Page last updated: 2024-11-04

sevoflurane and Colorectal Cancer

sevoflurane has been researched along with Colorectal Cancer in 15 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Research Excerpts

ExcerptRelevanceReference
" Local anesthetics, especially lidocaine, have been intensively studied in relation with postoperative outcome in colorectal cancer patients."9.69The Influence of Intravenous Lidocaine Infusion on Postoperative Outcome and Neutrophil-to-Lymphocyte Ratio in Colorectal Cancer Patients. A Pilot Study. ( Al Hajjar, N; Alexa, AL; Breazu, C; Ciocan, A; Ionescu, D; Sargarovschi, S; Valean, D; Zaharie, F, 2023)
" This study hypothesized that propofol-based anesthesia would have fewer harmful effects on immune cells than volatile anesthetics-based anesthesia during colorectal cancer surgery."9.51Expression Profiles of Immune Cells after Propofol or Sevoflurane Anesthesia for Colorectal Cancer Surgery: A Prospective Double-blind Randomized Trial. ( Hwang, DY; Kim, SH; Koh, SE; Oh, CS; Park, HJ; Piao, L; Sohn, KM, 2022)
"To compare the effect of propofol and sevoflurane on perioperative immunity and surgical outcomes in patients undergoing laparoscopic radical resection of colorectal cancer."9.20[The effect of propofol and sevoflurane on the perioperative immunity in patients under laparoscopic radical resection of colorectal cancer]. ( Chen, Y; Liang, M; Zhou, D; Zhu, Y, 2015)
"To evaluate the analgesic efficacy of intraoperative dexmedetomidine (DEX) for acute postoperative pain in colorectal cancer patients undergoing laparoscopic surgery."8.12Analgesic effect of dexmedetomidine in colorectal cancer patients undergoing laparoscopic surgery. ( Ahn, HJ; Chung, YJ; Lee, JE; Lee, JY; Park, HJ; Sim, WS, 2022)
"Circulating vesicles were investigated in a prospective, matched-case pilot study in two cohorts of colorectal cancer patients receiving either propofol (n = 8) or sevoflurane (n = 9), matched for tumor stage and location."7.96Propofol and Sevoflurane Differentially Impact MicroRNAs in Circulating Extracellular Vesicles during Colorectal Cancer Resection: A Pilot Study. ( Brandes, F; Buschmann, D; Chouker, A; Ganschow, P; Lindemann, A; Maerte, M; Pfaffl, MW; Reithmair, M; Schelling, G, 2020)
" Local anesthetics, especially lidocaine, have been intensively studied in relation with postoperative outcome in colorectal cancer patients."5.69The Influence of Intravenous Lidocaine Infusion on Postoperative Outcome and Neutrophil-to-Lymphocyte Ratio in Colorectal Cancer Patients. A Pilot Study. ( Al Hajjar, N; Alexa, AL; Breazu, C; Ciocan, A; Ionescu, D; Sargarovschi, S; Valean, D; Zaharie, F, 2023)
"Sevoflurane has been reported to involve in the progression in several cancers."5.62Sevoflurane inhibits the migration, invasion and induces apoptosis by regulating the expression of WNT1 via miR-637 in colorectal cancer. ( Chen, J; Duan, JA; Hu, N; Li, D; Yan, H; Yu, Y, 2021)
" This study hypothesized that propofol-based anesthesia would have fewer harmful effects on immune cells than volatile anesthetics-based anesthesia during colorectal cancer surgery."5.51Expression Profiles of Immune Cells after Propofol or Sevoflurane Anesthesia for Colorectal Cancer Surgery: A Prospective Double-blind Randomized Trial. ( Hwang, DY; Kim, SH; Koh, SE; Oh, CS; Park, HJ; Piao, L; Sohn, KM, 2022)
"However, the effects of sevoflurane on colorectal cancer (CRC) remains largely unclear."5.51Sevoflurane inhibits migration and invasion of colorectal cancer cells by regulating microRNA-34a/ADAM10 axis. ( Liu, J; Ren, LJ; Shan, SM; Sun, SQ; Wang, P, 2019)
"To compare the effect of propofol and sevoflurane on perioperative immunity and surgical outcomes in patients undergoing laparoscopic radical resection of colorectal cancer."5.20[The effect of propofol and sevoflurane on the perioperative immunity in patients under laparoscopic radical resection of colorectal cancer]. ( Chen, Y; Liang, M; Zhou, D; Zhu, Y, 2015)
" The aim of this study was to establish and compare differences in inflammatory response among colorectal cancer surgery patients receiving either total intravenous anesthesia (TIVA) with propofol and remifentanil or inhalational anesthesia (INHAL) with sevoflurane and fentanyl."5.15Inflammatory response in patients undergoing colorectal cancer surgery: the effect of two different anesthetic techniques. ( Bengtson, JP; Bengtsson, A; Kvarnström, A; Sarbinowski, R; Tylman, M, 2011)
" Anesthesia was performed with sevoflurane in 40% O2 and without the use of nitrous oxide."4.91Multidisciplinary approach and anesthetic management of a surgical cancer patient with methylene tetrahydrofolate reductase deficiency: a case report and review of the literature. ( Accardo, R; Accardo, RR; Arcamone, M; Arcamone, MM; Belli, A; Belli, AA; Caliendo, D; Caliendo, DD; Cascella, M; Cascella, MM; Cuomo, A; Cuomo, AA; De Franciscis, S; De Franciscis, SS; De Luca, E; De Luca, EE; Di Caprio, B; Di Caprio, BB; Di Sauro, F; Di Sauro, FF; Giannoni, G; Giannoni, GG; Iermano, C; Iermano, CC; Maciariello, M; Maciariello, MM; Marracino, M; Marracino, MM; Morelli, E; Morelli, EE; Russo, V; Russo, VV; Viscardi, D; Viscardi, DD, 2015)
"To evaluate the analgesic efficacy of intraoperative dexmedetomidine (DEX) for acute postoperative pain in colorectal cancer patients undergoing laparoscopic surgery."4.12Analgesic effect of dexmedetomidine in colorectal cancer patients undergoing laparoscopic surgery. ( Ahn, HJ; Chung, YJ; Lee, JE; Lee, JY; Park, HJ; Sim, WS, 2022)
"Circulating vesicles were investigated in a prospective, matched-case pilot study in two cohorts of colorectal cancer patients receiving either propofol (n = 8) or sevoflurane (n = 9), matched for tumor stage and location."3.96Propofol and Sevoflurane Differentially Impact MicroRNAs in Circulating Extracellular Vesicles during Colorectal Cancer Resection: A Pilot Study. ( Brandes, F; Buschmann, D; Chouker, A; Ganschow, P; Lindemann, A; Maerte, M; Pfaffl, MW; Reithmair, M; Schelling, G, 2020)
"Sevoflurane has been reported to involve in the progression in several cancers."1.62Sevoflurane inhibits the migration, invasion and induces apoptosis by regulating the expression of WNT1 via miR-637 in colorectal cancer. ( Chen, J; Duan, JA; Hu, N; Li, D; Yan, H; Yu, Y, 2021)
"However, the effects of sevoflurane on colorectal cancer (CRC) remains largely unclear."1.51Sevoflurane inhibits migration and invasion of colorectal cancer cells by regulating microRNA-34a/ADAM10 axis. ( Liu, J; Ren, LJ; Shan, SM; Sun, SQ; Wang, P, 2019)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's8 (53.33)24.3611
2020's6 (40.00)2.80

Authors

AuthorsStudies
Oh, CS1
Park, HJ2
Piao, L1
Sohn, KM1
Koh, SE1
Hwang, DY1
Kim, SH1
Lee, JE1
Chung, YJ1
Ahn, HJ1
Sim, WS1
Lee, JY1
Shao, Z1
Sun, L1
Lin, W1
Alexa, AL1
Ciocan, A1
Zaharie, F1
Valean, D1
Sargarovschi, S1
Breazu, C1
Al Hajjar, N1
Ionescu, D1
Aliev, VA1
Bashankaev, BN1
Loria, IZ1
Glabay, VP1
Yavorovsky, AG1
Shavgulidze, KB1
Yunusov, BT1
Buschmann, D1
Brandes, F1
Lindemann, A1
Maerte, M1
Ganschow, P1
Chouker, A1
Schelling, G1
Pfaffl, MW1
Reithmair, M1
Hu, N1
Duan, JA1
Yu, Y1
Li, D1
Chen, J1
Yan, H1
Fan, L1
Wu, Y1
Wang, J1
He, J1
Han, X1
Sun, SQ1
Ren, LJ1
Liu, J1
Wang, P1
Shan, SM1
Kopić, J1
Cascella, M1
Cascella, MM1
Arcamone, M1
Arcamone, MM1
Morelli, E1
Morelli, EE1
Viscardi, D1
Viscardi, DD1
Russo, V1
Russo, VV1
De Franciscis, S1
De Franciscis, SS1
Belli, A1
Belli, AA1
Accardo, R1
Accardo, RR1
Caliendo, D1
Caliendo, DD1
De Luca, E1
De Luca, EE1
Di Caprio, B1
Di Caprio, BB1
Di Sauro, F1
Di Sauro, FF1
Giannoni, G1
Giannoni, GG1
Iermano, C1
Iermano, CC1
Maciariello, M1
Maciariello, MM1
Marracino, M1
Marracino, MM1
Cuomo, A1
Cuomo, AA1
Chen, Y1
Liang, M1
Zhu, Y1
Zhou, D1
Beck-Schimmer, B2
Breitenstein, S1
Urech, S1
De Conno, E1
Wittlinger, M1
Puhan, M1
Jochum, W1
Spahn, DR1
Graf, R1
Clavien, PA1
Tylman, M1
Sarbinowski, R1
Bengtson, JP1
Kvarnström, A1
Bengtsson, A1
Müller-Edenborn, B1
Roth-Zʼgraggen, B1
Bartnicka, K1
Borgeat, A1
Hoos, A1
Borsig, L1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Role of Volatile Anesthetics for Hepatic Protection in Ischemia-reperfusion[NCT00516711]0 participants Interventional2006-03-31Completed
Pharmacological Preconditioning With Desflurane in Liver Surgery[NCT03848780]46 participants (Actual)Interventional2016-04-01Completed
Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Long-term Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT02660411]1,228 participants (Actual)Interventional2015-04-01Completed
Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on 5-year Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT05343260]1,228 participants (Actual)Interventional2015-04-01Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for sevoflurane and Colorectal Cancer

ArticleYear
Multidisciplinary approach and anesthetic management of a surgical cancer patient with methylene tetrahydrofolate reductase deficiency: a case report and review of the literature.
    Journal of medical case reports, 2015, Aug-20, Volume: 9

    Topics: Aged; Anesthesia; Anesthesia, Inhalation; Colorectal Neoplasms; Homocystinuria; Humans; Male; Methyl

2015

Trials

6 trials available for sevoflurane and Colorectal Cancer

ArticleYear
Expression Profiles of Immune Cells after Propofol or Sevoflurane Anesthesia for Colorectal Cancer Surgery: A Prospective Double-blind Randomized Trial.
    Anesthesiology, 2022, 03-01, Volume: 136, Issue:3

    Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Colorectal Neoplasms; Double-Blind Method;

2022
The Influence of Intravenous Lidocaine Infusion on Postoperative Outcome and Neutrophil-to-Lymphocyte Ratio in Colorectal Cancer Patients. A Pilot Study.
    Journal of gastrointestinal and liver diseases : JGLD, 2023, 06-22, Volume: 32, Issue:2

    Topics: Anesthetics, Local; Colorectal Neoplasms; Double-Blind Method; Humans; Infusions, Intravenous; Lidoc

2023
Volatile anaesthetics and cardiac protection in abdominal surgery.
    Wiener klinische Wochenschrift, 2015, Volume: 127, Issue:13-14

    Topics: Abdomen; Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Cardiotonic Agents; Colectomy; Col

2015
[The effect of propofol and sevoflurane on the perioperative immunity in patients under laparoscopic radical resection of colorectal cancer].
    Zhonghua yi xue za zhi, 2015, Nov-10, Volume: 95, Issue:42

    Topics: CD4-CD8 Ratio; Colorectal Neoplasms; Humans; Killer Cells, Natural; Laparoscopy; Methyl Ethers; Post

2015
A randomized controlled trial on pharmacological preconditioning in liver surgery using a volatile anesthetic.
    Annals of surgery, 2008, Volume: 248, Issue:6

    Topics: Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Colorectal

2008
A randomized controlled trial on pharmacological preconditioning in liver surgery using a volatile anesthetic.
    Annals of surgery, 2008, Volume: 248, Issue:6

    Topics: Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Colorectal

2008
A randomized controlled trial on pharmacological preconditioning in liver surgery using a volatile anesthetic.
    Annals of surgery, 2008, Volume: 248, Issue:6

    Topics: Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Colorectal

2008
A randomized controlled trial on pharmacological preconditioning in liver surgery using a volatile anesthetic.
    Annals of surgery, 2008, Volume: 248, Issue:6

    Topics: Adult; Aged; Alanine Transaminase; Anesthetics, Inhalation; Aspartate Aminotransferases; Colorectal

2008
Inflammatory response in patients undergoing colorectal cancer surgery: the effect of two different anesthetic techniques.
    Minerva anestesiologica, 2011, Volume: 77, Issue:3

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

2011

Other Studies

8 other studies available for sevoflurane and Colorectal Cancer

ArticleYear
Analgesic effect of dexmedetomidine in colorectal cancer patients undergoing laparoscopic surgery.
    Saudi medical journal, 2022, Volume: 43, Issue:10

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Colorectal Neoplasms; Dexmedetomidine; Fentanyl; Human

2022
Hexafluoro-2-propanol represses colorectal cancer proliferation by regulating transaminases.
    Acta biochimica Polonica, 2023, Feb-23, Volume: 70, Issue:1

    Topics: Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Sevofluran

2023
[Non-opioid multimodal anesthesia in the surgical treatment of colorectal cancer].
    Khirurgiia, 2019, Issue:8. Vyp. 2

    Topics: Analgesia, Epidural; Anesthetics, Inhalation; Colectomy; Colorectal Neoplasms; Humans; Laparoscopy;

2019
Propofol and Sevoflurane Differentially Impact MicroRNAs in Circulating Extracellular Vesicles during Colorectal Cancer Resection: A Pilot Study.
    Anesthesiology, 2020, Volume: 132, Issue:1

    Topics: Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Colorectal Neoplasms; Fe

2020
Sevoflurane inhibits the migration, invasion and induces apoptosis by regulating the expression of WNT1 via miR-637 in colorectal cancer.
    Anti-cancer drugs, 2021, 06-01, Volume: 32, Issue:5

    Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Gene Expressio

2021
Sevoflurane inhibits the migration and invasion of colorectal cancer cells through regulating ERK/MMP-9 pathway by up-regulating miR-203.
    European journal of pharmacology, 2019, May-05, Volume: 850

    Topics: Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Extracellular Signal-Regulated MAP Kinases; H

2019
Sevoflurane inhibits migration and invasion of colorectal cancer cells by regulating microRNA-34a/ADAM10 axis.
    Neoplasma, 2019, Volume: 66, Issue:6

    Topics: ADAM10 Protein; Amyloid Precursor Protein Secretases; Antineoplastic Agents; Cell Line, Tumor; Cell

2019
Volatile anesthetics reduce invasion of colorectal cancer cells through down-regulation of matrix metalloproteinase-9.
    Anesthesiology, 2012, Volume: 117, Issue:2

    Topics: Anesthetics, Inhalation; Colorectal Neoplasms; Desflurane; Down-Regulation; Enzyme-Linked Immunosorb

2012
Volatile anesthetics reduce invasion of colorectal cancer cells through down-regulation of matrix metalloproteinase-9.
    Anesthesiology, 2012, Volume: 117, Issue:2

    Topics: Anesthetics, Inhalation; Colorectal Neoplasms; Desflurane; Down-Regulation; Enzyme-Linked Immunosorb

2012
Volatile anesthetics reduce invasion of colorectal cancer cells through down-regulation of matrix metalloproteinase-9.
    Anesthesiology, 2012, Volume: 117, Issue:2

    Topics: Anesthetics, Inhalation; Colorectal Neoplasms; Desflurane; Down-Regulation; Enzyme-Linked Immunosorb

2012
Volatile anesthetics reduce invasion of colorectal cancer cells through down-regulation of matrix metalloproteinase-9.
    Anesthesiology, 2012, Volume: 117, Issue:2

    Topics: Anesthetics, Inhalation; Colorectal Neoplasms; Desflurane; Down-Regulation; Enzyme-Linked Immunosorb

2012