Page last updated: 2024-11-04

sevoflurane and Coronary Heart Disease

sevoflurane has been researched along with Coronary Heart Disease in 12 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Research Excerpts

ExcerptRelevanceReference
"It is skeptical about cardioprotective property of sevoflurane in patients undergoing noncardiac surgery, especially in the elderly patients with coronary heart disease."9.24Randomized comparison of sevoflurane versus propofol-remifentanil on the cardioprotective effects in elderly patients with coronary heart disease. ( Feng, X; Lin, W; Shen, S; Sun, J; Wang, H; Zhang, Y, 2017)
"In patients without significant cardiovascular disease, the hemodynamic effects of sevoflurane and isoflurane are similar; however, the hemodynamic effects of sevoflurane in patients with hypertension and ischemic heart disease are unknown."9.08The hemodynamic and renal effects of sevoflurane and isoflurane in patients with coronary artery disease and chronic hypertension. Sevoflurane Ischemia Study Group. ( Ebert, T; Kharasch, ED; Muzi, M; Rooke, GA, 1996)
"Sevoflurane is associated with less tachycardia and coronary vasodilation than isoflurane and thus might be associated with less myocardial ischemia."9.08Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group. ( Ebert, TJ; Kharasch, ED; Muzi, M; Rooke, GA; Shroff, A, 1997)
"It is skeptical about cardioprotective property of sevoflurane in patients undergoing noncardiac surgery, especially in the elderly patients with coronary heart disease."5.24Randomized comparison of sevoflurane versus propofol-remifentanil on the cardioprotective effects in elderly patients with coronary heart disease. ( Feng, X; Lin, W; Shen, S; Sun, J; Wang, H; Zhang, Y, 2017)
"In patients without significant cardiovascular disease, the hemodynamic effects of sevoflurane and isoflurane are similar; however, the hemodynamic effects of sevoflurane in patients with hypertension and ischemic heart disease are unknown."5.08The hemodynamic and renal effects of sevoflurane and isoflurane in patients with coronary artery disease and chronic hypertension. Sevoflurane Ischemia Study Group. ( Ebert, T; Kharasch, ED; Muzi, M; Rooke, GA, 1996)
"Sevoflurane is associated with less tachycardia and coronary vasodilation than isoflurane and thus might be associated with less myocardial ischemia."5.08Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group. ( Ebert, TJ; Kharasch, ED; Muzi, M; Rooke, GA; Shroff, A, 1997)
"Treatment with sevoflurane before coronary occlusion seem effective in reducing functional myocardial impairment due to ischemia."2.71[Cardiac protection is a clinical evidence]. ( Baldassarri, R; Cariello, C; Doroni, L; Guarracino, F; Vullo, C, 2004)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (66.67)18.2507
2000's3 (25.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, Y1
Lin, W1
Shen, S1
Wang, H1
Feng, X1
Sun, J1
Guarracino, F1
Doroni, L1
Cariello, C1
Baldassarri, R1
Vullo, C1
Lorsomradee, S2
Cromheecke, S1
De Hert, SG1
Venkatesh, BG1
Mehta, Y1
Kumar, A1
Trehan, N1
Watanabe, S1
Hamada, N1
Tsuda, H1
Muteki, T1
Kersten, JR1
Brayer, AP1
Pagel, PS1
Tessmer, JP1
Warltier, DC1
Rooke, GA2
Ebert, T1
Muzi, M2
Kharasch, ED2
Ebert, TJ1
Shroff, A1
Preckel, B1
Schlack, W1
Comfère, T1
Obal, D1
Barthel, H1
Thämer, V1
Wang, JY1
Winship, SM1
Thomas, SD1
Gin, T1
Russell, GN1
Kimura, H1
Abe, T1
Kitahata, H2
Iseki, A1
Kawahito, S1
Saito, T1
Goh, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective Randomised Controled Trial: Comparison of Volatile Anaesthetics Sevoflurane vs. Isoflurane for Low-Flow General Anaesthesia for Abdominal Surgery[NCT00521612]82 participants (Actual)Interventional2007-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for sevoflurane and Coronary Heart Disease

ArticleYear
Randomized comparison of sevoflurane versus propofol-remifentanil on the cardioprotective effects in elderly patients with coronary heart disease.
    BMC anesthesiology, 2017, Aug-11, Volume: 17, Issue:1

    Topics: Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Cardiac Output; Cardioto

2017
[Cardiac protection is a clinical evidence].
    Minerva anestesiologica, 2004, Volume: 70, Issue:5

    Topics: Aged; Anesthetics, Inhalation; Coronary Disease; Female; Humans; Male; Methyl Ethers; Myocardial Isc

2004
Effects of sevoflurane on biomechanical markers of hepatic and renal dysfunction after coronary artery surgery.
    Journal of cardiothoracic and vascular anesthesia, 2006, Volume: 20, Issue:5

    Topics: Administration, Inhalation; Aged; Alanine Transaminase; Anesthesia, General; Anesthetics, Inhalation

2006
The hemodynamic and renal effects of sevoflurane and isoflurane in patients with coronary artery disease and chronic hypertension. Sevoflurane Ischemia Study Group.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Pressure; Blood Urea Nitrogen; C

1996
Myocardial ischemia and adverse cardiac outcomes in cardiac patients undergoing noncardiac surgery with sevoflurane and isoflurane. Sevoflurane Ischemia Study Group.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Coronary Disease; Ethers; Female; Heart Dis

1997
Induction of anaesthesia in patients with coronary artery disease: a comparison between sevoflurane-remifentanil and fentanyl-etomidate.
    Anaesthesia and intensive care, 1999, Volume: 27, Issue:4

    Topics: Adrenergic beta-Antagonists; Analgesics, Opioid; Anesthetics, Combined; Anesthetics, Inhalation; Ane

1999

Other Studies

6 other studies available for sevoflurane and Coronary Heart Disease

ArticleYear
Comparison of sevoflurane and isoflurane in OPCAB surgery.
    Annals of cardiac anaesthesia, 2007, Volume: 10, Issue:1

    Topics: Aged; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure;

2007
[The effects of sevoflurane on the coronary circulation in the instrumented dog with or without coronary stenosis].
    Masui. The Japanese journal of anesthesiology, 1995, Volume: 44, Issue:8

    Topics: Anesthetics; Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Dogs; Dose-Response Re

1995
Perfusion of ischemic myocardium during anesthesia with sevoflurane.
    Anesthesiology, 1994, Volume: 81, Issue:4

    Topics: Anesthesia, Endotracheal; Anesthetics; Animals; Blood Pressure; Coronary Disease; Dogs; Dose-Respons

1994
Effects of enflurane, isoflurane, sevoflurane and desflurane on reperfusion injury after regional myocardial ischaemia in the rabbit heart in vivo.
    British journal of anaesthesia, 1998, Volume: 81, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Coronary Disease; Desflurane; Enflurane; Hemodynamics; Isoflurane;

1998
[Effects of sevoflurane on regional myocardial oxygen balance in the canine heart with coronary artery stenosis].
    Masui. The Japanese journal of anesthesiology, 1992, Volume: 41, Issue:9

    Topics: Anesthesia, Inhalation; Anesthetics; Animals; Coronary Circulation; Coronary Disease; Dogs; Ethers;

1992
[Effects of sevoflurane, isoflurane, and halothane on regional myocardial blood flow in the ischemic canine heart].
    Masui. The Japanese journal of anesthesiology, 1991, Volume: 40, Issue:2

    Topics: Anesthetics; Animals; Coronary Circulation; Coronary Disease; Dogs; Ethers; Halothane; Isoflurane; M

1991