sevoflurane has been researched along with Critical Illness in 16 studies
Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol infusion syndrome is a rare condition that mainly affects critically ill patients who receive high doses of this hypnotic for a long time." | 7.96 | Propofol infusion syndrome; are high doses always required? ( Boliart de San Félix, Y; Fernández Morales, M; Sánchez Royo, E; Subirà González, A; Vila Lolo, C, 2020) |
| "Propofol infusion syndrome is a rare condition that mainly affects critically ill patients who receive high doses of this hypnotic for a long time." | 3.96 | Propofol infusion syndrome; are high doses always required? ( Boliart de San Félix, Y; Fernández Morales, M; Sánchez Royo, E; Subirà González, A; Vila Lolo, C, 2020) |
| " However, evidence for long-term use remains low." | 3.30 | Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients - A randomized controlled trial. ( Christel, A; Kellner, P; Michel, P; Schittek, GA; Soukup, J; Wagner, NM, 2023) |
| "The sevoflurane was administered with an expired fraction target of 2% during short-term procedural sedation." | 1.48 | Sevoflurane for procedural sedation in critically ill patients: A pharmacokinetic comparative study between burn and non-burn patients. ( Bazin, JE; Biboulet, C; Bourdeaux, D; Constantin, JM; Houze, P; Launay, JM; Legrand, M; Lenoire, A; Mebazaa, A; Perbet, S; Pereira, B; Plaud, B; Sadoune, M; Sautou, V, 2018) |
| "Sevoflurane was administered via the anesthetic conserving device (AnaConDa) connected to a Servo-I ventilator (Maquet, Solna, Sweden)." | 1.48 | An Exploratory Study of Sevoflurane as an Alternative for Difficult Sedation in Critically Ill Children. ( García, M; Llorente, AM; López-Herce, J; Mencía, S; Ordóñez, O; Palacios, A; Toledo, B, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 7 (43.75) | 2.80 |
| Authors | Studies |
|---|---|
| Soukup, J | 4 |
| Michel, P | 1 |
| Christel, A | 1 |
| Schittek, GA | 1 |
| Wagner, NM | 2 |
| Kellner, P | 3 |
| Honore, PM | 1 |
| Bousbiat, I | 1 |
| Perriens, E | 1 |
| Blackman, S | 1 |
| Subirà González, A | 1 |
| Fernández Morales, M | 1 |
| Sánchez Royo, E | 1 |
| Boliart de San Félix, Y | 1 |
| Vila Lolo, C | 1 |
| Blanchard, F | 1 |
| Perbet, S | 3 |
| James, A | 1 |
| Verdonk, F | 1 |
| Godet, T | 1 |
| Bazin, JE | 3 |
| Pereira, B | 3 |
| Lambert, C | 1 |
| Constantin, JM | 3 |
| Butragueño Laiseca, L | 1 |
| Murciano, M | 1 |
| López-Herce, J | 2 |
| Mencía, S | 2 |
| Georgevici, AI | 1 |
| Kyprianou, T | 1 |
| Herzog-Niescery, J | 1 |
| Procopiuc, L | 1 |
| Loganathan, S | 1 |
| Weber, TP | 1 |
| Bellgardt, M | 1 |
| Bourdeaux, D | 1 |
| Lenoire, A | 1 |
| Biboulet, C | 1 |
| Sadoune, M | 1 |
| Plaud, B | 1 |
| Launay, JM | 1 |
| Sautou, V | 1 |
| Mebazaa, A | 1 |
| Houze, P | 1 |
| Legrand, M | 1 |
| Palacios, A | 1 |
| García, M | 1 |
| Llorente, AM | 1 |
| Ordóñez, O | 1 |
| Toledo, B | 1 |
| de Graaff, JC | 1 |
| Houmes, RJ | 1 |
| Tibboel, D | 1 |
| Jamal, JA | 1 |
| Roger, C | 1 |
| Roberts, JA | 1 |
| Chabanne, R | 1 |
| Futier, E | 1 |
| Ben Said, NA | 1 |
| Jaber, S | 1 |
| Migliari, M | 1 |
| Bellani, G | 1 |
| Rona, R | 1 |
| Isgrò, S | 1 |
| Vergnano, B | 1 |
| Mauri, T | 1 |
| Patroniti, N | 1 |
| Pesenti, A | 1 |
| Foti, G | 1 |
| Schärff, K | 1 |
| Kubosch, K | 1 |
| Pohl, C | 1 |
| Bomplitz, M | 1 |
| Kompardt, J | 1 |
| Selle, A | 1 |
| Wienke, A | 1 |
| Steighardt, J | 1 |
| Moore, EW | 1 |
| Davies, MW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Depth of Long Term ICU Sedation Under 0,5 MAC Isoflurane, Sevoflurane or Desflurane Using MIRUS, an Automated Delivery System for Volatile Anaesthetics[NCT03860129] | 30 participants (Actual) | Interventional | 2014-12-10 | Completed | |||
| A Pharmacokinetic Study of Sevoflurane Inhalation in Burn ICU Patients[NCT02048683] | Phase 2 | 24 participants (Actual) | Interventional | 2013-12-31 | Completed | ||
| Evaluation of Mirus™ for Sedation in Resuscitation[NCT02889055] | 9 participants (Actual) | Observational | 2016-01-17 | Terminated (stopped due to Safety profile was not satisfying with sevolflurane) | |||
| AnaConDa-therapy in COVID-19 Patients[NCT05586126] | 42 participants (Actual) | Observational | 2020-10-01 | Terminated (stopped due to Concerns about possible association between drug and increased ICU mortality) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for sevoflurane and Critical Illness
| Article | Year |
|---|---|
State of the art: sedation concepts with volatile anesthetics in critically Ill patients.
Topics: Anesthetics, Inhalation; Clinical Trials as Topic; Critical Illness; Drug Delivery Systems; Humans; | 2009 |
7 trials available for sevoflurane and Critical Illness
| Article | Year |
|---|---|
Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients - A randomized controlled trial.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Pro | 2023 |
Letter to the Editor: "Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients - A randomized controlled trial".
Topics: Anesthesia; Anesthetics, Inhalation; Conscious Sedation; Critical Illness; Humans; Hypnotics and Sed | 2023 |
Author's response: Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients - A randomized controlled trial.
Topics: Conscious Sedation; Critical Illness; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofo | 2023 |
Negative drift of sedation depth in critically ill patients receiving constant minimum alveolar concentration of isoflurane, sevoflurane, or desflurane: a randomized controlled trial.
Topics: Aged; Critical Illness; Desflurane; Drug Monitoring; Electroencephalography; Female; Humans; Hypnoti | 2021 |
Impact of the anesthetic conserving device on respiratory parameters and work of breathing in critically ill patients under light sedation with sevoflurane.
Topics: Adult; Aged; Critical Illness; Female; Humans; Hypnotics and Sedatives; Male; Methyl Ethers; Middle | 2014 |
Short-term evaluation of sedation with sevoflurane administered by the anesthetic conserving device in critically ill patients.
Topics: Administration, Inhalation; Aged; Anesthesiology; Anesthetics, Inhalation; Critical Illness; Cross-O | 2009 |
Efficiency and safety of inhalative sedation with sevoflurane in comparison to an intravenous sedation concept with propofol in intensive care patients: study protocol for a randomized controlled trial.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Cost-Benefit Analysis | 2012 |
8 other studies available for sevoflurane and Critical Illness
| Article | Year |
|---|---|
Propofol infusion syndrome; are high doses always required?
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Chemical | 2020 |
Minimal alveolar concentration for deep sedation (MAC-DS) in intensive care unit patients sedated with sevoflurane: A physiological study.
Topics: Aged; Anesthetics, Inhalation; Consciousness Monitors; Critical Care; Critical Illness; Deep Sedatio | 2020 |
Inhaled sedation with sevoflurane in critically ill children during extracorporeal membrane oxygenation.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Critical Illness; Extracorporeal Membrane Ox | 2021 |
Sevoflurane for procedural sedation in critically ill patients: A pharmacokinetic comparative study between burn and non-burn patients.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Burns; Conscious Sedat | 2018 |
An Exploratory Study of Sevoflurane as an Alternative for Difficult Sedation in Critically Ill Children.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Critical Illness; Dose-Response Relationship, D | 2018 |
Navigating Between Scylla and Charybdis; Sevoflurane for Difficult Sedation at the PICU.
Topics: Anesthesia; Child; Critical Illness; Humans; Intensive Care Units, Pediatric; Sevoflurane | 2018 |
Understanding the impact of pathophysiological alterations during critical illness on drug pharmacokinetics.
Topics: Burns; Critical Illness; Humans; Sevoflurane | 2018 |
Inhalational versus intravenous induction. A survey of emergency anaesthetic practice in the United Kingdom.
Topics: Acute Disease; Adolescent; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhal | 2000 |