Page last updated: 2024-11-04

sevoflurane and Consciousness, Loss of

sevoflurane has been researched along with Consciousness, Loss of in 36 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Research Excerpts

ExcerptRelevanceReference
" Anesthesia was induced and maintained with sevoflurane in an oxygen/air mixture."7.74Effects of pain stimulation on bispectral index, heart rate and blood pressure at different minimal alveolar concentration values of sevoflurane. ( Axelsson, K; Dahlqvist, A; Sandin, M; Thörn, SE; Wattwil, L; Wattwil, M, 2008)
"Sevoflurane was initiated in both groups at 8% for anesthesia induction until loss of consciousness was achieved, at which point it was discontinued."6.80Effect of the Addition of Ketamine to Sevoflurane Anesthesia on Seizure Duration in Electroconvulsive Therapy. ( Çolak, C; Cumurcu, B; Durmus, M; Erdil, F; Ozgul, U, 2015)
" Anesthesia was induced and maintained with sevoflurane in an oxygen/air mixture."3.74Effects of pain stimulation on bispectral index, heart rate and blood pressure at different minimal alveolar concentration values of sevoflurane. ( Axelsson, K; Dahlqvist, A; Sandin, M; Thörn, SE; Wattwil, L; Wattwil, M, 2008)
"Sevoflurane was initiated in both groups at 8% for anesthesia induction until loss of consciousness was achieved, at which point it was discontinued."2.80Effect of the Addition of Ketamine to Sevoflurane Anesthesia on Seizure Duration in Electroconvulsive Therapy. ( Çolak, C; Cumurcu, B; Durmus, M; Erdil, F; Ozgul, U, 2015)
"NT monitoring can be used to effectively predict the recovery of consciousness in patients undergoing abdominal surgery and facilitates a significant reduction of the recovery time and sufentanil dosage during a sevoflurane-sufentanil anesthesia."2.75[Narcotrend index monitoring can predict the recovery of consciousness in patients undergoing abdominal surgery]. ( Gu, MN; Sun, CJ; Xu, JS, 2010)
"Gender affects the dosing requirements for, and response to, many drugs used in anesthetic practice."2.71The influence of gender on loss of consciousness with sevoflurane or propofol. ( Johansen, JW; Kodaka, M; Sebel, PS, 2005)
"Anesthetic-induced loss of consciousness (LOC) has been studied using functional connectivity (FC) and functional network analysis (FNA), manifested as fragmentation of the whole-brain functional network."1.91Recovery of Brain Network Integration and Segregation During the Loss and Recovery of Consciousness Induced by Sevoflurane. ( Chen, X; Dong, K; Liu, J; Wang, G; Wei, Q; Zhang, D; Zhang, L, 2023)
"These results suggest that loss of consciousness is accompanied by an augmentation of temporal persistence in neuronal oscillation amplitude, which may reflect an increase in regularity and a decrease in network repertoire compared to the brain's activity during resting-state consciousness."1.48Long-range temporal correlations in the brain distinguish conscious wakefulness from induced unconsciousness. ( Blain-Moraes, S; Combrisson, E; Dehgan, A; Jerbi, K; Lajnef, T; Mashour, GA; Rainville, P; Thiery, T, 2018)
"Sevoflurane-induced unconsciousness is associated with both globally reduced BOLD signal amplitudes and selectively reduced functional connectivity within cortical networks associated with consciousness (default mode network) and orienting to salient external stimuli (ventral attention network)."1.42Resting-state Functional Magnetic Resonance Imaging Correlates of Sevoflurane-induced Unconsciousness. ( Avidan, MS; Larson-Prior, L; Mitra, A; Palanca, BJ; Raichle, ME; Snyder, AZ, 2015)
"Immediately after loss of consciousness, assisted tidal volume ventilation with a fixed 3."1.35Arterial blood concentration of sevoflurane during single-breath induction and tracheal intubation in gynecologic patients. ( Chang, CC; Ho, ST; Li, CY; Lin, TC; Lu, CC, 2008)
"Propofol concentration was determined using high-performance liquid chromatography."1.33The influence of sevoflurane on the bispectral index, regional cerebral oxygen saturation, and propofol concentration during propofol/N2O anesthesia. ( Goto, F; Hagiwara, R; Kanemaru, Y; Nishikawa, K, 2006)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.56)18.2507
2000's9 (25.00)29.6817
2010's15 (41.67)24.3611
2020's10 (27.78)2.80

Authors

AuthorsStudies
Dong, K4
Zhang, D4
Wei, Q4
Wang, G4
Huang, F2
Chen, X4
Muhammad, KG2
Sun, Y1
Liu, J4
Low, SS1
Zhang, L2
Zhou, F1
Wang, D1
Li, H1
Wang, S1
Zhang, X1
Li, A1
Tong, T1
Zhong, H1
Yang, Q1
Dong, H1
Adam, E1
Kwon, O1
Montejo, KA1
Brown, EN2
Pappas, I1
Cornelissen, L1
Menon, DK1
Berde, CB1
Stamatakis, EA1
Conti, A1
Akeju, O1
Duggento, A1
Chamadia, S1
Barbieri, R1
Toschi, N1
Reitz, SL1
Wasilczuk, AZ1
Beh, GH1
Proekt, A1
Kelz, MB1
Bao, WW1
Xu, W1
Pan, GJ1
Wang, TX1
Han, Y1
Qu, WM1
Li, WX1
Huang, ZL1
Abel, JH1
Badgeley, MA1
Meschede-Krasa, B1
Schamberg, G1
Garwood, IC1
Lecamwasam, K1
Chakravarty, S1
Zhou, DW1
Keating, M1
Purdon, PL1
Palanca, BJA1
Avidan, MS2
Mashour, GA5
Zhang, J2
Huang, Z1
Chen, Y1
Ghinda, D1
Nikolova, Y1
Wu, J1
Xu, J1
Bai, W1
Mao, Y1
Yang, Z1
Duncan, N1
Qin, P1
Wang, H1
Chen, B1
Weng, X1
Northoff, G1
Thiery, T1
Lajnef, T1
Combrisson, E1
Dehgan, A1
Rainville, P1
Blain-Moraes, S2
Jerbi, K1
Kim, H1
Moon, JY1
Lee, U1
Finley, J1
Golkowski, D2
Larroque, SK1
Vanhaudenhuyse, A1
Plenevaux, A1
Boly, M1
Di Perri, C1
Ranft, A2
Schneider, G3
Laureys, S1
Jordan, D3
Bonhomme, V1
Ilg, R2
Tsai, FF1
Fan, SZ1
Cheng, HL1
Yeh, JR1
Lin, YT1
Wu, HT1
Tsao, J1
Yien, HW1
Hseu, SS1
Tarnal, V1
Vanini, G1
Alexander, A1
Rosen, D1
Shortal, B1
Janke, E1
Erdil, F1
Ozgul, U1
Çolak, C1
Cumurcu, B1
Durmus, M1
Palanca, BJ1
Mitra, A1
Larson-Prior, L1
Snyder, AZ1
Raichle, ME1
Kiel, T1
Riedl, V1
Kohl, P1
Rohrer, G1
Pientka, J1
Berger, S1
Thul, A1
Maurer, M1
Preibisch, C1
Zimmer, C1
Kochs, EF3
Lin, TC1
Lu, CC1
Li, CY1
Chang, CC1
Ho, ST1
Sun, CJ1
Gu, MN1
Xu, JS1
Kaskinoro, K1
Maksimow, A1
Långsjö, J1
Aantaa, R1
Jääskeläinen, S1
Kaisti, K1
Särkelä, M1
Scheinin, H1
Horn, B1
Kreuzer, M1
Ningler, M1
Kodaka, M1
Johansen, JW1
Sebel, PS1
Nishikawa, K1
Kanemaru, Y1
Hagiwara, R1
Goto, F1
Stockmanns, G1
Sandin, M1
Thörn, SE1
Dahlqvist, A1
Wattwil, L1
Axelsson, K1
Wattwil, M1
Yurino, M1
Kimura, H1
Vakkuri, A1
Yli-Hankala, A1
Korttila, K1
Lindgren, L1
Litvan, H2
Jensen, EW2
Maestre, ML1
Galán, J1
Campos, JM2
Fernández, JA1
Caminal, P2
Villar Landeira, JM2
Revuelta, M1
Henneberg, SW1
Paniagua, P1
Martínez, P1
Nishiyama, T1
Matsukawa, T1
Yokoyama, T1
Hanaoka, K1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
To Record and Analyze the Physiological Data From Anesthetic Monitoring Instruments Regarding Cardiovascular, Neurological System, and Surgical Stress for Patients Undergoing Laparoscopic Cholecystectomy in a Stepwise Approach.[NCT03691103]40 participants (Anticipated)Observational2018-09-30Not yet recruiting
Study on the Influencing Factors of Electroencephalogram Parameters Under Anesthesia[NCT04760028]Phase 480 participants (Actual)Interventional2021-03-01Completed
Effect of S-ketamine on Depressed Patients Undergoing Electroconvulsive Therapy-a Randomized, Double-blind, Controlled Clinical Study[NCT04399070]150 participants (Anticipated)Interventional2020-08-01Not yet recruiting
Influence of Gender on Interaction of Propofol and Dexmedetomidine[NCT02853864]Phase 4120 participants (Actual)Interventional2016-08-31Completed
The Influence of Age on Dexmedetomidine Pharmacodynamic in Lower Extremity Surgery[NCT02099253]Phase 482 participants (Actual)Interventional2014-03-31Completed
Low Dose Fentanyl/Midazolam Improves Sevoflurane Induction in Adults[NCT00723164]80 participants (Actual)Interventional2005-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for sevoflurane and Consciousness, Loss of

ArticleYear
Human neural correlates of sevoflurane-induced unconsciousness.
    British journal of anaesthesia, 2017, Oct-01, Volume: 119, Issue:4

    Topics: Anesthetics, Inhalation; Brain; Electroencephalography; Humans; Magnetic Resonance Imaging; Sevoflur

2017

Trials

9 trials available for sevoflurane and Consciousness, Loss of

ArticleYear
Effect of the Addition of Ketamine to Sevoflurane Anesthesia on Seizure Duration in Electroconvulsive Therapy.
    The journal of ECT, 2015, Volume: 31, Issue:3

    Topics: Adult; Anesthesia; Anesthesia Recovery Period; Anesthetics, Dissociative; Anesthetics, Inhalation; A

2015
[Narcotrend index monitoring can predict the recovery of consciousness in patients undergoing abdominal surgery].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2010, Volume: 30, Issue:6

    Topics: Abdomen; Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inha

2010
Narcotrend does not adequately detect the transition between awareness and unconsciousness in surgical patients.
    Anesthesiology, 2004, Volume: 101, Issue:5

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Awareness; Electroenc

2004
The influence of gender on loss of consciousness with sevoflurane or propofol.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:2

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Arousal; Cross-Over S

2005
The influence of gender on loss of consciousness with sevoflurane or propofol.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:2

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Arousal; Cross-Over S

2005
The influence of gender on loss of consciousness with sevoflurane or propofol.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:2

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Arousal; Cross-Over S

2005
The influence of gender on loss of consciousness with sevoflurane or propofol.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:2

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Arousal; Cross-Over S

2005
Median frequency revisited: an approach to improve a classic spectral electroencephalographic parameter for the separation of consciousness from unconsciousness.
    Anesthesiology, 2007, Volume: 107, Issue:3

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Consciousness; Electr

2007
Vital capacity rapid inhalation induction technique: comparison of sevoflurane and halothane.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:5 Pt 1

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics; Blood Pressure; Ethers; Fema

1993
[Comparison of an auditory evoked potentials index and a bispectral index versus clinical signs for determining the depth of anesthesia produced by propofol or sevoflurane].
    Revista espanola de anestesiologia y reanimacion, 2000, Volume: 47, Issue:10

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics,

2000
Comparison of auditory evoked potentials and the A-line ARX Index for monitoring the hypnotic level during sevoflurane and propofol induction.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:3

    Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Cardiac Surgical Procedures; Evoked P

2002
Rapid inhalation induction with 7% sevoflurane combined with intravenous midazolam.
    Journal of clinical anesthesia, 2002, Volume: 14, Issue:4

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, In

2002

Other Studies

26 other studies available for sevoflurane and Consciousness, Loss of

ArticleYear
Intrinsic phase-amplitude coupling on multiple spatial scales during the loss and recovery of consciousness.
    Computers in biology and medicine, 2022, Volume: 147

    Topics: Brain; Consciousness; Electroencephalography; Female; Humans; Male; Sevoflurane; Unconsciousness

2022
Dynamic alpha-gamma phase-amplitude coupling signatures during sevoflurane-induced loss and recovery of consciousness.
    Neuroscience research, 2022, Volume: 185

    Topics: Brain; Consciousness; Electroencephalography; Humans; Sevoflurane; Unconsciousness

2022
Recovery of Brain Network Integration and Segregation During the Loss and Recovery of Consciousness Induced by Sevoflurane.
    IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 2023, Volume: 31

    Topics: Brain; Consciousness; Electroencephalography; Humans; Sevoflurane; Unconsciousness

2023
An integrated information theory index using multichannel EEG for evaluating various states of consciousness under anesthesia.
    Computers in biology and medicine, 2023, Volume: 153

    Topics: Anesthesia, General; Anesthetics, Intravenous; Consciousness; Electroencephalography; Humans; Inform

2023
Orexinergic innervations at GABAergic neurons of the lateral habenula mediates the anesthetic potency of sevoflurane.
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:5

    Topics: Anesthesia, General; Anesthetics, Inhalation; GABAergic Neurons; Habenula; Humans; Sevoflurane; Unco

2023
Modulatory dynamics mark the transition between anesthetic states of unconsciousness.
    Proceedings of the National Academy of Sciences of the United States of America, 2023, 07-25, Volume: 120, Issue:30

    Topics: Anesthetics; Brain; Electroencephalography; Humans; Propofol; Sevoflurane; Unconsciousness

2023
δ-Oscillation Correlates of Anesthesia-induced Unconsciousness in Large-scale Brain Networks of Human Infants.
    Anesthesiology, 2019, Volume: 131, Issue:6

    Topics: Anesthetics, Inhalation; Brain; Cohort Studies; Consciousness; Delta Rhythm; Electroencephalography;

2019
Frequency dependent functional brain reorganization in anesthesia is specific to drug concentration.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2020, Volume: 2020

    Topics: Adult; Anesthesia, General; Brain; Humans; Magnetic Resonance Imaging; Male; Sevoflurane; Unconsciou

2020
Activation of Preoptic Tachykinin 1 Neurons Promotes Wakefulness over Sleep and Volatile Anesthetic-Induced Unconsciousness.
    Current biology : CB, 2021, 01-25, Volume: 31, Issue:2

    Topics: Administration, Inhalation; Anesthesia, Inhalation; Animals; Arousal; Electroencephalography; Female

2021
Nucleus accumbens neurons expressing dopamine D1 receptors modulate states of consciousness in sevoflurane anesthesia.
    Current biology : CB, 2021, 05-10, Volume: 31, Issue:9

    Topics: Anesthesia; Consciousness; Humans; Neurons; Nucleus Accumbens; Receptors, Dopamine D1; Sevoflurane;

2021
Machine learning of EEG spectra classifies unconsciousness during GABAergic anesthesia.
    PloS one, 2021, Volume: 16, Issue:5

    Topics: Anesthetics, Intravenous; Brain; Electroencephalography; Humans; Machine Learning; Male; Sevoflurane

2021
Breakdown in the temporal and spatial organization of spontaneous brain activity during general anesthesia.
    Human brain mapping, 2018, Volume: 39, Issue:5

    Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Brain; Brain Mapping; Female; Humans; Image Pr

2018
Long-range temporal correlations in the brain distinguish conscious wakefulness from induced unconsciousness.
    NeuroImage, 2018, 10-01, Volume: 179

    Topics: Anesthetics, Inhalation; Brain; Consciousness; Electroencephalography; Female; Humans; Male; Sevoflu

2018
Mechanisms of hysteresis in human brain networks during transitions of consciousness and unconsciousness: Theoretical principles and empirical evidence.
    PLoS computational biology, 2018, Volume: 14, Issue:8

    Topics: Adult; Anesthetics, General; Brain; Connectome; Consciousness; Cortical Synchronization; Electroence

2018
Cellular stress and AMPK links metformin and diverse compounds with accelerated emergence from anesthesia and potential recovery from disorders of consciousness.
    Medical hypotheses, 2019, Volume: 124

    Topics: AMP-Activated Protein Kinases; Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Brain M

2019
Changes in Whole Brain Dynamics and Connectivity Patterns during Sevoflurane- and Propofol-induced Unconsciousness Identified by Functional Magnetic Resonance Imaging.
    Anesthesiology, 2019, Volume: 130, Issue:6

    Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Brain; Female; Humans; Magnetic Resonance

2019
Multi-timescale phase-amplitude couplings in transitions of anesthetic-induced unconsciousness.
    Scientific reports, 2019, 05-24, Volume: 9, Issue:1

    Topics: Anesthetics, General; Brain; Case-Control Studies; Electroencephalography; Humans; Sevoflurane; Unco

2019
Time-varying spectral analysis revealing differential effects of sevoflurane anaesthesia: non-rhythmic-to-rhythmic ratio.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:2

    Topics: Adult; Algorithms; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Inhalation; Anesthet

2014
Neurophysiological correlates of sevoflurane-induced unconsciousness.
    Anesthesiology, 2015, Volume: 122, Issue:2

    Topics: Alpha Rhythm; Anesthetics, Inhalation; Anesthetics, Intravenous; Behavior; Electroencephalography; F

2015
Resting-state Functional Magnetic Resonance Imaging Correlates of Sevoflurane-induced Unconsciousness.
    Anesthesiology, 2015, Volume: 123, Issue:2

    Topics: Adolescent; Adult; Anesthetics, Inhalation; Brain; Female; Humans; Magnetic Resonance Imaging; Male;

2015
Neural Correlates of Sevoflurane-induced Unconsciousness Identified by Simultaneous Functional Magnetic Resonance Imaging and Electroencephalography.
    Anesthesiology, 2016, Volume: 125, Issue:5

    Topics: Adult; Anesthetics, Inhalation; Brain; Electroencephalography; Humans; Magnetic Resonance Imaging; M

2016
Arterial blood concentration of sevoflurane during single-breath induction and tracheal intubation in gynecologic patients.
    Journal of clinical anesthesia, 2008, Volume: 20, Issue:7

    Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Pressure; Female; Gynecologic Surgical

2008
Wide inter-individual variability of bispectral index and spectral entropy at loss of consciousness during increasing concentrations of dexmedetomidine, propofol, and sevoflurane.
    British journal of anaesthesia, 2011, Volume: 107, Issue:4

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intrav

2011
The influence of sevoflurane on the bispectral index, regional cerebral oxygen saturation, and propofol concentration during propofol/N2O anesthesia.
    Journal of clinical monitoring and computing, 2006, Volume: 20, Issue:6

    Topics: Adult; Aged; Anesthetics, Inhalation; Brain; Cardiac Output; Drug Interactions; Female; Humans; Meth

2006
Effects of pain stimulation on bispectral index, heart rate and blood pressure at different minimal alveolar concentration values of sevoflurane.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:3

    Topics: Adult; Anesthesia; Anesthetics, Inhalation; Blood Pressure; Dose-Response Relationship, Drug; Electr

2008
Sevoflurane requirement for laparoscopic tubal ligation: an electroencephalographic bispectral study.
    European journal of anaesthesiology, 1999, Volume: 16, Issue:5

    Topics: Adult; Anesthetics, Inhalation; Electroencephalography; Female; Humans; Laparoscopy; Methyl Ethers;

1999