmatic patients by bronchodilation." | 7.81 | Repeated inhalation of sevoflurane inhibits airway inflammation in an OVA-induced mouse model of allergic airway inflammation. ( Ding, PS; Fang, L; He, F; Liu, RY; Shen, QY; Wu, HM, 2015) |
| "To examine whether neonatal exposure to sevoflurane induces autism-like behaviors in mice." | 7.81 | Sevoflurane exposure during the neonatal period induces long-term memory impairment but not autism-like behaviors. ( Chung, W; Heo, J; Hong, J; Kim, D; Ko, Y; Lee, S; Park, S, 2015) |
| "Our modified method for murine TNBS-induced colitis using continuous inhalation anesthesia with sevoflurane provides a better experimental colitis model following both single and repeated TNBS administrations." | 7.80 | Induction of murine TNBS colitis is strictly controlled by a modified method using continuous inhalation anesthesia with sevoflurane. ( Arai, Y; Furuta, T; Kanaoka, S; Miyajima, H; Oishi, S; Osawa, S; Sugimoto, K; Sugimoto, M; Tani, S; Terai, T; Yamada, T, 2014) |
| "The aim of the present study was to explore the regulatory mechanism of heme oxygenase-1 (HO-1) expression induced by sevoflurane (Sevo) in lipopolysaccharide (LPS)‑induced acute lung injury (ALI)." | 7.80 | Post-conditioning with sevoflurane induces heme oxygenase-1 expression via the PI3K/Akt pathway in lipopolysaccharide-induced acute lung injury. ( Ai, Y; Wu, J; Zhang, L; Zhao, S, 2014) |
| "The goal of this study was to confirm whether or not sevoflurane is more effective than propofol in ameliorating the inflammatory response in an animal model of acute respiratory distress syndrome." | 7.79 | Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study. ( Aguilar, G; Belda, FJ; Ferrando, C; Moreno, J; Piqueras, L; Soro, M, 2013) |
| "The aim of current study was to investigate the protective effect of sevoflurane preconditioning at different doses on hepatic ischaemia/reperfusion injury in rats." | 7.79 | Protective effect of sevoflurane on hepatic ischaemia/reperfusion injury in the rat: A dose-response study. ( Jiang, P; Liu, H; Liu, L; Zhou, SP, 2013) |
| " The hearts with persistent ventricular fibrillation (n=16) present after 15 min of reperfusion were then randomly assigned into one of the two groups: controls (n=8), reperfusion was continued for 25 min without any intervention, and sevoflurane postconditioning (n=8), rat hearts in the sevoflurane postconditioning group were exposed to sevoflurane at a concentration of 8." | 7.75 | Sevoflurane postconditioning converts persistent ventricular fibrillation into regular rhythm. ( Chen, C; Chen, G; Yan, M; Zhang, F, 2009) |
| "Sevoflurane pretreatment can protect neuron on ischemia-reperfusion injury by attenuating neuronal apoptosis in rats." | 7.75 | [Protective effects of sevoflurane preconditioning on cerebral ischemia-reperfusion injury in rats]. ( Hu, ZY; Lin, HF; Zhu, ZR, 2009) |
| "Preconditioning with xenon and sevoflurane provided long-lasting neuroprotection in a perinatal hypoxic-ischemic model and may represent a viable method to preempt neuronal injury after an unpredictable asphyxial event in the perinatal period." | 7.74 | Xenon and sevoflurane protect against brain injury in a neonatal asphyxia model. ( Hossain, M; Ieong, E; Luo, Y; Ma, D; Maze, M; Sanders, RD; Yu, B, 2008) |
| "To investigate whether postconditioning with sevoflurane could alleviate spinal cord ischemia reperfusion injury in rabbits, and whether the beneficial effect is dependent on oxygen free radicals." | 7.74 | [Effect of sevoflurane postconditioning on spinal cord ischemia reperfusion injury via the release of oxygen free radicals in rabbits]. ( Chen, Q; Ma, R; Song, WY; Wang, Q; Xiong, LZ, 2008) |
| "There are no studies examining the effects of sevoflurane on a chronically inflamed and remodeled airway, such as that found in asthma." | 7.74 | Lung mechanics and histology during sevoflurane anesthesia in a model of chronic allergic asthma. ( Burburan, SM; Carvalho, GM; Ferreira, HC; Riva, Ddos R; Rocco, PR; Xisto, DG; Zin, WA, 2007) |
| "4% sevoflurane, cerebral ischemia caused mild neuronal damage (HE-index of 0." | 7.74 | Sevoflurane affects neurogenesis after forebrain ischemia in rats. ( Eberspächer, E; Engelhard, K; Hollweck, R; Hutzler, P; Kluge, J; Kochs, E; Werner, C; Winkelheide, U; Winkler, J, 2007) |
| "The current study was undertaken to investigate the effects of pretreatment with isoflurane and sevoflurane on the development of neurogenic pulmonary edema in an animal model." | 7.73 | Opposing effects of isoflurane and sevoflurane on neurogenic pulmonary edema development in an animal model. ( Feng, GG; Hirokawa, M; Ishikawa, K; Ishikawa, N; Kandatsu, N; Komatsu, T; Nan, YS; Nishiwaki, K; Shimada, Y; Yokochi, T, 2005) |
| "We compared the postischemic cerebral protective effects of sevoflurane and desflurane in rats with incomplete cerebral ischemia." | 7.73 | Effects of sevoflurane and desflurane in CA1 after incomplete cerebral ischemia in rats. ( Alici, HA; Cesur, M; Dogan, N; Erdem, AF; Erdogan, F; Kursad, H; Yuksek, MS, 2005) |
| "More cerebral vasodilation at hypocapnia with high doses of desflurane than with sevoflurane or isoflurane indicates that desflurane might be less suitable for neuroanaesthesia than sevoflurane and isoflurane." | 7.72 | Desflurane results in higher cerebral blood flow than sevoflurane or isoflurane at hypocapnia in pigs. ( Akeson, J; Holmström, A; Rosén, I, 2004) |
| " Sevoflurane combined with oxygen is widely applied in the clinic, and our previous study indicated that this regimen significantly reduced sepsis-induced inflammatory responses and that inhibition of NF-κB pathway activation may contribute to this protection effect." | 5.56 | A subanesthetic dose of sevoflurane combined with oxygen exerts bactericidal effects and prevents lung injury through the nitric oxide pathway during sepsis. ( Hou, L; Hu, Y; Luo, D; Luo, Z; Ma, H; Zhang, E; Zhao, X, 2020) |
| "The first step to treat aneurysmal subarachnoid hemorrhage (SAH) is aneurysmal obliteration under general anesthesia but not treat the SAH itself and the secondary effects." | 5.56 | Isoflurane versus sevoflurane for early brain injury and expression of sphingosine kinase 1 after experimental subarachnoid hemorrhage. ( Altay, BN; Altay, O; Calisir, V; Suzuki, H; Tang, J; Zhang, JH, 2020) |
| "Sevoflurane was found to elevate miR-203, and miR-203, in turn, could target and reduce DCX expression." | 5.56 | MicroRNA-203-mediated inhibition of doublecortin underpins cardioprotection conferred by sevoflurane in rats after myocardial ischaemia-reperfusion injury. ( Liu, J; Peng, H; Tan, J; Wu, Z; Yuan, W; Zhang, W, 2020) |
| "Sevoflurane has been shown to stimulate or depress memory in adult rats; however, the cellular mechanism of this bidirectional effect has not been fully investigated." | 5.48 | Different doses of sevoflurane facilitate and impair learning and memory function through activation of the ERK pathway and synthesis of ARC protein in the rat hippocampus. ( Luo, Y; Xue, QS; Yu, BW; Zhang, FJ; Zhu, QL, 2018) |
| "Sevoflurane is a widely used volatile anesthetic in the clinical setting." | 5.48 | Sevoflurane exaggerates cognitive decline in a rat model of chronic intermittent hypoxia by aggravating microglia-mediated neuroinflammation via downregulation of PPAR-γ in the hippocampus. ( Dong, P; Li, D; Li, L; Li, N; Lu, L; Yang, B; Zhang, L; Zhang, X; Zhao, J, 2018) |
| "Sevoflurane was discontinued and anesthesia continued with fentanyl/nitrous oxide for an additional 100 minutes." | 5.42 | Preischemic Administration of Sevoflurane Does not Exert Dose-dependent Effects on the Outcome of Severe Forebrain Ischemia in Rats. ( Kanazawa, K; Miura, Y; Nasu, I, 2015) |
| "Sevoflurane pretreatment were performed on WT and HIF-2α knockout mice before renal ischemia/reperfusion." | 5.42 | Sevoflurane pretreatment enhance HIF-2α expression in mice after renal ischemia/reperfusion injury. ( Chen, J; He, Z; Xu, H; Zhan, Q; Zheng, B, 2015) |
| "Morbid obesity affects the pharmacokinetics and pharmacodynamics of anesthetics, which may result in inappropriate dosing." | 5.38 | Determination of minimum alveolar concentration for isoflurane and sevoflurane in a rodent model of human metabolic syndrome. ( Britton, SL; Koch, LG; Lipinski, WJ; Lydic, R; Mashour, GA; Pal, D; Walton, ME, 2012) |
| "Sevoflurane pretreatment also suppressed the activation of astrocytes and microglias in ipsilateral cortex and corpus callosum." | 5.37 | Sevoflurane preconditioning protects blood-brain-barrier against brain ischemia. ( Chen, J; Chu, M; Gan, Y; Gao, H; Gao, Y; Li, P; Liang, W; Lu, S; Shi, H; Wang, H; Yu, Q, 2011) |
| " Here we compared sevoflurane and isoflurane with particular reference to their hemodynamic effects and ability to modify the effects of acute severe myocardial ischemia and reperfusion on ventricular arrhythmias and mortality in a porcine model of myocardial infarction." | 5.15 | Ventricular arrhythmias and mortality associated with isoflurane and sevoflurane in a porcine model of myocardial infarction. ( Ajenjo-Silverio, JM; Altónaga, JR; Cuellas-Ramón, C; de Prado, AP; Fernández-Vázquez, F; Gonzalo-Orden, JM; Orden, A; Regueiro-Purriños, M, 2011) |
| " Here we aim to explore the immunomodulatory roles of two common anesthetics, propofol and sevoflurane in breast cancer progression." | 4.31 | Immunomodulatory roles of propofol and sevoflurane in murine models of breast cancer. ( Ma, X; Song, T; Tian, J; Wang, W; Yan, R, 2023) |
| "Sevoflurane (SEV), usually causing neuronal damage and cognitive dysfunction, is one of the most commonly used anesthetics in clinical practice." | 4.31 | Knocking down Trim47 ameliorated sevoflurane-induced neuronal cell injury and cognitive impairment in rats. ( Wang, J; Wang, Q; Zhang, M; Zhu, Y, 2023) |
| "Sevoflurane (Sev) is a commonly used volatile anesthetic that might suppress the process of breast cancer." | 4.31 | Sevoflurane suppresses the malignant progression of breast cancer via the hsa_circ_0000129/miR-578/EPSTI1 axis. ( Chen, T; Lin, Q; Lin, W; Wang, L; Zeng, X; Zheng, Q, 2023) |
| "Sevoflurane postconditioning could attenuate brain injury induced by hemorrhagic shock and resuscitation, and this neuroprotective effect may be partly by upregulation of eNOS through the phosphoinositide-3-kinase/Akt signaling pathway." | 4.12 | Phosphoinositide-3-Kinase/Akt-Endothelial Nitric Oxide Synthase Signaling Pathway Mediates the Neuroprotective Effect of Sevoflurane Postconditioning in a Rat Model of Hemorrhagic Shock and Resuscitation. ( Hu, X; Huang, C; Huang, L; Zhang, L; Zhang, M, 2022) |
| "Sevoflurane (SEV) has been reported to be an effective neuroprotective agent for cerebral ischemia/reperfusion injury (CIRI)." | 4.02 | Sevoflurane protects against cerebral ischemia/reperfusion injury via microrna-30c-5p modulating homeodomain-interacting protein kinase 1. ( Deng, M; Li, G; Qu, Y; Su, G, 2021) |
| " The inhalative anesthetic sevoflurane has been shown to elicit protective effects in various inflammatory studies, but its role in peritonitis-induced sepsis remains elusive." | 4.02 | Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling. ( Fabian, F; Fecher, D; Fuhr, A; Gamper-Tsigaras, J; Konrad, FM; Ngamsri, KC; Reutershan, J; Steinke, M; Straub, A; Walles, H, 2021) |
| " Here we show that surgical dissection of primary tumors in mice under anesthesia with sevoflurane leads to significantly more lung metastasis than with propofol in both syngeneic murine 4T1 and xenograft human MDA-MB-231 breast cancer models." | 3.96 | Distinct effects of general anesthetics on lung metastasis mediated by IL-6/JAK/STAT3 pathway in mouse models. ( Huang, Y; Li, R; Lin, J, 2020) |
| "Higher brain Tau concentrations and lower brain mitochondrial metabolism in neonatal compared with adult mice contribute to developmental stage-dependent cognitive dysfunction after sevoflurane anesthesia." | 3.96 | Tau Contributes to Sevoflurane-induced Neurocognitive Impairment in Neonatal Mice. ( Boukhali, M; Dong, Y; Haas, W; Hua, F; Khatri, A; Li, M; Liu, L; Tan, H; Xie, Z; Yang, G; Yang, Y; Yu, Y; Zhang, Y, 2020) |
| "To investigate the effect of sevoflurane preconditioning on ischemia/reperfusion (I/R)-induced pulmonary/hepatic injury." | 3.91 | Effect of sevoflurane pretreatment in relieving liver ischemia/reperfusion-induced pulmonary and hepatic injury. ( Ma, X; Qu, L; Wang, X; Xiong, Y; Xu, G, 2019) |
| "The aim of this study was to explore the influences of sevoflurane inhalation therapy on circulation function and pulmonary fibrosis in rats with pulmonary arterial hypertension (PAH) and the nuclear factor-κB (NF-κB) signaling pathway." | 3.91 | Sevoflurane improves circulatory function and pulmonary fibrosis in rats with pulmonary arterial hypertension through inhibiting NF-κB signaling pathway. ( Bai, X; Li, JL; Li, SM; Xi, J; Zhao, X, 2019) |
| "The reduction in hypothermia and ischaemia-induced reperfusion arrhythmias by the addition of sevoflurane to HTK solution may be related to the phosphorylation of Cx43 at serine 368." | 3.91 | Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368. ( Gao, H; Gao, J; Li, WC; Wang, ZJ, 2019) |
| "To investigate the effect of sevoflurane on hepatic ischemia-reperfusion injury in rats via janus kinase 2/signal transducer and activator of transcription 3 (JAK2-STAT3) pathway." | 3.91 | Effect of sevoflurane on hepatic ischemia-reperfusion injury in rats via JAK2-STAT3 pathway. ( Ma, XW; Sima, LJ, 2019) |
| " In the present study, it was examined whether treatment with PPAR‑γ agonist pioglitazone (PIO) is beneficial in counteracting SEV‑induced neuroinflammation and cognitive decline in a rat model of CIH." | 3.91 | Pioglitazone prevents sevoflurane‑induced neuroinflammation and cognitive decline in a rat model of chronic intermittent hypoxia by upregulating hippocampal PPAR‑γ. ( Dong, P; Fei, J; Li, D; Li, L; Li, N; Lin, Q; Lu, L; Yang, B; Zhang, X, 2019) |
| " Sevoflurane anesthesia has been found to lead to CD and microRNAs (miRNAs) were reported to affect cognitive function." | 3.91 | Neuroprotective effect of miR-410-3p against sevoflurane anesthesia-induced cognitive dysfunction in rats through PI3K/Akt signaling pathway via targeting C-X-C motif chemokine receptor 5. ( Feng, C; Su, R; Sun, P; Xiao, W; Zhang, D; Zhong, L, 2019) |
| "These data suggest that the PI3K/Akt/mTOR pathway contributes to sevoflurane-induced neuroinflammation and that activation of PI3K/Akt/mTOR signaling by DEX could help reduce the neuroinflammatory effects of sevoflurane." | 3.91 | Dexmedetomidine suppresses sevoflurane anesthesia-induced neuroinflammation through activation of the PI3K/Akt/mTOR pathway. ( Wang, M; Wang, N, 2019) |
| "We aim to investigate the effects of sevoflurane on the ATPase activity of the hippocampal neurons in rats with cerebral ischemia-reperfusion injury (IRI) via the cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA) signaling pathway." | 3.88 | Effect of sevoflurane on the ATPase activity of hippocampal neurons in a rat model of cerebral ischemia-reperfusion injury via the cAMP-PKA signaling pathway. ( Cheng, AB; Gao, XZ; Liu, TJ; Tan, ZB; Wang, JJ; Zhang, JC; Zhang, PP; Zhang, SB, 2018) |
| "Sevoflurane can inhibit retinal angiogenesis via suppressing VEGF expression in an OIR mice model with exposure to relative hypoxia." | 3.88 | The effect of sevoflurane on retinal angiogenesis in a mouse model of oxygen-induced retinopathy. ( Bae, SS; Baek, SH; Baik, SW; Byeon, GJ; Ha, JM; Kim, HJ; Kim, HY; Kim, M; Kim, SH; Ri, HS, 2018) |
| "Objective We compared the effects of sevoflurane and isoflurane on systemic inflammation, sepsis-associated encephalopathy, and memory impairment in a rat sepsis model of cecal ligation and puncture (CLP)-induced polymicrobial peritonitis." | 3.88 | Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis. ( Bagriacik, EU; Bedirli, A; Bedirli, N; Cavunt Bayraktar, A; Kavutçu, M; Ozkose, Z; Yilmaz, G, 2018) |
| "After approval by the institutional animal care and use committee, 36 Japanese White rabbits underwent partial hepatic ischemia for 90 min either under sevoflurane or propofol anesthesia." | 3.88 | Interaction between anesthetic conditioning and ischemic preconditioning on metabolic function after hepatic ischemia-reperfusion in rabbits. ( Kosugi, S; Kotake, Y; Morisaki, H; Nagata, H; Suzuki, T; Yamada, T, 2018) |
| "Our colleagues have demonstrated an impressive therapeutic role of sevoflurane in a murine allergic airway inflammation model, but the mechanisms underlying this effect remain undefined." | 3.88 | Sevoflurane Inhibits the Th2 Response and NLRP3 Expression in Murine Allergic Airway Inflammation. ( Cheng, C; Liu, R; Shen, Q; Wang, L; Wu, H; Zha, B; Zou, H, 2018) |
| "Analgesic mouse models were established by intraperitoneal injection of emulsified sevoflurane, and the influence of p-MPPF (a specific antagonist of 5-HT1A Rs) intrathecal injection on the changes in tail-flick latency in tail-withdrawal test, pain threshold in hot-plate test (HPPT), and writhing times in acetic acid-induced writhing test were recorded." | 3.85 | 5-HT1A Receptors Mediate Analgesia Induced by Emulsified Sevoflurane in Thermal Nociception but Have Little Effect on Chemical Nociception. ( Gao, C; Hong, T; Shen, J; Ti-Jun, D; Xin, L; Yan, C; Zhi-Xiu, M, 2017) |
| "In animal models, both sevoflurane and propofol protect against acute lung injury (ALI), especially when administered prior to ALI onset." | 3.85 | Sevoflurane Posttreatment Attenuates Lung Injury Induced by Oleic Acid in Dogs. ( Du, G; Li, Z; Liu, J; Wang, S, 2017) |
| " It has demonstrated that sevoflurane has neuroprotective effects against ischemic stroke, but its effects on ischemia-induced formation of astrogliosis and glial scar are unknown." | 3.85 | Sevoflurane postconditioning attenuates reactive astrogliosis and glial scar formation after ischemia-reperfusion brain injury. ( Gao, X; Kent, TA; Li, W; Ni, Y; Qiao, SG; Wang, C; Xu, XX; Zhang, HL; Zhu, YM, 2017) |
| "The antiapoptotic effects of sevoflurane postconditioning are responsible for neuroprotection against cerebral ischemia-reperfusion injury." | 3.85 | Sevoflurane Postconditioning Reduces Apoptosis by Activating the JAK-STAT Pathway After Transient Global Cerebral Ischemia in Rats. ( Bae, JI; Hwang, JW; Jeon, YT; Kim, E; Kim, HC; Lee, KH; Lim, YJ; Min, SW; Park, HP, 2017) |
| " In vivo studies demonstrated that sevoflurane post-conditioning (SpostC) was cardioprotective against ischaemia/reperfusion injury, which was blocked by hyperglycaemia." | 3.85 | High glucose concentration abrogates sevoflurane post-conditioning cardioprotection by advancing mitochondrial fission but dynamin-related protein 1 inhibitor restores these effects. ( Ma, HP; Maimaitili, Y; Wang, J; Wu, JJ; Xie, P; Yang, YN; Yu, J; Zheng, H, 2017) |
| "To investigate the effect of Toll-like receptor 2 (TLR2) on the inhibition role of sevoflurane on airway inflammation in asthmatic mice." | 3.83 | [Effect of Toll-like receptor 2 on the inhibition role of sevoflurane on airway inflammation in asthmatic mice]. ( Fang, L; He, F; Liu, RY; Shen, QY; Wu, HM; Wu, L, 2016) |
| "Both propofol and sevoflurane attenuated the extent of hepatic ischemia/reperfusion injury which is evident from the hisopathological studies and alterations in liver enzymes such as AST and LDH by inhibiting Nuclear factor kappa B (NFx03BA;B) activation and subsequent alterations in inflammatory cytokines interleukin-1(IL-1), interleukin-6(IL-6), tumor necrosis factor-alpha (TNF-α) and increased IL10 release." | 3.83 | The Effects of Two Anesthetics, Propofol and Sevoflurane, on Liver Ischemia/Reperfusion Injury. ( Qi, F; Wang, H; Wang, Z; Wu, J; Xu, Z; Yu, J, 2016) |
| "Postconditioning with sevoflurane has been shown to protect against focal cerebral ischemia and reperfusion injury." | 3.81 | Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury involving mitochondrial ATP-dependent potassium channel and mitochondrial permeability transition pore. ( Liu, XZ; Wang, JK; Wu, HF; Yang, B; Zhou, H, 2015) |
| "Repeated inhalation of sevoflurane (SVF) can benefit asthmatic patients by bronchodilation." | 3.81 | Repeated inhalation of sevoflurane inhibits airway inflammation in an OVA-induced mouse model of allergic airway inflammation. ( Ding, PS; Fang, L; He, F; Liu, RY; Shen, QY; Wu, HM, 2015) |
| "Ischemic postconditioning (stutter CPR) and sevoflurane have been shown to mitigate the effects of reperfusion injury in cardiac tissue after 15min of ventricular fibrillation (VF) cardiac arrest." | 3.81 | Bundled postconditioning therapies improve hemodynamics and neurologic recovery after 17 min of untreated cardiac arrest. ( Bartos, JA; Bates, FS; Debaty, G; Lurie, KG; Matsuura, TR; McKnite, SH; Metzger, JM; Neumar, RW; Rees, JN; Riess, ML; Sarraf, M; Segal, N; Sloper, DT; Yannopoulos, D; Youngquist, ST, 2015) |
| "To examine whether neonatal exposure to sevoflurane induces autism-like behaviors in mice." | 3.81 | Sevoflurane exposure during the neonatal period induces long-term memory impairment but not autism-like behaviors. ( Chung, W; Heo, J; Hong, J; Kim, D; Ko, Y; Lee, S; Park, S, 2015) |
| "Our modified method for murine TNBS-induced colitis using continuous inhalation anesthesia with sevoflurane provides a better experimental colitis model following both single and repeated TNBS administrations." | 3.80 | Induction of murine TNBS colitis is strictly controlled by a modified method using continuous inhalation anesthesia with sevoflurane. ( Arai, Y; Furuta, T; Kanaoka, S; Miyajima, H; Oishi, S; Osawa, S; Sugimoto, K; Sugimoto, M; Tani, S; Terai, T; Yamada, T, 2014) |
| "The aim of the present study was to explore the regulatory mechanism of heme oxygenase-1 (HO-1) expression induced by sevoflurane (Sevo) in lipopolysaccharide (LPS)‑induced acute lung injury (ALI)." | 3.80 | Post-conditioning with sevoflurane induces heme oxygenase-1 expression via the PI3K/Akt pathway in lipopolysaccharide-induced acute lung injury. ( Ai, Y; Wu, J; Zhang, L; Zhao, S, 2014) |
| "The goal of this study was to confirm whether or not sevoflurane is more effective than propofol in ameliorating the inflammatory response in an animal model of acute respiratory distress syndrome." | 3.79 | Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study. ( Aguilar, G; Belda, FJ; Ferrando, C; Moreno, J; Piqueras, L; Soro, M, 2013) |
| "The aim of current study was to investigate the protective effect of sevoflurane preconditioning at different doses on hepatic ischaemia/reperfusion injury in rats." | 3.79 | Protective effect of sevoflurane on hepatic ischaemia/reperfusion injury in the rat: A dose-response study. ( Jiang, P; Liu, H; Liu, L; Zhou, SP, 2013) |
| "Mice (N = 12 per treatment group) were exposed to anesthetic concentrations of desflurane, isoflurane, and sevoflurane either during induction of sepsis or when the mice showed pronounced symptoms of inflammation." | 3.79 | Volatile anesthetics improve survival after cecal ligation and puncture. ( Beck-Schimmer, B; Castellon, M; Hasler, M; Herrmann, IK; Hu, G; Minshall, RD; Schwartz, DE; Urner, M, 2013) |
| "Under both normovolemia and hypovolemia, glucose levels in rats anesthetized with sevoflurane were significantly higher than those in rats anesthetized with propofol, and insulin levels in rats anesthetized with sevoflurane were significantly lower than those in rats anesthetized with propofol." | 3.78 | The involvement of adenosine triphosphate-sensitive potassium channels in the different effects of sevoflurane and propofol on glucose metabolism in fed rats. ( Kawamura, G; Kitamura, T; Sato, K; Yamada, Y, 2012) |
| "This study aimed to evaluate the differential protective effects of isoflurane or sevoflurane on lung inflammation in a rat model of cecal ligation and puncture (CLP) induced sepsis." | 3.78 | Volatile anesthetic preconditioning attenuated sepsis induced lung inflammation. ( Akkaya, T; Alper, M; Bedirli, A; Bedirli, N; Demirtas, CY; Pasaoglu, H; Salman, B, 2012) |
| " We hypothesized that the volatile anesthetic sevoflurane (SEVO) attenuates lung inflammation through activation of lung epithelial GABA(A) receptors." | 3.78 | Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury. ( Fortis, S; Haitsma, JJ; Lu, WY; Mazer, CD; Parotto, M; Slutsky, AS; Spieth, PM; Zhang, H; Zhong, N, 2012) |
| "Sevoflurane preconditioning protects mitochondria from cerebral ischemia/reperfusion injury and ameliorates long-term neurological deficits." | 3.78 | Sevoflurane preconditioning improves mitochondrial function and long-term neurologic sequelae after transient cerebral ischemia: role of mitochondrial permeability transition. ( Han, J; Kong, X; Li, N; Liu, X; Xiong, L; Yang, Q; Ye, R; Zhang, Y; Zhao, G, 2012) |
| "0 MAC halothane, isoflurane, and sevoflurane on phrenic nerve activity in euoxia (baseline) and during acute normocapnic hypoxia (inspired oxygen fraction 0." | 3.76 | The acute hypoxic ventilatory response under halothane, isoflurane, and sevoflurane anaesthesia in rats. ( Carev, M; Dogas, Z; Jeroncic, A; Karanovic, N; Karanovic, S; Pecotic, R; Ujevic, A; Valic, M, 2010) |
| "We conclude that no difference could be detected between choosing equipotent doses of halothane, sevoflurane, or isoflurane in relation to renal variables in dogs submitted to pressure-adjusted hemorrhagic shock and resuscitation." | 3.75 | Does the choice of the halogenated anesthetic influence renal function during hemorrhagic shock and resuscitation? ( Braz, JR; Braz, LG; Castiglia, YM; Módolo, NS; Roberto, WM; Silva, AE; Vane, LA; Vianna, PT, 2009) |
| " The hearts with persistent ventricular fibrillation (n=16) present after 15 min of reperfusion were then randomly assigned into one of the two groups: controls (n=8), reperfusion was continued for 25 min without any intervention, and sevoflurane postconditioning (n=8), rat hearts in the sevoflurane postconditioning group were exposed to sevoflurane at a concentration of 8." | 3.75 | Sevoflurane postconditioning converts persistent ventricular fibrillation into regular rhythm. ( Chen, C; Chen, G; Yan, M; Zhang, F, 2009) |
| "These results suggest that inhalational anesthetic sevoflurane may promote Alzheimer disease neuropathogenesis." | 3.75 | The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels. ( Crosby, G; Culley, DJ; Dong, Y; Marcantonio, ER; Moir, RD; Tanzi, RE; Xia, W; Xie, Z; Zhang, B; Zhang, G, 2009) |
| "Sevoflurane pretreatment can protect neuron on ischemia-reperfusion injury by attenuating neuronal apoptosis in rats." | 3.75 | [Protective effects of sevoflurane preconditioning on cerebral ischemia-reperfusion injury in rats]. ( Hu, ZY; Lin, HF; Zhu, ZR, 2009) |
| "Preconditioning with xenon and sevoflurane provided long-lasting neuroprotection in a perinatal hypoxic-ischemic model and may represent a viable method to preempt neuronal injury after an unpredictable asphyxial event in the perinatal period." | 3.74 | Xenon and sevoflurane protect against brain injury in a neonatal asphyxia model. ( Hossain, M; Ieong, E; Luo, Y; Ma, D; Maze, M; Sanders, RD; Yu, B, 2008) |
| "To investigate whether postconditioning with sevoflurane could alleviate spinal cord ischemia reperfusion injury in rabbits, and whether the beneficial effect is dependent on oxygen free radicals." | 3.74 | [Effect of sevoflurane postconditioning on spinal cord ischemia reperfusion injury via the release of oxygen free radicals in rabbits]. ( Chen, Q; Ma, R; Song, WY; Wang, Q; Xiong, LZ, 2008) |
| "There are no studies examining the effects of sevoflurane on a chronically inflamed and remodeled airway, such as that found in asthma." | 3.74 | Lung mechanics and histology during sevoflurane anesthesia in a model of chronic allergic asthma. ( Burburan, SM; Carvalho, GM; Ferreira, HC; Riva, Ddos R; Rocco, PR; Xisto, DG; Zin, WA, 2007) |
| "4% sevoflurane, cerebral ischemia caused mild neuronal damage (HE-index of 0." | 3.74 | Sevoflurane affects neurogenesis after forebrain ischemia in rats. ( Eberspächer, E; Engelhard, K; Hollweck, R; Hutzler, P; Kluge, J; Kochs, E; Werner, C; Winkelheide, U; Winkler, J, 2007) |
| "Pre-ischaemic sevoflurane was found to reduce the extent of myocardial necrosis, but the change was not significant, whereas IP reduced IS by 50% (P= 0." | 3.74 | Pre-occlusion ischaemia, not sevoflurane, successfully preconditions the myocardium against further damage in porcine in vivo hearts. ( Aagaard, SR; Hasenkam, JM; Larsen, JR; Sloth, E, 2007) |
| " After having established the mouse model of analgesia by intraperitoneal or subcutaneous injections of appropriate doses of emulsified enflurane, isoflurane or sevoflurane, we injected different doses of AMPA intrathecally and observed effects on the pain threshold using the hot-plate and acetic acid-induced writhing tests." | 3.74 | Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics. ( Dai, TJ; Hang, LH; Shao, DH; Yang, YH; Zeng, YM, 2007) |
| "We conclude that the severity of remote lung injury was not different between sevoflurane and propofol anaesthesia in this porcine model of severe lower-body ischaemia and reperfusion injury." | 3.74 | Lung injury following thoracic aortic occlusion: comparison of sevoflurane and propofol anaesthesia. ( Annecke, T; Bittmann, I; Conzen, PF; Hilberath, JM; Kahr, S; Kemming, GI; Krombach, F; Kubitz, JC; Langer, K; Rehm, M, 2008) |
| "In the present study, we tested the ability of sevoflurane to induce early and late preconditioning against ischemic neuronal injury using an in vivo model of global cerebral ischemia in the rat." | 3.73 | Sevoflurane-induced preconditioning protects against cerebral ischemic neuronal damage in rats. ( Akca, O; Kehl, F; Payne, RS; Roewer, N; Schurr, A, 2005) |
| "The current study was undertaken to investigate the effects of pretreatment with isoflurane and sevoflurane on the development of neurogenic pulmonary edema in an animal model." | 3.73 | Opposing effects of isoflurane and sevoflurane on neurogenic pulmonary edema development in an animal model. ( Feng, GG; Hirokawa, M; Ishikawa, K; Ishikawa, N; Kandatsu, N; Komatsu, T; Nan, YS; Nishiwaki, K; Shimada, Y; Yokochi, T, 2005) |
| "We compared the postischemic cerebral protective effects of sevoflurane and desflurane in rats with incomplete cerebral ischemia." | 3.73 | Effects of sevoflurane and desflurane in CA1 after incomplete cerebral ischemia in rats. ( Alici, HA; Cesur, M; Dogan, N; Erdem, AF; Erdogan, F; Kursad, H; Yuksek, MS, 2005) |
| "More cerebral vasodilation at hypocapnia with high doses of desflurane than with sevoflurane or isoflurane indicates that desflurane might be less suitable for neuroanaesthesia than sevoflurane and isoflurane." | 3.72 | Desflurane results in higher cerebral blood flow than sevoflurane or isoflurane at hypocapnia in pigs. ( Akeson, J; Holmström, A; Rosén, I, 2004) |
| "Sevoflurane was not associated with increases in heart rate in adult patients and volunteers, whereas higher MACs of isoflurane and desflurane and rapid increases in the inspired concentrations of these two anesthetics have been associated with tachycardia." | 2.39 | Cardiovascular responses to sevoflurane: a review. ( Ebert, TJ; Harkin, CP; Muzi, M, 1995) |
| "Sevoflurane is a general anesthetic agent which is commonly used in clinical practice." | 1.72 | Sevoflurane Induces Neurotoxicity in the Animal Model with Alzheimer's Disease Neuropathology via Modulating Glutamate Transporter and Neuronal Apoptosis. ( Chang, RCC; Chu, JMT; Huang, C; Kwong, VSW; Liu, Y; Wong, GTC, 2022) |
| " This study revealed a new toxic mechanism of Sev to the brain occurred through the dysfunction of iron metabolism." | 1.62 | Effect of sevoflurane on iron homeostasis and toxicity in the brain of mice. ( Chang, Y; Gao, G; Li, X; Li, Y; Shi, Z; Thirupathi, A; Wang, M; Yu, P; Zhou, C; Zuo, Y, 2021) |
| "Sevoflurane post-treatment decreased G9a and H3K9me2 levels, and G9a level was negatively correlated with NRF2 level." | 1.62 | Post-Treatment Sevoflurane Protects Against Hypoxic-Ischemic Brain Injury in Neonatal Rats by Downregulating Histone Methyltransferase G9a and Upregulating Nuclear Factor Erythroid 2-Related Factor 2 (NRF2). ( Li, X; Wang, H; Xu, Y; Zhang, H; Zhu, S, 2021) |
| " Sevoflurane combined with oxygen is widely applied in the clinic, and our previous study indicated that this regimen significantly reduced sepsis-induced inflammatory responses and that inhibition of NF-κB pathway activation may contribute to this protection effect." | 1.56 | A subanesthetic dose of sevoflurane combined with oxygen exerts bactericidal effects and prevents lung injury through the nitric oxide pathway during sepsis. ( Hou, L; Hu, Y; Luo, D; Luo, Z; Ma, H; Zhang, E; Zhao, X, 2020) |
| "The first step to treat aneurysmal subarachnoid hemorrhage (SAH) is aneurysmal obliteration under general anesthesia but not treat the SAH itself and the secondary effects." | 1.56 | Isoflurane versus sevoflurane for early brain injury and expression of sphingosine kinase 1 after experimental subarachnoid hemorrhage. ( Altay, BN; Altay, O; Calisir, V; Suzuki, H; Tang, J; Zhang, JH, 2020) |
| "Sevoflurane was found to elevate miR-203, and miR-203, in turn, could target and reduce DCX expression." | 1.56 | MicroRNA-203-mediated inhibition of doublecortin underpins cardioprotection conferred by sevoflurane in rats after myocardial ischaemia-reperfusion injury. ( Liu, J; Peng, H; Tan, J; Wu, Z; Yuan, W; Zhang, W, 2020) |
| "Myocardial dysfunction accompanied by severe sepsis could significantly increase the mortality rate of septic patients." | 1.51 | Sevoflurane Preconditioning Prevents Septic Myocardial Dysfunction in Lipopolysaccharide-Challenged Mice. ( Chen, Y; Li, H; Li, J; Li, Y; Liu, P; Qi, R; Wang, Y, 2019) |
| "Sevoflurane after-treatment revived the intensity of fluorescence of the endothelial glycocalyx compared to the hydrogen peroxide group." | 1.51 | Sevoflurane Promotes Regeneration of the Endothelial Glycocalyx by Upregulating Sialyltransferase. ( Azumaguchi, R; Hamada, K; Kazuma, S; Kimizuka, M; Tokinaga, Y; Yamakage, M, 2019) |
| "The treatment of sevoflurane could reduce miR-155 expression and increased SIRT1 expression in the myocardial tissues, under which conditions, cardiac functions were promoted, accompanied by reduced infarct size and inhibited cardiomyocyte apoptosis." | 1.51 | Downregulation of microRNA-155 stimulates sevoflurane-mediated cardioprotection against myocardial ischemia/reperfusion injury by binding to SIRT1 in mice. ( Hao, F; Hu, X; Huang, G, 2019) |
| "Sevoflurane is a common anesthetic widely used in clinical practice." | 1.51 | Transcriptomic analysis reveals the molecular mechanism of Alzheimer-related neuropathology induced by sevoflurane in mice. ( Chang, YZ; Gao, G; Ge, X; Israr, M; Li, B; Shi, Z; Yu, P; Zhang, Y; Zuo, Y, 2019) |
| "Sevoflurane has been shown to stimulate or depress memory in adult rats; however, the cellular mechanism of this bidirectional effect has not been fully investigated." | 1.48 | Different doses of sevoflurane facilitate and impair learning and memory function through activation of the ERK pathway and synthesis of ARC protein in the rat hippocampus. ( Luo, Y; Xue, QS; Yu, BW; Zhang, FJ; Zhu, QL, 2018) |
| "Sevoflurane is a widely used volatile anesthetic in the clinical setting." | 1.48 | Sevoflurane exaggerates cognitive decline in a rat model of chronic intermittent hypoxia by aggravating microglia-mediated neuroinflammation via downregulation of PPAR-γ in the hippocampus. ( Dong, P; Li, D; Li, L; Li, N; Lu, L; Yang, B; Zhang, L; Zhang, X; Zhao, J, 2018) |
| "Sevoflurane is a volatile anesthetic gradually used in recent years." | 1.46 | Safety Evaluation of Sevoflurane as Anesthetic Agent in Mouse Model of Myocardial Ischemic Infarction. ( Cheng, X; Han, P; Hou, J; Kang, YJ; Liu, J; Sheng, Q; Sun, X, 2017) |
| "Diet-induced prediabetes is associated with impaired myocardial perfusion and function in rats." | 1.43 | Myocardial Perfusion and Function Are Distinctly Altered by Sevoflurane Anesthesia in Diet-Induced Prediabetic Rats. ( Boer, C; Boly, CA; Bouwman, RA; Bulte, CS; Kwekkeboom, RF; Loer, SA; van den Akker, RF; van den Brom, CE, 2016) |
| "Desflurane failed to inhibit inflammatory responses and ROS production in lung tissue and developed no antioxidant potential." | 1.43 | Inhaled Anesthetics Exert Different Protective Properties in a Mouse Model of Ventilator-Induced Lung Injury. ( Buerkle, H; Engelstaedter, H; Faller, S; Gyllenram, V; Hoetzel, A; Spassov, S; Strosing, KM, 2016) |
| "Our asphyxia cardiac arrest (ACA) rat model is well established." | 1.43 | Anesthesia specific differences in a cardio-pulmonary resuscitation rat model; halothane versus sevoflurane. ( Ebmeyer, U; Esser, T; Keilhoff, G, 2016) |
| "Sevoflurane was discontinued and anesthesia continued with fentanyl/nitrous oxide for an additional 100 minutes." | 1.42 | Preischemic Administration of Sevoflurane Does not Exert Dose-dependent Effects on the Outcome of Severe Forebrain Ischemia in Rats. ( Kanazawa, K; Miura, Y; Nasu, I, 2015) |
| "Patients with Parkinson's disease (PD) often require surgery, and therefore may receive inhalation anesthesia." | 1.42 | Effects of sevoflurane on leucine-rich repeat kinase 2-associated Drosophila model of Parkinson's disease. ( Cai, S; Gu, H; Kuang, L; Shan, Z; Wang, Q; Wen, J; Xiu, H; Xu, K; Zhang, T, 2015) |
| "Post-traumatic stress disorder (PTSD) is a psychiatric disease that may occur after intense psychological trauma or physiological stress." | 1.42 | Sevoflurane attenuates stress-enhanced fear learning by regulating hippocampal BDNF expression and Akt/GSK-3β signaling pathway in a rat model of post-traumatic stress disorder. ( Chen, C; Ji, M; Li, W; Liu, J; Sun, Q; Xu, Q; Zhang, Y; Zhu, S, 2015) |
| "Sevoflurane pretreatment were performed on WT and HIF-2α knockout mice before renal ischemia/reperfusion." | 1.42 | Sevoflurane pretreatment enhance HIF-2α expression in mice after renal ischemia/reperfusion injury. ( Chen, J; He, Z; Xu, H; Zhan, Q; Zheng, B, 2015) |
| "Increasingly more aged people with Alzheimer's disease (AD) must undergo surgery with general anesthesia for various reasons." | 1.40 | Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice. ( Deng, Y; He, Z; Lu, B; Qi, B; Su, D; Tian, J; Wang, X; Xu, H; Zheng, B, 2014) |
| "Isoflurane exposure was associated with weaker seizure-like electroencephalogram patterns than sevoflurane exposure." | 1.39 | Developmental effects of neonatal isoflurane and sevoflurane exposure in rats. ( Gravenstein, N; Martynyuk, AE; Pavlinec, C; Seubert, CN; Zhu, W, 2013) |
| "Sevoflurane treatment also caused increased phosphorylation of p38 MAPK at 24 and 72 h after reperfusion." | 1.38 | Delayed neuroprotection induced by sevoflurane via opening mitochondrial ATP-sensitive potassium channels and p38 MAPK phosphorylation. ( Guo, Q; Wang, E; Wang, N; Xia, P; Ye, Z; Yuan, Y, 2012) |
| "Successful resuscitation after cardiac arrest is typically associated with cerebral and myocardial ischemia/reperfusion (I/R)-injury." | 1.38 | Hypothermia and anesthetic postconditioning influence the expression and activity of small intestinal proteins possibly involved in ischemia/reperfusion-mediated events following cardiopulmonary resuscitation. ( Albrecht, M; Bein, B; Gruenewald, M; Meybohm, P; Scholz, J; Zacharowski, K; Zitta, K, 2012) |
| "Morbid obesity affects the pharmacokinetics and pharmacodynamics of anesthetics, which may result in inappropriate dosing." | 1.38 | Determination of minimum alveolar concentration for isoflurane and sevoflurane in a rodent model of human metabolic syndrome. ( Britton, SL; Koch, LG; Lipinski, WJ; Lydic, R; Mashour, GA; Pal, D; Walton, ME, 2012) |
| "Total sleep deprivation resulted in significantly increased NREM and REM sleep for 12-h postdeprivation." | 1.37 | State-specific effects of sevoflurane anesthesia on sleep homeostasis: selective recovery of slow wave but not rapid eye movement sleep. ( Lipinski, WJ; Mashour, GA; Pal, D; Turner, AM; Walker, AJ, 2011) |
| "Sevoflurane/olprinone treatment attenuated the bronchoconstriction induced by the highest dose of Ach with RL being significantly lower (0." | 1.37 | Synergic bronchodilator effects of a phosphodiesterase 3 inhibitor olprinone with a volatile anaesthetic sevoflurane in ovalbumin-sensitised guinea pigs. ( Iwasaki, S; Watanabe, A; Yamakage, M; Zhou, J, 2011) |
| "Sevoflurane pretreatment also suppressed the activation of astrocytes and microglias in ipsilateral cortex and corpus callosum." | 1.37 | Sevoflurane preconditioning protects blood-brain-barrier against brain ischemia. ( Chen, J; Chu, M; Gan, Y; Gao, H; Gao, Y; Li, P; Liang, W; Lu, S; Shi, H; Wang, H; Yu, Q, 2011) |
| "Twenty-two pigs were subjected to cardiac arrest." | 1.37 | Pharmacological postconditioning with sevoflurane after cardiopulmonary resuscitation reduces myocardial dysfunction. ( Albrecht, M; Bein, B; Foesel, N; Gruenewald, M; Maracke, M; Meybohm, P; Müller, C; Scholz, J; Schrezenmeir, J; Tacke, S; Zitta, K, 2011) |
| "As the muscle atrophy model, Sprague-Dawley rats were subjected to hindlimb immobilization for 2 wk." | 1.36 | The effect of amino acid infusion on anesthesia-induced hypothermia in muscle atrophy model rats. ( Ando, S; Kanazawa, M; Suzuki, T; Tsuda, M, 2010) |
| "Using a mouse model of postoperative pain, we assessed the expression of MOR and delta opioid receptors (DORs) and the efficacy of Herpes Simplex vector-mediated proenkephalin release (SHPE) preventing postoperative nociceptive sensitization induced by remifentanil or surgical incision." | 1.35 | The pro-nociceptive effects of remifentanil or surgical injury in mice are associated with a decrease in delta-opioid receptor mRNA levels: Prevention of the nociceptive response by on-site delivery of enkephalins. ( Cabañero, D; Célérier, E; García-Nogales, P; Maldonado, R; Mata, M; Puig, MM; Roques, BP, 2009) |
| "Sevoflurane effects on opioid-induced hyperalgesia have not been yet evaluated in vivo." | 1.35 | Effects of sevoflurane on carrageenan- and fentanyl-induced pain hypersensitivity in Sprague-Dawley rats. ( Janvier, G; Laulin, JP; Maurette, P; Richebé, P; Rivalan, B; Rivat, C; Simonnet, G, 2009) |
| "Concomitant left ventricular hypertrophy is found in some cardiac surgery patients and could change cardioprotection efficacy." | 1.35 | Hypertrophied hearts: what of sevoflurane cardioprotection? ( Christensen, SD; Hasenkam, JM; Larsen, JR; Sivesgaard, K; Sloth, E; Smerup, M; Torp, P, 2009) |
| "Sevoflurane was applied after the onset of injury, simulating a "postconditioning" scenario." | 1.35 | Postconditioning with a volatile anaesthetic in alveolar epithelial cells in vitro. ( Beck-Schimmer, B; Blumenthal, S; Booy, C; Neff, SB; Neff, TA; Reyes, L; Roth Z'graggen, B; Schmid, ER; Spahn, DR; Steurer, M; Yue, T, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (1.06) | 18.2507 |
| 2000's | 30 (15.96) | 29.6817 |
| 2010's | 115 (61.17) | 24.3611 |
| 2020's | 41 (21.81) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, S | 1 |
| Liu, Y | 3 |
| Huang, S | 1 |
| Jin, F | 1 |
| Qi, F | 2 |
| Liu, Z | 1 |
| Yang, B | 6 |
| Shen, M | 1 |
| Lian, N | 1 |
| Song, C | 1 |
| Qin, C | 1 |
| Yu, Y | 8 |
| He, B | 1 |
| Wang, J | 6 |
| Zhang, M | 3 |
| Huang, C | 3 |
| Zhang, L | 9 |
| Huang, L | 2 |
| Hu, X | 4 |
| Gao, Y | 3 |
| Zhao, T | 1 |
| Chen, Y | 2 |
| Sun, Z | 2 |
| Lu, J | 1 |
| Shi, Z | 3 |
| Song, X | 1 |
| Yang, Y | 5 |
| Liang, F | 2 |
| Gao, J | 2 |
| Dong, Y | 6 |
| Zhang, Y | 14 |
| Yang, G | 3 |
| Soriano, SG | 3 |
| Feng, HJ | 1 |
| Xie, Z | 7 |
| Han, F | 1 |
| Zhao, J | 4 |
| Zhao, G | 2 |
| Su, G | 1 |
| Qu, Y | 1 |
| Li, G | 1 |
| Deng, M | 1 |
| Niikura, R | 1 |
| Miyazaki, T | 1 |
| Takase, K | 1 |
| Sasaguri, H | 1 |
| Saito, T | 1 |
| Saido, TC | 1 |
| Goto, T | 1 |
| Chu, JMT | 1 |
| Kwong, VSW | 1 |
| Chang, RCC | 2 |
| Wong, GTC | 2 |
| Yan, R | 1 |
| Song, T | 2 |
| Wang, W | 2 |
| Tian, J | 2 |
| Ma, X | 2 |
| Zhu, Y | 1 |
| Wang, Q | 4 |
| Zeng, X | 1 |
| Zheng, Q | 1 |
| Wang, L | 3 |
| Chen, T | 1 |
| Lin, W | 1 |
| Lin, Q | 2 |
| Li, J | 3 |
| Liu, P | 1 |
| Li, H | 4 |
| Wang, Y | 1 |
| Qi, R | 1 |
| Li, Y | 5 |
| Xu, G | 3 |
| Wang, X | 3 |
| Xiong, Y | 1 |
| Qu, L | 1 |
| Liu, C | 1 |
| Ding, R | 1 |
| Huang, W | 1 |
| Miao, L | 1 |
| Shi, CX | 1 |
| Jin, J | 1 |
| Wang, XQ | 1 |
| Li, GH | 1 |
| Li, KZ | 1 |
| Ma, JH | 1 |
| Zhao, X | 2 |
| Bai, X | 2 |
| Li, JL | 1 |
| Li, SM | 1 |
| Xi, J | 1 |
| Li, R | 1 |
| Huang, Y | 1 |
| Lin, J | 1 |
| Zhang, E | 1 |
| Ma, H | 3 |
| Luo, D | 1 |
| Hu, Y | 1 |
| Hou, L | 1 |
| Luo, Z | 2 |
| Yu, F | 1 |
| Tong, LJ | 1 |
| Cai, DS | 1 |
| Schiffman, HJ | 2 |
| Olufs, ZPG | 2 |
| Lasarev, MR | 1 |
| Wassarman, DA | 2 |
| Perouansky, M | 2 |
| Fortea, JI | 1 |
| Puerto, M | 1 |
| Fernández-Mena, C | 1 |
| Asensio, I | 1 |
| Arriba, M | 1 |
| Almagro, J | 1 |
| Bañares, J | 1 |
| Ripoll, C | 1 |
| Bañares, R | 1 |
| Vaquero, J | 1 |
| Altay, O | 1 |
| Suzuki, H | 1 |
| Altay, BN | 1 |
| Calisir, V | 1 |
| Tang, J | 1 |
| Zhang, JH | 1 |
| Lotz, C | 1 |
| Stumpner, J | 1 |
| Smul, TM | 1 |
| Yang, L | 2 |
| Ton, H | 1 |
| Zhao, R | 1 |
| Geron, E | 1 |
| Li, M | 4 |
| Yu, B | 2 |
| Tan, H | 1 |
| Boukhali, M | 1 |
| Khatri, A | 1 |
| Hua, F | 2 |
| Liu, L | 2 |
| Haas, W | 1 |
| Tan, J | 1 |
| Wu, Z | 1 |
| Liu, J | 5 |
| Zhang, W | 1 |
| Yuan, W | 1 |
| Peng, H | 1 |
| Liang, Z | 1 |
| Zhou, H | 2 |
| Tang, R | 1 |
| Zhang, S | 1 |
| Chen, X | 1 |
| Pei, L | 1 |
| Scharenbrock, AR | 1 |
| Cui, E | 1 |
| Zhang, H | 3 |
| Zhu, X | 1 |
| Zhou, J | 2 |
| Yan, M | 3 |
| Sun, J | 2 |
| Sun, M | 1 |
| Zhang, J | 4 |
| Feng, X | 1 |
| Chen, L | 2 |
| Zhou, R | 1 |
| Bao, X | 1 |
| Mou, H | 1 |
| Ye, L | 1 |
| Yang, P | 1 |
| Bertani, A | 1 |
| Miceli, V | 1 |
| De Monte, L | 1 |
| Occhipinti, G | 1 |
| Pagano, V | 1 |
| Liotta, R | 1 |
| Badami, E | 1 |
| Tuzzolino, F | 1 |
| Arcadipane, A | 1 |
| Wang, M | 2 |
| Zuo, Y | 2 |
| Li, X | 2 |
| Thirupathi, A | 1 |
| Yu, P | 3 |
| Gao, G | 2 |
| Zhou, C | 3 |
| Chang, Y | 1 |
| Jiang, C | 1 |
| Arzua, T | 1 |
| Yan, Y | 1 |
| Yu, L | 1 |
| Ye, X | 1 |
| Li, Z | 2 |
| Li, E | 1 |
| Li, C | 1 |
| Yu, TY | 1 |
| Gong, LR | 1 |
| Mu, R | 1 |
| Yu, JB | 1 |
| Pei, W | 1 |
| Fu, L | 1 |
| Li, SQ | 1 |
| Ngamsri, KC | 1 |
| Fabian, F | 1 |
| Fuhr, A | 1 |
| Gamper-Tsigaras, J | 1 |
| Straub, A | 2 |
| Fecher, D | 1 |
| Steinke, M | 1 |
| Walles, H | 1 |
| Reutershan, J | 1 |
| Konrad, FM | 1 |
| Xie, L | 1 |
| Fang, Q | 1 |
| Wei, X | 1 |
| Zhou, L | 1 |
| Wang, S | 2 |
| Wang, H | 4 |
| Xu, Y | 1 |
| Zhu, S | 2 |
| Yan, C | 1 |
| Ti-Jun, D | 1 |
| Xin, L | 1 |
| Gao, C | 1 |
| Shen, J | 1 |
| Hong, T | 1 |
| Zhi-Xiu, M | 1 |
| Du, G | 1 |
| Lu, H | 1 |
| Shapoval, D | 1 |
| Liu, X | 2 |
| Zhu, YM | 1 |
| Gao, X | 1 |
| Ni, Y | 1 |
| Li, W | 2 |
| Kent, TA | 1 |
| Qiao, SG | 1 |
| Wang, C | 3 |
| Xu, XX | 1 |
| Zhang, HL | 1 |
| Alvarado, MC | 2 |
| Murphy, KL | 3 |
| Baxter, MG | 3 |
| Lv, X | 2 |
| Yan, J | 1 |
| Jiang, J | 2 |
| Zhou, X | 1 |
| Lu, Y | 1 |
| Jiang, H | 2 |
| Lee, JR | 1 |
| Lin, EP | 1 |
| Hofacer, RD | 1 |
| Upton, B | 1 |
| Lee, SY | 1 |
| Ewing, L | 1 |
| Joseph, B | 1 |
| Loepke, AW | 1 |
| Perez-Zoghbi, JF | 1 |
| Zhu, W | 2 |
| Grafe, MR | 1 |
| Brambrink, AM | 1 |
| Liang, P | 1 |
| Li, F | 1 |
| Liao, D | 1 |
| Huang, H | 1 |
| Zhu, QL | 1 |
| Luo, Y | 2 |
| Xue, QS | 1 |
| Zhang, FJ | 2 |
| Yu, BW | 1 |
| Behmenburg, F | 1 |
| van Caster, P | 1 |
| Bunte, S | 1 |
| Brandenburger, T | 1 |
| Heinen, A | 1 |
| Hollmann, MW | 1 |
| Huhn, R | 1 |
| Ozturk, O | 1 |
| Ustebay, S | 1 |
| Eroglu, HA | 1 |
| Günay, M | 1 |
| Adali, Y | 1 |
| Donmez, İ | 1 |
| Erbas, M | 1 |
| Satomoto, M | 1 |
| Adachi, YU | 1 |
| Kinoshita, H | 1 |
| Makita, K | 1 |
| Liu, TJ | 3 |
| Zhang, JC | 1 |
| Gao, XZ | 3 |
| Tan, ZB | 1 |
| Wang, JJ | 1 |
| Zhang, PP | 1 |
| Cheng, AB | 1 |
| Zhang, SB | 3 |
| Parapanov, R | 1 |
| Francioli, C | 1 |
| Perentes, JY | 1 |
| Letovanec, I | 1 |
| Gonzalez, M | 1 |
| Kern, C | 1 |
| Ris, HB | 1 |
| Piquilloud, L | 1 |
| Marcucci, C | 1 |
| Krueger, T | 1 |
| Liaudet, L | 1 |
| Gronchi, F | 1 |
| Kim, HY | 1 |
| Baek, SH | 1 |
| Baik, SW | 1 |
| Bae, SS | 1 |
| Ha, JM | 1 |
| Kim, M | 1 |
| Byeon, GJ | 1 |
| Kim, HJ | 1 |
| Ri, HS | 1 |
| Kim, SH | 1 |
| Wagner, J | 1 |
| Strosing, KM | 2 |
| Spassov, SG | 1 |
| Lin, Z | 1 |
| Engelstaedter, H | 2 |
| Tacke, S | 2 |
| Hoetzel, A | 2 |
| Faller, S | 2 |
| Dong, P | 3 |
| Li, N | 3 |
| Lu, L | 2 |
| Li, L | 6 |
| Zhang, X | 3 |
| Li, D | 4 |
| Raper, J | 1 |
| De Biasio, JC | 1 |
| Pu, GH | 2 |
| Li, BY | 2 |
| Han, XL | 2 |
| Bedirli, N | 3 |
| Bagriacik, EU | 1 |
| Yilmaz, G | 1 |
| Ozkose, Z | 1 |
| Kavutçu, M | 1 |
| Cavunt Bayraktar, A | 1 |
| Bedirli, A | 3 |
| Irwin, MG | 1 |
| Zhang, Q | 1 |
| Duan, X | 1 |
| Yamada, T | 2 |
| Nagata, H | 1 |
| Kosugi, S | 1 |
| Suzuki, T | 2 |
| Morisaki, H | 1 |
| Kotake, Y | 1 |
| Sánchez-Pedrosa, G | 1 |
| Vara Ameigeiras, E | 1 |
| Casanova Barea, J | 1 |
| Rancan, L | 1 |
| Simón Adiego, CM | 1 |
| Garutti Martínez, I | 1 |
| Wang, WF | 1 |
| Li, YH | 1 |
| Li, LS | 1 |
| Guo, X | 1 |
| Liu, R | 2 |
| Zha, B | 1 |
| Shen, Q | 1 |
| Zou, H | 1 |
| Cheng, C | 1 |
| Wu, H | 2 |
| Li, WC | 1 |
| Gao, H | 2 |
| Wang, ZJ | 1 |
| Grievink, H | 1 |
| Kuzmina, N | 1 |
| Chevion, M | 1 |
| Drenger, B | 1 |
| Sima, LJ | 1 |
| Ma, XW | 1 |
| Zhao, YB | 1 |
| Zhang, LJ | 1 |
| Shan, RG | 1 |
| Sun, ZZ | 1 |
| Wang, K | 1 |
| Chen, JQ | 1 |
| Mu, JX | 1 |
| Fei, J | 1 |
| Kazuma, S | 1 |
| Tokinaga, Y | 1 |
| Kimizuka, M | 1 |
| Azumaguchi, R | 1 |
| Hamada, K | 1 |
| Yamakage, M | 2 |
| Huang, G | 1 |
| Hao, F | 1 |
| Ton, HT | 1 |
| Ge, X | 1 |
| Israr, M | 1 |
| Li, B | 2 |
| Chang, YZ | 1 |
| Su, R | 1 |
| Sun, P | 1 |
| Zhang, D | 1 |
| Xiao, W | 1 |
| Feng, C | 1 |
| Zhong, L | 1 |
| Wang, N | 3 |
| Ferrando, C | 1 |
| Aguilar, G | 1 |
| Piqueras, L | 1 |
| Soro, M | 1 |
| Moreno, J | 1 |
| Belda, FJ | 1 |
| Brosnan, H | 1 |
| Bickler, PE | 1 |
| Seubert, CN | 1 |
| Pavlinec, C | 1 |
| Gravenstein, N | 1 |
| Martynyuk, AE | 1 |
| Zhou, SP | 1 |
| Jiang, P | 1 |
| Liu, H | 1 |
| Herrmann, IK | 2 |
| Castellon, M | 1 |
| Schwartz, DE | 1 |
| Hasler, M | 2 |
| Urner, M | 2 |
| Hu, G | 1 |
| Minshall, RD | 2 |
| Beck-Schimmer, B | 4 |
| Xu, H | 2 |
| Lu, B | 1 |
| Zheng, B | 2 |
| Qi, B | 1 |
| Deng, Y | 1 |
| He, Z | 2 |
| Su, D | 1 |
| Terai, T | 1 |
| Osawa, S | 1 |
| Tani, S | 1 |
| Oishi, S | 1 |
| Arai, Y | 1 |
| Sugimoto, M | 1 |
| Furuta, T | 1 |
| Kanaoka, S | 1 |
| Miyajima, H | 1 |
| Sugimoto, K | 1 |
| Yao, Y | 2 |
| Zhao, S | 1 |
| Wu, J | 2 |
| Ai, Y | 1 |
| Dong, J | 1 |
| Lei, W | 1 |
| Wang, JK | 1 |
| Wu, HF | 1 |
| Liu, XZ | 1 |
| Lv, G | 1 |
| Wang, G | 2 |
| Xie, K | 2 |
| Jiao, Y | 1 |
| Knapp, J | 1 |
| Teschendorf, P | 1 |
| Scholz, E | 1 |
| Roewer, J | 1 |
| Russ, N | 1 |
| Böttiger, BW | 1 |
| Popp, E | 1 |
| Amrock, LG | 1 |
| Starner, ML | 1 |
| Xie, H | 1 |
| Zhu, J | 1 |
| Liu, LX | 1 |
| Rebecchi, M | 1 |
| Hu, SM | 1 |
| Miura, Y | 1 |
| Kanazawa, K | 1 |
| Nasu, I | 1 |
| Shen, QY | 2 |
| Fang, L | 2 |
| Wu, HM | 2 |
| He, F | 2 |
| Ding, PS | 1 |
| Liu, RY | 2 |
| Shan, Z | 1 |
| Cai, S | 1 |
| Zhang, T | 1 |
| Kuang, L | 1 |
| Xiu, H | 1 |
| Wen, J | 1 |
| Gu, H | 1 |
| Xu, K | 1 |
| Bartos, JA | 1 |
| Matsuura, TR | 1 |
| Sarraf, M | 1 |
| Youngquist, ST | 1 |
| McKnite, SH | 1 |
| Rees, JN | 1 |
| Sloper, DT | 1 |
| Bates, FS | 1 |
| Segal, N | 1 |
| Debaty, G | 1 |
| Lurie, KG | 1 |
| Neumar, RW | 1 |
| Metzger, JM | 1 |
| Riess, ML | 1 |
| Yannopoulos, D | 1 |
| Umezawa, N | 1 |
| Arisaka, H | 1 |
| Sakuraba, S | 1 |
| Sugita, T | 1 |
| Matsumoto, A | 1 |
| Kaku, Y | 1 |
| Yoshida, K | 1 |
| Kuwana, S | 1 |
| Chen, C | 2 |
| Ji, M | 1 |
| Xu, Q | 2 |
| Sun, Q | 1 |
| Schläpfer, M | 2 |
| Schimmer, RR | 1 |
| Booy, C | 3 |
| Roth Z'graggen, B | 2 |
| Rehrauer, H | 1 |
| Aigner, F | 1 |
| Stark, WJ | 1 |
| Chung, W | 1 |
| Park, S | 2 |
| Hong, J | 1 |
| Lee, S | 1 |
| Heo, J | 1 |
| Kim, D | 1 |
| Ko, Y | 1 |
| Rocha, TL | 1 |
| Dias-Junior, CA | 1 |
| Possomato-Vieira, JS | 1 |
| Gonçalves-Rizzi, VH | 1 |
| Nogueira, FR | 1 |
| de Souza, KM | 1 |
| Braz, LG | 2 |
| Braz, MG | 1 |
| Yu, S | 1 |
| Yuan, L | 1 |
| Zhou, Z | 1 |
| Liu, Q | 1 |
| Du, X | 1 |
| Chen, S | 1 |
| Lai, Z | 1 |
| Su, J | 1 |
| Cai, D | 1 |
| Wang, WY | 1 |
| Wu, XM | 1 |
| Jia, LJ | 1 |
| Zhang, HH | 1 |
| Cai, F | 1 |
| Mao, H | 1 |
| Xu, WC | 1 |
| Hu, SF | 1 |
| Chen, D | 1 |
| Fang, N | 1 |
| Hsiao, HT | 1 |
| Huang, PC | 1 |
| Tsai, YC | 1 |
| Liu, YC | 1 |
| Zhan, Q | 1 |
| Chen, J | 2 |
| Wu, L | 1 |
| van den Brom, CE | 1 |
| Boly, CA | 1 |
| Bulte, CS | 1 |
| van den Akker, RF | 1 |
| Kwekkeboom, RF | 1 |
| Loer, SA | 1 |
| Boer, C | 1 |
| Bouwman, RA | 1 |
| Hu, N | 1 |
| Zheng, Y | 1 |
| Ao, J | 1 |
| Zhang, C | 1 |
| Gyllenram, V | 1 |
| Buerkle, H | 1 |
| Spassov, S | 1 |
| Cheng, X | 1 |
| Hou, J | 1 |
| Sun, X | 1 |
| Sheng, Q | 1 |
| Han, P | 1 |
| Kang, YJ | 1 |
| Xu, Z | 1 |
| Yu, J | 2 |
| Wang, Z | 2 |
| Kim, HC | 1 |
| Kim, E | 1 |
| Bae, JI | 1 |
| Lee, KH | 1 |
| Jeon, YT | 1 |
| Hwang, JW | 1 |
| Lim, YJ | 1 |
| Min, SW | 1 |
| Park, HP | 1 |
| Ringer, SK | 1 |
| Ohlerth, S | 1 |
| Carrera, I | 1 |
| Mauch, J | 1 |
| Spielmann, N | 1 |
| Bettschart-Wolfensberger, R | 1 |
| Weiss, M | 1 |
| Granja, TF | 1 |
| Köhler, D | 1 |
| Schad, J | 1 |
| de Oliveira, CB | 1 |
| Konrad, F | 1 |
| Hoch-Gutbrod, M | 1 |
| Streienberger, A | 1 |
| Rosenberger, P | 1 |
| Tian, D | 1 |
| Tian, M | 1 |
| Ma, Z | 1 |
| Cui, Y | 1 |
| Maimaitili, Y | 1 |
| Xie, P | 1 |
| Wu, JJ | 1 |
| Yang, YN | 1 |
| Ma, HP | 1 |
| Zheng, H | 1 |
| Esser, T | 1 |
| Keilhoff, G | 1 |
| Ebmeyer, U | 1 |
| Ryu, YK | 1 |
| Mathena, RP | 1 |
| Lim, S | 1 |
| Kwak, M | 1 |
| Xu, M | 1 |
| Mintz, CD | 1 |
| Kellner, P | 1 |
| Müller, M | 1 |
| Piegeler, T | 1 |
| Eugster, P | 1 |
| Zhang, LM | 1 |
| Zhang, DX | 1 |
| Zhao, XC | 1 |
| Sun, WB | 1 |
| Jiang, XJ | 1 |
| Cai, M | 1 |
| Tong, L | 1 |
| Dong, B | 1 |
| Hou, W | 1 |
| Shi, L | 1 |
| Dong, H | 1 |
| Wu, Y | 1 |
| Yu, X | 1 |
| Han, X | 1 |
| Fan, L | 1 |
| Wu, X | 1 |
| Saiyin, H | 1 |
| Xie, J | 1 |
| Ma, L | 1 |
| Xue, L | 1 |
| Liang, W | 2 |
| Yu, Q | 2 |
| Hang, L | 1 |
| Shao, D | 1 |
| Sun, W | 1 |
| Dai, T | 1 |
| Zeng, Y | 2 |
| Ma, D | 1 |
| Ieong, E | 1 |
| Sanders, RD | 1 |
| Hossain, M | 1 |
| Maze, M | 1 |
| Larsen, JR | 3 |
| Aagaard, S | 1 |
| Lie, RH | 1 |
| Sloth, E | 3 |
| Hasenkam, JM | 3 |
| Chen, Q | 1 |
| Song, WY | 1 |
| Ma, R | 1 |
| Xiong, LZ | 1 |
| Cabañero, D | 1 |
| Célérier, E | 1 |
| García-Nogales, P | 1 |
| Mata, M | 1 |
| Roques, BP | 1 |
| Maldonado, R | 1 |
| Puig, MM | 1 |
| Silva, AE | 1 |
| Castiglia, YM | 1 |
| Módolo, NS | 1 |
| Roberto, WM | 1 |
| Vane, LA | 1 |
| Vianna, PT | 1 |
| Braz, JR | 1 |
| Richebé, P | 1 |
| Rivalan, B | 1 |
| Rivat, C | 1 |
| Laulin, JP | 1 |
| Janvier, G | 1 |
| Maurette, P | 1 |
| Simonnet, G | 1 |
| Smerup, M | 1 |
| Christensen, SD | 1 |
| Sivesgaard, K | 1 |
| Torp, P | 1 |
| Zhang, F | 1 |
| Chen, G | 1 |
| Zhang, G | 1 |
| Zhang, B | 1 |
| Moir, RD | 1 |
| Xia, W | 1 |
| Marcantonio, ER | 1 |
| Culley, DJ | 1 |
| Crosby, G | 1 |
| Tanzi, RE | 1 |
| Wang, JM | 1 |
| Hu, ZY | 2 |
| Gu, WZ | 1 |
| Ding, Q | 1 |
| Deng, J | 1 |
| Gu, Q | 1 |
| Hu, S | 1 |
| Su, B | 1 |
| Xiong, L | 2 |
| Karanovic, N | 1 |
| Pecotic, R | 1 |
| Valic, M | 1 |
| Jeroncic, A | 1 |
| Carev, M | 1 |
| Karanovic, S | 1 |
| Ujevic, A | 1 |
| Dogas, Z | 1 |
| Lin, HF | 1 |
| Zhu, ZR | 1 |
| Imoto, A | 1 |
| Yokoyama, T | 1 |
| Suwa, K | 1 |
| Yamasaki, F | 1 |
| Yatabe, T | 1 |
| Yokoyama, R | 1 |
| Yamashita, K | 1 |
| Selldén, E | 1 |
| Kanazawa, M | 1 |
| Ando, S | 1 |
| Tsuda, M | 1 |
| Aptekman, B | 1 |
| Tarashansky, M | 1 |
| Sotman, A | 1 |
| Khoury, W | 1 |
| Khuri, W | 1 |
| Ben-Abraham, R | 1 |
| Dolkart, O | 1 |
| Weinbroum, AA | 1 |
| Pal, D | 2 |
| Lipinski, WJ | 2 |
| Walker, AJ | 1 |
| Turner, AM | 1 |
| Mashour, GA | 2 |
| Regueiro-Purriños, M | 1 |
| Fernández-Vázquez, F | 1 |
| de Prado, AP | 1 |
| Altónaga, JR | 1 |
| Cuellas-Ramón, C | 1 |
| Ajenjo-Silverio, JM | 1 |
| Orden, A | 1 |
| Gonzalo-Orden, JM | 1 |
| Boscan, P | 1 |
| Monnet, E | 1 |
| Mama, K | 1 |
| Twedt, DC | 1 |
| Congdon, J | 1 |
| Eickhoff, JC | 1 |
| Steffey, EP | 1 |
| Iwasaki, S | 1 |
| Watanabe, A | 1 |
| Chu, M | 1 |
| Lu, S | 1 |
| Li, P | 1 |
| Gan, Y | 1 |
| Shi, H | 1 |
| Ye, Z | 2 |
| Guo, Q | 2 |
| Xia, P | 2 |
| Yuan, Y | 2 |
| Wang, E | 2 |
| Albrecht, M | 2 |
| Gruenewald, M | 2 |
| Zitta, K | 2 |
| Zacharowski, K | 1 |
| Scholz, J | 2 |
| Bein, B | 2 |
| Meybohm, P | 2 |
| Müller, C | 1 |
| Foesel, N | 1 |
| Maracke, M | 1 |
| Schrezenmeir, J | 1 |
| Kitamura, T | 1 |
| Sato, K | 1 |
| Kawamura, G | 1 |
| Yamada, Y | 1 |
| Walton, ME | 1 |
| Koch, LG | 1 |
| Lydic, R | 1 |
| Britton, SL | 1 |
| Gauberti, M | 1 |
| Obiang, P | 1 |
| Guedin, P | 1 |
| Balossier, A | 1 |
| Gakuba, C | 1 |
| Diependaele, AS | 1 |
| Chazalviel, L | 1 |
| Vivien, D | 1 |
| Young, AR | 1 |
| Agin, V | 1 |
| Orset, C | 1 |
| Demirtas, CY | 1 |
| Akkaya, T | 1 |
| Salman, B | 1 |
| Alper, M | 2 |
| Pasaoglu, H | 2 |
| Tai, W | 1 |
| Shi, E | 1 |
| Yan, L | 1 |
| Jiang, X | 1 |
| Ai, C | 1 |
| Annecke, T | 2 |
| Rehm, M | 2 |
| Bruegger, D | 1 |
| Kubitz, JC | 2 |
| Kemming, GI | 2 |
| Stoeckelhuber, M | 1 |
| Stoekelhuber, M | 1 |
| Becker, BF | 1 |
| Conzen, PF | 2 |
| Fortis, S | 1 |
| Spieth, PM | 1 |
| Lu, WY | 1 |
| Parotto, M | 1 |
| Haitsma, JJ | 1 |
| Slutsky, AS | 1 |
| Zhong, N | 1 |
| Mazer, CD | 1 |
| Ye, R | 1 |
| Yang, Q | 1 |
| Kong, X | 1 |
| Han, J | 1 |
| Liu, HG | 1 |
| Hua, Z | 1 |
| Wang, YX | 1 |
| Meng, C | 1 |
| Liang, Y | 1 |
| Tian, SY | 1 |
| Ma, YP | 1 |
| Wang, WS | 1 |
| Ma, LL | 1 |
| Yonamine, R | 1 |
| Satoh, Y | 1 |
| Kodama, M | 1 |
| Araki, Y | 1 |
| Kazama, T | 1 |
| Chaves, AA | 1 |
| Dech, SJ | 1 |
| Nakayama, T | 1 |
| Hamlin, RL | 1 |
| Bauer, JA | 1 |
| Carnes, CA | 1 |
| Holmström, A | 1 |
| Rosén, I | 1 |
| Akeson, J | 1 |
| Payne, RS | 1 |
| Akca, O | 1 |
| Roewer, N | 1 |
| Schurr, A | 1 |
| Kehl, F | 1 |
| Kandatsu, N | 1 |
| Nan, YS | 1 |
| Feng, GG | 1 |
| Nishiwaki, K | 1 |
| Hirokawa, M | 1 |
| Ishikawa, K | 1 |
| Komatsu, T | 1 |
| Yokochi, T | 1 |
| Shimada, Y | 1 |
| Ishikawa, N | 1 |
| Erdem, AF | 1 |
| Cesur, M | 1 |
| Alici, HA | 1 |
| Erdogan, F | 1 |
| Dogan, N | 1 |
| Kursad, H | 1 |
| Yuksek, MS | 1 |
| Kerbaul, F | 1 |
| Bellezza, M | 1 |
| Mekkaoui, C | 1 |
| Feier, H | 1 |
| Guidon, C | 1 |
| Gouvernet, J | 1 |
| Rolland, PH | 1 |
| Gouin, F | 1 |
| Mesana, T | 1 |
| Collart, F | 1 |
| Karwacki, Z | 1 |
| Kowiański, P | 1 |
| Dziewiatkowski, J | 1 |
| Domaradzka-Pytel, B | 1 |
| Ludkiewicz, B | 1 |
| Wójcik, S | 1 |
| Narkiewicz, O | 1 |
| Moryś, J | 1 |
| Rodríguez-López, JM | 1 |
| Sánchez-Conde, P | 1 |
| Lozano, FS | 1 |
| Nicolás, JL | 1 |
| García-Criado, FJ | 1 |
| Cascajo, C | 1 |
| Muriel, C | 1 |
| Burburan, SM | 1 |
| Xisto, DG | 1 |
| Ferreira, HC | 1 |
| Riva, Ddos R | 1 |
| Carvalho, GM | 1 |
| Zin, WA | 1 |
| Rocco, PR | 1 |
| Engelhard, K | 1 |
| Winkelheide, U | 1 |
| Werner, C | 1 |
| Kluge, J | 1 |
| Eberspächer, E | 1 |
| Hollweck, R | 1 |
| Hutzler, P | 1 |
| Winkler, J | 1 |
| Kochs, E | 1 |
| Aagaard, SR | 1 |
| Hang, LH | 1 |
| Shao, DH | 1 |
| Yang, YH | 1 |
| Dai, TJ | 1 |
| Zeng, YM | 1 |
| Yue, T | 1 |
| Blumenthal, S | 1 |
| Neff, SB | 1 |
| Reyes, L | 1 |
| Steurer, M | 1 |
| Spahn, DR | 1 |
| Neff, TA | 1 |
| Schmid, ER | 1 |
| Kaneda, K | 1 |
| Miyamae, M | 1 |
| Sugioka, S | 1 |
| Okusa, C | 1 |
| Inamura, Y | 1 |
| Domae, N | 1 |
| Kotani, J | 1 |
| Figueredo, VM | 1 |
| Ofluoglu, E | 1 |
| Kerem, M | 1 |
| Utebey, G | 1 |
| Yilmazer, D | 1 |
| Ozlu, O | 1 |
| Langer, K | 1 |
| Hilberath, JM | 1 |
| Kahr, S | 1 |
| Krombach, F | 1 |
| Bittmann, I | 1 |
| Pagel, PS | 1 |
| Ebert, TJ | 1 |
| Harkin, CP | 1 |
| Muzi, M | 1 |
| Kenna, JG | 1 |
| Jones, RM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Dexmedetomidine on Cognitive Outcome and Brain Injury Markers After General Anesthesia for Cardiac Surgery on Cardiopulmonary Bypass[NCT03585452] | 23 participants (Actual) | Interventional | 2018-08-01 | Completed | |||
| Effect of a Perioperative Opioid Free Anaesthesia-Analgesia (OFA-A) Strategy on Surgical Stress Response and Immunomodulation in Elective VATS Lobectomy for NSCLC Lung Cancer: A Prospective Randomized Study[NCT05172739] | Phase 4 | 70 participants (Anticipated) | Interventional | 2021-10-01 | Recruiting | ||
| AnaConDa-therapy in COVID-19 Patients[NCT05586126] | 42 participants (Actual) | Observational | 2020-10-01 | Terminated (stopped due to Concerns about possible association between drug and increased ICU mortality) | |||
| Volatile Anesthetic Pharmacokinetics During Extracorporeal Membrane[NCT05680545] | 10 participants (Anticipated) | Interventional | 2024-07-01 | Not yet recruiting | |||
| A Randomized Pilot Clinical Trial of the Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction of Sevoflurane in Patient's Whit ARDS Secondary to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2)[NCT04998253] | Early Phase 1 | 24 participants (Actual) | Interventional | 2020-10-01 | Completed | ||
| Effects of General Anesthesia on Brain Functional Connectivity and Cognition in Children With Potential Neurological Damage[NCT05602311] | 120 participants (Anticipated) | Observational [Patient Registry] | 2022-08-15 | Recruiting | |||
| Subanesthetic Sevoflurane for Treatment-Resistant Depression: A Proof-of-Concept Trial[NCT05008939] | 15 participants (Anticipated) | Interventional | 2021-08-31 | Not yet recruiting | |||
| Sevoflurane Sedation: A Potentially Promising Immunomodulation in Patients With Septic Shock[NCT03643367] | Phase 2 | 153 participants (Anticipated) | Interventional | 2025-01-31 | Not yet recruiting | ||
| Digestive ENdoscopy afTeR Out-of-hospitAl Cardiac arresT[NCT02349074] | 221 participants (Actual) | Interventional | 2014-11-12 | Completed | |||
| Effect of Sevoflurane-induced Postconditioning on the Incidence of Postoperative Cerebral Hyperperfusion Syndrome After Revascularization Surgery in Adult Patients With Moyamoya Disease[NCT02510586] | 152 participants (Anticipated) | Interventional | 2015-08-31 | Not yet recruiting | |||
| Sevoflurane Sedation in COVID-19 ARDS Patients to Reduce Lung Injury: a Randomized Controlled Trial[NCT04355962] | Phase 3 | 68 participants (Actual) | Interventional | 2020-04-23 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for sevoflurane and Disease Models, Animal
| Article | Year |
|---|---|
Cardiovascular responses to sevoflurane: a review.
Topics: Adult; Anesthetics, Inhalation; Animals; Baroreflex; Blood Pressure; Cardiovascular System; Cerebrov | 1995 |
The organ toxicity of inhaled anesthetics.
Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Disease Models | 1995 |
1 trial available for sevoflurane and Disease Models, Animal
| Article | Year |
|---|---|
Ventricular arrhythmias and mortality associated with isoflurane and sevoflurane in a porcine model of myocardial infarction.
Topics: Anesthetics, Inhalation; Animal Welfare; Animals; Arrhythmias, Cardiac; Disease Models, Animal; Fema | 2011 |
185 other studies available for sevoflurane and Disease Models, Animal
| Article | Year |
|---|---|
Sevoflurane and isoflurane inhibit KCl-induced, Rho kinase-mediated, and PI3K-participated vasoconstriction in aged diabetic rat aortas.
Topics: Aging; Amides; Anesthetics, Inhalation; Animals; Aorta; Chromones; Diabetes Mellitus, Experimental; | 2021 |
CTRP6(C1q/Tumor Necrosis Factor (TNF)-related protein-6) alleviated the sevoflurane induced injury of mice central nervous system by promoting the expression of p-Akt (phosphorylated Akt).
Topics: Adipokines; Animals; Cells, Cultured; Central Nervous System; Cognitive Dysfunction; Disease Models, | 2021 |
Different Anesthetic Drugs Mediate Changes in Neuroplasticity During Cognitive Impairment in Sleep-Deprived Rats via Different Factors.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cognitive Dysfunction; Disease Models, A | 2021 |
METTL3 regulates hippocampal gene transcription via N6-methyladenosine methylation in sevoflurane-induced postoperative cognitive dysfunction mouse.
Topics: Adenosine; Animals; Disease Models, Animal; DNA Methylation; Female; Hippocampus; MAP Kinase Signali | 2021 |
Phosphoinositide-3-Kinase/Akt-Endothelial Nitric Oxide Synthase Signaling Pathway Mediates the Neuroprotective Effect of Sevoflurane Postconditioning in a Rat Model of Hemorrhagic Shock and Resuscitation.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Ischemic Postconditioning; Male; Neuroprot | 2022 |
Prenatal sevoflurane exposure causes abnormal development of the entorhinal cortex in rat offspring.
Topics: Animals; Disease Models, Animal; Entorhinal Cortex; Female; GABA-A Receptor Agonists; Interneurons; | 2021 |
Testosterone attenuates sevoflurane-induced tau phosphorylation and cognitive impairment in neonatal male mice.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cognitive Dysfunction; Disease Models, Animal; M | 2021 |
Prolonged Volatile Anesthetic Exposure Exacerbates Cognitive Impairment and Neuropathology in the 5xFAD Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Anesthetics, Inhalation; Animals; Cognitive Dysfunction; Disease Models, Animal; | 2021 |
Sevoflurane protects against cerebral ischemia/reperfusion injury via microrna-30c-5p modulating homeodomain-interacting protein kinase 1.
Topics: Animals; Base Sequence; Brain Ischemia; Cell Line; Disease Models, Animal; Down-Regulation; Glucose; | 2021 |
Assessments of prolonged effects of desflurane and sevoflurane on motor learning deficits in aged App
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Desflurane; | 2022 |
Sevoflurane Induces Neurotoxicity in the Animal Model with Alzheimer's Disease Neuropathology via Modulating Glutamate Transporter and Neuronal Apoptosis.
Topics: Alzheimer Disease; Amino Acid Transport System X-AG; Anesthetics, Inhalation; Animals; Apoptosis; Di | 2022 |
Immunomodulatory roles of propofol and sevoflurane in murine models of breast cancer.
Topics: Animals; Breast Neoplasms; Disease Models, Animal; Female; Humans; Methyl Ethers; Mice; Propofol; Se | 2023 |
Knocking down Trim47 ameliorated sevoflurane-induced neuronal cell injury and cognitive impairment in rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Cognition; Cognitive Dysfunction; Disease Models, Anima | 2023 |
Sevoflurane suppresses the malignant progression of breast cancer via the hsa_circ_0000129/miR-578/EPSTI1 axis.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Count; Cell Proliferation; Disease Models, Animal; Female | 2023 |
Sevoflurane Preconditioning Prevents Septic Myocardial Dysfunction in Lipopolysaccharide-Challenged Mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Disease Models, Animal; Drug Administrat | 2019 |
Effect of sevoflurane pretreatment in relieving liver ischemia/reperfusion-induced pulmonary and hepatic injury.
Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Disease Models, | 2019 |
Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Disease Models, Animal; Interleukin-6; Intestinal Mucos | 2020 |
Sevoflurane attenuates brain damage through inhibiting autophagy and apoptosis in cerebral ischemia‑reperfusion rats.
Topics: Animals; Apoptosis; Cerebral Cortex; Disease Models, Animal; Male; Neurons; Rats; Rats, Sprague-Dawl | 2020 |
Sevoflurane postconditioning improves spatial learning and memory ability involving mitochondrial permeability transition pore in hemorrhagic shock and resuscitation rats.
Topics: Animals; Apoptosis; Disease Models, Animal; Ischemic Postconditioning; Male; Memory; Mitochondrial P | 2020 |
Sevoflurane improves circulatory function and pulmonary fibrosis in rats with pulmonary arterial hypertension through inhibiting NF-κB signaling pathway.
Topics: Administration, Inhalation; Animals; Disease Models, Animal; Down-Regulation; Humans; I-kappa B Prot | 2019 |
Distinct effects of general anesthetics on lung metastasis mediated by IL-6/JAK/STAT3 pathway in mouse models.
Topics: Anesthetics, General; Animals; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; H | 2020 |
A subanesthetic dose of sevoflurane combined with oxygen exerts bactericidal effects and prevents lung injury through the nitric oxide pathway during sepsis.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage F | 2020 |
Sevoflurane inhibits neuronal apoptosis and expressions of HIF-1 and HSP70 in brain tissues of rats with cerebral ischemia/reperfusion injury.
Topics: Animals; Apoptosis; Brain; Disease Models, Animal; HSP70 Heat-Shock Proteins; Hypoxia-Inducible Fact | 2020 |
Ageing and genetic background influence anaesthetic effects in a D. melanogaster model of blunt trauma with brain injury
Topics: Aging; Anesthetics, Inhalation; Animals; Brain; Brain Injuries, Traumatic; Disease Models, Animal; D | 2020 |
Sevoflurane versus ketamine+diazepam anesthesia for assessing systemic and hepatic hemodynamics in rats with non-cirrhotic portal hypertension.
Topics: Anesthesia, Inhalation; Anesthesiology; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; | 2020 |
Isoflurane versus sevoflurane for early brain injury and expression of sphingosine kinase 1 after experimental subarachnoid hemorrhage.
Topics: Animals; Apoptosis; Brain Edema; Disease Models, Animal; Isoflurane; Male; Mice; Neuroprotective Age | 2020 |
Sevoflurane as opposed to propofol anesthesia preserves mitochondrial function and alleviates myocardial ischemia/reperfusion injury.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Disease Models, Animal; Electron Transpo | 2020 |
Sevoflurane induces neuronal activation and behavioral hyperactivity in young mice.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Behavior, Animal; Disease Models, Animal; | 2020 |
Tau Contributes to Sevoflurane-induced Neurocognitive Impairment in Neonatal Mice.
Topics: Age Factors; Anesthetics, Inhalation; Animals; Animals, Newborn; Brain; Cognitive Dysfunction; Disea | 2020 |
MicroRNA-203-mediated inhibition of doublecortin underpins cardioprotection conferred by sevoflurane in rats after myocardial ischaemia-reperfusion injury.
Topics: Animals; Antagomirs; Cardiotonic Agents; Disease Models, Animal; Doublecortin Domain Proteins; Doubl | 2020 |
Autologous transplantation of adipose-derived stromal cells combined with sevoflurane ameliorates acute lung injury induced by cecal ligation and puncture in rats.
Topics: Acute Lung Injury; Adipose Tissue; Animals; Bronchoalveolar Lavage Fluid; Cecum; Cell- and Tissue-Ba | 2020 |
Interactions among Genetic Background, Anesthetic Agent, and Oxygen Concentration Shape Blunt Traumatic Brain Injury Outcomes in
Topics: Anesthetics, Inhalation; Animals; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Drosophi | 2020 |
Dexmedetomidine attenuates sevoflurane‑induced neurocognitive impairment through α2‑adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Caspase 3; Cognitive Dysfunction; Dexmedetomidine; | 2021 |
Dexmedetomidine and Clonidine Attenuate Sevoflurane-Induced Tau Phosphorylation and Cognitive Impairment in Young Mice via α-2 Adrenergic Receptor.
Topics: Adrenergic alpha-2 Receptor Agonists; Age Factors; Animals; Behavior, Animal; Clonidine; Cognition; | 2021 |
Blocking the Mineralocorticoid Receptor Improves Cognitive Impairment after Anesthesia/Splenectomy in Rats.
Topics: Administration, Inhalation; Administration, Oral; Anesthesia, Inhalation; Animals; Disease Models, A | 2021 |
Donor Preconditioning with Inhaled Sevoflurane Mitigates the Effects of Ischemia-Reperfusion Injury in a Swine Model of Lung Transplantation.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Disease Models, Animal; Ischemic Preco | 2021 |
Effect of sevoflurane on iron homeostasis and toxicity in the brain of mice.
Topics: Animals; Brain; Cognition; Disease Models, Animal; Homeostasis; Iron; Iron Deficiencies; Male; Mice, | 2021 |
Expression Signature of lncRNAs and mRNAs in Sevoflurane-Induced Mouse Brain Injury: Implication of Involvement of Wide Molecular Networks and Pathways.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Child Development; Computational Biology; Disease Model | 2021 |
Sevoflurane protects the liver from ischemia-reperfusion injury by regulating Nrf2/HO-1 pathway.
Topics: Animals; Apoptosis; Cell Line; Disease Models, Animal; Heme Oxygenase (Decyclizing); Heme Oxygenase- | 2021 |
Involvement of Nrf-2/HO-1 pathway in sevoflurane-induced cognitive improvement in rats with traumatic brain injury.
Topics: Anesthetics, Inhalation; Animals; Behavior, Animal; Brain Injuries, Traumatic; Cognitive Dysfunction | 2021 |
Brain transcriptomics of nonhuman primates: A review.
Topics: Aging; Animals; Brain; Brain Diseases; Disease Models, Animal; Ethanol; Humans; Methamphetamine; Neu | 2021 |
Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Hypoxia-Inducible Factor 1; Male; Mice; Mi | 2021 |
Exogenous insulin-like growth factor 1 attenuates sevoflurane anesthesia-induced cognitive dysfunction in aged rats.
Topics: Aging; Anesthetics, Inhalation; Animals; Behavior, Animal; Disease Models, Animal; Down-Regulation; | 2021 |
Post-Treatment Sevoflurane Protects Against Hypoxic-Ischemic Brain Injury in Neonatal Rats by Downregulating Histone Methyltransferase G9a and Upregulating Nuclear Factor Erythroid 2-Related Factor 2 (NRF2).
Topics: Animals; Animals, Newborn; Behavior, Animal; Cerebral Infarction; Disease Models, Animal; Gene Expre | 2021 |
5-HT1A Receptors Mediate Analgesia Induced by Emulsified Sevoflurane in Thermal Nociception but Have Little Effect on Chemical Nociception.
Topics: Aminopyridines; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Femal | 2017 |
Sevoflurane Posttreatment Attenuates Lung Injury Induced by Oleic Acid in Dogs.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Animals; Arterial Pressure; Cytoprotection; Disease Mode | 2017 |
Coenzyme Q10 reduces sevoflurane-induced cognitive deficiency in young mice.
Topics: Anesthetics, Inhalation; Animals; Cognition Disorders; Disease Models, Animal; Female; Male; Mice; M | 2017 |
Sevoflurane postconditioning attenuates reactive astrogliosis and glial scar formation after ischemia-reperfusion brain injury.
Topics: Animals; Astrocytes; Brain Ischemia; Cells, Cultured; Disease Models, Animal; Glial Fibrillary Acidi | 2017 |
Visual recognition memory is impaired in rhesus monkeys repeatedly exposed to sevoflurane in infancy.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Disease Models, Animal; Female; Macaca mulatta; | 2017 |
MicroRNA-27a-3p suppression of peroxisome proliferator-activated receptor-γ contributes to cognitive impairments resulting from sevoflurane treatment.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Cells, Cultured; Cognition Disorders; | 2017 |
Alternative technique or mitigating strategy for sevoflurane-induced neurodegeneration: a randomized controlled dose-escalation study of dexmedetomidine in neonatal rats.
Topics: Anesthetics, Inhalation; Animals; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationshi | 2017 |
Dexmedetomidine-mediated neuroprotection against sevoflurane-induced neurotoxicity extends to several brain regions in neonatal rats.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Brain; Dexmedetomidine; Disease Model | 2017 |
Sevoflurane activates hippocampal CA3 kainate receptors (Gluk2) to induce hyperactivity during induction and recovery in a mouse model.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Disease Models, Animal; GluK2 Kainate | 2017 |
Different doses of sevoflurane facilitate and impair learning and memory function through activation of the ERK pathway and synthesis of ARC protein in the rat hippocampus.
Topics: AIDS-Related Complex; Anesthetics, Inhalation; Animals; Butadienes; Disease Models, Animal; Dose-Res | 2018 |
Impact of Anesthetic Regimen on Remote Ischemic Preconditioning in the Rat Heart In Vivo.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Disease Models, Anim | 2018 |
An experimental study of ascorbic acid effects in acute renal failure under general anesthesia.
Topics: Acute Kidney Injury; Anesthesia, General; Anesthetics, Inhalation; Animals; Ascorbic Acid; Biomarker | 2017 |
Sevoflurane preconditioning ameliorates lipopolysaccharide-induced cognitive impairment in mice.
Topics: Amyloid beta-Peptides; Animals; Cognitive Dysfunction; Delirium; Disease Models, Animal; Inflammatio | 2018 |
Effect of sevoflurane on the ATPase activity of hippocampal neurons in a rat model of cerebral ischemia-reperfusion injury via the cAMP-PKA signaling pathway.
Topics: Animals; Brain-Derived Neurotrophic Factor; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP- | 2018 |
Experimental ex vivo lung perfusion with sevoflurane: effects on damaged donor lung grafts.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Extracorporeal Circulation; Lung; Lung Tra | 2018 |
The effect of sevoflurane on retinal angiogenesis in a mouse model of oxygen-induced retinopathy.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Hypoxia; Mice; Mice, Inbred C57BL; Oxygen; Retina | 2018 |
Sevoflurane posttreatment prevents oxidative and inflammatory injury in ventilator-induced lung injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Chemokine CCL4; Disease Models, Anim | 2018 |
Sevoflurane exaggerates cognitive decline in a rat model of chronic intermittent hypoxia by aggravating microglia-mediated neuroinflammation via downregulation of PPAR-γ in the hippocampus.
Topics: Anesthetics, Inhalation; Animals; Chronic Disease; Cognitive Dysfunction; Disease Models, Animal; Do | 2018 |
Persistent alteration in behavioural reactivity to a mild social stressor in rhesus monkeys repeatedly exposed to sevoflurane in infancy.
Topics: Anesthetics, Inhalation; Animals; Behavior, Animal; Disease Models, Animal; Macaca mulatta; Sevoflur | 2018 |
MicroRNA-374 Exerts Protective Effects by Inhibiting SP1 Through Activating the PI3K/Akt Pathway in Rat Models of Myocardial Ischemia-Reperfusion After Sevoflurane Preconditioning.
Topics: 3' Untranslated Regions; Animals; Antagomirs; Base Sequence; Creatine Kinase; Disease Models, Animal | 2018 |
Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis.
Topics: Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Apoptosis; bcl-2-Associated X Protein; Brai | 2018 |
Evidence of the impact of systemic inflammation on neuroinflammation from a non-bacterial endotoxin animal model.
Topics: Anesthetics, Inhalation; Animals; Body Weight; Brain; Calcium-Binding Proteins; Cytokines; Disease M | 2018 |
Postconditioning with sevoflurane ameliorates spatial learning and memory deficit via attenuating endoplasmic reticulum stress induced neuron apoptosis in a rat model of hemorrhage shock and resuscitation.
Topics: Animals; Apoptosis; Brain Ischemia; CA1 Region, Hippocampal; Disease Models, Animal; Endoplasmic Ret | 2018 |
Interaction between anesthetic conditioning and ischemic preconditioning on metabolic function after hepatic ischemia-reperfusion in rabbits.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Disease Models, Animal; Hemodynamics; Ischemic Precond | 2018 |
Role of surgical manipulation in lung inflammatory response in a model of lung resection surgery.
Topics: Anesthetics, Inhalation; Animals; Biomarkers; Cytokines; Disease Models, Animal; Inflammation; Lung; | 2018 |
Sevoflurane attenuates ventilator‑induced lung injury by regulating c‑PLA2 expression.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Biopsy; Disease Models, Animal; Female; Gene Ex | 2018 |
Suppression of Long Non-Coding RNA LINC00652 Restores Sevoflurane-Induced Cardioprotection Against Myocardial Ischemia-Reperfusion Injury by Targeting GLP-1R Through the cAMP/PKA Pathway in Mice.
Topics: 3' Untranslated Regions; Animals; Apoptosis; Cyclic AMP; Cyclic AMP Response Element-Binding Protein | 2018 |
Sevoflurane Inhibits the Th2 Response and NLRP3 Expression in Murine Allergic Airway Inflammation.
Topics: Animals; Anti-Allergic Agents; Asthma; Cytokines; Disease Models, Animal; Female; Humans; Hypersensi | 2018 |
Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Connexin 43; Disease Models, Animal; Gap Junc | 2019 |
Sevoflurane postconditioning is not mediated by ferritin accumulation and cannot be rescued by simvastatin in isolated streptozotocin-induced diabetic rat hearts.
Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Ferritins; Gene Expression Regulat | 2019 |
Effect of sevoflurane on hepatic ischemia-reperfusion injury in rats via JAK2-STAT3 pathway.
Topics: Administration, Inhalation; Animals; Cytokines; Disease Models, Animal; Janus Kinase 2; Liver; Liver | 2019 |
MicroRNA-370 protects against myocardial ischemia/reperfusion injury in mice following sevoflurane anesthetic preconditioning through PLIN5-dependent PPAR signaling pathway.
Topics: Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Ischemic Postconditioning; Male; Mic | 2019 |
Pioglitazone prevents sevoflurane‑induced neuroinflammation and cognitive decline in a rat model of chronic intermittent hypoxia by upregulating hippocampal PPAR‑γ.
Topics: Animals; Chronic Disease; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Hypoglycemic A | 2019 |
Sevoflurane Promotes Regeneration of the Endothelial Glycocalyx by Upregulating Sialyltransferase.
Topics: Anesthetics, Inhalation; Animals; Aorta; beta-D-Galactoside alpha 2-6-Sialyltransferase; Disease Mod | 2019 |
Downregulation of microRNA-155 stimulates sevoflurane-mediated cardioprotection against myocardial ischemia/reperfusion injury by binding to SIRT1 in mice.
Topics: 3' Untranslated Regions; Animals; Disease Models, Animal; Down-Regulation; Mice; MicroRNAs; Myocardi | 2019 |
Sevoflurane increases locomotion activity in mice.
Topics: Anesthetics, Inhalation; Animals; Body Weight; Disease Models, Animal; Drug Hypersensitivity; Eating | 2019 |
Transcriptomic analysis reveals the molecular mechanism of Alzheimer-related neuropathology induced by sevoflurane in mice.
Topics: Alzheimer Disease; Anesthetics; Animals; Cognitive Dysfunction; Computational Biology; Disease Model | 2019 |
Neuroprotective effect of miR-410-3p against sevoflurane anesthesia-induced cognitive dysfunction in rats through PI3K/Akt signaling pathway via targeting C-X-C motif chemokine receptor 5.
Topics: Anesthesia; Animals; Apoptosis; Cognitive Dysfunction; Disease Models, Animal; Down-Regulation; Hipp | 2019 |
Dexmedetomidine suppresses sevoflurane anesthesia-induced neuroinflammation through activation of the PI3K/Akt/mTOR pathway.
Topics: Anesthetics, Inhalation; Animals; Cerebral Cortex; Chromones; Cytokines; Dexmedetomidine; Disease Mo | 2019 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cell Membrane Permeability; Disease Models, Animal; He | 2013 |
Xenon neurotoxicity in rat hippocampal slice cultures is similar to isoflurane and sevoflurane.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cell Death; Disease Models, Animal; Dose-Respons | 2013 |
Developmental effects of neonatal isoflurane and sevoflurane exposure in rats.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Behavior, Animal; Disease Models, Animal; Electr | 2013 |
Protective effect of sevoflurane on hepatic ischaemia/reperfusion injury in the rat: A dose-response study.
Topics: Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotransferases; Biomarkers; Cyt | 2013 |
Volatile anesthetics improve survival after cecal ligation and puncture.
Topics: Anesthetics, Inhalation; Animals; Cecum; Desflurane; Disease Models, Animal; Inflammation; Isofluran | 2013 |
Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice.
Topics: Aging; Alzheimer Disease; Analysis of Variance; Anesthetics, Inhalation; Animals; Desflurane; Diseas | 2014 |
Induction of murine TNBS colitis is strictly controlled by a modified method using continuous inhalation anesthesia with sevoflurane.
Topics: Anesthesia, Inhalation; Anesthetics; Anesthetics, Inhalation; Animals; Biomarkers; Colitis; Cytokine | 2014 |
Delayed remote ischemic preconditioning produces an additive cardioprotection to sevoflurane postconditioning through an enhanced heme oxygenase 1 level partly via nuclear factor erythroid 2-related factor 2 nuclear translocation.
Topics: Active Transport, Cell Nucleus; Animals; Cardiotonic Agents; Cytoprotection; Disease Models, Animal; | 2014 |
Post-conditioning with sevoflurane induces heme oxygenase-1 expression via the PI3K/Akt pathway in lipopolysaccharide-induced acute lung injury.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Gene Expression Regulation; Heme Oxygenase-1; Li | 2014 |
Aging causes exacerbated ischemic brain injury and failure of sevoflurane post-conditioning: role of B-cell lymphoma-2.
Topics: Age Factors; Aging; Animals; Apoptosis; Brain; Brain Ischemia; Disease Models, Animal; Ischemic Post | 2014 |
Postconditioning with sevoflurane protects against focal cerebral ischemia and reperfusion injury involving mitochondrial ATP-dependent potassium channel and mitochondrial permeability transition pore.
Topics: Animals; Apoptosis; Brain Edema; Brain Ischemia; Disease Models, Animal; Infarction, Middle Cerebral | 2015 |
Sevoflurane postconditioning attenuates cerebral ischemia-reperfusion injury via protein kinase B/nuclear factor-erythroid 2-related factor 2 pathway activation.
Topics: Animals; Brain Infarction; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Enzyme Inhi | 2014 |
Conductance catheter measurement and effect of different anesthetics in a rat model of postresuscitation myocardial dysfunction.
Topics: Anesthetics; Animals; Cardiopulmonary Resuscitation; Disease Models, Animal; Heart Arrest; Heart Fun | 2014 |
Long-term effects of single or multiple neonatal sevoflurane exposures on rat hippocampal ultrastructure.
Topics: Anesthesia, General; Anesthetics, General; Anesthetics, Inhalation; Animals; Animals, Newborn; Disea | 2015 |
Sevoflurane post-conditioning protects isolated rat hearts against ischemia-reperfusion injury via activation of the ERK1/2 pathway.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Apoptosis Regulatory Proteins; Cardiotonic Agents; Cytop | 2014 |
Preischemic Administration of Sevoflurane Does not Exert Dose-dependent Effects on the Outcome of Severe Forebrain Ischemia in Rats.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship | 2015 |
Repeated inhalation of sevoflurane inhibits airway inflammation in an OVA-induced mouse model of allergic airway inflammation.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Disease Models, Animal; Eosino | 2015 |
Effects of sevoflurane on leucine-rich repeat kinase 2-associated Drosophila model of Parkinson's disease.
Topics: Anesthetics, Inhalation; Animals; Animals, Genetically Modified; Disease Models, Animal; Drosophila | 2015 |
Bundled postconditioning therapies improve hemodynamics and neurologic recovery after 17 min of untreated cardiac arrest.
Topics: Anesthetics, Inhalation; Animals; Cardiopulmonary Resuscitation; Coronary Circulation; Disease Model | 2015 |
Orexin-B antagonized respiratory depression induced by sevoflurane, propofol, and remifentanil in isolated brainstem-spinal cords of neonatal rats.
Topics: Anesthetics; Animals; Animals, Newborn; Brain Stem; Disease Models, Animal; Intracellular Signaling | 2015 |
Sevoflurane attenuates stress-enhanced fear learning by regulating hippocampal BDNF expression and Akt/GSK-3β signaling pathway in a rat model of post-traumatic stress disorder.
Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Fear; Glycogen Synthase Kinase 3 | 2015 |
Insight into the beneficial immunomodulatory mechanism of the sevoflurane metabolite hexafluoro-2-propanol in a rat model of endotoxaemia.
Topics: Adjuvants, Immunologic; Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Endothelial Cel | 2015 |
Sevoflurane exposure during the neonatal period induces long-term memory impairment but not autism-like behaviors.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Autistic Disorder; Behavior, Animal; | 2015 |
Sevoflurane Induces DNA Damage Whereas Isoflurane Leads to Higher Antioxidative Status in Anesthetized Rats.
Topics: Anesthetics, Inhalation; Animals; Antioxidants; Disease Models, Animal; DNA Damage; Isoflurane; Male | 2015 |
Protective Effect of Sevoflurane Postconditioning against Cardiac Ischemia/Reperfusion Injury via Ameliorating Mitochondrial Impairment, Oxidative Stress and Rescuing Autophagic Clearance.
Topics: Adenosine Triphosphate; Animals; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cardiotonic Age | 2015 |
Sevoflurane postconditioning improves long-term learning and memory of neonatal hypoxia-ischemia brain damage rats via the PI3K/Akt-mPTP pathway.
Topics: Animals; Cell Death; Disease Models, Animal; Female; Hippocampus; Hypoxia-Ischemia, Brain; Ischemic | 2016 |
Beta-arrestin1 and 2 differently modulate metabotropic glutamate receptor 7 signaling in rat developmental sevoflurane-induced neuronal apoptosis.
Topics: Animals; Apoptosis; Arrestins; Benzhydryl Compounds; beta-Arrestin 1; beta-Arrestin 2; beta-Arrestin | 2016 |
Age-associated differences in response to sevoflurane postconditioning in rats.
Topics: Age Factors; Animals; Apoptosis; Cytoprotection; Disease Models, Animal; Enzyme Activation; Extracel | 2016 |
The effect of propofol and sevoflurane on antioxidants and proinflammatory cytokines in a porcine ischemia-reperfusion model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Methyl Ethers; Myocytes, Sm | 2016 |
Sevoflurane pretreatment enhance HIF-2α expression in mice after renal ischemia/reperfusion injury.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Basic Helix-Loop-Helix Transcription Factors | 2015 |
[Effect of Toll-like receptor 2 on the inhibition role of sevoflurane on airway inflammation in asthmatic mice].
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Inflammation; Interle | 2016 |
Myocardial Perfusion and Function Are Distinctly Altered by Sevoflurane Anesthesia in Diet-Induced Prediabetic Rats.
Topics: Anesthetics, Inhalation; Animals; Coronary Circulation; Diet, Western; Disease Models, Animal; Echoc | 2016 |
The role of the Wnt/β-catenin-Annexin A1 pathway in the process of sevoflurane-induced cognitive dysfunction.
Topics: Animals; Annexin A1; beta Catenin; Cells, Cultured; Cerebellum; Cognition Disorders; Conditioning, C | 2016 |
Inhaled Anesthetics Exert Different Protective Properties in a Mouse Model of Ventilator-Induced Lung Injury.
Topics: Anesthetics, Inhalation; Animals; Anti-Inflammatory Agents; Antioxidants; Bronchoalveolar Lavage Flu | 2016 |
Safety Evaluation of Sevoflurane as Anesthetic Agent in Mouse Model of Myocardial Ischemic Infarction.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Disease Mode | 2017 |
The Effects of Two Anesthetics, Propofol and Sevoflurane, on Liver Ischemia/Reperfusion Injury.
Topics: Animals; bcl-2-Associated X Protein; Disease Models, Animal; Interleukin-1; Interleukin-6; Liver; Ma | 2016 |
Sevoflurane Postconditioning Reduces Apoptosis by Activating the JAK-STAT Pathway After Transient Global Cerebral Ischemia in Rats.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Disease Models, Animal; Ischemic Attack, Transient; Jan | 2017 |
Effects of hypotension and/or hypocapnia during sevoflurane anesthesia on perfusion and metabolites in the developing brain of piglets-a blinded randomized study.
Topics: Anesthetics, Inhalation; Animals; Aspartic Acid; Brain; Choline; Disease Models, Animal; Female; Hyp | 2016 |
Adenosine Receptor Adora2b Plays a Mechanistic Role in the Protective Effect of the Volatile Anesthetic Sevoflurane during Liver Ischemia/Reperfusion.
Topics: Adult; Anesthetics, Inhalation; Animals; Disease Models, Animal; Humans; Liver; Liver Diseases; Meth | 2016 |
Voluntary exercise rescues sevoflurane-induced memory impairment in aged male mice.
Topics: Adaptor Proteins, Signal Transducing; Analysis of Variance; Anesthetics, Inhalation; Animals; Diseas | 2016 |
High glucose concentration abrogates sevoflurane post-conditioning cardioprotection by advancing mitochondrial fission but dynamin-related protein 1 inhibitor restores these effects.
Topics: Animals; Cell Survival; Cells, Cultured; Disease Models, Animal; Dynamins; Glucose; Hyperglycemia; I | 2017 |
Anesthesia specific differences in a cardio-pulmonary resuscitation rat model; halothane versus sevoflurane.
Topics: Anesthetics, Inhalation; Animals; Asphyxia; CA1 Region, Hippocampal; Cardiopulmonary Resuscitation; | 2016 |
Sevoflurane Impairs Growth Cone Motility in Dissociated Murine Neurons.
Topics: Anesthetics, Inhalation; Animals; Cells, Cultured; Disease Models, Animal; Growth Cones; Methyl Ethe | 2016 |
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age | 2017 |
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age | 2017 |
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age | 2017 |
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age | 2017 |
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age | 2017 |
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age | 2017 |
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age | 2017 |
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age | 2017 |
Sevoflurane Abolishes Oxygenation Impairment in a Long-Term Rat Model of Acute Lung Injury.
Topics: Acute Lung Injury; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Anti-Inflammatory Age | 2017 |
Sevoflurane pre-conditioning increases phosphorylation of Erk1/2 and HO-1 expression via inhibition of mPTP in primary rat cortical neurons exposed to OGD/R.
Topics: Animals; Apoptosis; Atractyloside; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Cyclosporine; Dis | 2017 |
Kelch-like ECH-associated Protein 1-dependent Nuclear Factor-E2-related Factor 2 Activation in Relation to Antioxidation Induced by Sevoflurane Preconditioning.
Topics: Anesthetics, Inhalation; Animals; Antioxidants; Disease Models, Animal; Kelch-Like ECH-Associated Pr | 2017 |
Sevoflurane ameliorates doxorubicin-induced myocardial injury by affecting the phosphorylation states of proteins in PI3K/Akt/mTOR signaling pathway.
Topics: Animals; Apoptosis; Cardiotoxicity; Cell Line; Creatine Kinase, MB Form; Cytoprotection; Disease Mod | 2017 |
Downregulation of circulating insulin-like growth factor 1 contributes to memory impairment in aged mice after sevoflurane anesthesia.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Reg | 2017 |
Sevoflurane preconditioning induced endogenous neurogenesis against ischemic brain injury by promoting microglial activation.
Topics: Animals; Axons; Brain Injuries; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cell Differentiat | 2017 |
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors participate in the analgesic but not hypnotic effects of emulsified halogenated anaesthetics.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Anesthetics, Inhalation; Anima | 2008 |
Xenon and sevoflurane protect against brain injury in a neonatal asphyxia model.
Topics: Animals; Animals, Newborn; Asphyxia; Brain Injuries; Cell Hypoxia; Cells, Cultured; Disease Models, | 2008 |
Sevoflurane improves myocardial ischaemic tolerance in a closed-chest porcine model.
Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Animals; Disease Models, Animal; Female; Methyl Ethe | 2008 |
[Effect of sevoflurane postconditioning on spinal cord ischemia reperfusion injury via the release of oxygen free radicals in rabbits].
Topics: Animals; Disease Models, Animal; Female; Methyl Ethers; Platelet Aggregation Inhibitors; Rabbits; Re | 2008 |
The pro-nociceptive effects of remifentanil or surgical injury in mice are associated with a decrease in delta-opioid receptor mRNA levels: Prevention of the nociceptive response by on-site delivery of enkephalins.
Topics: Analgesics; Animals; Disease Models, Animal; Disulfides; Down-Regulation; Enkephalins; Ganglia, Spin | 2009 |
Does the choice of the halogenated anesthetic influence renal function during hemorrhagic shock and resuscitation?
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Cardiac Output; Creatinine; Disease Models, Animal | 2009 |
Effects of sevoflurane on carrageenan- and fentanyl-induced pain hypersensitivity in Sprague-Dawley rats.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Carrageenan; Disease Models, Animal; Dose-Resp | 2009 |
Hypertrophied hearts: what of sevoflurane cardioprotection?
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Female; Hypertrophy, Left Ventricular; Met | 2009 |
Sevoflurane postconditioning converts persistent ventricular fibrillation into regular rhythm.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Hemodynamics; Ischemic Preconditioning, My | 2009 |
The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Anesthetics, Inhalat | 2009 |
[Effects of sevoflurane postconditioning on renal ischemia-reperfusion injury: experiment with rats].
Topics: Animals; Disease Models, Animal; Kidney Diseases; Male; Methyl Ethers; Rats; Rats, Sprague-Dawley; R | 2009 |
Sevoflurane preconditioning induces rapid ischemic tolerance against spinal cord ischemia/reperfusion through activation of extracellular signal-regulated kinase in rabbits.
Topics: Anesthetics, Inhalation; Animals; Aorta, Abdominal; Apoptosis; Butadienes; Cell Survival; Constricti | 2009 |
The acute hypoxic ventilatory response under halothane, isoflurane, and sevoflurane anaesthesia in rats.
Topics: Anesthetics, Inhalation; Animals; Carbon Dioxide; Disease Models, Animal; Dose-Response Relationship | 2010 |
[Protective effects of sevoflurane preconditioning on cerebral ischemia-reperfusion injury in rats].
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Disease Models, Animal; Ischemic Preconditioning; Male; M | 2009 |
Bolus oral or continuous intestinal amino acids reduce hypothermia during anesthesia in rats.
Topics: Administration, Oral; Amino Acids; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intrav | 2010 |
The effect of amino acid infusion on anesthesia-induced hypothermia in muscle atrophy model rats.
Topics: Amino Acids; Analysis of Variance; Anesthesia, General; Anesthetics, Inhalation; Animals; Blood Gluc | 2010 |
Effects of methylene blue and volatile anesthetics on survival in a murine hemorrhage resuscitation model.
Topics: Analysis of Variance; Animals; Chi-Square Distribution; Disease Models, Animal; Fluid Therapy; Halot | 2010 |
State-specific effects of sevoflurane anesthesia on sleep homeostasis: selective recovery of slow wave but not rapid eye movement sleep.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Disease Models, Animal; Electroencephalograp | 2011 |
A dog model to study ovary, ovarian ligament and visceral pain.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Disease Models, Animal; Dogs; Female; Lapa | 2011 |
Synergic bronchodilator effects of a phosphodiesterase 3 inhibitor olprinone with a volatile anaesthetic sevoflurane in ovalbumin-sensitised guinea pigs.
Topics: Acetylcholine; Airway Resistance; Anesthetics, Inhalation; Animals; Bronchial Hyperreactivity; Bronc | 2011 |
Sevoflurane preconditioning protects blood-brain-barrier against brain ischemia.
Topics: Anesthetics, Inhalation; Animals; Blood-Brain Barrier; Blotting, Western; Brain Ischemia; Disease Mo | 2011 |
Delayed neuroprotection induced by sevoflurane via opening mitochondrial ATP-sensitive potassium channels and p38 MAPK phosphorylation.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Brain Infarction; Cell Count; Decanoic Acids; | 2012 |
Hypothermia and anesthetic postconditioning influence the expression and activity of small intestinal proteins possibly involved in ischemia/reperfusion-mediated events following cardiopulmonary resuscitation.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Biomarkers; Blotting, Western; Cardiopulmo | 2012 |
Pharmacological postconditioning with sevoflurane after cardiopulmonary resuscitation reduces myocardial dysfunction.
Topics: Animals; Cardiopulmonary Resuscitation; Cardiotonic Agents; Disease Models, Animal; Heart Arrest; Me | 2011 |
The involvement of adenosine triphosphate-sensitive potassium channels in the different effects of sevoflurane and propofol on glucose metabolism in fed rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Glucose; Blood Pressure; Disease M | 2012 |
Determination of minimum alveolar concentration for isoflurane and sevoflurane in a rodent model of human metabolic syndrome.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Behavior, Animal; Disease Models, Anim | 2012 |
Thrombotic stroke in the anesthetized monkey (Macaca mulatta): characterization by MRI--a pilot study.
Topics: Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Atracurium; Craniotomy; Dif | 2012 |
Volatile anesthetic preconditioning attenuated sepsis induced lung inflammation.
Topics: Anesthetics, Inhalation; Animals; Cecum; Disease Models, Animal; Intercellular Adhesion Molecule-1; | 2012 |
Diabetes abolishes the cardioprotection induced by sevoflurane postconditioning in the rat heart in vivo: roles of glycogen synthase kinase-3β and its upstream pathways.
Topics: Anesthetics, Inhalation; Animals; Cardiotonic Agents; Diabetes Mellitus, Experimental; Disease Model | 2012 |
Sevoflurane postconditioning involves an up-regulation of HIF-1α and HO-1 expression via PI3K/Akt pathway in a rat model of focal cerebral ischemia.
Topics: Androstadienes; Animals; Brain Ischemia; Disease Models, Animal; Gene Expression Regulation; Heme Ox | 2012 |
Ischemia-reperfusion-induced unmeasured anion generation and glycocalyx shedding: sevoflurane versus propofol anesthesia.
Topics: Acid-Base Equilibrium; Anesthetics; Animals; Capillary Permeability; Disease Models, Animal; Endothe | 2012 |
Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury.
Topics: Acute Lung Injury; Analysis of Variance; Anesthesia; Anesthetics, Dissociative; Anesthetics, General | 2012 |
Sevoflurane preconditioning improves mitochondrial function and long-term neurologic sequelae after transient cerebral ischemia: role of mitochondrial permeability transition.
Topics: Animals; Brain; Disease Models, Animal; Ischemic Attack, Transient; Ischemic Preconditioning; Methyl | 2012 |
Effect of Sevoflurane postconditioning on gene expression in brain tissue of the middle cerebral artery occlusion rat model.
Topics: Animals; bcl-2-Associated X Protein; Brain; Brain Ischemia; Caspase 3; Catalase; Disease Models, Ani | 2012 |
[Sevoflurane preconditioning produces delayed cardioprotection effect through up-regulation of inducible nitric oxide synthase in rats].
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Male | 2012 |
Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Behavior, Animal; Blotting, Western; | 2013 |
Age and anesthetic effects on murine electrocardiography.
Topics: Aging; Anesthetics, Combined; Anesthetics, Inhalation; Animals; Disease Models, Animal; Electrocardi | 2003 |
Desflurane results in higher cerebral blood flow than sevoflurane or isoflurane at hypocapnia in pigs.
Topics: Anesthetics, Inhalation; Animals; Blood Flow Velocity; Blood Pressure; Cerebrovascular Circulation; | 2004 |
Sevoflurane-induced preconditioning protects against cerebral ischemic neuronal damage in rats.
Topics: Action Potentials; Anesthetics, Inhalation; Animals; Brain Ischemia; Cell Death; Disease Models, Ani | 2005 |
Opposing effects of isoflurane and sevoflurane on neurogenic pulmonary edema development in an animal model.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Isoflurane; Male; Methyl Et | 2005 |
Effects of sevoflurane and desflurane in CA1 after incomplete cerebral ischemia in rats.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Biopsy, Needle; Brain Ischemia; Cerebrovascu | 2005 |
Sevoflurane alters right ventricular performance but not pulmonary vascular resistance in acutely instrumented anesthetized pigs.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Pressure; Disease Models, Animal; Do | 2006 |
Quantitative analysis of influence of sevoflurane on the reactivity of microglial cells in the course of the experimental model of intracerebral haemorrhage.
Topics: Anesthetics, Inhalation; Animals; Cerebral Hemorrhage; Cerebrovascular Circulation; Disease Models, | 2006 |
Laboratory investigation: effects of propofol on the systemic inflammatory response during aortic surgery.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Aorta; Creatinine; Disease Models, Anima | 2006 |
Lung mechanics and histology during sevoflurane anesthesia in a model of chronic allergic asthma.
Topics: Anesthetics, Inhalation; Animals; Asthma; Disease Models, Animal; Hypersensitivity; Lung; Methyl Eth | 2007 |
Sevoflurane affects neurogenesis after forebrain ischemia in rats.
Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Cell Proliferation; Dentate Gyrus; Disease Models, | 2007 |
Pre-occlusion ischaemia, not sevoflurane, successfully preconditions the myocardium against further damage in porcine in vivo hearts.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Cardiotonic Agents; Coronary Circulation; Disease | 2007 |
Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics.
Topics: Acetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Anesthetics, Inha | 2007 |
Postconditioning with a volatile anaesthetic in alveolar epithelial cells in vitro.
Topics: Acute Disease; Anesthetics; Animals; Carbon Dioxide; Disease Models, Animal; Endotoxins; Epithelial | 2008 |
Sevoflurane enhances ethanol-induced cardiac preconditioning through modulation of protein kinase C, mitochondrial KATP channels, and nitric oxide synthase, in guinea pig hearts.
Topics: Anesthetics, Inhalation; Animals; Benzophenanthridines; Blotting, Western; Cardiotonic Agents; Decan | 2008 |
Hepatic energy metabolism and the differential protective effects of sevoflurane and isoflurane anesthesia in a rat hepatic ischemia-reperfusion injury model.
Topics: Adenosine Triphosphate; Alanine Transaminase; Anesthetics, Inhalation; Animals; Aspartate Aminotrans | 2008 |
Lung injury following thoracic aortic occlusion: comparison of sevoflurane and propofol anaesthesia.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Aorta, Thoracic; Arterial Oc | 2008 |
Additive cardioprotection by ethanol and sevoflurane: are sarcolemmal K ATP channels also involved?
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Enzyme Activation; Ethanol; KATP Channels; Meth | 2008 |